• Korean Journal of Psychosomatic Medicine
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• v.3 no.2
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• pp.126-138
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• 1995

For investigating a disease specific psychological mechanism in various dermatological disorders, we tried to explore the difference in correlation among stress perception, locus of control as a coping strategy, depressive symptoms and pruritic symptoms in the patients with psychological pruritis and chronic urticaria. The subjects were composed of 32 patients with psychol-ogical pruritis and 67 patients with chronic urticaria(subject group), and 25 patients with organic pruritis and 59 patient with major depression(control group). Global assesment of recent stress scale(GARS), I-E locus of control scale, Beck Depression Inventory(BDI) and medical college of wisconsin center pain follow up questionnaire were used for assesement. The results were as follows: 1) There were a significant positive correlation between stress perception and depressive symptom in patients with psychological pruritis, chronic urticaria, and major depression but not hi organic pruritis. 2) In relationship between locus of control and depressive symptom, patients with psychological pruritis, organic pruritis, and major depression except chronic ruticaria showed a significant negative correlation. 3) For intensity and pattern of pruritis, there were positive relations with depressive symptom and stress perception only in patients with chronic urticaria. Above results indicate that stress perception and locus of contorl may play a significant role in the formation of psychological and dermatological symptoms in psychological pruitis and chronic urticaria. But the mechanisms of these processes are different in either disorder.

• Plant Resources
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• v.5 no.2
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• pp.161-164
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• 2002

This study was performed to investigate the effect of Artemisiae argyi Herba extract on the treatment of chromaticity and colorfastness. Artemisiae argyi Herba has been used as a Korean medicine. It is effective in removing skin disorders and suppressing pain. It is also good as a fungicide and in treating pruritis. In the long history of Korea, dyeing has been applied for a means representing the grace of natural and inner esthetic consciousness of man. Vegetable dyes give us such great benefits, diversified color; but no pollution. And ramie fabric has distinctive features such as beautiful brilliance, elegance, and strong durability. So, it is regarded as a special product of Korea traditionally. These studies were carried out to treat with acetate iron, dichloride copper and alum with a mordant to ramie fabric. The ramie fabric was died with Artemisiae argyi Herba extract. The results of experiment showed as follows: First, the chromophoric degree was the highest in acetate iron but not distinction in another mordants. Seocond, the light colorfastness was the highest in non treated and dichloride copper, but alum was the lowest. Third, the discoloration was alum and dichloride copper showed first grade in washing colorfastness. Abrasion colorfastness was not significant in this test. According the previous results, Artemisiae argyi Herba has an efficiency in removing skin disorders and suppressing pain. So it is considered that Artemisiae argyi Herba can be applied effectively to theraphy of fungicide and in treating pruritis.

• Herbal Formula Science
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• v.21 no.1
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• pp.200-205
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• 2013

Objectives : The purpose of this study is to report the clinical effectiveness of herbal remedies (Bokryeongkamcho -tang. Yeongkyechulkam-tang.) on nummular eczema. Methods : The 49 year-old male patient has been suffered from nummular eczema for 8 months. At first, he was treated with Bokryeongkamcho-tang for 56 days. And then he was treated with Yeongkyechulkam-tang for last 40 days. During the treatment we checked pruritis degree changes and extent changes by asking. And we checked how prulent exudates, crusts, scratch marks are changes by taking photos. First evaluation was performed before treatment, second evaluation was performed after taking Bokryeongkamcho-tang 56 days, third evaluation was performed after taking Yeongkyechulkam-tang 40 days. Results : After taking Bokryeongkamcho-tang 56 days, pruritus was decreased and prulent exudents were stopped, and crusts were disappeared. Nummular eczema on trunk, arm, thigh was disappeared. But light pruritis was still going on, and small circle-shaped vesicles groups were lagged on forearm and shin, ankle. So we found other symptoms from the patient, and administered Yeongkyechulkam-tang. After taking Yeongkyechulkam-tang 40 days, pruritus was almost decreased and nummular eczema on fore arm, shin was disappeared. Conclusions : This clinical case indicates that herbal remedies(Bokryeongkamcho-tang. Yeongkyechulkam-tang.) are effective on nummular eczema.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.243-250
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• 2014

Objective : The purpose of this report is to know the effect of oriental medical treatments on acute allergic contact dermatitis with multiple nummular eczema. Methods : We treated a 34-years-old woman patient with acute allergic contact dermatitis on face and multiple nummular eczema on both arm, right ankle and left inguinal region by Korean medicine. After Korean medical treatment for 42 days in hospital, we measured the decrease of exudation and pruritis as well as recovery of skin damages. We recorded pictures of changes on symptoms. Results & Conclusion : The symptoms of ACD and nummular eczema were significantly improved except scars. Exudation and pruritis were disappeared and skin damages were almost recovered until discharge from hospital. After 20 days we could confirm the symptoms were clearly disappeared. Thus Korean medical treatments are effective on ACD and nummular eczema.

• CELLMED
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• v.9 no.2
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• pp.1.1-1.4
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• 2019

Pruritic urticarial papules and plaque of pregnancy presents with difficulty in its management owing to the limited intervention options available during pregnancy and their sub optimal responses. In pregnancy, also often the mother remains reluctant in getting exposed to biological medicines for her concern to the growing fetus. In such conditions, Ayurveda, the traditional health care system from India is often looked as a safe alternative to offer symptom resolution and safe continuation of pregnancy without the discomforts of urticaria. This case report is an illustration in this regard.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1781-1786
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• 2013

Objective: The study was designed to assess the skin and subcutaneous toxicity in patients with advanced colorectal carcinoma treated with four different schedules of FOLFOX. Methods: The patients with histologically confirmed advanced colorectal carcinoma (CRC) were included in the study as per specified inclusion criteria. Toxicity was graded according to CTC v2.0. The frequency of grade 3 and 4 adverse effects were comparatively assessed in each treatment arm. Results: Very severe toxicity was attributed to the FOLFOX7 schedule. The difference between the incidence rate of grade 4 toxicity with all other grades for all parameters of skin and subcutaneous toxicity was highly significant (p=0.00<0.001). Grade 4 hand and foot syndrome was reported only in the FOLFOX7 treatment arm. The most frequent adverse symptom of skin and subcutaneous toxicity reported in the patients treated with modified schedule of FOLFOX was pruritus (grade 1). Frequency and onset of skin and subcutaneous toxic symptoms like alopecia (p=0.000), nail discoloration (p=0.021) and pruritis (p=0.000) was significantly different in each FOLFOX treatment arm. A few cases of oncholysis were also reported in the FOLFOX7 treatment arm. Hand and foot syndrome was fast progressing in patients with grade 1 toxicity. Conclusion: Higher frequency and severity of hand and foot syndrome and pruritus wasa found in the FOLFOX7 treatment arm. Skin and subcutaneous toxicity was comparatively low in the FOLFOX6 treatment arm.

• Physical Therapy Korea
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• v.3 no.1
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• pp.73-79
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• 1996

Photochemotherapy(UVA with 8-methoxypsoralen) was given to 30 patients with systemic psoriasis. The results of clearing and long-term(6-month) interval maintenance were reported. Clearing requirements were in general similar to these reported by Melski and Burger. The skin of the 14 patients (46.6%) recovered good skin condition by a once weekly maintenance dose. This result was better than that reported by other authors. 1. During initial treatment period, average number of treatment was 27.3 and average duration treatment was 24.8 weeks. 2. The factors to quit treatment were motion decrease, moving to the remote area, complications, etc. 3. Number of patient who received maintenance treatment was 14. 4. The complications reported from the patients were hyperpigmentation, nausea, headache, pruritis, vomiting, gastritis.

• The Korean Journal of Pain
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• v.9 no.1
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• pp.244-247
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• 1996

A 67 year old male with postherpetic neuralgia complained of right anterior chest throbbing pain and also allodynia. We performed thoracic epidural block with 0.25% bupivacaine and 1% lidocaine. Oral carbamazepine and imipramine were also administred concomitantly. One month later, patient complained of fatigue, anorexia, pruritis, jaundice, and dark urine. Liver function test values were significantly elevated then. Therefore we removed the epidural catheter and ceased all medication. Liver function test values decreased rapidly after discontinuation of medication. Hepatitis might have developed as result of drugs administered and could have been prevented if the patient had been monitored with regular clinical laboratory follow up. The purpose of this case report is emphasize the importance of early regular laboratory test to detect any possible side effect that may occur by administration of drugs during treatment of chronic pain.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.250-255
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• 2007

Molluscum contagiosum(MC) is a viral disorder of the skin and mucous membranes characterized by decrete single or multiple, flesh-colored papules. There was the 6 years old woman who suffered from umbilicated papules and pruritis of back. First, Her mother choiced western medicine, and was treatded with topical(ointment applicatoin) and surgical(curettage) method. Despite of western medical treatment during 3 months, there was not recovery of symptoms. So, she visited the Dept. of Opthalmology & Otorhinolaryngology & Dermatology, College of Oriental Medicine, Kyungwon University for oriental medical treatment. The oriental medical treatment reduced the symptoms of the patient remarkably during 8weeks. So we report the healing process and result of this patient in this study. There is few report that treat MC with oriental medical method. If more clinical trials like this are proved to be effective, we can expect that oriental medical treatment will be a good method in MC.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.2
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• pp.55-63
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• 2004

Objectives : This study was designed to identify the possibility of aroma oils as the complementary medical goods specially for the effects of aromatheraphy on xerosis cutis. Materials and Methods : The participants were 23 adult patients and all participants of this study use aroma oils which is known to effect on xerosis cutis. The subjects consist of voluntary patients with xerosis cutis in Seong-So Hospital in Andong Kyoungbuk, Korea. From April 1st to April 30th, 2004 for 4 weeks, the subjects massaged aroma oils on itching parts or the whole body. Aroma oils were Lavender, Losemary, Jasmine and blended drop by drop per 10ml jojoba oil which used a carrier oil. Skin pH was measured with a skin pH meter(Model : HI98110, Se-Chang instruments, made in Portuga. After 4weeks using aroma oils, the participants answered questions about the feeling of satisfaction with aroma oils. Results : Changes in the physiological indices. The mean deviation of skin pH was $5.58{\pm}0.47$ points before using aroma oils and $5.53{\pm}0.45$ points after 2 weeks, no statistical significance was found(p=0.221). MD was $5.36{\pm}0.41$ points after 4 weeks using aroma oils, which was statistically significant decrease of 0.22 points(p=0.001) Changes on the Pruritus Score Scale. A modified scale of the Pruritus Score Scale(Duo, 1987) was used to measure the severity, location, frequency, and the inconveniences of daily life due to prurius. The maximum scale of severity was 4 points, the full marks of location was 2 points, the full marks of frequency was 3 points, the full marks of inconveniences of daily life due to pruritus was 3 points. The scores ranged from 0 to 12, with 12 indicating the most severe pruritus. There was no statistical difference in severity and frequency score at 4 weeks later(severity p=0.097, frequency p=0.633). A statistically significant difference was found in the score of location and the inconveniences of daily life due to pruritus(each p=0.003). Conclusion : Generally speaking, the patient suffering from renal itch is the higher than normal in skin pH levels. that means to show alkaline condition of skin surface. In some case in this study, skin pH levels was rather lower than normal levels when measured actually patients suffering from renal itch by skin pH meter. But in this study post-test skin pH levels decreased, showing the contribution of aromathrapy to acidic condition of skin surface in suffering from renal itch. It seems to be some help to cure a pruritus and also have no ill effects on aroma oils.