• Title/Summary/Keyword: protective-stabilizing function

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Protective-stabilizing function of parenting process and school process in the Relationship Between Adolescents' academic achievement and self-evaluation (청소년의 학업성취와 자아평가의 관계에서 부모과정과 학교과정의 보호적-안정화 기능)

  • Jung, Hyun-Ju;Lee, Ju-Rhee
    • Korean Journal of Human Ecology
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    • v.18 no.3
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    • pp.609-618
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    • 2009
  • The study examined the effects of parenting process(supportive and involving mother-adolescent relationship, father-adolescent relationship) and school process(teachers' support, school life satisfaction) on adolescents' academic achievement and self-evaluation. Participants were 1787 middle school students (902 boys, 885 girls) in KEEP(Korean Education and Employment Panel). Structural equation modeling indicated that parenting and school process influenced adolescents' self-evaluation through adolescents' academic achievement. Also, the analysis with One Way ANOVA revealed that positive school (parenting) processes can serve a protective-stabilizing function when parenting(school) processes are negative.

Heat shock protein 90β inhibits apoptosis of intestinal epithelial cells induced by hypoxia through stabilizing phosphorylated Akt

  • Zhang, Shuai;Sun, Yong;Yuan, Zhiqiang;Li, Ying;Li, Xiaolu;Gong, Zhenyu;Peng, Yizhi
    • BMB Reports
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    • v.46 no.1
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    • pp.47-52
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    • 2013
  • Intestinal epithelial cell (IEC) apoptosis induced by hypoxia compromise intestinal epithelium barrier function. Both Akt and Hsp90 have cytoprotective function. However, the specific role of Akt and $Hsp90{\beta}$ in IEC apoptosis induced by hypoxia has not been explored. We confirmed that hypoxia-induced apoptosis was reduced by $Hsp90{\beta}$ overexpression but enhanced by decreasing $Hsp90{\beta}$ expression. $Hsp90{\beta}$ overexpression enhanced BAD phosphorylation and thus reduced mitochondrial release of cytochrome C. Reducing $Hsp90{\beta}$ expression had opposite effects. The protective effect of $Hsp90{\beta}$ against apoptosis was negated by LY294002, an Akt inhibitor. Further study showed that Akt phosphorylation was enhanced by $Hsp90{\beta}$, which was not due to the activation of upstream PI3K and PDK1 but because of stabilization of pAkt via direct interaction between $Hsp90{\beta}$ and pAkt. These results demonstrate that $Hsp90{\beta}$ may play a significant role in protecting IECs from hypoxia-induced apoptosis via stabilizing pAkt to phosphorylate BAD and reduce cytochrome C release.

Development of power system stabilization program using optimization method (최적화 기법이 적용된 전력계통 안정화 시스템 개발)

  • Ahn, Chang-Han;Baek, Young-Sik
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.3
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    • pp.370-374
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    • 2015
  • Various protective equiptments are used for the power system control and protection. Numerous facilities are monitored at the same time in real time and introduction of optimization method and analysis of the method are required for generation control and facility management considering the demand fluctuations. However, the existing system analysis programs are difficult to link with the other sw and there are some problems with user convenience. To solve these problems the present conditions of the system are figured out in real time and the equipment insert method was estimated by optimization method, and the system that showed the system analysis program is developed. PSS/E has been used as system anlysis program for stabilizing system development which applied the optimization. method and Python language is applied in order to link the input and output values with the DB automatically. Lastly, DLL of matlab has been made included in C++ for solving the objective function using opmization method.By linking this to DB, power flow was calculated in PSS/E and the result was represented by Intouch screen.

Architectural Planning Study on Spatial Composition of Mobile Seclusion Module - Based on Modular Construction System (이동형 안정실 모듈의 공간구성에 대한 건축계획적 연구 - 모듈러 건축 공법을 기반으로)

  • Kim, Sung Hyun;Yang, Nae-won
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.29 no.2
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    • pp.49-60
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    • 2023
  • Purpose: This study aims to establish detailed spatial planning by identifying the needs for a seclusion module for emergency psychiatric patients. Methods: The necessity of medical space with seclusion function was analyzed from spatial, medical, and social perspectives. The needs for a space capable of performing three medical functions: protection, isolation, and treatment, was analyzed. Among various types of mobile medical facilities, seclusion space was considered suitable for utilizing modular construction methods, as it is the most rational method that can satisfy the environmental level of fixed healthcare facilities' space. Therefore, seclusion modules based on modular construction were planned, consisting of two protective units for stabilizing patients with psychiatric illness, one for treatment unit that can accommodate both internal and external treatment, and another one for an infectious disease isolation unit equipped with negative pressure equipment. Implications: This study analyzed the necessary medical functions of the interior space of the mobile stabilization module based on the spatial analysis of existing medical facilities, and proposed alternative spatial configurations according to treatment, seclusion, isolation functions.