• 제목/요약/키워드: protective and risk factors

검색결과 262건 처리시간 0.032초

Risk Factors for COVID-19 Infection Among Healthcare Workers. A First Report From a Living Systematic Review and meta-Analysis

  • Dzinamarira, Tafadzwa;Nkambule, Sphamandla Josias;Hlongwa, Mbuzeleni;Mhango, Malizgani;Iradukunda, Patrick Gad;Chitungo, Itai;Dzobo, Mathias;Mapingure, Munyaradzi Paul;Chingombe, Innocent;Mashora, Moreblessing;Madziva, Roda;Herrera, Helena;Makanda, Pelagia;Atwine, James;Mbunge, Elliot;Musuka, Godfrey;Murewanhema, Grant;Ngara, Bernard
    • Safety and Health at Work
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    • 제13권3호
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    • pp.263-268
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    • 2022
  • Health care workers (HCWs) are more than ten times more likely to be infected with coronavirus infectious disease 2019 (COVID-19) than the general population, thus demonstrating the burden of COVID-19 among HCWs. Factors that expose HCWs to a differentially high-risk of COVID-19 acquisition are important to elucidate, enable appropriate public health interventions to mitigate against high risk and reduce adverse outcomes from the infection. We conducted a systematic review and meta-analysis to summarize and critically analyze the existing evidence on SARS-CoV-2 risk factors among HCWs. With no geographical limitation, we included studies, in any country, that reported (i) the PCR laboratory diagnosis of COVID-19 as an independent variable (ii) one or more COVID-19 risk factors among HCWs with risk estimates (relative risk, odds ratio, or hazard ratio) (iii) original, quantitative study design, and published in English or Mandarian. Our initial search resulted in 470 articles overall, however, only 10 studies met the inclusion criteria for this review. Out of the 10 studies included in the review, inadequate/lack of protective personal equipment, performing tracheal intubation, and gender were the most common risk factors of COVID-19. Based on the random effects adjusted pooled relative risk, HCWs who reported the use of protective personal equipment were 29% (95% CI: 16% to 41%) less likely to test positive for COVID-19. The study also revealed that HCWs who performed tracheal intubations were 34% (95% CI: 14% to 57%) more likely to test positive for COVID-19. Interestingly, this study showed that female HCWs are at 11% higher risk (RR 1.11 95% CI 1.01-1.21) of COVID-19 than their male counterparts. This article presents initial findings from a living systematic review and meta-analysis, therefore, did not yield many studies; however, it revealed a significant insight into better understanding COVID-19 risk factors among HCWs; insights important for devising preventive strategies that protect them from this infection.

Role of Vitamin D Deficiency and Lack of Sun Exposure in the Incidence of Premenopausal Breast Cancer: a Case Control Study in Sabzevar, Iran

  • Bidgoli, Sepideh Arbabi;Azarshab, Hamid
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권8호
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    • pp.3391-3396
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    • 2014
  • Background: Vitamin D has been suggested as one of the critical factors for female reproductive health with protective activities against different cancers but there are conflicting facts regarding its role on breast cancer without any clear data on premenopausal cases. This study aimed to evaluate the role of vitamin D from dietary sources and sunlight exposure on the incidence of premenopausal breast cancer. Materials and Methods: We conducted a case control study on 60 newly diagnosed premenopausal breast cancer patients and 116 normal women who lived in Sabzevar and surrounding villages in Razavi, Khorasan, a rural and conservative area of Iran. Results: The mean concentrations of 25-OH vitamin D in cases and controls were $15.2{\pm}8.15$ vs $15.5{\pm}7/45ng/ml$, both well below normal values elsewhere. In fact 50% of analyzed individuals showed very severe or severe vitamin D deficiency and the rest (25%) were detected in suboptimal levels. Although the lack of vitamin D and calcium supplementation increased slightly the risk of premenopausal breast cancer (p=0.009, OR=1.115, CI 95%=1.049-1.187), higher prevalence of weekly egg consumption (86.66% vs 96.55%, p=0.023, OR=0.232, CI 95% 0.065-0.806) showed a slight protective role. The last but the most important risk factor was lack of sunlight exposure because the breast cancer patients had total body coverage from sun (p=0.007, OR=10.131, CI 98% 0.314-78.102). Conclusion: This study pointed out the role of vitamin D and other possible risk factors on the development and growth of breast tumors in this special geographical region. Although this study has revealed the interactions between hormonal and environmental factors in this province of Iran, understanding the deficiency pattern and its contribution to other lifestyle factors elsewhere is also necessary.

임상가를 위한 특집 3 - 우식위험도 평가에 근거한 치아우식증 관리의 임상적용 사례 및 활성화 방안 (The clinical application of dental caries management based on caries risk assessment and activation strategies)

  • 윤홍철;최연희
    • 대한치과의사협회지
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    • 제52권8호
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    • pp.472-477
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    • 2014
  • The new paradigm of dentistry require the detection of caries in their earlier stages. To achieve this, a high technology detection device and systematic and organized caries management system are needed. Caries management by risk assessment (CAMBRA) model is representative caries management system that satisfied new paradigm. Dental caries prevention and treatment according to CAMBRA model is patient-centered, risk-based, evidence-based practice. Therefore, individual caries management such as CAMBRA should be performed through accurate assessment of caries disease indicators and comprehensive assessment of caries risk factors and protective factors. Based on the CAMBRA better effectiveness of comprehensive dental caries management including non-surgical treatment will be accomplished.

Risk Factors of Breast Cancer among Women in Eastern India: A Tertiary Hospital Based Case Control Study

  • Das, Soumen;Sen, Santanu;Mukherjee, Anindya;Chakraborty, Debadatta;Mondal, Pankaj Kumar
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.4979-4981
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    • 2012
  • Aim: Breast cancer is one of the most common cancers of women in India with high fatality rate. Over a 1 year study period 105 consecutive biopsy or fine needle aspiration cytology confirmed breast cancer patients were interviewed by direct questionnaire method regarding risk factors attending Surgery and Radiotherapy OPD of Medical College Kolkata, West Bengal while taking other 105 patients attending Surgery Department for some other disease as controls. The data were compiled in MS Excel 2007 and analyzed by Epi info 3.5.1 software. Among the cases, rural residence, illiteracy and low socio-economic status was significantly higher than controls. Late onset of menarche, late onset of menopause, ever OCP usage, breast feeding for 1-2 years and age of 1st childbirth between 20-30 years were found to be significant protective factors. People should be made aware regarding the modifiable risk factors to prevent breast cancer.

Risk Factors of Breast Cancer in the Eastern Mediterranean Region: A Systematic Review and Meta-Analysis

  • Namiranian, Nasim;Moradi-Lakeh, Maziar;Razavi-Ratki, Seid Kazem;Doayie, Mahdyie;Nojomi, Marzieh
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권21호
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    • pp.9535-9541
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    • 2014
  • Background: Identifying risk factors of breast cancer is a key point for preventive strategies to reduce the incidence. The aim of current study was to determine most important risk factors for breast cancer in the Eastern Mediterranean Region (EMR) using a systematic review. Materials and Methods: PubMed, Scopus, Web of Science till August 24, 2012 and the reference lists of all included studies were searched. Analytic studies which had reported odds ratios (OR), relative risk (RR) or required data to calculate them were included. A total of 343 studies were critically appraised and finally 30 studies were meta-analyzed. Heterogeneity between the studies was assessed by $I^2$ and Cochran's Q. Egger's test was used to assess publication bias. Results: Twenty five casecontrol studies, one nested case-control and four cohort studies were included. The largest ORs were obtained for history of no live birth (2.25; 95%CI: 1.58-3.18), body mass index (BMI) more than 30 (2.21; 95%CI: 1.71-2.36), age at first pregnancy more than 30 years old (1.52; 95%CI: 1.30-1.77) and meat consumption more than three times per week (1.39; 95%CI: 1.03-1.87). The other important predictors were higher education and smoking as risk factors, physical activity and ovulatory stimulating medication as protective factors. Conclusions: The most important predictors of breast cancer in EMR were history of no live birth, BMI more than 30, age at first pregnancy more than 30 years old, physical inactivity and smoking. Almost all these risk factors are consistent with known risk factors for this cancer in other parts of the world.

머신러닝을 활용한 대학생 중도탈락 위험군의 예측모델 비교 연구 : N대학 사례를 중심으로 (A Comparative Study of Prediction Models for College Student Dropout Risk Using Machine Learning: Focusing on the case of N university)

  • 김소현;조성현
    • 대한통합의학회지
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    • 제12권2호
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    • pp.155-166
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    • 2024
  • Purpose : This study aims to identify key factors for predicting dropout risk at the university level and to provide a foundation for policy development aimed at dropout prevention. This study explores the optimal machine learning algorithm by comparing the performance of various algorithms using data on college students' dropout risks. Methods : We collected data on factors influencing dropout risk and propensity were collected from N University. The collected data were applied to several machine learning algorithms, including random forest, decision tree, artificial neural network, logistic regression, support vector machine (SVM), k-nearest neighbor (k-NN) classification, and Naive Bayes. The performance of these models was compared and evaluated, with a focus on predictive validity and the identification of significant dropout factors through the information gain index of machine learning. Results : The binary logistic regression analysis showed that the year of the program, department, grades, and year of entry had a statistically significant effect on the dropout risk. The performance of each machine learning algorithm showed that random forest performed the best. The results showed that the relative importance of the predictor variables was highest for department, age, grade, and residence, in the order of whether or not they matched the school location. Conclusion : Machine learning-based prediction of dropout risk focuses on the early identification of students at risk. The types and causes of dropout crises vary significantly among students. It is important to identify the types and causes of dropout crises so that appropriate actions and support can be taken to remove risk factors and increase protective factors. The relative importance of the factors affecting dropout risk found in this study will help guide educational prescriptions for preventing college student dropout.

청소년 비행행동의 궤적에 영향을 미치는 보호요인과 위험요인 (Influence of Protective and Risk Factors on Delinquent Behavior Trajectories)

  • 이상균
    • 사회복지연구
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    • 제39호
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    • pp.315-342
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    • 2008
  • 본 연구는 청소년패널조사의 1-4차년도 종단자료를 이용하여 비행행동의 발달궤적을 확인하고자 하였다. 다층모형분석(HLM)에 기반한 성장곡선모형을 이용하여 비행행동의 수준과 변화율을 추정하였다. 중학교 2학년에서 측정한 보호 및 위험요인이 최종 측정시점에서의 비행행동 수준과 변화율에 어떠한 영향을 미치고 있는지 확인해 보았다. 연구모형에서 상정한 보호 및 위험요인은 부모의 양육행동, 자기통제력, 비행친구와의 교류, 부정적 낙인 등이었다. 성별과 가구의 사회경제적 배경변인이 통제변인으로 포함되었다. 분석결과, 성별과 부모의 학력, 가구소득은 비행행동의 수준과 변화율에 유의미한 영향을 미치는 것으로 나타났다. 빈곤가족이면서 남자청소년일 경우, 청소년 후기에 비행행동을 경험할 가능성은 높았고, 그 증가세도 가파른 것으로 나타났다. 아울러 부모와의 애착관계를 제외한 모든 보호(위험) 요인이 비행행동의 수준에 유의미한 영향을 미치는 것으로 나타났다. 보호(위험) 요인들은 이론들이 예측하는 방향과 일치하는 결과로 비행행동에 대해 억제 또는 강화하는 효과를 가지는 것으로 나타났다. 비행행동의 변화율과 관련하여 유의미한 영향을 미치는 것으로 확인된 보호 및 위험요인은 자기통제력과 비행친구와의 교류로 나타났다. 비행친구와의 교류가 적었던 청소년들의 비행행동 증가율은 더 높은 것으로 나타났고, 자기통제력이 높은 청소년의 경우 시간이 지남에 따라 비행행동의 증가율은 상대적으로 완만하게 나타났다. 보호 및 위험요인이 비행행동의 궤적에 미치는 영향을 종단자료를 통해 분석한 결과에 기반하여 청소년의 비행행동 예방 및 개입을 위한 실천적 함의를 살펴보았고, 필요한 후속연구의 과제에 대해 제시하였다.

UWB 기반 측위시스템을 이용한 연안자망어선 어선원의 작업위치와 위험요소 (Risk factors and fisher positioning task during coastal gillnet fishing boat operation using UWB based positioning system)

  • 류경진;김수형;이경훈;김성훈;원성재;이유원
    • 수산해양기술연구
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    • 제60권2호
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    • pp.152-160
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    • 2024
  • We analyzed risk factors of coastal gillnet fishers during fishing process and considered work safety measures to reduce safety accidents during fishing using a UWB (ultra wideband) based positioning system. The static position accuracy of the UWB based positioning system was 45 cm. When entering a port, there is a risk of falling overboard. When casting a net, there was a risk of falling overboard due to being hit by fishing gear or guards, or getting caught in a buoy line or sinker line. When hauling a net, there is a risk of getting caught between fishing gear and net hauler, and the risk of musculoskeletal disorders due to repetitive work over a long period of time. Most safety accidents during work on fishing boats are blamed on human errors of the fisher and skipper, but safety accidents occur due to a mixture of mechanical and equipment factors, work and environmental factors, and management factors in addition to human errors. Therefore, the 4E were presented as countermeasures against the 4M, which are causes of safety accidents, and the proposed measures were used to identify risk factors for operation process, comply with work safety rules, and ensure the wearing of personal protective equipments. We need to reduce safety accidents during work by making it part of our daily routine. These research results can be used in the future for optimal placement of fishing gear and fishing nets in other coastal industries where safety accidents occur frequently.

인문계 고등학생의 학업문제가 자살생각에 미치는 영향 -개인수준의 위험요인과 보호요인의 매개역할을 중심으로- (The Effects of High School Students' Academic Problems on Suicidal Ideation -Focusing on the Mediational Effects of Individual-level Risk and Protective Factors-)

  • 박재연;정익중
    • 한국아동복지학
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    • 제32호
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    • pp.69-97
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    • 2010
  • 이 연구는 청소년의 학업과 관련된 문제인 학업스트레스와 낮은 성적이 자살생각에 미치는 영향 관계와 그 관계에서 개인수준의 위험요인인 우울과 공격성, 개인수준의 보호요인인 자아존중감과 감정조절의 매개효과를 검증하는 것을 목적으로 한다. 이를 위해 한국청소년패널조사(KYPS)의 3개년도(2005년~2007년) 자료를 이용하였으며, 인문계 고등학교에 재학 중인 총 2,093명 학생의 설문지를 기초로 분석하였다. 구조방정식모형을 통해 자료를 분석한 결과, 학업스트레스는 우울과 공격성에 정적(+) 영향을 미치고 있었으며, 자아존중감에 부적(-) 영향을 미치고 있었다. 낮은 성적은 공격성에 정적 영향을, 자아존중감에 부적 영향을 미치고 있었다. 또한 매개변수인 우울과 공격성은 청소년 자살생각에 미치는 정적 영향이, 자아존중감과 감정 조절은 청소년 자살생각에 미치는 부적 영향이 유의미한 것으로 나타났다. 이에 학업스트레스가 청소년 자살생각에 미치는 영향에서 우울과 공격성, 자아존중감이 유의미한 매개역할을 하는 것이 밝혀졌으며, 공격성과 자아존중감은 낮은 성적이 청소년 자살생각에 미치는 영향관계를 매개하는 것으로 나타났다. 본 연구에서 검증된 개인수준의 위험요인들과 보호요인들을 사전에 파악하여 선별 치료해 나간다면 청소년들이 학업문제를 감당하지 못해 선택하는 가장 극단적인 방법인 자살에 이르는 것을 사전에 예방하는 데 도움이 될 것이다.

The Correlation of Serum Osteoprotegerin with Non-Traditional Cardiovascular Risk Factors and Arterial Stiffness in Patients with Pre-Dialysis Chronic Kidney Disease: Results from the KNOW-CKD Study

  • Chae, Seung Yun;Chung, WooKyung;Kim, Yeong Hoon;Oh, Yun Kyu;Lee, Joongyub;Choi, Kyu Hun;Ahn, Curie;Kim, Yong-Soo
    • Journal of Korean Medical Science
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    • 제33권53호
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    • pp.322.1-322.14
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    • 2018
  • Background: Osteoprotegerin (OPG) plays protective roles against the development of vascular calcification (VC) which greatly contributes to the increased cardiovascular events in patients with chronic kidney disease (CKD). The present study aimed to find the non-traditional, kidney-related cardiovascular risk factors correlated to serum OPG and the effect of serum OPG on the arterial stiffness measured by brachial ankle pulse wave velocity (baPWV) in patients with the pre-dialysis CKD. Methods: We cross-sectionally analyzed the data from the patients in whom baPWV and the serum OPG were measured at the time of enrollment in a prospective pre-dialysis CKD cohort study in Korea. Results: Along with traditional cardiovascular risk factors such as age, diabetes mellitus, pulse pressure, and baPWV, non-traditional, kidney-related factors such as albuminuria, plasma level of hemoglobin, total $CO_2$ content, alkaline phosphatase, and corrected calcium were independent variables for serum OPG in multivariate linear regression. Reciprocally, the serum OPG was positively associated with baPWV in multivariate linear regression. The baPWV in the 3rd and 4th quartile groups of serum OPG were higher than that in the 1st quartile group after adjustments by age, sex and other significant factors for baPWV in linear mixed model. Conclusion: Non-traditional, kidney-related cardiovascular risk factors in addition to traditional cardiovascular risk factors were related to serum level of OPG in CKD. Serum OPG level was significantly related to baPWV. Our study suggests that kidney-related factors involved in CKD-specific pathways for VC play a role in the increased secretion of OPG into circulation in patients with CKD.