• Title/Summary/Keyword: prosapogenins acid-cataly-zed transformation

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The transformation of ginsenosides by acid catalysis in gastric pH

  • Han, Byung-Hoon;Park, Myung-Hwan;Han, Yong-Nam;Woo, Lin-Keun;Ushio-Sankawa;Shoji-Yahara;Osamu-Tanaka
    • Archives of Pharmacal Research
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    • v.4 no.1
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    • pp.25-31
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    • 1981
  • The ginsenosides of Korean ginseng decomposed profoundly to produce artifact products of prosapogenin $A_{1}$, $A_{2}$ and $A_{3}$ from ginsenoside Rg$_{1}$, prosapogenin $C_{1}$, $C_{2}$ and $C_{3}$ from ginsenoside Re, and prosapogenin E$_{1}$, E$_{2}$ and E$_{3}$ from ginsenoside Rb$_{1}$ by the acid treatment under physiological condition such as 37.deg.C incubation in 0.1 N HCI. 2. The chemical structures of the artifact substances were determined by the analysis CMR and mass spectra of TMS derivatives as following; table omitted.

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