• 대한지리학회지
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• 제38권1호
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• pp.70-86
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• 2003

이 연구는 안동의 이른바 음택명당 풍수 경관에 대하여 조사하여 그 형태와 특징을 살펴보고자 한다. 안동문화원에서 펴낸 $\ulcorner$안동의 분묘$\lrcorner$에 나오는 분묘와 예천의 일부 묘지를 대부분 야외조사하고, 이 중에서 형기론적 입장에서 나타난 다양한 명당의 특징을 1:25,000지형도 상에서 기술한다. 안동지역은 낙동강, 반변천, 길안천의 수많은 지류가 흐르고 그 주위에 낮은 구릉, 완만한 사면 및 높은 배후 산지가 전개되며 수많은 명당이 입지한다고 알려져 왔다. 연구 결과는 다음과 같다. 안동의 경우는 날짐승(봉, 학, 꿩), 꽃(모란, 연꽃, 칡넝쿨), 길짐승(닭), 들짐승(거북, 뱀). 물건(등잔, 가마솥, 밥상), 용, 달 등의 형기론적 명당이 나타나며, 이들 형태는 크게 낙동강 본류 이북 쪽에 집중한다. 이들 명당은 고도 상으로 해발고도 100m∼400m 부근에 대부분 입지한다. 이들 명당의 공통된 형태적 특징은 반개방성, 중첩성. 안정성. 조화성, 균형성이다. 형태 상의 이러한 특징은 풍수지리의 원리를 오늘날의 입지 선정에 적용할 수 있는 근거를 갖게 하는 것이다.

• 대한상부위장관⦁헬리코박터학회지
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• 제18권3호
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• pp.157-161
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• 2018

Liquid biopsy, the analysis of circulating biomarkers from peripheral blood, such as circulating tumor cells (CTCs) and circulating tumor DNA, and exosomes, offers a less invasive, new source of cancer-derived materials that may reflect the status of the disease better and thereby contribute to personalized treatment. Recent advances in microfluidics and molecular analysis technologies have resulted in greatly improved CTC enumeration and detection. In this article, we review commercially available technologies used to isolate CTCs from peripheral blood, including immunoaffinity and label-free, physical property-based isolation methods. Although enormous technological progress has been made, especially within the last decade, only a few CTC detection methods have been approved for routine clinical use. Here, we provide an overview of the current CTC isolation methods and examples of their potential application for early diagnosis, prognosis, treatment monitoring, and prediction of resistance to cancer therapy. Furthermore, the challenges that remain to be addressed before such tools are implemented for routine use in clinical settings are discussed.

• 환경영향평가
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• 제20권4호
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• pp.497-507
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• 2011

This research studied human health risk assessment of benzene from industrial complexes of Chungcheong Province (Seosan industrial complex) and Jeonla Province (Iksan industrial complex and Yeosoo industrial complex). The residents near the industrial complexes areas can be often exposed to volatile organic compounds (e.g., benzene, toluene, xylenes) through a number of exposure pathways, including inhalation of the organic pollutant via various environmental matrices (air, water and soil), contaminated water, and soil intake. Benzene is well known to be a common carcinogenic and toxic compound that is produced from industrial and oil refinery complexes. In this study, a number of samples from water, air, and soil were taken from the residential settings and public school zones located near the industrial complex sites. Based on the carcinogenic risk assessment, the risk estimates were slightly above $10{\times}10^{-6}$ at all three industrial sites. According to deterministic risk assessment, inhalation was the most important route. The distribution of benzene in the environment would be dependent on vapor pressure, and the physical property influencing the extent of the potential risks. Non-carcinogenic risk assessment of benzene shows that the values of Hazard Index(HI) were much lower than 1.0 at all industrial complexes. Therefore, benzene was not a cause of concern in terms of non-carcinogenic risk posed to the residents near the sites. When compared to probabilistic risk assessment, the CTE(central tendency exposure) cancer risk values of deterministic risk assessment were close to the mean values predicted by the probabilistic risk assessment. The RME(reasonable maximum exposure) values fell within the range of 95% to 99.9% estimated by the probabilistic risk assessment. Since the values of carcinogenic risk assessment were higher than $10{\times}10^{-6}$, further detailed monitoring and refined risk assessment for benzene may be warranted to estimate more reliable and potential inhalation risks to receptors near the industrial complexes.