• Title/Summary/Keyword: property change

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Fabrication of Luminescent Hydroxyapatite Microspheres for Drug Loading and Release

  • Park, So Yeon;Kwon, Seung Lee;Baek, Mi Yeon;Yoo, Jin Sun;Kim, Min-Cheol;Jung, Hyun Suk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.360.1-360.1
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    • 2016
  • Hydroxyapatite (Ca10(PO4)6(OH)2, HAP) particles have attracted a great deal of attention in biomedical fields due to their good biocompatibility, bioactivity and fairly broad applications as drug delivery, dental implant, bone cement, and etc. Thus, many researchers have made an effort to add new functionalities such as luminescence, drug delivery, and bone regeneration properties up to HAP powders by controlling their nanostructure as well as composition. In this research, the mesoporous strontium substituted HAP (Sr-HAP) microspheres were synthesized using a hydrothermal method. In this synthesis, aspartic acid monomers were utilized to form microsphere by controlling surface energy of HAP particles and Sr ions were substituted into Ca ion sites, which induced luminescence property in HAP powders. Moreover, the change in the amount of Sr substitution was found to influence the particle size, morphology, and concurrently surface area, which led to changing drug loading as well as drug release property. The amount of Sr influences the morphology, luminescent properties, particle size, surface area cell viability and drug loading property, which are investigated by SEM, TEM, XRD, FTIR, BET, XPS and in vitro test such as MTT assay and drug release test. In particular, the multifunctional Sr-HAP with molar ratios of 0.25 (Sr/(Ca+Sr)) possessed the strongest luminescent property as well as the superior drug loading and sustained release properties that were correspondent with large surface area and pore size. Our study indicates that the fabricated multifunctional Sr-HAP microspheres are quite useful for bone regeneration and drug delivery.

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Statistical estimation of crop yields for the Midwestern United States using satellite images, climate datasets, and soil property maps

  • Kim, Nari;Cho, Jaeil;Hong, Sungwook;Ha, Kyung-Ja;Shibasaki, Ryosuke;Lee, Yang-Won
    • Korean Journal of Remote Sensing
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    • v.32 no.4
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    • pp.383-401
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    • 2016
  • In this paper, we described the statistical modeling of crop yields using satellite images, climatic datasets, soil property maps, and fertilizer data for the Midwestern United States during 2001-2012. Satellite images were obtained from the Moderate Resolution Imaging Spectroradiometer (MODIS), and climatic datasets were provided by the Parameter-elevation Regressions on Independent Slopes Model (PRISM) Climate Group. Soil property maps were derived from the Harmonized World Soil Database (HWSD). Our multivariate regression models produced quite good prediction accuracies, with differences of approximately 8-15% from the governmental statistics of corn and soybean yields. The unfavorable conditions of climate and vegetation in 2012 could have resulted in a decrease in yields according to the regression models, but the actual yields were greater than predicted. It can be interpreted that factors other than climate, vegetation, soil, and fertilizer may be involved in the negative biases. Also, we found that soybean yield was more affected by minimum temperature conditions while corn yield was more associated with photosynthetic activities. These two crops can have different potential impacts regarding climate change, and it is important to quantify the degree of the crop sensitivities to climatic variations to help adaptation by humans. Considering the yield decreases during the drought event, we can assume that climatic effect may be stronger than human adaptive capacity. Thus, further studies are demanded particularly by enhancing the data regarding human activities such as tillage, fertilization, irrigation, and comprehensive agricultural technologies.

Enzymatic Modification of Wool/Polyester Blend Fabrics Using Lipase from Aspergillus Oryzae (리파제에 의한 양모/폴리에스터 혼방직물의 동시 개질)

  • Song, Hyun-Joo;Kim, Hye-Rim;Song, Wha-Soon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.7
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    • pp.1121-1127
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    • 2009
  • This study presents an eco-friendly and one-step finishing method for modifying fiber property that reduces fiber damage in wool/polyester blend fabrics. Lipase from aspergillus oryzae is used in this experiment. The enzymatic treatment condition is optimized by measuring the relative activity of lipase depending on pH level, temperature, concentration of lipase, and treatment time. The concentration of $CaCl_2$as an activator is determined by the characteristics including whiteness, water contact angle (WCA), and dyeing property. The modified properties of lipase treated fabrics are tested for pill resistance and surface morphology. The results are described as follows: the optimum condions for lipase treatment constitute a pH level of 8.0, treatment temperature of 40$^{\circ}$$_C$, concentration of lipase at 100% (o.w.f), and a treatment time of 90 minutes. $CaCl_2$helps in raising lipase activation, and the optimum concentration is 50mM. The whiteness, wet ability, and pill resistance of lipase treated fabrics improves as compared to the control. The dyeing property of lipase treated fabrics improved by 53.5% after using the one-bath dyeing method. This means that lipase treatment can save time and cost during the dyeing process since lipase treatment modifies wool and polyester fibers. The surface of lipase treated wool fibers do not exhibit any change, however voids and cracks manifest on the surface of lipase treated polyester fibers.

ANALYSIS OF ELECTROWETTING DYNAMICS WITH LEVEL SET METHOD AND ASSESSMENT OF PROPERTY INTERPOLATION METHODS (레벨셋 기법을 이용한 전기습윤 현상의 동적 거동에 대한 해석 및 물성 보간 방법에 대한 고찰)

  • Park, J.K.;Kang, K.H.
    • 한국전산유체공학회:학술대회논문집
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    • 2010.05a
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    • pp.551-555
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    • 2010
  • Electrowetting is a versatile tool to handle tiny droplets and forms a backbone of digital microfluidics. Numerical analysis is necessary to fully understand the dynamics of electrowetting, especially in designing electrowetting-based devices, such as liquid lenses and reflective displays. We developed a numerical method to analyze the general contact-line problems, incorporating dynamic contact angle models. The method is based on the conservative level set method to capture the interface of two fluids without loss of mass. We applied the method to the analysis of spreading process of a sessile droplet for step input voltages and oscillation of the droplet for alternating input voltages in electrowetting. The result was compared with experimental data. It is shown that contact line friction significantly affects the contact line motion and the oscillation amplitude. The pinning process of contact line was well represented by including the hysteresis effect in the contact angle models. In level set method, in the mean time, material properties are made to change smoothly across an interface of two materials with different properties by introducing an interpolation or smoothing scheme. So far, the weighted arithmetic mean (WAM) method has been exclusively adopted in level set method, without complete assessment for its validity. We viscosity, thermal conductivity, electrical conductivity, and permittivity, can be an alternative. I.e., the WHM gives more accurate results than the WAM method in certain circumstances. The interpolation scheme should be selected considering various characteristics including type of property, ratio of property of two fluids, geometry of interface, and so on.

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Analysis of Unsteady Propagation of Mode III Crack in Arbitrary Direction in Functionally Graded Materials (함수구배재료에서 임의의 방향을 따라 비정상적으로 전파하는 모드 III 균열해석)

  • Lee, Kwang Ho;Cho, Sang Bong;Hawong, Jai Sug
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.2
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    • pp.143-156
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    • 2015
  • The stress and displacement fields at the crack tip were studied during the unsteady propagation of a mode III crack in a direction that was different from the property graduation direction in functionally graded materials (FGMs). The property graduation in FGMs was assumed based on the linearly varying shear modulus under a constant density and the exponentially varying shear modulus and density. To obtain the solution of the harmonic function, the general partial differential equation of the dynamic equilibrium equation was transformed into a Laplace equation. Based on the Laplace equation, the stress and displacement fields, which depended on the time rates of change in the crack tip speed and stress intensity factor, were obtained through an asymptotic analysis. Using the stress and displacement fields, the effects of the angled property variation on the stresses, displacements, and stress intensity factors are discussed.

NDR Property and Energy Band Diagram of Nitro-Benzene Molecule Using STM (STM에 의한 니트로벤젠 분자의 NDR 특성과 에너지 밴드 구조)

  • Lee, Nam-Suk;Chang, Jeong-Soo;Kwon, Young-Soo
    • Proceedings of the KIEE Conference
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    • 2005.11a
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    • pp.139-141
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    • 2005
  • It is possble to study charge transfer property which is caused by height variation because we can see the organic materials barrier height and STM tip by organic materials energy band gap. Here, we investigated the negative differential resistance(NDR) and charge transfer property of self-assembled 4,4-Di(ethynylphenyl)-2'-nitro-1-(thioacetyl)benzene, which has been well known as a conducting molecule. Self-assembly monolayers(SAMs) were prepared on Au(111), which had been thermally deposited onto pre-treatment($H_{2}SO_{4}:H_{2}O_{2}$=3:1) Si. The Au substrate was exposed to a 1 mM/l solution of 1-dodecanethiol in ethanol for 24 hours to form a monolayer. After thorough rinsing the sample, it was exposed to a $0.1{\mu}M/1$ solution of 4,4-Di(ethynylphenyl)-2'-nitro-1-(thioacetyl)benzene in dimethylformamide(DMF) for 30 min and kept in the dark during immersion to avoid photo-oxidation. After the assembly, the samples were removed from the solutions, rinsed thoroughly with methanol, acetone, and $CH_{2}Cl_{2}$, and finally blown dry with $N_2$. Under these conditions, we measured electrical properties of self-assembly monolayers(SAMs) using ultra high vacuum scanning tunneling microscopy(UHV-STM). The applied voltages were from -1.50 V to -1.20 V with 298 K temperature. The vacuum condition is $6{\times}10^{-8}$ Torr. As a result, we found that NDR and charge transfer property by a little change of height when the voltage is applied between STM tip and electrode.

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Economic Valuation for The Available land in National and Public General Property (국.공유 일반재산 중 가용토지의 경제적 가치평가 - 칠곡군을 중심으로 -)

  • Lee, Ji-Soo;Lee, Seung-Wook;Hong, Won-Hwa
    • Spatial Information Research
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    • v.19 no.1
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    • pp.41-50
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    • 2011
  • In Chilgok, industrial complex and agro-industrial complex has facilitated with the population growth rate of 2.79% since 1995. And the city should be apparently required more additional land for agriculture and industrial complex due to the demands of developments. However, many experts has pointed out that utilization of national and public property might be declined recently because the property management office owns too many unnecessary idle lands. So the city is being faced with the necessity of establishing an efficient system for the management of available lands. Therefore, this study evaluated the economic value of available national and public land in Chilgok city. Rental or sale of economic value by separating the target has been also assessed. As a result, each town has totally different characteristics of available lands and the economic values and the numerical change of economic values can measure when merge lots.

Study on the thermal Property and Aging Prediction for Pressable Plastic Bonded Explosives through ARC(Heat-Wait-Search method) & isothermal conditions (ARC(Heat-Wait-Search method)와 isothermal 조건을 이용한 압축형 복합화약의 열적 특성 및 노화 예측 연구)

  • Lee, Sojung;Kim, Jinseuk;Kim, Seunghee;Kwon, Kuktae;Chu, Chorong;Jeon, Yeongjin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2017.05a
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    • pp.172-178
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    • 2017
  • Thermal property is one of the important characteristic in the field of energetic materials. As the energy material is released during decomposition, DSC(Differential Scanning Calorimetry) is frequently used for the thermal analysis. In case of the dynamic DSC measurements, thermal dynamic change like melting is prevented from the thermal property measurements. And due to the predicting kg scale, the conditions of the heat exchange with the environment significantly is changed. In this study, As the method to resolve the problem, we predict the thermal aging property using the AKTS thermokinetic program from DSC measurements which performed isothermal method. Predicting the thermal aging properties from ARC(Accelerating Rate Calorimetry) measurement, we compare two results.

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Physical and Hand Properties of the Knitted Fabrics From Machine Knitting Fancy Yarns (기계편용 장식사 니트소재의 물성 및 감성 평가)

  • Park, Key-Yoon;Park, Myung-Ja
    • Journal of the Korea Fashion and Costume Design Association
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    • v.10 no.2
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    • pp.125-138
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    • 2008
  • For physical and hand property evaluation of fabrics, the knitted fabrics from 11 types of machines knitting fancy yarns, boucle (M1), knot (M2), snarl (M3), and slub (M4), tamtam (M5), tubular (M6), fur 1 (M7), bead (M8), fur 2 (M9), fur 3 (M10), and ladder (M11) yarns, were prepared with 7-10 G plain stitch. Washing test and pilling test had also been carried out. For hand properties by objective sensibility evaluation, 17 items of sir mechanical properties using KES-FB (Kawabata Evaluation System) had been measured. Then hand values of knitted fabrics were calculated with a calculation formula, namely KN-402-KT. Finally the total hand values were obtained through KN-301-WINTER. As a result of physical properties and objective evaluation for machines knitting fancy fabrics, most of them shrank in the direction of wale and course after the washing test, in which their shrinkage rate had a maximum of 3.5%. Therefore, the washing test indicated that the shrinkage ratio of knitted fabrics had a minor change. The results of the pilling test are mostly 4-5th grade, and all of the machines knitting fancy fabrics showed good results in the pilling resistance. In hand properties and objective sensibility evaluation, twisted fancy yarns, such as boucle (M1), knot (M2), snarl (M3), and slub (M4), were superior to bonding rigidity (B) and shear rigidity (G). The surface property between course and wale differs in all samples and course direction is tougher than wale direction. FUKURAMI (fullness and softness) of all samples have high values, besides NUMERI (smoothness) of tamtam (M5) and boucle (M1), which were rather good. Most samples except fur 1 (M7) had low KOSHI (stiffness) value. The total hand value (THV) of twisted yarns was low. This study proves that manufacturers, who plan knitting yarn products and knit fashion, can apply these data to develop machines knitting yarns and knits that fit the consumers' demands.

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A Study on the Property and Performance Characteristics of Different Kind Engine Oil by Endurance Test of Heavy-duty Diesel Engine (대형 디젤엔진 내구 시험에 의한 다른 종류 엔진오일의 물성 및 성능 특성에 관한 연구)

  • Lee, Minho;Kim, Jeonghwan;Song, Hoyoung;Kim, Giho;Ha, Jonghan
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.7
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    • pp.48-56
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    • 2014
  • Engine oil is an oil used for lubrication of various internal combustion engines. The main function is to reduce wear on moving parts; it also cleans, inhibits corrosion, improves sealing, and cools the engine by carrying heat away from moving parts. In engines, there are parts which move against each other. Otherwise, the friction wastes the useful power by converting the kinetic energy to heat. Those parts were worn away, which could lead to lower efficiency and degradation of the engine. It increases fuel consumption, decreases power output, and can induce the engine failure. This study was conducted to evaluate the relation between engine oil property changes and engine performance for the diesel engine. This test was performed by using 12L, 6 cylinder, heavy duty engines. Low SAPS 10W30 engine oil (two type engine oils) was used. Test procedure and method was in accordance with the modified CEC L-57-T97 (OM441LA) method. In this study, TAN, TBN, KV and metal components, engine power, blowby gas, A_F were presented to evaluate the relation with engine oil property changes and engine performance. TAN, TBN, KV and metal We found that the components were generally increased but engine performance did not change. This results mean that property changes did not affect on engine performance because those were not enough to affect engine performance.