• Journal of Pharmaceutical Investigation
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• v.39 no.1
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• pp.43-49
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• 2009

Aspirin or acetylsalicylic acid, a member of the salicylate family, is frequently used as an analgesic, antipyretic, anti-inflammatory and antiplatelet drug. Because aspirin is chemically unstable in water and heat for tablet formulation, additives including lubricants are used in preparing aspirin tablets, using a dry-granulation process. Aspirin tablets are produced by a number of manufacturers which usually use their own unique combination of additives during the manufacturing process. In this study, we employed an NMR based metabolomics technique to identify the manufacturers of various aspirin tablets. Aspirin tablets from six different companies were analyzed by 1H 400 MHz NMR. The acquired data was then integrated and processed by principal component analysis (PCA). Based on the NMR data, we were able to identify peaks corresponding to acetylsalicylic acid in all of the six samples, whereas different NMR patterns were found in the aromatic and aliphatic regions depending on the unique additive used. These observations led to the conclusion that the differences in the NMR patterns among the different aspirin tablets were due to the presence of additives.

• Korean Institute of Interior Design Journal
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• v.19 no.5
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• pp.48-55
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• 2010

Marcel Wanders, one of the greatest designers in the world of contemporary design, was born in the Netherlands. His works run the gamut from interior design to furniture design to lighting design, building a unique world of works. He started to gain fame when he presented "Knotted Chair" at Droog Design in 1996, which was made out of aramid ropes and later became his symbol. In 2000, he established "moooi," a world-renowned design label. By giving characteristic qualities, his works are given meaning, and like a fantastical dream, their images are extremely fantastical and stimulating. As can be seen in his character cover, he puts emphasis on the harmony between minimalism and decoration, establishing his own unique design concept. In this thesis, based on Marcel Wander's design philosophy, his overall design characteristics were classified into theatrical effects and storytelling. Expressive elements depaysement, eclectic mixture, and scale modification were derived from theatrical effects and analyzed; for storytelling, object, semantic cues, and dream and fantasy were derived and analyzed. A distinguishing feature of such analysis is his meaning-centric design approach, the principle by which to form long-term relationships with the users by creating user-centric designs that make them find meaning and values in diverse experiences in their daily routine, giving them familiar yet unique experience.

• Health Policy and Management
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• v.30 no.3
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• pp.376-385
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• 2020

Background: The purpose of this study is to investigate the factors affecting the healthy living practice rate such as non-smoking, moderate drinking, walking, and low-salt diet by elementary municipality (so called, 'si-gun-hu'). Methods: The 2016 Korean Community Health Survey was used for the analysis. The theoretical model is founded upon the Anderson model, and both the multiple linear regression analysis and the beta regression analysis was performed for estimation. Results: As a result of the beta regression analysis, healthy living practice rate was found to be significantly higher in the areas with a less number of cigarette retailers, participating in healthy city projects, a low proportion of people who perceive their body type as obesity, a higher proportion of women, and a lower proportion of spouses. Conclusion: In order to improve healthy living practices, the regulations on health risk businesses, the spread of Healthy City project, and policy efforts awaring obesity are recommended.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.17 no.4
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• pp.389-403
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• 2019

Large amounts of concrete waste are likely to arise from the decommissioning of a Kori-1 nuclear power plant. Several studies have been conducted on decommissioning concrete waste in recent decades, however, they have been limited to contaminated concrete issues or were small pilot-scale experiments. This study constructed two industrial-scale models of on-site concrete waste management for clean as well as contaminated concrete. To evaluate the performance of both the models, simulations were conducted using the Flexsim software. The concrete particle size distribution of Kori-1 and concrete processor properties based on widely used construction equipment were used as sources of input data for the simulations. It was observed that it may take over two years to complete the on-site concrete management processes owing to the performance of existing processors. In addition, it was demonstrated that it is essential to identify bottlenecks in the system and enhance the performance of the relevant processors to avoid delays of the decommissioning schedule. Our results suggest that this novel approach can contribute to developing schedules or expediting delayed activities in the Kori-1 decommissioning project.

• Journal of the Korean Society of Systems Engineering
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• v.12 no.2
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• pp.1-8
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• 2016

The system engineering should be actively applied to successfully develop a complex and advanced weapon system, because the system engineering uses a multidisciplinary approach. Therefore, this study proposed a system engineering process for a successful weapon system development. According to the national standard policy, an IPT aspect system engineering standard must adapt the ISO/IEC/IEEE 15288. It also asks for tailoring with considering the IPT characteristics as a weapon system acquisition institution. The IPT aspect system engineering process to acquire a weapon system can be expressed with 3 process groups (Agreement, Technical Management, Technical) and 20 processes. There was a need for an institutional framework to hire retired experts from related organizations as consultants to apply the low-cost and high efficiency system engineering in the weapon system acquisition field.

• Journal of Korea Technology Innovation Society
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• v.16 no.1
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• pp.176-198
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• 2013

Preliminary feasibility study(PFS) was introduced in 1999 by financial authority to encourage a cautious approach to new large-scale public investment project. As it applied cost-benefit analysis as prime measure for decision-making, various issues have been arisen concerning feasibility analysis on R&D programs. This work is intended to suggest standard approaches to be established in PFS on R&D program as follows: 1. The issue questions can be induced in a standard way by 15 representative questions and their correlation with evaluation criteria. 2. The analyzing strategy can be standardized by establishing standards for classification of R&D effects and R&D logic analysis.

• Journal of the Korean Society of Systems Engineering
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• v.10 no.1
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• pp.33-41
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• 2014

New design concept of Reactor Coolant System (RCS) including a reactor assembly for the SMR is introduced in this work. An exploration of new type of reactor that is advanced from proposed SMRs is performed by using systems engineering approach. In this point of view project structured on three main phases; needs analysis (NA), concept exploration (CE), and concept definition (CD). Main objectives as an output of the CE stage are a small size, low cost, shortening the schedule, and enhancing safety. The SMRs usually have a small size requirement. In order to meet the size requirement and to achieve a productivity, in other words, easiness to manufacture, this paper suggests an integrated PWR design concept through researching predecessors. Although the integrated PWR concept provides many advantages, it has disadvantages that composite of maintenance and a low availability problem. Therefore, this paper comes up with a run-to-fail design concept based on modular design to address the maintenance problem and to maximize the availability of SMRs as well as to be compatible with the overall-SMRs including Barge Mounted(BM)type.

• Journal of the Korean Society of Systems Engineering
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• v.10 no.2
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• pp.59-69
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• 2014

In the bidding stage of turn-key based plant construction contracts, owners provide design and performance basis for contractors instead of giving design drawing. To win the bid for a plant construction, the contractors should be obliged to satisfy and ensure owners'requirements such as design and performance basis in a plant construction project, In other words, owners imposes technical risk of the design to the contractors by specifying responsibility for the analysis and verification of the plant construction. Thus, it is very important that contracters make accurate and realistic basic design plan in a short period of time. To deal with such a situation, we propose a systems engineering approach for the analysis and management of the technical risk. Specifically, we first: 1) Analyzes technical risk related with the plant design information for the bidders, followed by 2) Developing stakeholder requirements for the basic engineering design, and 3) System requirements for dealing with technical risk. Also, in this paper, we proposed converting method from MOE(Measure of Effectiveness) to MOP(Measure of Performance) in the risk analysis. To show the effectiveness of the proposed method, we carried out a case study.

• Journal of Advanced Navigation Technology
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• v.21 no.6
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• pp.549-553
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• 2017

The KASS development project, a Korean SBAS launched in 2014, is under development for the APV-1 Class SOL service in 2022. Flight tests should be conducted to analyze development requirements and performance requirements for KASS R & D. However, since the evaluation items have not yet been presented in Korea, FAA and ICAO regulations should be analyzed so that evaluation items for flight testing for KASS development should be structured and comply with international standards. In this paper, we analyze the procedure verification of SBAS for flight test using satellite navigation system.

• Journal of the Korean Society of Systems Engineering
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• v.9 no.2
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• pp.37-53
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• 2013

With rapid growth of the world plant market, an increasing attention is paid on the plant engineering. Up to present time, Korean plant engineering technology has been concerned with the down stream part of the plant engineering, so called EPC, considered as a lower value chain compared with the up stream, composed of FEED(Front End Engineering Design) and PMC(Project Management Consultancy). In other words, a key issue for Korean plant industry is how to catch up the FEED technology, currently occupied by the advanced countries. In this paper, we propose an SE(Systems Engineering) approach, conventionally applied for aerospace and defense industry, to the FEED for plant engineering. Specifically, we proposed a new SE process composed of: 1) SPA matrix for reverse systems engineering, and 2) PPA matrix for forward systems engineering. To illustrate the proposed method, a case study for an environmental plant is performed.