• Title/Summary/Keyword: prognosis

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A Study on Feasibility Evaluation for Prognosis Systems based on an Empirical Model in Nuclear Power Plants

  • Lee, Soo Ill
    • International Journal of Safety
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    • v.11 no.1
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    • pp.26-32
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    • 2012
  • This paper introduces a feasibility evaluation method for prognosis systems based on an empirical model in nuclear power plants. By exploiting the dynamical signature characterized by abnormal phenomena, the prognosis technique can be applied to detect the plant abnormal states prior to an unexpected plant trip. Early $operator^{\circ}{\emptyset}s$ awareness can extend available time for operation action; therefore, unexpected plant trip and time-consuming maintenance can be reduced. For the practical application in nuclear power plant, it is important not only to enhance the advantages of prognosis systems, but also to quantify the negative impact in prognosis, e.g., uncertainty. In order to apply these prognosis systems to real nuclear power plants, it is necessary to conduct a feasibility evaluation; the evaluation consists of 4 steps (: the development of an evaluation method, the development of selection criteria for the abnormal state, acquisition and signal processing, and an evaluation experiment). In this paper, we introduce the feasibility evaluation method and propose further study points for applying prognosis systems from KHNP's experiences in testing some prognosis technologies available in the market.

Live birth outcomes of vitrified embryos generated under growth hormone stimulation are improved for women categorized as poor-prognosis

  • Keane, Kevin N;Ye, Yun;Hinchliffe, Peter M;Regan, Sheena LP;Dhaliwal, Satvinder S;Yovich, John L
    • Clinical and Experimental Reproductive Medicine
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    • v.46 no.4
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    • pp.178-188
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    • 2019
  • Objective: To determine the clinical pregnancy (CP) and live birth (LB) rates arising from frozen embryo transfers (FETs) that had been generated under the influence of in vitro fertilization (IVF) adjuvants given to women categorized as poor-prognosis. Methods: A registered, single-center, retrospective study. A total of 1,119 patients with first FETs cycle include 310 patients with poor prognosis (109 treated with growth hormone [GH], (+)GH group vs. 201 treated with dehydroepiandrosterone, (-)GH group) and 809 patients with good prognosis (as control, (-)Adj (Good) group). Results: The poor-prognosis women were significantly older, with a lower ovarian reserve than the (-)Adj (Good) group, and demonstrated lower chances of CP (p< 0.005) and LB (p< 0.005). After adjusting for confounders, the chances of both CP and LB in the (+)GH group were not significantly different from those in the (-)Adj (Good) group, indicating that the poor-prognosis patients given GH had similar outcomes to those with a good prognosis. Furthermore, the likelihood of LB was significantly higher for poor-prognosis women given GH than for those who did not receive GH (p< 0.028). This was further confirmed in age-matched analyses. Conclusion: The embryos cryopreserved from fresh IVF cycles in which adjuvant GH had been administered to women classified as poor-prognosis showed a significant 2.7-fold higher LB rate in subsequent FET cycles than a matched poor-prognosis group. The women with a poor prognosis who were treated with GH had LB outcomes equivalent to those with a good prognosis. We therefore postulate that GH improves some aspect of oocyte quality that confers improved competency for implantation.

FACTORS AFFECTING 6 MONTHS' SHORT-TERM PROGNOSIS OF CONDUCT DISORDER IN THE ADOLESCENTS II -RELATION TO DEPRESSION/ANXIETY AND ADHD INVENTORY- (청소년 품행장애의 6개월 단기 예후에 영향을 미치는 변인 II - 우울 및 불안척도와 주의력결핍 과잉활동 척도를 중심으로 -)

  • Bang, Yang-Won;Chae, Jeong-Ho;Chin, Tae-Won;Lee, Chung-Kyoon
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.2
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    • pp.161-166
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    • 1996
  • The major goals of this study are to investigate the correlation between the cormorbid symptom and the prognosis of conduct disorder in the adolescents. for this purpose, according to the result of 6-month follow-up of discharged patient who met the criteria of conduct disorder in admission, good-prognosis group(n=37) and poor-prognosis group(n=36) were selected. Authors applied Children's Depression Inventory and Trait Anxiety Inventory, Conners Parenting Rating Scale. Yale Children's Inventory to two groups. The results are summarized as follows : 1) Using CDI, the mean scores of poor-prognosis group were significantly higher compared with those of good prognosis group. 2) Using TAI, CPRS, YCI, the mean scores of poor-prognosis group were insignificantly higher compared with those of good prognosis. 3) The limitation of our study is that number of subjects is small, definition of prognosis is ambiguous, and period of 6 month follow-up is short.

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Iranian Cancer Patient Perceptions of Prognosis and the Relationship to Hope

  • Seyedrasooli, Alehe;Rahmani, Azad;Howard, Fuchsia;Zamanzadeh, Vahid;Mohammadpoorasl, Asghar;Aliashrafi, Raha;Pakpour, Vahid
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6205-6210
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    • 2014
  • Background: The aim of this study was to investigate Iranian cancer patient perceptions of their prognosis, factors that influence perceptions of prognosis and the effect this has on patient level of hope. Materials and Methods: Iranian cancer patients (n=200) completed self-report measures of their perceptions of their prognosis and level of hope, in order to assess the relationship between the two and identify factors predictive of perceptions by multiple linear regression analysis. Results: Cancer patients perceived of their prognosis positively (mean 11.4 out of 15), believed their disease to be curable, and reported high levels of hope (mean 40.4 out of 48.0). Multiple linear regression analyses demonstrated that participants who were younger, perceived they had greater family support, and had higher levels of hope reported more positive perceptions of their cancer prognosis. Conclusions: Positive perceptions of prognosis and its positive correlation with hope in Iranian cancer patients highlights the importance of cultural issues in the disclosure of cancer related information.

High-grade mucoepidermoid carcinoma in the thyroid gland with poor prognosis

  • Shin, Hyeong Chan
    • Journal of Yeungnam Medical Science
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    • v.38 no.2
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    • pp.169-174
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    • 2021
  • Mucoepidermoid carcinoma (MEC) is the most common malignant neoplasm of the salivary gland, but primary thyroid MEC has rarely been reported and usually has a good prognosis. Herein, I report a case of thyroidal MEC with a poor prognosis in an 82-year-old woman with an anterior neck mass. Ultrasonography and computed tomography revealed a thyroid mass. The patient initially underwent fine-needle aspiration, was diagnosed with malignancy, and underwent a right lobectomy. On gross examination, a 4.0×3.6×2.6 cm-sized ill-defined, unencapsulated, and infiltrative tan to whitish mass with necrosis was identified. Microscopically, epidermoid tumor cell nests or solid sheets were identified. Mucous cells that were positive for periodic acid-Schiff and mucicarmine stains were also identified within epidermoid cell nests. Frequent mitosis and necrosis were observed. Immunohistochemical staining for p40 and p63 was positive, and that for thyroid transcription factor-1 and paired box gene 8 was focally positive. According to the Armed Forces Institute of Pathology grading system for salivary gland MEC, the current case was classified as high-grade MEC. After surgery, the patient suffered from dyspnea due to a remnant neck mass that compressed and obstructed the trachea; therefore, the patient refused further treatment. Thyroidal MECs are considered low-grade with a favorable prognosis, but there are several reported cases of thyroidal MEC with poor prognosis. The current case is a rare presentation of high-grade thyroidal MEC with a poor prognosis.

Machine Fault Diagnosis and Prognosis: The State of The Art

  • Tung, Tran Van;Yang, Bo-Suk
    • International Journal of Fluid Machinery and Systems
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    • v.2 no.1
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    • pp.61-71
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    • 2009
  • Machine fault diagnostic and prognostic techniques have been the considerable subjects of condition-based maintenance system in the recent time due to the potential advantages that could be gained from reducing downtime, decreasing maintenance costs, and increasing machine availability. For the past few years, research on machine fault diagnosis and prognosis has been developing rapidly. These publications covered in the wide range of statistical approaches to model-based approaches. With the aim of synthesizing and providing the information of these researches for researcher's community, this paper attempts to summarize and classify the recent published techniques in diagnosis and prognosis of rotating machinery. Furthermore, it also discusses the opportunities as well as the challenges for conducting advance research in the field of machine prognosis.

Analysis of Prognosis Graphs in Korean Medicine (그래프 기반 한의 예후 분석 - 팔강육음, 기혈진액, 장부 변증을 중심으로 -)

  • Kim, Sang-Kyun;Kim, An Na
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.6
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    • pp.818-822
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    • 2012
  • We in this paper propose a prognosis graph, analyzing prognoses of each pattern described in the Korean medicine literatures. This graph is represented as the integrated graphs about knowledge of patterns and their transitions in the prognoses, where a node becomes a pattern name and a edge becomes a transition between patterns, along with a condition with respect to cause or mechanism of the pattern. The knowledge of prognoses which a pattern is transit into another pattern can be identified at a glance by using this model. We also construct a upper-level prognosis graph, excluding five viscera and six entrails from the model. This upper-level prognosis graph contains the conceptual knowledge than clinical one so that it may be helpful to students and researchers in the Korean medicine fields.

On-line Motion Planner for Multi-Agents based on Real-Time Collision Prognosis

  • Ji, Sang-Hoon;Kim, Ji-Min;Lee, Beom-Hee
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.74-79
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    • 2005
  • In this paper, we propose a novel approach to decentralized motion planning and conflict-resolution for multiple mobile agents working in an environment with unexpected moving obstacles. Our proposed motion planner has two characteristics. One is a real-time collision prognosis based on modified collision map. Collision map is a famous centralized motion planner with low computation load, and the collision prognosis hands over these characteristics. And the collision prognosis is based on current robots status, maximum robot speeds, maximum robot accelerations, and path information produced from off-line path planning procedure, so it is applicable to motion planner for multiple agents in a dynamic environment. The other characteristic is that motion controller architecture is based on potential field method, which is capable of integrating robot guidance to the goals with collision avoidance. For the architecture, we define virtual obstacles making delay time for collision avoidance from the real-time collision prognosis. Finally the results obtained from realistic simulation of a multi-robot environment with unknown moving obstacles demonstrate safety and efficiency of the proposed method.

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Clinical and Pathological Factors Related to the Prognosis of Chinese Patients with Stage Ⅰb To Ⅱb Cervical Cancer

  • Xie, Xiu-Zhen;Song, Kun;Cui, Baoxia;Jiang, Jie;Zhang, You-Zhong;Wang, Bo;Yang, Xing-Sheng;Kong, Bei-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5505-5510
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    • 2012
  • Objective: The aim of this retrospective study is to analyze the clinical and pathological factors related to the prognosis of Chinese patients with stage Ib to IIb cervical cancer. Methods and Results: 13 clinical pathological factors in 255 patients with stage Ib to IIb cervical cancer undergoing radical hysterectomy and systematic lymphadenectomy were analyzed to screen for factors related to prognosis. The cumulative 5-year survival of the 255 patients was 75.7%. The result of the univariate analysis suggested that clinical stage, cell differentiation, depth of cervical stromal invasion, parametrial tissue involvement, and lymph node metastasis were prognostic factors for patients with stage Ib to IIb cervical cancer (P<0.05). Compared with cases with involvement of iliac nodes, obturator nodes, or inguinal lymph nodes, cases with metastasis to the common iliac lymph nodes had a poorer prognosis (P<0.05). Cases with involvement of four or more lymph nodes had a poorer prognosis than those with involvement of three or fewer lymph nodes (P<0.05). Using multivariate Cox proportional hazards model regression analysis, non-squamous histological type, poor differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion were found to be independently related to patients poor prognosis (P<0.05). Conclusion: Non-squamous histological type, poor cell differentiation, parametrial tissue involvement, and outer 1/3 stromal invasion are the independent poor prognostic factors for patients with stage Ib to IIb cervical cancer.

The Younger Patients Have More Better Prognosis in Limited Disease Small Cell Lung Cancer

  • Kim, Hye-Jin;Choi, Chang-Min;Kim, Seul-Gi
    • Tuberculosis and Respiratory Diseases
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    • v.79 no.4
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    • pp.274-281
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    • 2016
  • Background: Factors associated with the prognosis of patients with small cell lung cancer (SCLC) is relatively unknown, than of those with non-small cell lung cancer. This study was undertaken to identify the prognostic factors of SCLC. Methods: The medical records of 333 patients diagnosed with SCLC at tertiary hospital from January 1, 2008, to December 31, 2012 were retrospectively reviewed. Patients were categorized by age (${\leq}65$ years vs. >65 years) and by extent of disease (limited disease [LD] vs extensive disease [ED]). Overall survival and progression free survival rates were determined. Factors associated with prognosis were calculated using Cox's proportional hazard regression model. Results: Most baseline characteristics were similar in the LD and ED groups. Eastern Cooperative Oncology Group (ECOG) performance status (PS), first chemotherapy regimen, and prophylactic cranial irradiation (PCI) differed significantly in patients with LD and ED. Mean ECOG PS was significantly lower (p<0.001), first-line chemotherapy with etoposide-cisplatin was more frequent than with etoposide-carboplatin (p<0.001), and PCI was performed more frequently (p=0.019) in LD-SCLC than in ED-SCLC. Prognosis in the LD group was better in younger (${\leq}65$ years) than in older (>65 years) patients, but prognosis in the ED group was unrelated to age. Conclusion: This study showed that overall survival (OS) was significantly improved in younger than in older patients with LD-SCLC. Univariate and multivariate analyses showed that age, PCI and the sum of cycles were significant predictors of OS in patients with LD-SCLC. However, prognosis in the ED group was unrelated to age.