• 구강회복응용과학지
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• 제29권4호
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• pp.347-358
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• 2013

측모의 연조직 분석 시 Subnasale는 중요한 기준점으로 사용되지만 이상적인 위치에 대한 평가한 연구는 드물다. 본 연구의 목적은 한국인 측모에서 Subnasale의 위치 변화에 따른 심미적 안모에 대한 객관적 기준을 제시 하는 것이며, 추가적으로 전문가 집단과 일반 대중 간의 안모 선호도 인식에 어떤 차이가 존재하는지 평가 하는 것이다. 이번 연구를 위해 채득한 20대 여성 사진 중에서 전문가에 의해 결정된 적절한 측면 안모 비율로 판단되는 1명의 측모 사진을 선정하였다. 선정된 사진은 비순각을 유지하며 진성 수직선에 수직한 평면상에서 Subnasale을 전, 후방으로 변화시켰다. 합성된 사진은 전문가 집단(교정의사 9명)과 일반 대중(126명)에게 제시되어 각각의 선호도를 VAS상에 표시하도록 하였다. 다음의 결론을 얻었다. 1. Subnasale의 이상적인 위치는 Lateral canthus~Subnasale : Subnasale~Pronasale가 1.769 : 1을 이룰 때 이다. 2. 각도상 Nasion을 통과하는 진성 수직선과 Subnasale가 $5.5^{\circ}$를 이룰 때 이다. 3. 전문가 집단은 모든 비율 변화를 인지하였으나, 일반 대중은 1.571 : 1과 1.769 : 1 사이의 변화를 인지하지 못하였다.

• 대한방사선기술학회지:방사선기술과학
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• 제41권5호
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• pp.463-469
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• 2018

Morphological information such as shape and margin of micro lesion is important information for diagnosis of disease in clinical imaging. In this study, we investigated the morphological changes of the micro lesions by comparing the contrast and area in grid suppressed DR images according to grid frequency. In the profile analysis of the image, the mass showed an average intensity variation of 8.6 ~ 72.4 after suppression, The higher the grid frequency, the more the contrast was increased. However, in the images obtained using 103 lp / inch, which is a grid frequency less than the sampling frequency, the contrast of the mass in the vertical direction decreased after suppression. In the binary image, the area change of the mass was also large. As a result, the shape, size, and margin of the mass changed. In the case of very small calcification, the higher the grid frequency is the larger the change in contrast, so that a clear image can be obtained in the post-suppression image. However, we could confirm that the margin of the lesion was blurred and the lesion was lost in some of the images using the 103 lp / inch grid. The higher the frequency of the grid, The change of the contrast of fiber occurred largely and clear boundary was confirmed. The decrease of the number of pixels was small and morphological change was small. In conclusion, when using a grid frequency that is not suitable for the sample frequency, morphological changes or lesion loss of micro lesions in the post- suppression image may give the possibility of misdiagnosis in diagnosis and differentiation of the image.

• Journal of Acupuncture Research
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• 제24권1호
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• pp.151-163
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• 2007

Objectives : Juglandis Semen herbal acupuncture solution(JSS) has a broad array of clinical applications in oriental medicine, including treatment of chronic musculoskeletal diseases such as arthritis. This study was performed to investigate the global gene expression profiles using microarray assay in RAW 264.7 cell line treated with JSS and to advance our understanding of the pharmacologic effect of JSS. Methods : Change of the gene expression profile in RAW cell line following treatment with lipopolysaccharide(LPS) alone, or with LPS plus JSS was investigated with a cut-off level of 2 fold change in the expression. Especially, Change of the gene expression by treatment with LPS alone was compared with that by treatment with LPS plus JSS with a cut-off level of 1/2 fold change in the expression. Results: Of the 8170 genes profiled in this study, 51 were upragulated and 21 downregulated following LPS treatment, and 88 were upregulated and 69 downregulated following costimulation of JSS and LPS. Of the 51 genes upregulated following LPS treatment, 10 were downregulated following costimulation of JSS and LPS. Of the 21 genes downregulated following LPS treatment, 3 were upregulated following costimulation of JSS and LPS. Conclusion : JSS treatment induced upregulation of some genes including IL-10 and downregulation of that including MMP13 with its possible implication in an antiinflammatory action of JSS. However, further research on expression profile changes induced by JSS treatment is expected.

• 터널과지하공간
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• 제23권5호
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• pp.401-412
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• 2013

전단거동에 의한 절리면의 거칠기 변화가 전단강도에 미치는 영향을 조사하기 위하여 절리면 강도가 상이한 편마암, 화강암 및 셰일 시료를 이용하여 순차적 다단계 전단시험을 수행하였다. 시험단계별로 절리면 프로파일의 고도를 측정하여 거칠기 계수를 산정하고 미세 거칠기 빈도 변화를 조사하였다. 거칠기 감쇠에 대한 최적의 거칠기 계수를 산정하여 반복된 전단거동에 의한 순차적 거칠기 감쇠특성을 고찰하였다. 전단강도식을 산정하여 점착력과 마찰각의 차별적 변화양상을 도출하였으며, 표면 거칠기의 마모, 파쇄 및 재형성에 의한 미세 거칠기 빈도변화를 조사하여 강도계수 변화의 원인적 요인을 분석하였다. 또한, 미세 거칠기 변화양상이 전단강도에 미치는 영향을 절리면 강도를 고려하여 분석하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제31권3호
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• pp.274-278
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• 2005

Purpose : Prediction for soft tissue change after orthognathic surgery is very important for the final esthetics. In this study, we have tried to get the amount of upper lip movement relative to bony segment movement after anterior segmental osteotomy by cephalmetric analysis to predict final upper lip position after surgery. Material and Methods : 20 patients was studied on whom anterior segmental osteotmy as performed by Cupar method during the years 2002 to 2003. Cephalometric radiograph were taken at 1month before surgery and 6 month after surgery. Change of upper lip was measured on landmark Ls and Sto relative to hard tissue (landmark Ia) setback on these X-rays and analyzed. Results : 1. Upper lip setback movement. Setback of upper lip showed proportional relation to the hard tissue setback and the ratio was about 84%(p=0.001). 2. Upper lip downward movement. Downward movement of upper lip showed no proportional relation to hard tissue setback And the amount was mean 1.38 mm and SD 1.21mm (p=0.922). Conclusion : The posterior movement of upper lip is affected by hard tissue movement and shows good proportional change whereas downward movement is not so much influenced by hard tissue movement. And we think slight downward movement shown in this study could be explained by the V-Y closure performed during surgery.

• Journal of Acupuncture Research
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• 제23권4호
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• pp.135-148
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• 2006

Objectives : Juglandis Semen herbal acupuncture solution(JSS) has a broad array of clinical applications in oriental medicine, including treatment of chronic musculoskeletal diseases such as arthritis. This study was performed to investigate the global gene expression profiles using microarray assay in RAW 264.7 cell line treated with JSS and to advance our understanding of the pharmacologic effect of Jss. Methods : Change of the gene expression profile in RAW cell line following treatment with JSS alone, with lipopolysaccharide(LPS) alone, or with LPS plus JSS was investigated with a cut-off level of 2 fold change in the expression. Results : Of the 8170 genes profiled in this study, 95 were upragulated and 42 downregulated following JSS treatment, 51 were upragulated and 21 downregulated following LPS treatment, and 88 were upregulated and 69 downregulated following costimulation of JSS and LPS. Conclusion : JSS treatment induced upregulation of some genes including IL-10 with its possible implication in an antiinflammatory action of JSS. However, further research on expression profile changes induced by JSS treatment is expected.

• Asian Journal of Atmospheric Environment
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• 제9권1호
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• pp.22-30
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• 2015

This study evaluated road shape and roadside barrier impact on near-road air pollution dispersion using FLUENT computational fluid dynamics (CFD) model. Simulated road shapes are three types, namely at-grade, depressed, and filled road. The realizable k-${\varepsilon}$ model in FLUENT CFD code was used to simulate the flow and dispersion around road. The selected concentration profile results were compared with the wind tunnel experiments. The overall concentration profile results show good agreement with the wind tunnel results. The results showed that noise barriers, which positioned around the at-grade road, decrease the horizontal impact distance (In this study, the impact distance was defined as the distance from road surface origin coordinate to the position whose mass fraction is 0.1.) lower 0.33~0.65 times and change the vertical air pollution impact distance larger 2.0~2.27 times than those of no barrier case. In case of filled road, noise barriers decrease the horizontal impact distance lower 0.24~0.65 times and change the vertical air pollution impact distance larger 3.33~3.55 times than those of no barrier case. The depressed road increase 1.53~1.68 times the vertical air pollution impact distance. It contributes the decrease of horizontal air pollution impact distance 0.32~0.60 times compare with no barrier case.

• Asian-Australasian Journal of Animal Sciences
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• 제13권8호
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• pp.1050-1053
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• 2000

Biological evaluation of residual malathion after 168 hrs of single dipping exposure of White Leghorn hens to different concentrations (0, 0.5, 1.0 and 1.5%) of pesticides was investigated. Thirty-two male albino rats divided into four groups of eight each were kept on 20% isoproteinous diet prepared from the meat of these malathion dipped hens. After 30 days feeding trial, the rats were killed by decapitation. No significant change was found in erythrocytes. However, the triglyceride concentration in brain tissue was increased significantly (p<0.05) when dose level of pesticide was 1% in dipping solution. Similarly, malathion exposed poultry meat failed in altering any significant change in the pancreatic amylase and lipase activities of rats. This study concludes the virtual absence of toxic accumulation of pesticide in the meat of birds after 168 hrs of exposure in usual concentration range upto 1.5%.

• 말소리와 음성과학
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• 제2권2호
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• pp.117-121
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• 2010

The This study aimed to evaluate the effects of the voice therapy we operated to the patients with age-related dysphonia. Thirty four participants who were diagnosed as age-related dysphonia in laryngoscopic finding from January, 2009 to December, 2009 completed the study. The participants were aged from 60 to 82 years old with a mean age of 70.6. All participants had received the abdominal breath technique, SKHPIP with laughter, and basic vocal training with description of their problem, the length of which ranged from four sessions to twelve sessions. We executed the videostroboscopy to compare the aspect of voicing change and the perceptual assessment, voice range profile, acoustic and aerodynamic measures to identify change of voice. Participants had glottal gap due to incomplete glottic closure during voicing on the pretest. After they took the voice therapy, the glottic gap became narrow and rough and breathy voice was reduced. There were significant difference in acoustic and aerodynamic measures. Jitter, Shimmer, MFR were reduced and MPT, Psub were increased(p<.05). Participants' pitch range and intensity range were increased on the posttest performance after taking voice therapy. Especially, most of them were showed that pitch range was increased significantly in high frequency area. The results of this investigation indicate that the voice therapy using abdominal breath, SKHPIP, and exercise together is effective for the patients who have age-related dysphonia to improve their voice quality. We recommend to apply this technique to functional voice disorders who are showed glottal gap.

• 물과 미래
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• 제19권4호
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• pp.355-364
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• 1986

본 연구는 해빈변형과정에 침식과 퇴적사이의 상사성을 현지 및 실험실에서 결정하려고 수행되었다. 얻어진 결과는 다음과 같았다. (1) Horikawa 식의 이론을 적용하여 연구한바 침식과 퇴적사이의 상사성을 C값만으로 결정하기는 곤란함을 알았다. (2) $H_//L_0$식만의 값으로 상사성을 결정하기는 곤란하였다. (3) $H_//L_0$와 C, $H_//L_0$와 $N_{sr}$의 무차원값을 현지 및 실험실에서 관찰한바에 의하면 $H_//L_0$가 0.024에서 침식, 퇴적이 구분되어 상사가 이루어졌다. (4) 파형경사를 알면 침식, 퇴적을 구분하는데 크게 도움이 될 것이다.