• Natural Product Sciences
• /
• v.25 no.2
• /
• pp.103-110
• /
• 2019

We investigated the anti-inflammatory effect of Pyunkang-tang extract (PGT), a complex herbal extract based on traditional Chinese medicine that is used in Korea for controlling diverse pulmonary diseases, on cigarette smoke-induced pulmonary pathology in a rat model of chronic obstructive pulmonary disease (COPD). The constituents of PGT were Lonicerae japonica, Liriope platyphylla, Adenophora triphilla, Xantium strumarinum, Selaginella tamariscina and Rehmannia glutinosa. Rats were exposed by inhalation to a mixture of cigarette smoke extract (CSE) and sulfur dioxide for three weeks to induce COPD-like pulmonary inflammation. PGT was administered orally to rats and pathological changes to the pulmonary system were examined in each group of animals through measurement of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interleukin-6 (IL-6) levels in bronchoalveolar lavage fluid (BALF) at 21 days post-CSE treatment. The effect of PGT on the hypersecretion of pulmonary mucin in rats was assessed by quantification of the amount of mucus secreted and by examining histopathologic changes in tracheal epithelium. Confluent NCI-H292 cells were pretreated with PGT for 30 min and then stimulated with CSE plus PMA (phorbol 12-myristate 13-acetate), for 24 h. The MUC5AC mucin gene expression was measured by RT-PCR. Production of MUC5AC mucin protein was measured by ELISA. The results were as follows: (1) PGT inhibited CSE-induced pulmonary inflammation as shown by decreased TNF-${\alpha}$ and IL-6 levels in BALF; (2) PGT inhibited the hypersecretion of pulmonary mucin and normalized the increased amount of mucosubstances in goblet cells of the CSE-induced COPD rat model; (3) PGT inhibited CSE-induced MUC5AC mucin production and gene expression in vitro in NCI-H292 cells, a human airway epithelial cell line. These results suggest that PGT might regulate the inflammatory aspects of COPD in a rat model.

• The Journal of the Korea Contents Association
• /
• v.22 no.10
• /
• pp.213-224
• /
• 2022

This study aims to propose the directions of design strategies and product development by analyzing the style types and design features of sneakers using the knitted upper which has been rapidly increasing due to merits in a variety of aspects including goods, production and marketing aspects. To this end, this study analyzed total 924 style types which had been gaining popularity in online markets and brand products drawing attention in the sneaker market with the knitted upper and their design features. In accordance with the analysis results, uniqueness was identified as the first merit. The unique hybrid style and design of sneakers with the knitted upper have been established without complying with the conventional materials and production techniques. The next merit was multimodality. The sneakers with the knitted upper create multiple images highlighting each feature of colors and materials by mixing those elements in various ways. The third merit was experimentality. The sneakers with the knitted upper have been attempted decisive change of designs by combining more engineering approach and new materials and techniques than existing sneakers. In these days when the sneaker market has been gradually expanded, the analysis results of this study reflecting the industrial trends will provide the fundamental data for a variety of research activities related to shoes and for the direction of brand planning in the relevant industries.

• Journal of The Korean Association For Science Education
• /
• v.15 no.2
• /
• pp.173-184
• /
• 1995

The purpose of this study was to analyse the problems of 'Science Inquiry Experiment Contest(SIEC)' which was one of 8 programs of 'The 2nd Student Science Inquiry Olympic Meet(SSIOM)'. The results and conclusions of this study were as follows: 1. It needs to reconsider the role of practical work within science experiment because practical work skills form one of the mainstays in current science. But the assessment of students' laboratory skills in the contest was made little account of. It is necessary to remind of what it means to be 'good at science'. There are two aspects: knowing and doing. Both are important and, in certain respects, quite distinct. Doing science is more of a craft activity, relying more on craft skill and tacit knowledge than on the conscious application of explicit knowledge. Doing science is also divided into two aspects, 'process' and 'skill' by many science educators. 2. The report's and checklist's assessment items were overlapped. Therefore it was suggested that the checklist assessment items were set limit to the students' acts which can't be found in reports. It is important to identify those activities which produce a permanent assessable product, and those which do not. Skills connected with recording and reporting are likely to produce permanent evidence which can be evaluated after the experiment. Those connected with manipulative skills involving processes are more ephemeral and need to be assessed as they occur. The division of student's experimental skills will contribute to the accurate assess of student's scientific inquiry experimental ability. 3. There was a wide difference among the scores of one participant recorded by three evaluators. This means that there was no concrete discussion among the evaluators before the contest. Despite the items of the checklists were set by preparers of the contest experiments, the concrete discussions before the contest were necessary because students' experimental acts were very diverse. There is a variety of scientific skills. So it is necessary to assess the performance of individual students in a range of skills. But the most of the difficulties in the assessment of skills arise from the interaction between measurement and the use. To overcome the difficulties, not only must the mark needed for each skill be recorded, something which all examination groups obviously need, but also a description of the work that the student did when the skill was assessed must also be given, and not all groups need this. Fuller details must also be available for the purposes of moderation. This is a requirement for all students that there must be provision for samples of any end-product or other tangible form of evidence of candidates' work to be submitted for inspection. This is rather important if one is to be as fair as possible to students because, not only can this work be made available to moderators if necessary, but also it can be used to help in arriving at common standards among several evaluators, and in ensuring consistent standards from one evaluator over the assessment period. This need arises because there are problems associated with assessing different students on the same skill in different activities. 4. Most of the students' reports were assessed intuitively by the evaluators despite the assessment items were established concretely by preparers of the experiment. This result means that the evaluators were new to grasp the essence of the established assessment items of the experiment report and that the students' assessment scores were short of objectivity. Lastly, there are suggestions from the results and the conclusions. The students' experimental acts which were difficult to observe because they occur in a flash and which can be easily imitated should be excluded from the assessment items. Evaluators are likely to miss the time to observe the acts, and the students who are assessed later have more opportunity to practise the skill which is being assessed. It is necessary to be aware of these problems and try to reduce their influence or remove them. The skills and processes analysis has made a very useful checklist for scientific inquiry experiment assessment. But in itself it is of little value. It must be seen alongside the other vital attributes needed in the making of a good scientist, the affective aspects of commitment and confidence, the personal insights which come both through formal and informal learning, and the tacit knowledge that comes through experience, both structured and acquired in play. These four aspects must be continually interacting, in a flexible and individualistic way, throughout the scientific education of students. An increasing ability to be good at science, to be good at doing investigational practical work, will be gained through continually, successively, but often unpredictably, developing more experience, developing more insights, developing more skills, and producing more confidence and commitment.

• Science of Emotion and Sensibility
• /
• v.14 no.1
• /
• pp.17-26
• /
• 2011

Health care service's added value and sustainability has been formed, through the product developing about sports equipment and special equipment for disabled in order to improve the life quality, with the increasing population of elderly and the attention about health care. This research's design and 3 testing sections has been done according to design process for design development of functional bike. 1st test is done through researching from 4 aspects: structure, aesthetic, function and using. In the 2nd testing, 10 universal design items were used to evaluate 10 modeling samples, and sample F which has high evaluation overall was chosen. In 3rd test, evaluation was done from the user service scene about the mock-up with 1/4 scale size. PPP (product performance program) which is constructed with 60 evaluation items about functional bike's service was tested, and these items were fixed through discussing with experts. Through the result we knew the aesthetic elements had relationship with proportion, unity and typicality. In 10 items (55 survey items), the scores of items with physical exposure's minimization, simple and intuitively usage showed high, on the contrary, the other items' scores was very low, such as information delivery's consideration and thought, failure preventing. The evaluation will be done once more by health care experts, designers and elderly together if the physical model could be made for getting accurate measurement about above test result in the future.

• Science of Emotion and Sensibility
• /
• v.8 no.1
• /
• pp.17-28
• /
• 2005

With the advent of computer technology, the fundamental nature of products has shaped from physical forms towards product interactivity, The focus is now on usability of the product with ease and efficiency rather than conversing with just the looks of the product. However, most definitions of usability and contemporary usability-related researches, have focused on the performance-oriented functional aspects of usability (i.e., how well users perform tasks using a product). Today, user expectations are higher; products that bring not only functional benefits but also emotional satisfaction. So far, there have been many studies on human emotions and the emotional side of products in the field of emotional engineering. Contemporary emotion-related researches have focused mainly on the relationship between product aesthetics and the emotional responses elicited by the products, but little is known about emotions elicited from using the products. The main objective of our research is analyzing user's emotional changes while using a product, to reveal the influence of usability on human emotions. In this research, we suggested conceptual framework for the study on the relationship between usability of products, and human emotions with emphasis on mobile phones. We also extracted emotional words for measuring user's emotions expressed not from looking at the product's appearance, but from using the product. First, we assembled a set of emotions that is sufficiently extensive to represent a general overview of the full repertoire of Korean emotions from the literature study. Secondly, we found emotional words in the after note by the users on the websites. Finally, verbal protocols in which the user says out loud what he/she ks feeling while he/she ks carrying out a task were collected. And then, the appropriateness of extracted emotional words was verified by the members of the consumer panel of a company through web survey. It is expected that emotional words extracted in this research will be used to measure user's emotional changes while using a product. Based on the conceptual framework suggested in this research, basic guidelines on interface design methods that reflect user's emotions will be illustrated.

• Applied Chemistry for Engineering
• /
• v.17 no.2
• /
• pp.163-169
• /
• 2006

A Life Cycle Assessment (LCA) study was carried out to identify and improve the environmental aspects associated with the present incineration system of spent Li-ion batteries (LIBs) in Korea. The environmental impact associated with the landfill of the incineration ash was also assessed in this study, while so far it was excluded in most studies. It was found out that the $CO_{2}$ emission from the electricity generation as well as the incineration process and heavy metals emissions to air and water accounted for about 90% of total environmental impacts. In particular, the effect of the emission of heavy metals were dominant. In oder to improve the current incineration system environmentally, it is needed to incinerate the wastes like spent LIBs which contained relatively high portion of heavy metals separately from other combustible wastes. On the other hand, the effect of the landfill of ash after incineration was insignificant since the ash from the incineration process was chemically stable.

• Industrial Engineering and Management Systems
• /
• v.11 no.2
• /
• pp.155-164
• /
• 2012

As the global market becomes more competitive, manufacturing industries face relentless pressure caused by a growing tendency of greater varieties of products, shorter manufacturing cycles and more sophisticated customer requirements. Efficient and effective supplier selection and order allocation decisions are, therefore, important decisions for a manufacturer to ensure stable material flows in a highly competitive supply chain, in particular, when customers are willing to accept products with less desirable product attributes (e.g., color, delivery date) for economic reasons. This paper attempts to solve optimally the challenging problem of supplier selection and order allocation, taking into consideration the customer flexibility for a manufacturer producing multi-products to satisfy the customers' demands in a multi period planning horizon. A new mixed integer programming model is developed to describe the behavior of the supply chain. The objective is to maximize the manufacturer's total profit subject to various operating constraints of the supply chain. Due to the complexity and non-deterministic polynomial-time (NP)-hard nature of the problem, an improved genetic approach is proposed to solve the problem optimally. This approach differs from a canonical genetic algorithm in three aspects: a new selection method to reduce the chance of premature convergence and two problem-specific repair heuristics to guarantee feasibility of the solutions. The results of applying the proposed approach to solve a set of randomly generated test problems clearly demonstrate its excellent performance. When compared with applying the canonical genetic algorithm to locate optimal solutions, the average improvement in the solution quality amounts to as high as ten percent.

• The Journal of the Korea Contents Association
• /
• v.15 no.7
• /
• pp.664-673
• /
• 2015

The assistive devices for disabled people are being highlighted even in industrial aspects through the policy and support for disabled people, enactment of regulation for the improvement of accessibility of disabled, technological innovation and product development. Recently, internet access with the sense of touch and hearing and utilizing electronic publishing contents and e-mailing are being convenient through the product of ICT development such as screen reader for visually impaired people, braille display, screen enlarger, text converter and others. Even so, in rapidly changing digital media smart era, the accessibility of visually impaired people is still poor and assistive devices and alternative formats are in need of improvement. Therefore, in aspect of the research and development innovation, this study proposes the implementation directions for improvement of accessibility by analyzing the current situation and structure of alternative formats and assistive devices for visually impaired people. As a result, in the future, various types of digital information are expected to be converted into a customized and realistic forms and distributed through a dedicated disability products or smart devices.

• Journal of Korea Society of Digital Industry and Information Management
• /
• v.10 no.2
• /
• pp.173-186
• /
• 2014

There are a variety of alternative products in the computer markets. A tablet PC, which is a small type of computer, is expanding its market share as an independent type of computer products. The purpose of this study is to find out what the factors are that led to the success of the tablet PC. A research study was carried out on the intention to use of tablet PCs by consumers. The factors that affect the intention to use of tablet PCs users were structured on the basis of attitude theory. According to the one-dimensional theory of attitude, cognitive factors affect the affective factors, which in turn affect conative factors. In the study, the relations between each dimension were set up. The hypothesis was tested by structural equation modeling. The test results are as follows. First, the values and satisfaction that the owners of tablet PCs feel from the products and the positive comments on the products from their nearby acquaintances affect in a positive way how much they like their products. Second, the products surrounding the tablet PCs did not affect the intention to use of the products. Third, the product favorability that the owners of tablet PCs feel affects the intention to use in a meaningful way. The results of the research also show that hi-tech products such as tablet PCs affect their attitude after they buy and use the products. This attitude affects intention to use of the products. The managers of companies that produce hi-tech products should consider the cognitive and affective aspects of the product owners when manufacturing and marketing products.

• Journal of Distribution Science
• /
• v.17 no.6
• /
• pp.85-90
• /
• 2019

Purpose - In China, electric vehicle industry has been increased attention as a environmental friendly transportation to solve pollution problems, and still growing to solve a technological gap issues in automobile industry. Although the interest of electric vehicle is getting bigger, there are not many studies that showing consumers' intention to purchase an electric vehicle. Because of this phenomenon, this study tried to find the factors which can affect the purchase intention of electric vehicle. Research design, data, and methodology - Drawing on the Planned Behavior Theory(TPB), this study examined attitude toward the behavior, subjective norm of environmental protection, and the influence of economic benefits on purchase intention through survey. we measure 233 Chinese samples. Results - The results showed that attitude toward electric vehicles, subjective norms of environmental protection, and economic benefits had a significant effect on purchase intention. To be specific, the consciousness of environmental protection, economic considerations, product image and its characteristic are all considerable aspects from the standpoint of Chinese consumers. In addition, we found that the higher the age group, the weaker relationship between attitude toward electric vehicle and purchase intention. Conclusion - This study suggests that diverse factors related to the purchase intention of electric car in China market and Chinese consumers. Especially, economic benefit factors, which have a statistically significant and significant influence on the purchase intention of electric vehicles, are not significant variables in the existing electric vehicle research. This result is considered to be the result of the fact that the electric vehicle is not only an automobile having an environmentally friendly factor but also a product which makes it consider the economic situation. Put together, the results of this paper give us the theoretical basis for establishing an electric vehicle marketing strategy in the rapidly changing Chinese market. Also, this paper will provide new ventures for marketing and distribution strategies for Korean companies that are looking to expand into China.