• Parasites, Hosts and Diseases
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• v.27 no.1
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• pp.1-8
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• 1989

Serodiagnosis of parasitic infections is widely used, since parasites or their eggs are not always detected by ordinary methods. The sensitive tests such as ELISA are highly dependent on the purity of antigens used. To solve this problem. many workers have tried to find species-specific components of antigens, The present study was performed to determine the antigenic profile of crude saline extracts of 3, 5, 8 and 12-week old p. westermani worms, which were collected from experimentally infected cats, based on SDS-PAGE and immunoblot technique. The results were as follows: 1. The SDS-PAGE showed at least 30 Protein bands ranging from 229 kDa to 10 kDa molecular weight. The protein components of p. wsstermani changed chronologically during its developmental period. The 229 kDa band was recognized only in 12-week old worms ($$SEP_{l2}$). 2. Analysis by ELISA showed a significant increase in antibody levels at 3 weeks in infected cats using crude saline extract antigens ($SEP_3,{\;}SEP_5,{\;}SEP_8,{\;}SEP_{l2}$). 3. By EITB using $SEP_3$ and $SEP_5$ infected cats recognisea major protein bands with molecular weight of 60, 35, 28, 25 or 21 kDa at 3~12 weeks of infection, and 3 additional antigens, 19, 13 and 10 kDa, were detected at 8~12 weeks of infections. 4. Using $SEP_8$ 5 antigens, 91, 85, 31, 25 and 21 kDa, were consistently detected by all infected sera tested. In addition, 3 antigens of lg. 13 and 10 kDa were detected at 8~12 weeks of infection. Using $SEP_12$, similar results were obtained with that by using $SEP_8$ and 1 additional antigen of 229 kDa, specifically reacting with the sera from 12 weeks of in(traction, was recognized.

• Land and Housing Review
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• v.3 no.4
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• pp.343-355
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• 2012

The purpose of this paper is to propose reasonable improvements of demand estimation methods of commercial site through the case study. Thus, we investigated the problems and limitation of demand estimation methods and process applied to primary and secondary new towns in Korea. And we suggested the way to reduce error of demand estimation and to raise its objectivity. The result of case analysis is as follows; firstly, it was insufficient to consider location, hierarchy and change of land use like mixed-use development in commercial site. Secondly, improper comparable group or operated relevant index data in the same light were selected the aggregated unit requirement method such as comparative analogy method and planning guidelines. Thirdly, there were many cases that demand estimation value was amended arbitrarily, and it tends to occur a serious reliability problem. Therefore, to improve these problems and to make better use of demand estimation hereafter are required the sublation of arbitrary commercial sphere's settings, the making of comparative group considered development conditions, and putting forward objective revision basis.

• Journal of Educational Research in Mathematics
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• v.24 no.2
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• pp.181-204
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• 2014

This research aims to have some implications for revision of curriculum and textbooks by analysing connections between the 2009 revised national curriculum and its textbooks in elementary school mathematics. The results of analyses for 3~4 grades can be summarized in four aspects: Firstly, we noticed that the reconstructed achievement criteria were reflected properly in the textbooks except for use of calculators in 'Numbers and Operations'. Secondly, the analysis of connections between unit objectives of textbooks and the reconstructed achievement criteria suggests that 10 units must receive attention. Especially, the range of decimal numbers for adding and subtracting needs to be corrected. Thirdly, mathematical terms and symbols excluding 'unit fraction' were found in the textbooks. Finally, mathematical processes were also fully reflected in the textbooks. However 'simplifying' as a strategy for problem solving was only missing. This result shows good or poor connections between the curriculum and its textbooks, therefore it is expected to be used effectively to revise the national curriculum for mathematics and its textbooks.

• Journal of Internet Computing and Services
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• v.19 no.1
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• pp.87-95
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• 2018

Due to global warming and increased energy costs around the world, interests of energy saving and efficiency have been increased. In particular, forging factories need methods to save energy and increase productivity because of needing amounts of energy uses. To solve the problem, we propose a system, which includes collection, monitoring, and analysis process, to monitor energy uses each facility in realtime based on the IoT devices. This system insists of worksheets management, facility/energy management, realtime monitoring, history search, data analysis through connecting with existed ERP/MES Systems in manufacturing factories. The energy monitoring process is to present used energy collected from IoT devices connected with installed gasmeter and wattmeter each facility. This system provide the change of energy uses, usage fee, energy conversion, and green gas information in realtime on Web and mobile devices. This system will be enhanced with energy saving technology by analyzing constructed big data of energy uses. We can also propose a method to increase productivity by integrating this system with functions of digitalized worksheets and optimized models for production process.

• Applied Chemistry for Engineering
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• v.23 no.1
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• pp.18-22
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• 2012

Photocurable binder for a transparent glass fiber composite was prepared with alicyclic methacrylate and fluorene-based diacrylate. ANOVA (analysis of variance) analysis was used to know main factors affecting the conversion of photocurable binder. It showed radiation intensity and photoinitiator (PI) concentration were main factors. The conversion of photocurable binder was simply increased with radiation intensity. Its increment however was abated with increasing PI concentration. We found that average conversion of the binder measured by FTIR-ATR was 87% when it was exposed to $5J/cm^2$ of UV dose with 5 wt% of PI. Oxime ester type PI was very effective to get a high degree of conversion, but it caused a yellowing problem. Owing to post-baking process, UV cured film showed an improved thermal stability by increase of conversion and removal of volatile organic compounds. TG% at $260^{\circ}C$ of film cured with 5 wt% of PI (TPO+MBF) and $5J/cm^2$ of UV radiation increased from 95.4 to 99.0% by post-baking at $230^{\circ}C$ for 5 min.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.26 no.1
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• pp.25-33
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• 2015

Background and Objectives:The objective of this study was to investigate the features of post-thyroidectomy subjective voice disorder by Voice Handicap Index (VHI) and Voice Symptom Scale (VOISS) through aerodynamic analysis and to investigate the appropriate voice therapy intervention. Materials and Methods:Twenty post-thyroidectomy patients who had no recurrent laryngeal nerve paralysis through laryngeal stroboscopy were enrolled for this study. Acoustic and aerodynamic evaluations were performed before operation, 2 weeks and 3 months after operation. Subjective voice evaluation was performed by VHI and VOISS. Aerodynamic evaluation was compared and analysed by maximum phonation time(MPT), phonation threshold pressure(PTP), mean air flow rate(MFR), etc. Subjective voice evaluation was surveyed through VHI and VOISS. To evaluate patients' symptoms related to functional voice disorder, scores on physical domain in VHI and VOISS were selected to be compared for each session. Results: The 10 out of 20 participants who complained of voice symptoms had no significant difference with pre-operation in acoustic evaluation, but all showed higher scores on 2 weeks and 3 months after operation compared to pre-operation, in VHI-physical domain and selected questionnaires in VOISS. They reduced MPT and increased PTP value simultaneously. Laryngeal massage and breathing training were simultaneously treated to them, 5 participants resulting in improvement in MPT and PTP compared to pre-treatment. Conclusion:Patients who complained voice change with no organic damage after thyroidectomy were all shown to have reduced MPT and increased PTP in some by aerodynamic evaluations. Reduced MPT may imply some problem in air flow beneath glottis. Increased PTP suggests much more effort in vocalization mechanism than pre-operation. Comparing aerodynamic evaluations in post-thyroidectomy may provide information on behavioral interventions. Additionally, study on laryngeal massage and breathing training simultaneously treated to patients with such voice disorder is needed to be conducted with larger number of participants.

• Korean Journal of Head & Neck Oncology
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• v.13 no.2
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• pp.213-220
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• 1997

Background: Thyroid cancer is a relatively rare neoplasm and its incidence varies geographically and ethnically around the world. Thyroid cancer is the most common endocrine malignancy, but it has a wide spectrum of biologic behavior, histologic appearance, and management. Purpose: The purpose of the study was to analyse and evaluate all aspects of the clinical consideration in thyroid cancer. Method: Between 1986 and 1995, a retrospective analysis of 77 thyrod cancer patients admitted at the Department of Surgery, Hangang Sacred Heart Hospital, Hallym University was made to assess clinical entities. Result: By the pathological classification, the papillary carcinoma was the most common type(83.1%). Male to female ratio was 1 : 5.4 and most prevalent age group was noted from fourth decade to fifth decade(46.8%). The most common duration of illness between the appearance of the symptoms and the treatment was below 6 months(44.2%), and the most common symptom was the palpable mass at the anterior portion of the neck(96.1%). Most cases of the thyroid cancer were appeared as cold nodule in the $^{99m}$Tc-thyroid scan(95.7%). In the site of tumor location, the right and left lobe was distributed similarly. In the extent of tumor, incidence of intrathyroidal location was 41.6%, and that of the metastasis to the cervical lymph nodes was 44.2% and that of the direct capsular invasion was 27.3%, and incidence of both involved case was 13%. Surgical procedures were total thyroidectomy alone in 27 cases(35.1%) or with modified neck dissection in 6 cases(7.8%), or with radical neck dissection in 2 cases (2.6%), near total thyroidectomy alone in 22 cases(28.6%), ipsilateral lobectomy with isthmectomy alone in 12 cases(15.6%) or with modified neck dissection in 1 case(1.3%), and biopsy only in 7 cases(9.1%). The most common postoperative complications were transient hypoparathyroidism(5.2%) and transient unilateral recurrent laryngeal nerve paralysis(5.2%). Conclusion: The major problem of management of thyroid cancer include a wide spectrum of clinical behaviour of this tumor entity, the lack of reliable prognostic factors and lack of an objective assessment of the various treatment modalities. But because of showing the favorable prognosis for most thyroid cancer, appropriate and aggressive management should be recommended.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.615-621
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• 2016

This study examines whether there is agency cost in a public R&D subsidy program by applying agency theory. If there is agency cost, the composition ratio of the government subsidy and the firm's own R&D fund would have a significant (-) effect on technological performance. Companies that received a public R&D subsidy in Korea from 2000 to 2009 were selected as a sample. Frequency analysis and multiple regression analysis were used. The independent variables was the ratio of public R&D subsidy cost to the Firm's own R&D cost, and the dependent variables were the number of patent applications and the number of patents registered. The control variables were firm size and R&D cost. The results show that there are agency problems in the government-sponsored R&D system. A future study is needed to examine how much agency problems deteriorate the efficiency of the system.

• Journal of KIISE:Software and Applications
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• v.35 no.2
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• pp.118-127
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• 2008

In this paper, we propose a method for construction of robust 3D statistical shape model in the mandible CT datasets. Our method consists of following four steps. First, we decompose a 3D input shape Into patches. Second, to generate a corresponding shape of a floating shape, all shapes in the training set are parameterized onto a disk similar to the patch topology. Third, we generate the corresponding shape by one-to-one mapping between the reference and the floating shapes. We solve the problem failed to generate the corresponding points near the patch boundary Finally, the corresponding shapes are aligned with the reference shape. Then statistical shape model is generated by principle component analysis. To evaluate the accuracy of our 3D statistical shape model of the mandible, we perform visual inspection and similarity measure using average distance difference between the floating and the corresponding shapes. In addition, we measure the compactness of statistical shape model using the modes of variation. Experimental results show that our 3D statistical shape model generated by the mandible CT datasets with various characteristics has a high similarity between the floating and corresponding shapes and is represented by the small number of modes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.5
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• pp.1791-1798
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• 2010

This research predicted the change and characteristics of space structure by new residential area development through objective and quantitative analysis of urban spatial configuration using space syntax and associated the prediction with the city status statistics data and quantitative analysis, and the results are summarized as follows: (1) If large scale new residential area of Dongnae township proceeds to be developed according to present plan, accessibility to the new residential area will drop, and also as the outside space ripple effects by new residential area development also are anticipated small, the new residential area apprehensibly will not succeed to play the role of integrating the entire city structurally, but will cause structural problem, severing the city structure. (2) If the city planned road between existing urban center planned based on 2004 Chuncheon city plan overall drawing and main road which is the entrance road of the planned new residential area is developed together, the accessibility to the entire space of Chuncheon city and the new residential area will be easy, allowing the new residential area properly integrated into the entire space of Chuncheon city, consequently giving a prediction that classification of land use between the central part of Chuncheon city and surrounding residential area would become conspicuous.