• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8993-9004
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• 2014

Background: The incidence rate and the treatment costs of hepatocellular carcinoma (HCC) are high, especially in Thailand. Previous studies indicated that early detection by a surveillance program could help by down-staging. This study aimed to compare the costs and health outcomes associated with the introduction of a HCC surveillance program with no program and to estimate the budget impact if the HCC surveillance program were implemented. Materials and Methods: A cost utility analysis using a decision tree and Markov models was used to compare costs and outcomes during the lifetime period based on a societal perspective between alternative HCC surveillance strategies with no program. Costs included direct medical, direct non-medical, and indirect costs. Health outcomes were measured as life years (LYs), and quality adjusted life years (QALYs). The results were presented in terms of the incremental cost-effectiveness ratio (ICER) in Thai THB per QALY gained. One-way and probabilistic sensitivity analyses were applied to investigate parameter uncertainties. Budget impact analysis (BIA) was performed based on the governmental perspective. Results: Semi-annual ultrasonography (US) and semi-annual ultrasonography plus alpha-fetoprotein (US plus AFP) as the first screening for HCC surveillance would be cost-effective options at the willingness to pay (WTP) threshold of 160,000 THB per QALY gained compared with no surveillance program (ICER=118,796 and ICER=123,451 THB/QALY), respectively. The semi-annual US plus AFP yielded more net monetary benefit, but caused a substantially higher budget (237 to 502 million THB) than semi-annual US (81 to 201 million THB) during the next ten fiscal years. Conclusions: Our results suggested that a semi-annual US program should be used as the first screening for HCC surveillance and included in the benefit package of Thai health insurance schemes for both chronic hepatitis B males and females aged between 40-50 years. In addition, policy makers considered the program could be feasible, but additional evidence is needed to support the whole prevention system before the implementation of a strategic plan.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.4 no.3
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• pp.75-83
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• 1984

The probability of failure is used to analyze the reliability of three dimensional slope failure, instead of conventional factor of safety. The strength parameters are assumed to be normal variated and beta variated. These are interval estimated under the specified confidence level and maximum likelihood estimation. The pseudonormal and beta random variables are generated using the uniform probability transformation method according to central limit theorem and rejection method. By means of a Monte-Carlo Simulation, the probability of failure is defined as; $P_f=M/N$ N: Total number of trials M: Total number of failures Some of the conclusions derived. from the case study include; 1. Three dimensional factors of safety are generally much higher than 2-D factors of safety. However situations appear to exist where the 3-D factor of safety can be lower than the 2-D factor of safety. 2. The $F_3/F_2$ ratio appears to be quite sensitive to c and ${\phi}$ and to the shape of the 3-D shear surface and the slope but not to be to the unit weight of soil. 3. From the two models (normal, beta) considered for the distribution of the factor of safety, the beta distribution generally provides lager than normal distribution. 4. Results obtained using the beta and normal models are presented in a nomgraph relating slope height and slop angle to probability of failure.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.382-395
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• 2013

The providers of meteorological information want to know the level of satisfaction of forecast users with their services. To provide better service, meteorological communities of each nation are administering a survey on satisfaction of forecast users. However, most researchers provided these users with simple questionnaires and the respondents had to choose one answer among different satisfaction levels. So, the results of this kind of survey have low explanation power and are difficult to use in developing strategy of forecast service. In this study, instead of cost-loss concept, we applied satisfaction-dissatisfaction concept to the $2{\times}2$ contingency table, which is a useful tool to evaluate value of forecast, and estimated satisfaction value of 24h precipitation forecasts in Shanghai, China and Seoul, Korea. Moreover, not only the individual satisfaction value of forecast but the user group's satisfaction value was evaluated. As for the result, it is effective to enhance forecast accuracy to improve the satisfaction value of deterministic forecast user group, but in the case of probabilistic forecast, it is important to know the level of dissatisfaction of user group and distribution of probability threshold of forecast users. These results can help meteorological communities to search for a solution which can provide better satisfaction value to forecast users.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.46 no.3
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• pp.219-229
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• 2018

This paper proposes Kalman Filter-based relative navigation algorithms for proximity tasks such as rendezvous/docking/cluster-operation of spacecraft using PSD Sensors and Infrared Beacon Modules. Numerical simulations are performed for comparative analysis of the performance of each relative-navigation technique. Based on the operation principle and optical modeling of the PSD Sensor and the Infrared Beacon Module used in the relative navigation algorithm, a measurement model for the Kalman filter is constructed. The Extended Kalman Filter(EKF) and the Unscented Kalman Filter(UKF) are used as probabilistic relative navigation based on measurement fusion to utilize kinematics and dynamics information on translational and rotation motions of satellites. Relative position and relative attitude estimation performance of two filters is compared. Especially, through the simulation of various scenarios, performance changes are also investigated depending on the number of PSD Sensors and IR Beacons in target and chaser satellites.

• Journal of Korean Society of Steel Construction
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• v.20 no.6
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• pp.723-730
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• 2008

Due to the higher ratio of live load to total loads of railway bridges, the accumulated damage by cyclic fatigue is significant. Moreover, it is highly possible that the initiated crack grows faster than that of highway bridges. Therefore, it is strongly needed to assess the safety for the accumulated damage analytically. The initiation and growth of fatigue-crack are related with the stress range, number of cycles, and the stiffness of the structural system. The stiffness of the structural system includes uncertainties of the planning, design, construction and maintenance, which varies as time goes. In this study, the authors developed the design and risk assessment techniques based on the reliability theories considering the uncertainties in load and resistance. For the probabilistic risk assessment of crack growth and the remaining life of the structures by the cyclic load of railway and subway bridges, response surface method (RSM) combined with first order second moment method were used. For composing limit state function, the stress range, stress intensity factor and the remaining life were selected as input important random variables to the RSM program. The probabilities of failure and the reliability indices of fatigue life for the considered specimen under cyclic loads were evaluated and discussed.

• School Mathematics
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• v.15 no.3
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• pp.603-617
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• 2013

The major purpose of this article is to examine what kind of gap exists between mathematically gifted students' probability knowledge and the reality actually applying that knowledge and then analyze the cause of the gap. To attain the goal, 23 elementary mathematically gifted students at the highest level from G region were provided with problem situations internalizing a probability and expectation, and the problems are in series in which conditions change one by one. The study task is in a gaming situation where there can be the most reasonable answer mathematically, but the choice may differ by how much they consider a certain condition. To collect data, the students' individual worksheets are collected, and all the class procedures are recorded with a camcorder, and the researcher writes a class observation report. The biggest reason why the students do not make a decision solely based on their own mathematical knowledge is because of 'impracticality', one of the properties of probability, that in reality, all things are not realized according to the mathematical calculation and are impossible to be anticipated and also their own psychological disposition to 'avoid loss' about their entry fee paid. In order to provide desirable probability education, we should not be limited to having learners master probability knowledge included in the textbook by solving the problems based on algorithmic knowledge but provide them with plenty of experience to apply probabilistic inference with which they should make their own choice in diverse situations having context.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.30 no.5
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• pp.371-380
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• 2017

The risk-targeted seismic design concept was first included in ASCE/SEI 7-10 to address problems related to the uniform-hazard based seismic concept that has been constructed without explicitly considering probabilistic uncertainties in the collapse capacities of structures. However, this concept is not yet reflected to the current Korean building code(KBC) because of insufficient strong earthquake data occurred at the Korean peninsula and little information on the collapse capacities of structures. This study evaluates the risk-targeted seismic performance of steel ordinary concentrically braced frames(OCBFs). To do this, the collapse capacities of prototype steel OCBFs are assessed with various analysis parameters including building locations, building heights and soil conditions. The seismic hazard curves are developed using an empirical spectral shape prediction model that is capable of reflecting the characteristics of earthquake records. The collapse probabilities of the prototype steel OCBFs located at the Korean major cities are then evaluated using the risk integral concept. As a result, analysis parameters considerably influence the collapse probabilities of steel OCBFs. The collapse probabilities of taller steel OCBFs exceed the target seismic risk of 1 percent in 50 years, which the introduction of the height limitation of steel OCBFs into the future KBC should be considered.

• International Journal of Contents
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• v.11 no.2
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• pp.37-49
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• 2015

Sensors, equipment, ICT facilities and their corresponding software have a relatively short lifetime relative to that of constructional structure, so these devices have to be continuously fixed or exchanged during maintenance and management. Furthermore, software or analysis tools should be periodically upgraded according to advances in ICT and analysis technology. Conventional monitoring systems have serious problems in that it is difficult for site engineers to modify or upgrade hardware and analysis algorithms. Moreover, we depend on the original system developer when we want to modify or upgrade inner program structures. In this paper, we propose a novel design for integrated maintenance and management of a monitoring system by applying the mobile cloud concept. The system is intended for use in disaster prevention of constructional structures, including bridges, tunnels, and in traditional buildings in a local heritage village, we analyze the status of these structures over a long term or a short-term period as well as in disaster situations. Data are collected over a mobile cloud and future expectations are analyzed according to probabilistic and statistical techniques. We implement our integrated monitoring system to solve the existing problems mentioned above. The final goal of this study is to design and implement a monitoring system for more than 10,000 structures spread within Korea. Furthermore, we can specifically apply the monitoring system presented here to a bridge made from timber in Asan Oeam Village and a traditional house in Andong Hahoe Village to monitor for possible disasters. The entire system design and implementation can be developed on the LinkSaaS platform and the monitoring services can also be implemented on the platform. We prove that the proposed system has good performance by performing a TTA authentication test, web accommodation test, and operation test using emulated data.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.5
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• pp.671-683
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• 2018

The flood damage caused by heavy rains in urban watershed is increasing, and, as evidenced by many previous studies, urban flooding usually exceeds the water capacity of drainage networks. The flood on the area which considerably urbanized and densely populated cause serious social and economic damage. To solve this problem, deterministic and probabilistic studies have been conducted for the prediction flooding in urban areas. However, it is insufficient to obtain lead times and to derive the prediction results for the flood volume in a short period of time. In this study, IDNN, TDNN and NARX were compared for real-time flood prediction based on urban runoff analysis to present the optimal real-time urban flood prediction technique. As a result of the flood prediction with rainfall event of 2010 and 2011 in Gangnam area, the Nash efficiency coefficient of the input delay artificial neural network, the time delay neural network and nonlinear autoregressive network with exogenous inputs are 0.86, 0.92, 0.99 and 0.53, 0.41, 0.98 respectively. Comparing with the result of the error analysis on the predicted result, it is revealed that the use of nonlinear autoregressive network with exogenous inputs must be appropriate for the establishment of urban flood response system in the future.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.6
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• pp.651-656
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• 2014

Corrosion has a significant influence upon the reliability assessment and the maintenance planning of gas pipeline. Corrosion defects occurred on the underground pipeline can be obtained by conducting periodic in-line inspection (ILI). However, little study has been done for practical use of ILI data. This paper deals with remaining lifetime prediction of the gas pipeline in the presence of corrosion defects. Because a pipeline parameter includes uncertainty in its operation, a probabilistic approach is adopted in this paper. A pipeline fails when its operating pressure is larger than the pipe failure pressure. In order to estimate the failure probability, this paper uses First Order Reliability Method (FORM) which is popular in the field of structural engineering. A well-known Battelle code is chosen as the computational model for the pipe failure pressure. This paper develops a Matlab GUI for illustrating failure probability predictions Our result indicates that clustering of corrosion defects is helpful for improving a prediction accuracy and preventing an unnecessary maintenance.