• The Journal of the Korean dental association
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• v.49 no.1
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• pp.33-37
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• 2011

The esthetic demands are growing in treatment of primary maxillary incisors as well as permanent ones. There is something dissatisfying about in the keen eyes of the pediatric dentists on their esthetic results of efforts because current tooth color system is created for the purpose of the application to the permanent incisors. In this study using the scientific color measurement device, I would like to introduce a color scheme for the primary maxillary incisors and suggest clinical tips for the better results of resin composite restorations.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3549-3553
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• 2012

Primary small cell carcinoma of urinary bladder is a rare but aggressive disease with poor prognosis and a high mortality rate. It accounts for less than 1 % of all the primary cancers seen in the urinary bladder. Diagnosis and management of this entity poses a challenge to the clinician due to the lack of a standardized protocol for its treatment. Herein we discuss primary small cell carcinoma of the urinary bladder in its entirety.

• Sleep Medicine and Psychophysiology
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• v.12 no.1
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• pp.11-16
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• 2005

Sleep can be easily disrupted by variety of conditions. Most of medical illnesses could be a primary condition causing secondary insomnia. The common underlying mechanism of secondary insomnia is presumed to be stress effects on sleep. The assessment and treatment of secondary insomnia are often complicated. Establishing an causal inference between primary condition and insomnia is the key to assessment. However, it can be difficult even for experienced clinicians due to diagnostic ambiguity of secondary insomnia. Therefore, through medical evaluation and integrative understanding of primary condition is essential to manage secondary insomnia properly. Although treatment have been usually focused on the primary medical illnesses per se, nonpharmacologic interventions, such as sleep hygiene, might be effective in many cases.

• Fashion & Textile Research Journal
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• v.14 no.4
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• pp.648-659
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• 2012

This research categorizes fundamental data needed to develop eco-friendly fabrics treated with bamboo leaf & pine leaf extracts. The effect of mordant on those fabrics was analyzed through the measurement of mechanical properties and the estimation of primary hand values for cotton and silk fabrics dyed with bamboo leaf and pine leaf extracts that were later treated with various mordants. When cotton was dyed with bamboo leaves and pine leaves extracts, EM, WT, 2HB, 2HG, 2HG5, LC, T, and W increased however, RT, SMD, and RC decreased compared to raw cotton fabric. The B, G, and MIU increased after mordant treatment to the dyed cotton and resulted in a stiffer and rougher cotton's hand. EM, WT, RT, MIU, WC, T, and W increased (in terms of silk); however, LT, B, 2HB, G, 2HG, 2HG5, MMD, SMD, and LC decreased compared to raw silk fabric. Similar to the dyed cotton, mordant treatment increased the MIU and LC of dyed silk subsequently, the hand became stiffer and rougher. A greater tannin adsorption results in an increased mechanical property and the primary hand value. For both fabrics, mordant treatment made its smoothness drop. However, the scale of drop for cotton was significant, while the scale of the drop for silk was minor. In terms of type of mordant, femordant and natural-mordant treatment influenced the tensile, shear, surface properties of fabrics, and primary hand values more than Cu-mordant and synthetic-mordant in addition, this increased the stiffness, hardness, and roughness of fabrics.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.4 no.4
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• pp.64-71
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• 2001

Treatment efficiency was examined of a pond-wetland system constructed for water quality conservation of Koheung Estuarine Lake over one year after its establishment in July 2000. The system is composed of primary and secondary ponds in series and six wetland cells in parallel. Cattails (Typha angustiflora) were planted in three wetland cells and common reeds (Phragmites australis) in three other cells. Water pumped from Sinyang Stream flowing into the Lake was funneled into primary pond whose effluent was discharged into secondary pond by gravity flow. Effluent from secondary pond was distributed into each wetland cell. SS, $BOD_5$, T-N, and T-P concentrations in influent to primary pond, and effluent from primary pond, secondary pond, and three wetland cells planted with cattails were analyzed for about one year from August 2000 to August 2001. The removal rates at primary pond for SS, $BOD_5$, T-N and T-P were 29%, 30%, 15%, and 36%, respectively. The abatement rates at secondary pond for SS, $BOD_5$, T-N and T-P were 38%, 40%, 30%, and 47%, respectively. The reduction rates measured at three cattail-planted wetland cells for SS, $BOD_5$, T-N and T-P were 54%, 57%, 60%, and 68%, respectively. Considering early stage of the pond-wetland system and inclusion of winter during the research period, its treatment efficiency was rather good. Cattails had not yet grown to dense stands due to initial establishment period, which resulted in slightly lower treatment efficiencies of wetland cells for these pollutants, compared with those of ponds.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10791-10795
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• 2015

Background: Phyllodes tumors of the breast are rare fibroepithelial lesions, so relatively little is known about this disease entity. The present study was designed to identify differences in clinical features between benign borderline and malignant phyllodes tumors. Materials and Methods: Data from 246 women with phyllodes tumors of the breast treated in Cancer Hospital Chinese Academy of Medical Sciences between 2002 and 2012 were collected and analyzed, including age at presentation, age at treatment, course, size of primary tumor, location, histological type, type of surgery and treatment, local recurrence, distant metastasis, fibroadenoma history, disease-free survival and number of mitosis per 10hpf. There are 125 (55%) benign, 55 (24%) borderline and 47 (21%) malignant tumors. Results: In univariate analysis, average age at presentation, average age at treatment, size of primary tumor, ulceration or not, type of primary surgery, distant metastasis and number of mitosis per 10 hpf turned out to be statistically different among the three PT types (p=0.014, 0.018, <0.000, 0.003, <0.000, 0.001 and <0.000, respectively), while recurrence and disease-free survival (DFS) demonstrated trends for statistical significance (P =0.055 and 0.060, respectively). Multivariate analysis revealed distant metastasis and excision were significantly different in benign, borderline and malignant phyllodes tumors of the breast (p=0.041 and 0.018, OR=0.061 and 0.051). At the same time, size of primary tumor with p=0.052 tended to be different between groups (OR=1.127). However, age at treatment, ulceration and DFS showed no statistically significant variation (p=0.400, 0.286 and 0.413, respectively). Conclusions: Benign borderline and malignant phyllode tumors have different distant metastasis risk, different primary tumor size and different surgical procedures, and malignant PTs are more likely to be bigger and to metastasize.

• The Journal of Korean Obstetrics and Gynecology
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• v.15 no.4
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• pp.228-237
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• 2002

Purpose This study was designed to know how Hyunburikyungtang-gagam effects on dysmenorrhea Method 47 patients visited Oriental Gynecology in Conmaul Oriental Hospital from Jan, 2001 to Jan. 2002 because of their dysmenorrhea were randomly assigned. Hyunbruikyungtang-gagam were prescribed to the patients. Primary and secondary dysmenorrhea change were studied by VASS, MVRS. Written down by the patients before and after the treatment. Results Their ages were $28.62{\pm}4.9$, 18 patients were married and the others were not married. prescription period were $20.59{\pm}0.97$ days, After the treatment, numerical index for the pain was obviously reduced in both primary and secondary dysmenorrhea. Numerical index reduced $5.43{\pm}1.63$(VASS), $3.04{\pm}1.58$(MVRS) in primary dysmenorrhea, and $5.43{\pm}1.63$(VASS), $3.04{\pm}1.58$(MVRS) in secondary dysmenorrhea and there is no difference in effect between primary and secondary dysmenorrhea. But prescribed period was not correration with treatment effects and Pain-reduced period. Conclusion Hyunburikyungtang-gagam has good efficacy on primary and secondary dysmenorrhea, but some more studies are needed on the relationship between treatment effects and Pain-reduced period.

• Genomics & Informatics
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• v.18 no.1
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• pp.6.1-6.9
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• 2020

Acute leukemia represents the most common pediatric malignancy comprising diverse subtypes with varying prognosis and treatment outcomes. New and targeted treatment options are warranted for this disease. Patient-derived xenograft (PDX) models are increasingly being used for preclinical testing of novel treatment modalities. A novel approach involving targeted error-corrected RNA sequencing using ArcherDX HemeV2 kit was employed to compare 25 primary pediatric acute leukemia samples and their corresponding PDX samples. A comparison of the primary samples and PDX samples revealed a high concordance between single nucleotide variants and gene fusions whereas other complex structural variants were not as consistent. The presence of gene fusions representing the major driver mutations at similar allelic frequencies in PDX samples compared to primary samples and over multiple passages confirms the utility of PDX models for preclinical drug testing. Characterization and tracking of these novel cryptic fusions and exonal variants in PDX models is critical in assessing response to potential new therapies.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.12
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• pp.6087-6091
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• 2012

Context: Patients diagnosed with a cancer have a life time risk of developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. Of late the detection of new primary has increased mainly due to refinement in both diagnostic and treatment modalities. Cancer victims are surviving longer and thus are more likely to develop a new metachronous malignancy. Aims: To report our observed trend of increase in prevalence of both synchronous and metachronous second malignant neoplasms among cancer victims and to review the relevant literature. Settings and Design: A hospital based retrospective collection of prospective data of patients diagnosed with second denovo malignancy. Materials and Method: The study was conducted over a 5 year period from July 2008 to June 2012. All patients diagnosed with a histologically proven second malignancy as per Warren Gate's criteria were included. Various details regarding sex, age at presentation, synchronous or metachronous, treatment and outcome were recorded. Conclusions: The occurrence of multiple primary malignancies is not rare. Awareness of the possibility alerts the clinician in evaluation of patients with a known malignancy presenting with unusual sites of metastasis. Individualizing the treatment according to the stages of the primaries will result in durable cancer control particularly in synchronous double malignancy.

• Radiation Oncology Journal
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• v.2 no.1
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• pp.59-69
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• 1984

Guidelines for the optimal management of patients with cervical cancerous nodes from an unknown primary site, has not been yet settled. However. radical treatment has been advocated employing either a surgery, or radiotherapy, or a combination of the two in relation to the location, stage and histologic features of the nodes in the neck. Of 43 patients who presented with 'Cervical metastases from an unknown primary' since 1971, $31.2\%$ survived 3 years after adequate management. Combined modality with surgery and radiation showed more favorable treatment results: in local control rate, 3 year survival rates and the subsequent appearances of the contralateral side of neck node through the retrospective analysis. In 11 cases, the primary tumors became apparent later, carcinoma of the hypopharynx, being the most frequent site, rather than the nasopharynx.