• Journal of the Korean Society for Marine Environment & Energy
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• v.1 no.2
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• pp.96-108
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• 1998

The management of water quality and fishery resources with a major environmental problem in eutrophic coastal sea is studied. The numerical experiments using the water-sediment quality model (WSQM) were carried out for the management of water quality at the Seto Inland Sea in Japan. The results of long-term water quality simulation showed responses of seawater quality to input loads to vary in different localities. A formula roughly forecasting water qualify to estimate the effect of loading abatement was proposed. The simulation for the improvement of seawater quality showed the abatements of nutrient loads such as total phosphorus (TP) and total nitrogen (TN) as well as organic loads such as chemical oxygen demand (COD) to be peformed in the eastern Seto Inland Sea from Bisan Seto to Osaka Bay. On the other hand, it is indicated that the increase of loading leads to the increase of primary production. while not straightly to the increase of fish production for the catch of fisheries.

• Journal of Pharmaceutical Investigation
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• v.35 no.1
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• pp.33-38
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• 2005

Recently increasing attention has been focused on solid lipid nanoparticles (SLN) as a parenteral drug carrier due to its numerous advantages that can come from both polymeric particle and fat emulsions, together with the possibility of controlled release and increasing drug stability. Lipophilic drugs such as paclitaxel, cyclosporin A, and all-trans retinoic acid have been successfully entrapped in SLN but the incorporation of hydrophilic drugs in SLN is very limited because of their very low affinity to the lipid. Therefore, as a new approach to improve the loading of hydrophilic drugs, a w/o/w emulsion technique has been developed. The primary objective of the current study was to improve the loading efficiency of a model hydrophilic drug, glycine (Log P = -3.44) into SLN. The proposed preparation process is as follows: A heated aqueous phase consisting of 0.1 ml of glycine solution in water (100 mg/ml), and poloxamer 188 (5 mg) were then added to a molten oil phase containing precirol (100 mg) and lecithin (5 mg). This mixture was dispersed by sonicator, leading to a w/o emulsion. A double emulsion (w/o/w) was formed after the addition of 2% poloxamer solution to the above dispersed system. After cooling the double emulsion, solid lipid nanosuspensions were successfully formed. The lipid nanoparticles had the mean particle size of 441.25 nm, and the average zeta potential of -20.98 mV. The drug loading efficiency was measured to be 8.54% and the drug loading amount was measured to be 0.92%. The w/o/w emulsion method showed an increased loading efficiency compared to conventional o/w emulsion method.

• The Journal of Korean Academy of Prosthodontics
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• v.62 no.2
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• pp.131-139
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• 2024

In a edentulous patient, various methods can be employed for prosthetic treatment using implants, such as implant-supported fixed prostheses, overdentures, hybrid prostheses, and implant assisted removable partial denture. In this case, in a patient with moderate to severe chronic periodontitis requiring full arch extractions, implants were strategically placed using computer-guided surgery. In the maxilla, due to inadequate bone quality and quantity leading to insufficient initial stability, delayed loading was implemented, and interim prosthesis was used during the osseointegration period. In the mandible, stable initial stability was achieved, allowing for immediate loading to reduce patient discomfort. Primary stability is considered the most crucial factor for obtaining immediate loading, so a thorough clinical and radiological evaluation of the remaining alveolar bone quantity and quality must be conducted before surgery.

• Journal of the Society of Naval Architects of Korea
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• v.33 no.3
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• pp.66-80
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• 1996

Recently, HT steel has been widely used in structure, and this enables to reduce the plate thickness. To use the HT steel effectively for a ship hull, the plate thickness becomes thin so that plate buckling may take place. Therefore, precise assessment of the behaviour of plat above primary buckling load is important. The plate under the load, that is called, secondary buckling load may undergo abrupt changes in wave form after primary buckling. This is very important when the collapse strength of the whole structures is considered. From this point of view, this paper discusses secondary buckling behaviour of thin plate under inplane compressive loading. A elastic large deflection analysis of plates with initial imperfection is performed assuming uniaxial compression, respectively, and the influence of secondary buckling is investigated. It is known that square plate is not influenced by non-symmetrical deflection coefficient but influenced by symmetrical deflection coefficient. Also, it has been found that rectangular plate($\alpha$=a/b) is influenced by all deflection coefficient, and the reduction of inplane stiffness of the plate after primary buckling is continued.

• The Journal of Advanced Prosthodontics
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• v.10 no.3
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• pp.227-235
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• 2018

PURPOSE. Implant site preparation may be adjusted to achieve the maximum possible primary stability. The aim of this investigation was to study the relation among bone-to-implant contact at insertion, bone density, and implant primary stability intra-operatively measured by a torque-measuring implant motor, when implant sites were undersized or tapped. MATERIALS AND METHODS. Undersized (n=14), standard (n=13), and tapped (n=13) implant sites were prepared on 9 segments of bovine ribs. After measuring bone density using the implant motor, 40 implants were placed, and their primary stability assessed by measuring the integral of the torque-depth insertion curve. Bovine ribs were then processed histologically, the bone-to-implant contact measured and statistically correlated to bone density and the integral. RESULTS. Bone-to-implant contact and the integral of the torque-depth curve were significantly greater for undersized sites than tapped sites. Moreover, a correlation between bone to implant contact, the integral and bone density was found under all preparation conditions. The slope of the bone-to-implant/density and integral/density lines was significantly greater for undersized sites, while those corresponding to standard prepared and tapped sites did not differ significantly. CONCLUSION. The integral of the torque-depth curve provided reliable information about bone-to-implant contact and primary implant stability even in tapped or undersized sites. The linear relations found among the parameters suggests a connection between extent and modality of undersizing and the corresponding increase of the integral and, consequently, of primary stability. These results might help the physician determine the extent of undersizing needed to achieve the proper implant primary stability, according to the planned loading protocol.

• Journal of Periodontal and Implant Science
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• v.47 no.2
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• pp.106-115
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• 2017

Purpose: The possibility of immediate or early loading has become popular in implant dentistry. A prerequisite for the immediate or early loading of an implant prosthesis is the achievement of initial stability in the implant. Moreover, in response to clinicians' interest in verifying clinical stability to determine the optimal time point for functional loading, a non-invasive method to assess implant stability has been developed on the basis of resonance frequency analysis (RFA). The primary objective of this study was to monitor the stability of sandblasted, large-grit, and acid-etched (SLA) implants with different diameters during the early phases of healing by RFA. The secondary objective was to evaluate how the initial stability of implants varied depending on different surface modifications and other contributing factors. Methods: Thirty-five implants (25 SLA implants and 10 resorbable blasting media [RBM] implants) placed in 20 subjects were included. To measure implant stability, RFA was performed at baseline and at 1, 2, 3, 4, 6, and 10 weeks after surgery. Results: The longitudinal changes in the implant stability quotient (ISQ) values were similar for the SLA implants with different diameters and for the RBM implants. During the initial healing period, the ISQ decreased after installation and reached its lowest values at 1 week and 2 weeks, respectively. The mean ISQ values in the SLA implants were significantly higher in ${\varnothing}5.0mm$ implants than in ${\varnothing}4.0mm$ implants. Men showed a higher ISQ than women. Mandibular sites showed a higher ISQ than maxillary sites. Conclusions: All implants used in this study are suitable for immediate or early loading under appropriate indications. A wider diameter and SLA surface treatment of implants could improve the stability, if the implant is fixed with at least 30 Ncm of insertion torque.

• Fire Science and Engineering
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• v.23 no.2
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• pp.27-35
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• 2009

In this study, the fire resistance performance of a simple support composite beam, which was sprayed with fire protection coatings, was evaluated. Primary valuables of the study are loading and unloading, shape of composite beam and metal lath of the web. The thickness of the fire protection coating to the three hour resistance is 40mm, but the fire resistance test was performed with 25mm coatings. The test result showed that TSC composit beams with 25mm fire protection coatings can resist on fire for three hours at the both loading and unloading tests. Average and maximum temperatures were less than $250^{\circ}C$ and $310^{\circ}C$ respectively, compared with the standard temperatures for fire resistance on the loading and unloading tests.

• International Journal of Concrete Structures and Materials
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• v.1 no.1
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• pp.29-36
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• 2007

The purpose of this paper is the assessment of the capacity of the reinforced concrete (RC) elements of an arch bridge when they are subjected to contact and near-contact explosive charges of various amounts, and the estimation of the critical charges for these components. The bridge considered is the Tenza Viaduct, a decommissioned structure south of Naples, Italy. Its primary elements, deck, piers and arches were analyzed. The evaluation was accomplished via numerical analyses that made possible to obtain the elements dynamic response when they are exposed to blast loading conditions. To evaluate the member's capacities, failure criteria for deck, piers and arches were proposed based on concrete damage parameters. Additionally, curves relating the explosive charge to the residual capacity and to damage level of the elements were also developed. The results of this work were taken into account to investigate the progressive collapse of the global structure.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.169-172
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• 2008

Longitudinal elongation develops in reinforced concrete beams that exhibit flexural yielding during cyclic loading. The longitudinal elongation can decrease the shear strength and deformation capacity of the beams. In the present study, nonlinear truss model analysis was performed to study the elongation mechanism of reinforced concrete beams. The results showed that residual tensile plastic strain of the longitudinal reinforcing bar in the plastic hinge is the primary factor causing the member elongation, and that the shear-force transfer mechanism of diagonal concrete struts has a substantial effect on the magnitude of the elongation. Based on the analysis results, a simplified method for evaluating member elongation was developed. The proposed method was applied to test specimens with various design parameters and loading conditions..

• Structural Engineering and Mechanics
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• v.50 no.2
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• pp.151-161
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• 2014

In this paper, fuel tank of the locomotive ER 24 has been studied. Firstly the behavior of fuel and air during the braking time has been investigated by using a two-phase model. Then, the distribution of pressure on the surface of baffles caused by sloshing has been extracted. Also, the fuel tank has been modeled and analyzed using Finite Element Method (FEM) considering loading conditions suggested by the DIN EN 12663 standard and real boundary conditions. In each loading condition, high stressed areas have been identified. By comparing the distribution of pressure caused by sloshing phenomena and suggested loading conditions, optimization of the tank has been taken into consideration. Moreover, internal baffles have been investigated and by modifying their geometric properties, search of the design space has been done to reach the optimal tank. Then, in order to reduce the mass and manufacturing cost of the fuel tank, Non-dominated Sorting Genetic Algorithm (NSGA-II) and Artificial Neural Networks (ANNs) have been employed. It is shown that compared to the primary design, the optimized fuel tank not only provides the safety conditions, but also reduces mass and manufacturing cost by %39 and %73, respectively.