• 제목/요약/키워드: primary exposure

검색결과 468건 처리시간 0.031초

망간이 백서 두개관세포에 미치는 영향 (Effect of Manganese on primary rat calvarial cell)

  • 김지은;김영준;정현주;김옥수
    • Journal of Periodontal and Implant Science
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    • 제34권2호
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    • pp.357-366
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    • 2004
  • Chronic exposure to high levels of manganese leads a pronounce and debilitating disorder known as manganism. Research on the toxic manifestation of manganese have focused primarily on its neurological effects because exposure to high levels of the metal produces a distinct and irreversible extrapyramidal dysfunction resembling the dystonic movements associated with Parkinson's physiological and biochemical systems in the body. The purpose of this study was to evaluate the effect of manganeses on primary rat calvarial cell growth and toxicity. The experimental groups were in concentration of 0, 10, 30, 60, 100, 300 ${\mu}M$. Cell activity was assessed at day 1 and day 3 using a fluorescent molecular probe. Cell proliferation was evaluated at day 1 and day 3 by MTT assay. The amount of total protein synthesis was measured at day 3 and day 7. The results were as follows: The proliferation of primary rat calvarial cells were inhibited by $MnCl_2$ in the concentration exceeding $100{\mu}M$. The primary rat calvarial cells treated with $MnCl_2$ showed similar protein synthesis to the control group except in 100 ${\mu}M$. These result suggest that manganese suppress the viability and protein synthesis of primary rat calvarial cells in concentration exceeding $100{\mu}M$.

복식에 표현된 노출 (Exposure Expressed in Dress)

  • 정연자
    • 한국의상디자인학회지
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    • 제1권1호
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    • pp.91-107
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    • 1999
  • The primary purpose of this study is to inquire into the characteristic of exposure presented in fashion, identify the correct concept of exposure from an aesthetic perspective, and grasp the contemporary meaning of exposure presented in fashion. As a result of study, the following findings were obtained: First, the surrealist style of fashion exhibited representations such as the relocation of the partial details, the harmonization of the natural and the artificial, the emphasis or expansion of each part of the body, and the like. It used highlighted the genital region with ornamentations or used the technique of paradoxically exposing the part of the body always covered. And it exbibited the paradoxical relationship of exposure and concealment by exposing the concealed part of the human body. Second, the post-modern style showed the complicated phenomenon that the values of several meanings such as the historic, the folk, and the like appeared in its fashion. It shares in spatiotemporal eclecticism, pluralistic characteristics and the like found in the post-modern culture. Third, the deconstructive style gets rid of the distinction between the external space and the private space by translating underwears into outer garments. It destroys clothing by tearing or perforating clothing whereby it represents the poor image. Coupled with women‘s psychology of exposure and the new generation’s way of thinking indifferent to others‘ eyes, this fashion of deconstruction occupies the great current of fashion. Deconstructive fashion gets away with the rule of ‘having to wear clothing to suit TPO(Time, Place and Occasion), the traditional norm of wearing clothing.

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Identity-based Provable Data Possession for Multicloud Storage with Parallel Key-Insulation

  • Nithya, S. Mary V.;Rhymend Uthariaraj, V.
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제15권9호
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    • pp.3322-3347
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    • 2021
  • Cloud Storage is the primary component of many businesses on cloud. Majority of the enterprises today are adopting a multicloud strategy to keep away from vendor lock-in and to optimize cost. Auditing schemes are used to ascertain the integrity of cloud data. Of these schemes, only the Provable Data Possession schemes (PDP) are resilient to key-exposure. These PDP schemes are devised using Public Key Infrastructure (PKI-) based cryptography, Identity-based cryptography, etc. PKI-based systems suffer from certificate-related communication/computational complexities. The Identity-based schemes deal with the exposure of only the auditing secret key (audit key). But with the exposure of both the audit key and the secret key used to update the audit key, the auditing process itself becomes a complete failure. So, an Identity-based PDP scheme with Parallel Key-Insulation is proposed for multiple cloud storage. It reduces the risk of exposure of both the audit key and the secret key used to update the audit key. It preserves the data privacy from the Third Party Auditor, secure against malicious Cloud Service Providers and facilitates batch auditing. The resilience to key-exposure is proved using the CDH assumption. Compared to the existing Identity-based multicloud schemes, it is efficient in integrity verification.

1차 의료기관에 내원한 환자의 방사선피폭 인지도에 관한 연구 (A Study on Perception by examinees of the Primary Health Care institutions about Exposure to Radioactivity)

  • 여진동;전병규
    • 한국방사선학회논문지
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    • 제9권6호
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    • pp.381-392
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    • 2015
  • 본 연구는 1차 의료기관 내원 환자를 대상으로 진단용 방사선 검사 시 방사선피폭 인식에 대한 관련요인을 분석하여 방사선피폭 인식의 변화를 위한 교육 자료를 만드는데 기초자료를 제공하기 위해 시도하였다. 방사선 장치 중 가장 방사선 피폭을 가장 많이 받는 검사에 대해서는 전체 66.7%로 CT가 가장 높았으며, 방사선 검사 시 피폭에 가장 민감한 부위에 대해서는 생식선 56.2% 가장 많았고, 방사선에 대한 정보 파악은 전체 25.9%가 TV나 신문을 통해 습득하는 것이 가장 많았다. 방사선 인식도, 방사선 유해성, 방사선 검사 시 심리상태, 방사선 피폭방지, 방사선 필요성에 대해서는 성 별간 남자가 더 높게 나타났으며, 통계학적으로는 유의한 차이가 있었다. 본 연구를 통해서 환자들로 하여금 방사선피폭에 대하여 올바르게 인식을 할 수 있도록 교육프로그램의 개발이 시급하며, 방사선사들에게는 환자의 피폭선량을 경감을 위한 세심한 배려가 필요하다고 하겠다. 또한 환자들은 방사선에 대해서 올바르게 인식하는 것이 촬영 시 불안감과 방사선피폭을 줄일 수 있을 것이다.

Identification of Immune Responsive Genes on Benzene, Toluene and o-Xylene in Jurkat Cells Using 35 k Human Oligomicroarray

  • Sarma, Sailendra Nath;Kim, Youn-Jung;Jeon, Hee-Kyung;Ryu, Jae-Chun
    • Molecular & Cellular Toxicology
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    • 제2권4호
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    • pp.229-235
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    • 2006
  • Volatile organic compounds (VOCs) are a major component of urban air pollution. It is documented that low exposure levels of VOCs induce alterations in immune reactivity resulting in a subsequent higher risk for the development of allergic reactivity and asthma. Despite these facts, there are few reports on the affected primary target and the underlying effective causal mechanisms. So in this study, to better understand the risk of BTX (benzene, toluene and o-xylene) which are the major VOCs and to identify novel biomarkers on immune response to these VOCs exposure in human T lymphocytes, we performed the toxicogenomic study by analyzing of gene expression profiles using 35 k human oligo-microarray. BTX generated specific gene expression patterns in Jurkat cell line. By clustering analysis, we identified some genes as potential markers on immuno-modulating effects of BTX. Four genes of these, HLA-DOA, ITGB2, HMGA2 and 5TAT4 were the most significantly affected by BTX exposure. Thus, this study suggests that these differentially expressed immune genes may play an important role in the pathogenesis on BTX exposure and have significant potential as novel biomarkers of exposure, susceptibility and response to BTC.

Women's Body Exposure in Leisure Wear during the 1930s -Focused on Bathing Suits, Shorts, and Halters-

  • Lee, Yhe-Young;Farrell-Beck, Jane
    • 한국의류학회지
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    • 제36권6호
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    • pp.592-600
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    • 2012
  • Social reactions to body exposure in American leisure wear (bathing suits, shorts, and halters) in the 1930s were analyzed to provide an understanding of the process of adopting more abbreviated and less-occasion specific styles of garments in women's fashion. The research questions were as follow: How did women expose their bodies in leisure wear during the 1930s? How did the social reaction to women's body exposure in leisure wear change throughout the 1930s? How did the body exposure in women's leisure wear play a significant role in the history of women's fashion? Primary sources were collected from issues of The New York Times published in the 1930s. Topics including dress, fashion, ethics, social ethics, and sexual ethics, were reviewed in The New York Times indices. The findings were analyzed and interpreted with reference to secondary sources that included books and research papers. The results showed that the body exposure of the styles as well as the place where these styles were worn was a public issue. Women were criticized and regulated for body exposure as well as for wearing bathing suits, shorts, and halters on the streets. However, the social regulations that restricted bathing suit styles almost disappeared by the end of the decade. This represented the change of social expectations toward body exposure in the 1930s. In addition, reports of laws that forbade the wearing of bathing suits, halters, and shorts outside of beaches, pools, and parks indicated women's increased attempts to expose their bodies in public places. However, reactions to women's body exposure in leisure wear changed to accept more flexibility in the social customs throughout the decade. These phenomena were a partial step toward the popularization of less occasion-specific styles - sportswear - that took place in the 20th century.

Effects of Ultraviolet-B Radiation on Growth and Photosynthesis in Cucumber Primary Leaves

  • Kim, Hyo-Jin;Kim, Tae-Yun;Hong, Jung-Hee
    • 한국환경과학회지
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    • 제15권12호
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    • pp.1093-1101
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    • 2006
  • In the present study we studied the growth, photosynthetic traits and protective mechanisms against oxidative stress in the primary loaves of cucumber (Cucumis sativus L.) seedlings with or without UV-B treatment. Cucumber seedings were irradiated with UV-B for 10 days in environment-controlled growth chambers. The primary leaves irradiated with UV-B showed reduction in leaf length and decreased biomass production. The reduced biomass production seemed to be due to a negative effect of UV-B radiation on the photosynthetic process. Changes in chemical properties of leaf, such as chi a/b ratio affected photosynthesis. UV-B significantly affected chl b content compared with chi a in the light harvesting complex resulting reduced photosynthetic activity Fv/Fm decreased with an UV-B stress, suggesting that the photosynthetic apparatus, and particularly, PS II was damaged under UV-B stress. Malondialdehyde(MDA) concentration which represents the state of membrane lipid peroxidation Increased significantly under UV-B stress confirming an oxidative stress. UV-B exposure with SA solution(0.1-1.0 mM) can partially ameliorated some of the detrimental effects of UV-B stress. Leaf injuries including loss of chlorophyll and decreased ratio of Fv/Fm were reduced with combined application of UV-B and SA. ABA and JA showed similar mode of action in physiological effects on photosynthetic activities though the levels were lower than those from SA treated plants. Chloroplast ultrastructure was also affected by UV-B exposure. The thickness of leaf tissue components decreased and the number of grana and thylakoids was reduced in chloroplast applied UV-B or SA alone. At combined stress granal and stromal thylakoids were less affected. The leaves under combined stress acquired a significant tolerance to oxidative stress. From these results, it can be suggested that SA may have involved a protective role against UV-B induced oxidative damage.

Exposure Assessment Study on Lithium-Ion Battery Fire in Explosion Test Room in Battery Testing Facility

  • Mi Sung Jo;Hoi Pin Kim;Boo Wook Kim;Richard C. Pleus;Elaine M. Faustman;Il Je Yu
    • Safety and Health at Work
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    • 제15권1호
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    • pp.114-117
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    • 2024
  • A lithium-ion battery is a rechargeable battery that uses the reversible reduction of lithium ions to store energy and is the predominant battery type in many industrial and consumer electronics. The lithium-ion batteries are essential to ensure they operate safely. We conducted an exposure assessment five days after a fire in a battery-testing facility. We assessed some of the potentially hazardous materials after a lithium-ion battery fire.We sampled total suspended particles, hydrogen fluoride, and lithium with real-time monitoring of particulate matter (PM) 1, 2.5, and 10 micrometers (㎛). The area sampling results indicated that primary potential hazardous materials such as dust, hydrogen fluoride, and lithium were below the recommended limits suggested by the Korean Ministry of Labor and the American Conference of Governmental Industrial Hygienists Threshold Limit Values. Based on our assessment, workers were allowed to return to work.

소음에 대한 특수건강진단 및 작업환경측정 결과 분석 (Analysis of Noise Special Medical Examination and Work Environment Monitoring Results)

  • 김갑배;박해동
    • 한국소음진동공학회논문집
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    • 제25권1호
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    • pp.5-12
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    • 2015
  • According to the analysis of special medical examination and work environment monitoring data, the rate of C1 and D1 on noise hazard exceeded 90 % among those of total hazardous factors. The rate of company exceeding noise exposure limit was also more than 90 %. The analysis result shows that main ages diagnosed with C1 and D1 was age of 50s. The majority scale company having workers diagnosed with C1 and D1 was the companies employing 5~49 workers. Types of industries which have a large number of companies exceeding noise exposure limit were automobile and trailer manufacturing, metal processing industry and primary metal manufacturing. A large number of work processes exceeding noise exposure limit were forming and processing work, cutting and bending work and grinding. To reduce the number of company exceeding noise exposure limit, the reduction counterplan should be focused on the type of industry and the work process which exceeded noise exposure limit frequently. However, the reduction counterplan is preemptively necessary to the type of industry and the work process which exceeded noise exposure limit consecutively if the purpose of reduction counterplan is not to merely reduce the number of company exceeding noise exposure limit but to abate workers' suffering from noise.

Effect of the Heat-exposure on Peripheral Sudomotor Activity Including the Density of Active Sweat Glands and Single Sweat Gland Output

  • Lee, Jeong-Beom;Kim, Tae-Wook;Shin, Young-Oh;Min, Young-Ki;Yang, Hun-Mo
    • The Korean Journal of Physiology and Pharmacology
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    • 제14권5호
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    • pp.273-278
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    • 2010
  • Tropical inhabitants are able to tolerate heat through permanent residence in hot and often humid tropical climates. The goal of this study was to clarify the peripheral mechanisms involved in thermal sweating pre and post exposure (heat-acclimatization over 10 days) by studying the sweating responses to acetylcholine (ACh), a primary neurotransmitter of sudomotor activity, in healthy subjects (n=12). Ten percent ACh was administered on the inner forearm skin for iontophoresis. Quantitative sudomotor axon reflex testing, after iontophoresis (2 mA for 5 min) with ACH, was performed to determine directly activated (DIR) and axon reflex-mediated (AXR) sweating during ACh iontophoresis. The sweat rate, activated sweat gland density, sweat gland output per single gland activated, as well as oral and skin temperature changes were measured. The post exposure activity had a short onset time (p<0.01), higher active sweat rate [(AXR (p<0.001) and DIR (p<0.001)], higher sweat output per gland (p<0.001) and higher transepidermal water loss (p<0.001) compared to the pre-exposure measurements. The activated sweat rate in the sudomotor activity increased the output for post-exposure compared to the pre-exposure measurements. The results suggested that post-exposure activity showed a higher active sweat gland output due to the combination of a higher AXR (DIR) sweat rate and a shorter onset time. Therefore, higher sudomotor responses to ACh receptors indicate accelerated sympathetic nerve responsiveness to ACh sensitivity by exposure to environmental conditions.