• Journal of Dairy Science and Biotechnology
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• v.28 no.2
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• pp.13-18
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• 2010

Electron Spin Resonance (ESR) spectroscopy has been used to detect the presence of radiation-induced free radicals in biological samples since the mid 1950s and to irradiate foods containing cellulose, crystalline sugar, and bone. Therefore, we analyzed the ESR spectrum of irradiated infant formula and its ingredients in this study. Samples were irradiated with 2 different radiation sources of $^{60}Co$ gamma rays and electron beams (EBs), and the absorbed doses were 0, 1, 3, 5, and 7 kGy. ESR measurements were performed under normal atmospheric conditions using a JEOL JES-FA100 spectrometer equipped with an X-band bridge. Irradiated infant formula showed anunsymmetrical spectrum ($g_1$=2.0050, $g_2$=2.0006); in contrast, non-irradiated samples showed asymmetrical spectrum. The ingredients of irradiated samples showed a multi-component ESR signal in glucose and lactose and a singlet-type spectrum in milk powder (g=2.0050). $R^2$ of the dose-response curve showed a fine linearity of over 0.95 across the entire sample. We also compared the spectra of identical samples irradiated with $^{60}Co$ gamma rays and EBs, because EBs can be used for food irradiation in foreign countries, although this is not permitted in Korea. However, we could not find any significant differences according to the types of radiation source. Thus, ESR spectroscopy can be used to detect irradiated infant formula and several types of primary ingredients in this formula.

• The Journal of Korean Academy of Prosthodontics
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• v.43 no.2
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• pp.264-279
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• 2005

Statement of problem. Intraoral corrosion not only affects the esthetic and function of metallic dental restoration, but also has biologic consequences as well. Therefore, corrosion is considered a primary factor when choosing the dental alloy and laboratory technique. Purpose. The objective of this study was to compare the effects of solder and laser weld on corrosion Material and methods. Test specimens were made of 2 types of gold alloys, Co-Cr and Ni-Cr alloy and fabricated 3 methods, respectively: as cast, solder, and laser weld. For the analysis of corroding properties, potentiodynamic polarization test and immersion test conducted. The potentiodynamic polarization scan curve were recorded in 0.9% NaCl solution(pH 7) using Potentiostat/Galyanostat Model 273A. All specimens were exposed to 0.9% NaCl solution(pH 2.3) during 14 days. Elemental release into corrosive solution was measured by atomic emission spectrometry Differences in corrosion potential and mass release were determined using ANOVA. Results and conclusion. Through analyses of the data, following results were obtained. 1. In Pontor MPF and Wiron 99, corrosion potential of the solder group was statistically lower than as cast and laser weld group (p<0.05) , but there was no difference between corrosion potential of solder group and laser weld group in Pontor MPF and no differences between as cast and laser weld group (p>0.05). In Jel-Bios 10 and Wirobond, there was no difference of corrosion potential according to joining methods(p>0.05). 2. In all tested alloys, the amount of released metallic ion was greatest in the solder group(p<0.05). There was no difference between as cast group and laser weld group in Jel-Bios 10 and Wirobond(p>0.05). 3. In scanning electron microscopic examination. except soldered Wiron 99 specimens, it is impossible to discriminate the corrosive property of solder and laser weld. 4. Under the this experimental circumstances, laser weld appears superior to the solder when corrosion is considered.

• Korean Journal of Agricultural Science
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• v.10 no.1
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• pp.110-117
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• 1983

This study was conducted to investigate the influence of load increment ratio on the secondary consolidation for the marine clay at Asan bay by the hyperbola method. The results were summarized as follow: 1. Calculated secondary consolidation by the hyperbola method was slightly less than the value of Casagrande's log t method, but the difference was very little, and the secondary consolidation could be easily calculated by the hyperbola method even if load increment ratio was small. 2. The secondary consolidation ratio was increased with the decrement of load increment ratio, and the creep phenomenon of the settlement curve occurred under the condition of small load increment ratio seemed to be caused by the secondary consolidation. 3. The secondary consolidation ratio occurred during the primary consolidation was irregular in the overconsolidated range, but it was increased with the decrement of load increment ratio in the normally consolidated range. 4. The coefficient of secondary consolidation was increased with the increment of the consolidation load, made a point of the inflection near preconsolidation. And the coefficient of secondary consolidation was decreased from consolidation load $2kg/cm^2$, showed independent of load increment ratio. 5. The coefficient of secondary consolidation was showed in proportion to compression index.

• Journal of Life Science
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• v.26 no.8
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• pp.921-927
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• 2016

Postprandial hyperglycemia is an early defect of type 2 diabetes and one of primary anti-diabetic targets. The alpha-glucosidase inhibitors regulate postprandial hyperglycemia by impeding the rate of carbohydrate (such as starch) digestion in the small intestine. This study was designed to investigate the inhibitory actions of mulberry fruit extract (MFE) on α-glucosidase and α-amylase activities, and its alleviating effect on postprandial hyperglycemia activities in vitro and in vivo. Male four-week old ICR mice and streptozotocin (STZ)-induced diabetic mice were treated with mulberry fruit extract. MFE showed strong inhibitory effects against α-glucosidase and α-amylase activities, with half-maximal inhibitory concentration (IC₅₀) values of 0.16 and 0.14 mg/ml, respectively, and was more effective than acarbose, which was used as a positive control. The increase in postprandial blood glucose levels was more significantly attenuated in the MFE-administered group mice than in the control group mice of both STZ-induced diabetic and normal mice. Moreover, the area under the glucose response curve significantly decreased following MFE administration in diabetic mice. These results indicate that MFE may be a potent inhibitor of α-glucosidase and α-amylase, and helpful in suppressing postprandial hyperglycemia in diabetic mice. The mulberry fruit extracts may be considered as a potential candidate for the management of diabetes.

• Korean Journal of Weed Science
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• v.13 no.1
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• pp.62-70
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• 1993

There was intraspecific variation in Echinochloa crus-galli var, crus-galli in response to quinclorac, showing that plan height and dry weight of a locally collected barnyardgrass(Chinjupi) from Chinju were 90.5 and 37.8% of the untreated control, while those of a locally collected one(Iripi) from Iri showed 19.1 and 14.4%, respectively. The normal distribution curve was obtained from frequency distribution of 89 rice cultivars as affected by the application rates of quinclorac at 30, 300, and 3,000g ai/ha. Protein patterns(SDS-PAGE) of two barnyardgrasses belonging to E, crus-galli var. crus-galli such as Iripi and Chinjupi were not affected by the quinclorac application, indicating that inhibition of enzyme and/or protein biosynthesis seems to be not the primary action target of quinclorac. Electronmicroscopic observation on the injured leaf of Iripi which is considered as a susceptible one showed prominent membrane disruption. Chuchungbyeo(rice variety) resulted in a greater inhibition of tomato growth than those from Chinjupi or Iripi, indicating a great amount of quinclorac discharged from rice root, Chinjupi which is relatively tolerant to quinclorac than Iripi, discharged more quinclorac causing a greater inhibition of tomato growth.

• Journal of the Korean Society of Radiology
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• v.10 no.3
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• pp.187-193
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• 2016

In this study, we performed the carotid artery ultrasound targeting 140 subjects who have conducted to evaluate the changes in intima-media thickness(IMT) and plaque correlated with the presence or absence of a hematological test of the carotid artery. Considering that the IMT thickness more than 1mm is abnormal based on the carotid artery ultrasound to assess the presence or absence of plaque, and examined the correlation by classifying the blood lipid value and the fasting blood glucose level through the serum test. Consequently, the fasting blood glucose level is being analyzed as independent predictors of causing dental plaque(p=0.033), cut off value was determined as 126 mg/dL(sensitivity 56.25%, specificity 68.38%) in ROC curve analysis. Furthermore, the odds ratio appeared 1.01 times the value in the Logistic regression. Therefore, it seemed that the necessity to prospective studies in a number of subjects are considered, and also taking into account a number of blood test values along with the sonography of the carotid artery as a valuable part for effective primary prevention and follow-up observation of the cardiac and brain vascular disease is highly recommended.

• Clinical and Experimental Emergency Medicine
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• v.5 no.4
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• pp.219-229
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• 2018

Objective We compared the predictive value of the National Early Warning Score+Lactate (NEWS+L) score with those of other parameters such as the pre-endoscopic Rockall score (PERS), Glasgow-Blatchford score (GBS), and albumin, international normalized ratio, altered mental status, systolic blood pressure, age older than 65 years score (AIMS65) among patients with upper gastrointestinal bleeding (UGIB). Methods We conducted a retrospective study of patients with UGIB during 2 consecutive years. The primary outcome was the composite of in-hospital death, intensive care unit admission, and the need for ${\geq}5$ packs of red blood cell transfusion within 24 hours. Results Among 530 included patients, the composite outcome occurred in 59 patients (19 inhospital deaths, 13 intensive care unit admissions, and 40 transfusions of ${\geq}5$ packs of red blood cells within 24 hours). The area under the receiver operating characteristic curve of the NEWS+L score for the composite outcome was 0.76 (95% confidence interval, 0.70 to 0.82), which demonstrated a significant difference compared to PERS (0.66, 0.59-0.73, P=0.004), but not to GBS (0.70, 0.64-0.77, P=0.141) and AIMS65 (0.76, 0.70-0.83, P=0.999). The sensitivities of NEWS+L scores of 3 (n=34, 6.4%), 4 (n=92, 17.4%), and 5 (n=171, 32.3%) were 100%, 98.3%, and 96.6%, respectively, while the sensitivity of an AIMS65 score of 0 (n=159, 30.0%) was 91.5%. Conclusion The NEWS+L score showed better discriminative performance than the PERS and comparable discriminative performance to the GBS and AIMS65. The NEWS+L score may be used to identify low-risk patients among patients with UGIB.

• Clinical and Experimental Pediatrics
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• v.63 no.11
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• pp.438-446
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• 2020

Background: Most developmental screening tools in Korea are adopted from foreign tests. To ensure efficient screening of infants and children in Korea, a nationwide screening tool with high reliability and validity is needed. Purpose: This study aimed to independently develop, standardize, and validate the Korean Developmental Screening Test for Infants and Children (K-DST) for screening infants and children for neurodevelopmental disorders in Korea. Methods: The standardization and validation conducted in 2012-2014 of 3,284 subjects (4-71 months of age) resulted in the first edition of the K-DST. The restandardization and revalidation performed in 2015-2016 of 3.06 million attendees of the National Health Screening Program for Infants and Children resulted in the revised K-DST. We analyzed inter-item consistency and test-retest reliability for the reliability analysis. Regarding the validation of K-DST, we examined the construct validity, sensitivity and specificity, receiver operating characteristic curve analysis, and a criterion-related validity analysis. Results: We ultimately selected 8 questions in 6 developmental domains. For most age groups and each domain, internal consistency was 0.73-0.93 and test-retest reliability was 0.77-0.88. The revised K-DST had high discriminatory ability with a sensitivity of 0.833 and specificity of 0.979. The test supported construct validity by distinguishing between normal and neurodevelopmentally delayed groups. The language and cognition domain of the revised K-DST was highly correlated with the K-Bayley Scales of Infant Development-II's Mental Age Quotient (r=0.766, 0.739), while the gross and fine motor domains were highly correlated with Motor Age Quotient (r=0.695, 0.668), respectively. The Verbal Intelligence Quotient of Korean Wechsler Preschool and Primary Scales of Intelligence was highly correlated with the K-DST cognition and language domains (r=0.701, 0.770), as was the performance intelligence quotient with the fine motor domain (r=0.700). Conclusion: The K-DST is reliable and valid, suggesting its good potential as an effective screening tool for infants and children with neurodevelopmental disorders in Korea.

• Journal of Dental Anesthesia and Pain Medicine
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• v.22 no.2
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• pp.145-153
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• 2022

Background: Postoperative analgesia (POA) is an important determinant of successful treatment. Dexmedetomidine (DEX) has recently gained attention as a promising adjuvant to local anesthetics (LA). The present study aimed to evaluate the efficacy and safety of levobupivacaine (LB) as an adjuvant during inferior alveolar nerve block (IANB) in the extraction of lower impacted third molars (LITM). Methods: A prospective, randomized, placebo-controlled, triple-blind, parallel-arm, and clinical study was performed on 50 systemically healthy participants who required removal of an asymptomatic LITM. Using a 1:1 distribution, the participants were randomized into two groups (n = 25). Group L (control group) received 1.8 mL of 0.5% LB and 0.2 mL normal saline (placebo) and Group D (study group) received a blend of 1.8 mL of 0.5% LB and 0.2 mL (20 ㎍) DEX. The primary outcome variable was the duration of POA and hemodynamic stability, and the secondary variable was the total number of analgesics required postoperatively for up to 72 h. The participants were requested to record the time of rescue analgesic use and the total number of rescue analgesics taken. The area under the curve was plotted for the total number of analgesics administered. The pain was evaluated using the visual analog scale. Data analysis was performed using paired students and unpaired t-test, Mann-Whitney U test, Chi-square test, and receiver operating characteristic analysis. Statistical significance was set at P < 0.05. Results: The latency, profoundness of anesthesia, and duration of POA were statistically significant (P < 0.05). The differences between mean pain scores at 6, 12, 24, 48, and 72 h were found to be significant (each P = 0.0001). Fewer analgesics were required by participants in group D (2.12 ± 0.33) than in L (4.04 ± 0.67), with a significant difference (P = 0.0001). Conclusion: Perineurally administered LA with DEX is a safe, effective, and therapeutic approach for improving latency, providing profound POA, and reducing the need for postoperative analgesia.

• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.661-672
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• 2022

After the outbreak of the SARS-CoV2 virus that causes COVID-19, it spreads around the world with the number of infections and deaths rising rapidly caused a shortage of medical resources. As a way to solve this problem, chest X-ray diagnosis using Artificial Intelligence(AI) received attention as a primary diagnostic method. The purpose of this study is to comprehensively analyze the detection of COVID-19 via AI. To achieve this purpose, 292 studies were collected through a series of Classification methods. Based on these data, performance measurement information including Accuracy, Precision, Area Under Cover(AUC), Sensitivity, Specificity, F1-score, Recall, K-fold, Architecture and Class were analyzed. As a result, the average Accuracy, Precision, AUC, Sensitivity and Specificity were achieved as 95.2%, 94.81%, 94.01%, 93.5%, and 93.92%, respectively. Although the performance measurement information on a year-on-year basis gradually increased, furthermore, we conducted a study on the rate of change according to the number of Class and image data, the ratio of use of Architecture and about the K-fold. Currently, diagnosis of COVID-19 using AI has several problems to be used independently, however, it is expected that it will be sufficient to be used as a doctor's assistant.