• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3465-3470
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• 2014

Background: Previous studies have generated conflicting evidence regarding associations between family history and survival after gastric cancer surgery. In this study, we investigated this question using a meta-analysis. Materials and Methods: To identify relevant studies, PubMed and Embase databases were searched up to June 2013. Two reviewers independently assessed search results and data extraction of included studies. Hazard ratios (HRs) and 95% confidence intervals (CIs) for overall survival (OS) were calculated based on fixed- or random-effects models. Homogeneity of effects across studies was assessed using $x^2$ test statistics and quantified by $I^2$. Results: A total of five studies were selected according to the inclusion criteria. The total number of patients included was 2,030, which ranged from 145 to 598 per study. There was no significant difference in OS by family history of cancer (HR=0.83, 95%CIs=0.50-1.38), but subgroup analysis of patients with a first-degree family history of cancer (HR=0.74, 95%CIs=0.60-0.93) and gastric cancer family history (HR=0.56, 95%CIs=0.41-0.76) tended to show better OS in these patients. Conclusions: This meta-analysis suggests that a first-degree family history of cancer or gastric cancer family history is associated with better survival of gastric cancer patients after surgery, after a systematic review of five previous studies. These results can be applied by clinicians when counselling patients regarding their risk of death from gastric cancer. Further study is needed to investigate the underlying mechanism between family history and survival in gastric cancer patients.

• 환경생물
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• 제38권2호
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• pp.308-314
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• 2020

The Nannophya species in Korea was thought to consist of only Nannophya pygmaea. Previous studies on the species, including life history and development, conservation and restoration, habitat characteristics, genetic studies, distribution, behavior, and taxonomy have been conducted. However, a new Nannophya species, Nannophya koreana, was recently discovered in Korea. Moreover, this new species was found to inhabit both Korea and Japan. Thus, the previous studies should be reevaluated in relation to the new species, Nannophya koreana, and the latter should be treated as an endangered species worldwide given the current population instability.

• Clinical and Experimental Reproductive Medicine
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• 제16권1호
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• pp.81-91
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• 1989

It has been suggested that the prognosis for fertility of the infertile patients with healed pelvic tuberculosis is very poor. Total 60 patients(77 cycles) with previous history of pelvic tuberculosis who underwent IVF-ET from January 1988 to March 1989 at SNUH were classified into three groups according to the principal histopathological lesions : tuberculous endometritis group(N=20, 28 cycles), tuberculous salpingitis group(N=32, 37 cycles) and pelvic peritoneal tuberculosis group(N=8, 12 cycles). To evaluate the effects of previous pelvic tuberculous lesions on ovarian follicular growth and development in controlled ovarian hyperstimulation for IVF-ET and its final outcome, serum E2 levels on the day of hCG administration(Day 0) and the day after hCG administration(Day +1), the number of ovarian follicles with mean diamete ${\geqq}$ 12 mm on Day 0, the number of oocytes retrieved by transvaginal aspiration, and pregnancy rate per cycle were measured and compared with control group(N=123, 161 cycles). There were no significant differences in cancellation rate during controlled ovarian hyperstimulation, total dosage of FSH and hMG administrated, menstrual cycle date(MCD) of hCG injection, serum E2 levels, the number of ovarian follicles with mean diameter ${\geqq}$ 15 mm, and the number of oocytes retrieved between pelvic tuberculosis group and control group. But in pelvic tuberculosis group, the number of ovarian follicles with mean diameter 12-14 mm, total number of ovarian follicles(${\geqq}$ 12 mm), and pregnancy rate per cycle were significantly decreased. These data suggest that previous pelvic tuberculous lesions have no significant adverse effects on the ovarian response to gonadotropin stimulation. IVF-ET proved to be an useful treatment modality for infertile patients with previous history of pelvic tuberculosis in spite of its relatively lowered pregnancy rate.

• Journal of Korean Neurosurgical Society
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• 제44권6호
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• pp.405-408
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• 2008

GBM is the most common primary brain tumor, but intraventricular GBM is rare and only few cases have been reported in the literature. The authors report a case of 64-year-old man who had a remote history of previous periventricular intracerebral hemorrhage. Brain computed tomography (CT) and magnetic resonance (MR) imaging showed an intraventricular lesion with inhomogeneous enhancement, infiltrative borders and necrotic cyst, and obstructive hydrocephalus. The patient underwent surgical removal through transcortical route via the bottom of previous hemorrhage site and the final pathologic diagnosis was GBM. We present a rare case of an intraventricular GBM with detailed clinical course, radiological findings, and pathological findings, and the possible origin of this lesion is discussed.

• 대한한의학원전학회지
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• 제35권4호
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• pp.1-9
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• 2022

Objectives : This study aims to increase efficiency of the prescription similarity analysis method that uses drug composition ratio. Methods : The controlled experiment compared result generation time, generated data quantity, and accuracy of results between previous and new analysis method on the 12,598 formulas and 61 prescription groups. Results : The control group took 346 seconds on average and generated 768,478 results, while the test group took 24 seconds and generated 241,739 results. The test group adopted a selective calculation method that only used overlapping data between two formulas instead of analyzing all number of cases. It simplified the data processing process, reducing the quantity of data that is required to be processed, leading to better system speed, as fast as 14.47 times more than previous analysis method with equal results. Conclusions : Efficiency for similarity analysis could be improved by reducing data span and simplifying the calculation processes.

• Journal of Oral Medicine and Pain
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• 제26권2호
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• pp.133-146
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• 2001

This study was performed to predict the conservative treatment outcome of TMD patients by investigating the prognostic factors ; symptom duration, history of previous treatment, history of previous medication, history of trauma, disability of daily activity, severity of pain, noise, limitation of mouth opening(LOM) and maximum comfortable opening(MCO). Two hundreds and fifty-four subjects were selected for this study among the TMD patients who had visited the Dept. of Oral Medicine BNUH and been treated conservatively with medication, physical therapy, behavioral treatment, and splint therapy from 1991 to 2000. The subjects were divided into two groups improved or unimproved according to the treatment response following six months of conservative treatment. Those who showed less than 1 on NAS for pain, TMJ noise, and opening limitation belonged to the improved group and those who showed more than 2 on NAS belonged to the unimproved group. The two groups were compared with respect to symptom severity, number of diagnosis, history of trauma, previous treatment, previous medication, and disability of daily activity. A prognostic equation with the factors revealed to be significantly related to the prognosis of conservative treatment was obtained. The obtained results were as follows ; 1. In improved group, mean duration of history was 12 months, mean treatment duration of a patient was 4 months an mean number of treatment was about 10 times. In other words, in unimproved group, mean duration of history was 27.4 months, mean treatment duration of patient was 10.5 months and mean number of treatment was 19 times. 2. In unimproved group, multiple diagnosis, chronicity, disability of daily activity were significantly greater than that of the improved group. 3. Patients in unimproved group revealed severe noise at first visit and smaller maximum comfortable opening comparatively. 4. Prognostic factors such as duration of treatment, number of treatment, multiplicity, and chronicity and disability of daily activity showed a significant relation in prediction of improvement. 5. Prognostic equation with significant variables is as follows ; Y = 1.984 - 0.251Noise + 0.068MCO - 0.673Multiplicity. - 0.958Chronicity - 0.065Disability. Classification accuracy of 70.3 %, sensitivity of 71.4% and specificity of 66.7% were shown. 6. Prognostic equation with all factors is as follows : Y = 1.599 - 0.038Pain - 0.256Noise - 0.006Limitation + 0.068MCO - 0.580Multiplicity - 1.025Chronicity - 0.720Disability - 0.329Medication - 0.087Treatment + 0.740Trauma. Classification accuracy of 70.3 %, sensitivity of 73% and specificity of 64.3% were shown. 7. Prognostic value of the improved group with significant factors was $1.0446{\pm}1.0726$ and prognostic value of the unimproved group with significant factors was $-0.013{\pm}1.0146$. Prognostic value of the improved group with all factors was $1.0465{\pm}1.0849$ and prognostic value of the unimproved group with all factors was $-0.057{\pm}1.0611$.

• 한국수학사학회지
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• 제19권4호
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• pp.133-150
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• 2006

본고에서는 수학사의 교수학적 의미를 살펴보고, 초등학교 6학년 학생에게 적합한 수학사 특강 자료 3차시(120분) 분량을 개발하여, 이를 수학자가 직접 학생들에게 강의함으로써 수학사 내용 및 수학자로 인해 학생들의 수학에 대한 태도에 어떤 변화가 일어나는지를 조사해 보았다. 그 결과 수학사 내용뿐만 아니라 수학자와의 만남도 학생들의 수학에 대한 태도 형성에 긍정적 효과를 주는 것으로 나타났다.

• 정보과학회 컴퓨팅의 실제 논문지
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• 제22권5호
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• pp.235-239
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• 2016

커밋-버그 링크는 커밋히스토리(commit history)와 버그 리포트(bug report) 간의 연결(Link)을 뜻한다. 커밋-버그 링크는 소프트웨어 유지보수와 결함 예측, 버그 추적 시스템(Bug Tracking System)에 이용이 되며, 특히 결함 예측 측면에서는 성능면에서의 기반이 된다. 일반적으로 링크를 자동으로 연결하는 방식은 텍스트 유사도(text similarity)나 시간 간격(time interval), 키워드(keyword) 등을 통해서 추출하였다. 하지만 기존 방식은 커밋히스토리(commit history)의 질적인 부분에 의존적이기 때문에 다수의 링크를 놓치게 된다는 단점이 존재한다. 본 논문에서는 커밋히스토리의 메시지(message)부분에만 의존하지 않고, 버그리포트에서 연결된 커밋히스토리의 파일간의 유사도를 이용하여 링크를 연결할 수 있는 방식을 제안하고 실험을 통하여 본 기법의 적용성을 보인다.

• 산경연구논집
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• 제9권7호
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• pp.7-18
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• 2018

Purpose - The purpose of this paper is to examine how clothing retail buyers (i.e., retail buyers, merchandisers, and storeowners), who are involved in assortment planning and retail buying use assortment criteria in their decisions. Comparisons are made between criteria used by men's wear and women's wear retail buyers as well as criteria used by male and female retail buyers. Research design, data, and methodology - A structured questionnaire was developed to collect data both in English and Korean. After conducting two pilot tests, the survey was conducted in Seoul, South Korea. Mantrala et al.'s 17 inputs of product assortment planning model with 23 assortment criteria from other previous studies were used. Results - Significant differences existed in consideration of assortment criteria between men's wear and women's wear retail buyers as well as between male and female retail buyers. Men's wear retail buyers rated the importance of sales history criteria (i.e., sales history, previous year's sales of same/similar styles) significantly lower than women's wear buyers did. Female retail buyers rated sales history criteria and weather criteria (i.e., unpredicted weather change, forecasting information of weather) significantly higher than male retail buyers did. Conclusions - This study provides guidelines for retail buyers regarding what criteria to use in what situations and how to organize assortment criteria from the most important criterion to the least one. In addition, the findings help them understand other retail buyers' buying behavior.

• 대한수의학회지
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• 제40권3호
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• pp.451-461
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• 2000

The locus coeruleus(LG) is known to be observed a sexual dimorphism in rat CNS. LC is the largest collections of norepinephrine(NE)-containing neurons in the mammalian brain. Especially in rat, all LC neurons contained NE unlike other mammalians, so that specific reactions were found in the tyrosine-hydroxylase(TH) immunoreactive neurons. Sexual dimorphism of rat LC has affected by genes before sex hormone appeared, thereafter affected by sex hormones. In these day, many scientists founded morphological differences between male and female LC morphology, but differences of entire structure was not founded. Thus we investigated sex differences of the LC neuron's morphology in rat by three-dimensional(3-D) reconstruction using Confocal laser scanning microscopy(CLSM). We reported that neuron's shape was relatively-large multipolar neurons and neuron's processes in dorsal LC proceeded to ventral direction in the male and female rat. Male had a longer anterior-posterior length than female had in dorsal LC. In addition to middle-LC, male rat's LC had a more thicker posterior region but had not viewed in a previous study. In reverse, female rat's LC had a thicker anterior region like a previous study. This results using 3-D reconstruction by CLSM showed that the male's LC was more wide-ranging than female's relatively.