• 한국산학기술학회논문지
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• 제22권4호
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• pp.246-254
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• 2021

본 연구는 간호대학생들의 신종 코로나바이러스감염증-19의 지식 및 위험지각과 예방적 건강행위의 관련성을 파악하기 위한 서술적 조사연구이다. A시 S대학교에 재학 중인 간호대학생 291명을 대상으로 구조화된 설문지로 2020년 8월 1일에서 8월 20일까지 설문조사하였고, SPSS WIN 18.0을 이용하여 Independent t-test, One-way ANOVA, Pearson correlation coefficients, Stepwise multiple regression으로 분석하였다. 연구결과, 대상자 나이, 주관적 성적수준에 따라 지식 차이가 나타났고, 학년에 따라 위험지각 차이가 나타났으며, 나이, 주관적 건강수준에 따라 예방적 건강행위 차이가 나타났다. 예방적 건강행위는 지식, 위험지각과 순상관관계를 보였다. 회귀분석 결과, 예방적 건강행위에 미치는 요인은 나이(β=.188, p<.01), 주관적 건강수준(β=-.245, p<.001), 지식(β=.254, p<.001), 위험지각(β=.191, p<.001), 총 설명력은 18.9%(F=17.904, p<.001)로 나타났다. 본 연구를 통해 간호대학생의 신종 코로나바이러스감염증-19의 예방적 건강행위를 증진시키기 위한 교육 프로그램에서는 나이, 주관적 건강수준, 지식, 위험지각에 대한 고려가 필요할 것으로 사료된다. 추후 간호대학생의 코로나바이러스감염증-19의 예방적 건강행위에 대한 이론적 모형을 검증하고 영향요인을 확인하는 연구가 필요하다.

• 한국수정란이식학회지
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• 제22권2호
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• pp.81-87
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• 2007

본 연구에서는 수컷 랫드에 DEHP를 투여하여 실험적으로 생식 독성을 유발하고, vitamin E와 catechin을 단독 및 병용 투여하여 수컷 랫드에서 정소의 조직학적 변화, 정액 특성의 변화 및 정자의 운동성 변화 등을 조사하여 그 예방 효과를 알아보고자 하였다. DEHP를 투여한 군은 대조군에 비해 정자농도, 정자 생존율, 정상 정자율이 감소하였다. DEHP에 의한 생식 독성을 예방하기 위해 vitamin E와 catechin을 단독 또는 병행 투여한 결과, DEHP를 투여한 군에 비하여 정자 농도, 정자 생존율, 정상 정자율이 증가하였다. 이러한 결과를 종합해 볼 때, catechin과 vitamin E의 투여는 DEHP에 의한 생식 독성을 예방하는 효과가 있는 것으로 사료된다.

• 한국치위생학회지
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• 제12권2호
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• pp.335-343
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• 2012

Objectives : The aim of this investigation was to evaluate the remineralization effect of Bamboo salt and NaF+Bamboo salt solutions on bovine enamel formed incipient artificial enamel caries by microcomputed tomography (micro CT). Methods : Experimental solutions were distilled water(negative control), 2% sodium fluoride solution (2% NaF group), 3% bamboo salt solution (3% BS group) and the solution mixed 2% sodium fluoride solution and 3% bamboo salt solution (2% NaF+3% BS group). Specimens were prepared from extracted bovine teeth and divided into 4 groups of 10 specimens each by randomized blocks according to density. Then the specimens surface were divided equally into three parts to observe sound enamel area, incipient enamel carious area and remineralized enamel area. Only one-third of specimen surface was coated with nail varnish and these were exposed to a lactate carbopol buffer system for 72 hours. Then one-half of the demineralized enamel area was coated with nail varnish. The specimens were carried out under pH cycling model for 14 days as follows; samples were immersed in each experimental solution for 2 mins 3 times per day, demineralized for 4 hours and in mixed saliva for the remaining hours. After pH cycling, density was measured using micro CT. Results : All experimental groups showed remineralization effects except for negative control group(p<0.05). The differences of density after experimental solution treatment were statistically significant difference among 4 groups (p<0.01). The density difference values of groups were $0.04{\pm}0.01$ in negative control group, $0.19{\pm}0.01$ in 2% NaF group, $0.14{\pm}0.01$ in 3% BS group, and $0.21{\pm}0.01$ in 2% NaF+3% BS group. Conclusions : The bamboo salt solution showed remineralization effects on incipient artificial enamel caries and the solution mixed sodium fluoride solution and bamboo salt solution showed more remineralization effects than the bamboo salt solution. Thus, it is suggested that bamboo salt can be used as remineralization agent in incipient enamel caries lesion.

• Journal of Preventive Medicine and Public Health
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• 제24권3호
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• pp.279-286
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• 1991

Much of the working population in developing countries are engaged in shift work now and the number of shift workers is not expected to decrease in the future mostly because the need for continuity of production is increasing. Therefore, the possible effects of shift work on health are of particular interest, and in fact, there have been many epidemiological studies on shift work since the first world war. However, no studies on health effects of shift work have been reported in Korea, and the existing studies in western world have arrived at quite different conclusions mainly because the conditions of work other than shift work, such as age and selection of workers, work environment, and labor conditions also influence the health of workers. This study was firstly carried out in Korea to investigate the health risks related to shift work with 2,093 female workers randomly selected from three major manufacturing industries in proportion to total number of female workers in those industries. Differences of work conditions other than shift work in this study were adjusted by multivariate analysis. Ma findings obtained from this study are as follows : 1. There were significant differences between shift and day workers in the distribution of age, type of industry, condition of noise and dust, regularity of mealtime, working position, and working duration. Shift workers tended to be younger, to have shorter working duration, to have more irregular mealtime, to work in standing position, and to work under more noisy and dusty environment than day workers. 2. Univariate analysis showed that shift work increased the Todai Health Index (THI) scores of digestive tract, respiratory tract, and mental instability symptom categories. Shift work also increased days of sickness absence and number of industrial accident per 100 workers per month. 3. Multivariate analysis that adjusted the differences of demographic, occupational and non-occupational health-related working conditions showed that digestive tract symptom and mental instability symptom scores were significantly higher in shift workers than those in day workers. Based on these study results, it is concluded that the shift work has significant effects on some psychophysiological conditions of the workers and the effects are also influenced by several other personal and working conditions.

• Journal of Preventive Medicine and Public Health
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• 제34권2호
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• pp.109-118
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• 2001

우리는 이 글에서 대기오염의 건강영향, 특히 사망에 대한 역학 연구 결과를 해석하는데 논란이 되고 있는 쟁점들을 고찰하였다. 과거 런던스모그 때와 같은 극심한 대기오염 사건 때는 그로 인한 건강영향도 매우 자명하여 별다른 논란의 소지가 없었다. 그러나 오늘날 우리가 경험하는 수준의 대기오염은 눈에 바로 띨 정도의 건강영향을 초래하지는 않기 때문에 많은 연구에서 관찰되는 통계적 유의성이 인과적 관련성을 의미하는지에 대한 많은 논란이 있다. Hill의 인과성기준에 비추어 대기오염에 관한 역학 연구 결과들을 평가해보면 각 기준 별로 부합되는 소견과 그렇지 않은 소견이 같이 존재하지만 전체적으로는 인과적인 관련성을 지지하는 증거들이 많은 편이다. 특히 세계 여러 지역에서 수행된 연구들에서 공통된 결과들이 나오는 것이 인과성을 지지해주는 강력한 근거라고 할 수 있다. 대기오염이 사망을 증가시킨다고 가정할때 구체적으로 어떤 병태 생리적인 기전을 통해서 증가시키는지는 아직 충분히 밝혀져 있지 않다. 현재까지의 역학연구 결과들과 동물실험 결과들을 종합해보면 대기오염 물질이 일차적으로 폐포에 염증을 유발하고 이에 따라 이차적으로 혈장의 응고성이 증가하거나, 심장에 대한 자율신경조절에 이상이 생겨서 사망위험이 증가한다는 가설이 가장 폭넓은 지지를 받고 있다. 시계열분석에서 나타나는 대기오염에 의한 초과사망자들이 어떤 특성을 가지고 있는지에 대한 논란도 많다. 대기오염이 아니더라도 곧 사망할 사람들이 대기오염 때문에 몇 일 앞당겨 사망한다는, 즉 추수효과에 의한 것이라는 것이 상식적인 판단이지만 최근의 연구들은 추수효과 외에도 대기오염에 의해 실질적인 수명의 감소가 있다는 증거들을 제시하고 있다. 대기오염 물질과 사망의 양-반응 관계가 어떤 모양일지, 그리고 문턱값이 존재하는지의 여부도 중요한 관심사이다. 특히 문턱값의 존재 여부는 대기오염 관리 대책과도 밀접한 관계가 있다. 대기환경 기준을 정해서 대기오염 수준을 관리하는 현재의 대책은 문턱간의 존재를 전제하고 있기 때문이다. 그러나 현재까지의 증거를 종합해보면 대기오염과 사망의 관련성은 문턱값이 없는 선형적 관계일 가능성이 높다. 따라서 향후 대기오염 관리대책에서는 대기오염 물질의 평균농도를 낮추려는 노력을 병행하여야 할 것을 생각한다.

• 대한치과의사협회지
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• 제57권10호
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• pp.560-568
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• 2019

Purpose: This study evaluated the antibacterial effects of curcuma, ginger, and finger root extracts in water-soluble powder on planktonic Streptococcus mutans(S.mutans), which is known to cause dental caries, in order to confirm whether these extracts could perform as photosensitizers for the effects of photodynamic therapy (PDT). Methods: This study used the strain of streptococcus mutans ATCC 25175 distributed by the Korean Collection for Type Cultures of the Korea Research Institute of Bioscience & Biotechnology. Commercial edible curcuma, ginger and finger root were used as the natural extracts for the use of photosensitizer. To extract organic solvent, 3 g of each powder was mixed in $30m{\ell}$ of dimethyl sulfoxide (DMSO, VWR, Germany) before extraction. $1.8m{\ell}$ of the photosensitizer solution, manufactured in the concentrations of 5, 0.5, and $0.05mg/m{\ell}$, was mixed with $0.2m{\ell}$ of the S. mutans culture medium that had been cultured for 2 days. To induce the photodynamic reaction, Qraycam (AIOBIO, Seoul, Korea) equipped with 405 nm LED was used to expose light for 5 minutes to irradiate 59 nW energy for 300 seconds. Results: Compared with the case with no light, a higher photodynamic therapeutic effect was confirmed with $0.05mg/m{\ell}$ curcuma powder extract, the concentration of $0.5mg/m{\ell}$ and LED light of 405 nm wavelength (p=0.000, p=0.003). $0.05mg/m{\ell}$ of curcuma powder extract and the concentration of $0.5mg/m{\ell}$ showed 100% antibacterial effect when exposed to light, whereas the concentration of $5mg/m{\ell}$ showed 11.95% antibacterial effect. When exposed to light, $0.05mg/m{\ell}$ of ginger powder extract showed an antibacterial effect which didn't statistically decrease. The concentrations of $0.5mg/m{\ell}$ and $5mg/m{\ell}$ did not show any antibacterial effects. As a result of examining any photodynamic therapeutic effects of finger root powder extract on S. mutans, no statistically significant effect was found. Conclusion: The curcuma powder extract is expected to perform as a photosensitizer. Even though belonging to the same ginger family, ginger powder and finger root powder seem difficult to perform as photosensitizer.

• 지역사회간호학회지
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• 제26권4호
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• pp.398-404
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• 2015

Purpose: This study was conducted to examine the effects of osteoporosis prevention education on Korean breast cancer patients' knowledge and health promoting behavior. Methods: The participants in this study included breast cancer patients who were registered at a self-help group organized by the Breast Cancer Center of a university hospital in Seoul, Korea. The intervention group received 60 minutes' didactic instruction followed by 30 minutes' interactive session, and reinforcement education with leaflets was given three weeks after the group intervention. In order to measure the effects of the intervention, this study used valid and reliable scales on the knowledge of osteoporosis and health promoting behavior for preventing osteoporosis. A post-test was conducted 12 weeks after the intervention. Results: The results showed significant improvement in three of the five factors of osteoporosis knowledge including bone physiology, the characteristics of osteoporosis, and preventive behaviors in the intervention group. Overall health promoting behavior for preventing osteoporosis had significantly increased in the intervention group compared to the control group. Conclusion: Osteoporosis preventive education improved breast cancer patients' knowledge of osteoporosis and health promoting behavior for preventing osteoporosis by inducing their voluntary participation in self-care activities.

• 대한예방한의학회지
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• 제18권2호
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• pp.101-113
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• 2014

Objective : Ephedra Herba has been widely used for patients with common cold, asthma in eastern countries, especially china japan and korea. Recently it has been also used for obesity in clinic with high frequency. This study was designed to investigate the effects of Ephedra Herba ethyl-acetate fraction (EEAF) on hyperlipidemic mice. Method : Effects on total cholesterol, HDL-cholesterol, triglyceride, AST, ALT, fasting blood glucose in serum were measured in this experiment, and in addition, histopathological and gene expression changes in liver tissue was also observed. Results : In our study, EEAF did not affect weight gain in hyperlipidemic mice. Oral administration of EEAF lowered levels of total cholesterol which were elevated by induction of hyperlipidemia. And administration of EEAF lowered fasting blood glucose significantly. By carrying out ontological analysis, large numbers of genes were identified in up or down regulated genes. The expression of the genes that were altered in response to high-fat diet was restored to normal levels in EEAF treated mice, with a recovery rate of 49%. And it was considered that fatty acid metabolism was one of important key pathway of the recovery. Conclusion : Results in our study suggest that EEAF can prevent obese and through regulation of dyslipidemia and hyperglycaemia.

• Journal of Preventive Medicine and Public Health
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• 제44권5호
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• pp.191-200
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• 2011

Objectives: The goal of this paper is to examine the social network effects on post-traumatic sdress disorder (PTSD) in female North Korean immigrants who entered South Korea in 2007. Specifically, it attempts to verify if the density and composition of networks make a difference after controlling for the network size. Methods: A multivariate logistic regression is used to probe the effects of social networks using the North Korean Immigrant Panel data set. Because the data set had only completed its initial survey when this paper was written, the analysis was cross-sectional. Results: The size of the support networks was systematically related to PTSD. Female North Korean immigrants with more supporting ties were less likely to develop PTSD, even after controlling for other risk factors (odds-ratio for one more tie was 0.8). However, once we control for the size of the network, neither the density nor the composition of the networks remains statistically significant. Conclusions: The prevalence of the PTSD among female North Korean immigrants is alarmingly high, and regardless of the characteristics of supporting network members, the size of the supporting networks provides substantial protection. This implies that a simple strategy that focuses on increasing the number of supporting ties will be effective among North Korean immigrants who entered South Korea in recent years.

• 대한예방한의학회지
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• 제19권2호
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• pp.145-157
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• 2015

Objective : This study aimed to analyze a comprehensive feature of experimental research on Insamyangyoungtang and develop a strategy that can be used for experimental studies on Insamyangyoung-tang in the future. Method : The journal search was performed using six databases : PubMed, Chinese database (China Network Knowledge Infrastructure, [CNKI]), Japan database (Japan Science and Technology Information Aggregator, Electronic, [J-STAGE]) and three Korean databases (Oriental Medicine Advanced Searching Integrated System [OASIS], Research Information Service System [RISS], and Korean Studies Information Service System [KISS]). We used limited keywords and analyzed studies by publication year, experimental models, and the subjects of biological activities. The mechanism of pharmacological activity in accordance with the therapeutic effects of Insamyangyoung-tang was noted. Results and Conclusion : A total of 43 studies (6 domestic studies and 37 foreign ones) were examined according to the inclusion criteria of the experimental study. Research on the pharmacological activities of Insamyangyoung-tang showed its therapeutic effects on the nervous and immune systems, as well as its anti-aging, anti-fatigue, and hematopoietic effects. Additional efficacy and safety assessments and experimental and clinical studies should be performed to evaluate the mechanism of Insamyangyoung-tang. The present review has provided preliminary information for further studies on Insamyangyoung-tang.