• Journal of the Korean Institute of Gas
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• v.20 no.6
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• pp.43-49
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• 2016

In this paper, purpose of study is emissions characteristics according to effects of heating value variations of CNG fuel in a dual-fuel engine fueled by diesel and natural gas. For heating value variation of CNG fuel, nitrogen gas was mixed with pure CNG fuel. So the higher heating value was changed from $10,400kcal/Nm^3$ to $9,400kcal/Nm^3$. Under one condition of CNG substitution rate was fixed at 80%, diesel fuel was injected at a fixed injection timing of 16 CAD BTDC and fuel pressure was also fixed at 110 MPa. The condition of tested engine was 1800 rpm and 500Nm. Emissions were sampled in exhaust pipe was located at downstream turbocharger. As a result, emissions characteristics were checked in heating value variations of CNG fuel with mixed nitrogen gas THC, $CH_4$ and CO emissions decreased and NOx and $CO_2$ increased.

• Journal of Pharmacopuncture
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• v.18 no.1
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• pp.63-71
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• 2015

Objectives: This study was carried out to analyze the single-dose toxicity of Eun-Bi San pharmacopuncture injected into the muscle of Sprague-Dawley (SD) rats. Methods: All experiments were performed at Biotoxtech, an institution certified to conduct non-clinical studies under the Good Laboratory Practice (GLP) regulations. Six week old SD rats reared by ORIENTBIO were chosen for this pilot study. The reason SD rats were chosen is that they have been widely used in safety tests in the field of medicine, so the results can be easily compared with many other databases. The Eun-Bi San pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (KPI, K-GMP). The constituents of the Eun-Bi San pharmacopuncture are Angelicae gigantis radix, Strychni semen and Glycyrrhizae radix. These were extracted at low temperature and low pressure in an aseptic room at the KPI. Doses of Eun-Bi San pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. This study was performed under the approval of the Institutional Animal Ethics Committee of Biotoxtech Co., Ltd. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To determine if abnormalities existed in any organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The results of this study suggest that treatment with Eun-Bi San pharmacopuncture is relatively safe and that its clinical use may be beneficial. Further evaluations and studies on this subject will be needed to provide more concrete evidence in support of these conclusions.

• The Korean Journal of Pain
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• v.7 no.1
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• pp.100-105
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• 1994

This is a study of decrease in both stump pain and unidentified complaints after removal of neuroma on an amputated left thigh. The patient was a 44 year old woman who received an operation after a motorcycle accident 20th of March, 1991. She started a rehabilitation program in early June of the same year. How ever the patient complained of a squeezing pain on the amputated area. This symptom became more severe after the removal of the nails in September. The pain was perceived as a mental problem and the patient was released from the previous hospital. The pain continued and on the 9th of March, 1992, the patient was introduced to our pain clinic. The patient complained about the cold sensation and pressure pain of the amputated area at the beginning. Later she also expressed various unidentified complaints. No improvement resulted after conducting an epidural block and a lumbar sympathetic ganglion block. MMPI test showed psychological instability. Local injection showed some positive effects, which led to considerations concerning the possibility of neuroma. After confirming the existence of neuroma through CT and MRI, neuromectomy was performed. After the removal of neuroma, the unidentified complaints as well as the stump pain decreased.

• The Korean Journal of Pain
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• v.20 no.2
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• pp.169-173
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• 2007

Background: Although the use of intravenous patient controlled analgesia (IVPCA) has been compared to the use of patient conrolled epidural analgesia (PCEA), there is no optimal administration route of alfentanil for the treatment of postoperative pain. This randomized double-blind study compared the efficacy of the use of IVPCA and PCEA for postoperative pain and the side effects after a total abdominal hysterectomy (TAH). Methods: Sixty patients undergoing a TAH were randomly assigned to receive either IVPCA (Group I) or PCEA (Group E) for the infusion of alfentanil for postoperative pain control. In both groups, a loading dose of $750{\mu}g$ alfentanil was administered. All patients received the same continuous infusion rate (0.3 mg/h), bolus dose (0.15 mg), and lockout time (15 min). The incidence of side effects, the VAS (visual analog scale) of pain, blood pressure, and heart rate were checked for 20 hours after the loading dose injection. Results: The VAS of pain was not significantly different between the two groups of patients. The onset of the analgesic effect was significantly more rapid in the Group I patients than in the Group E patients. There was no difference in side effects for either group. Conclusions: When considering multiple factors such as the onset of analgesia, technical difficulties or infection after the procedure, IVPCA using alfentanil is more useful than PCEA for postoperative pain control after a TAH.

• Journal of the Korean Institute of Gas
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• v.20 no.1
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• pp.13-22
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• 2016

This paper presents development of an appropriate procedure and flow chart to analyze shale gas production data obtained from a multi-fractured horizontal well according to flow characteristics in order to calculate an estimated ultimate recovery. Also, the technical considerations were proposed when a rate transient analysis was performed with field production data occurred to only $1^{st}$ transient flow. If production data show the $1^{st}$ transient flow from log-log and square root time plot analysis, production forecasting must be performed by applying different method as before and after of the end of $1^{st}$ linear flow. It is estimated by an area of stimulated reservoir volume which can be calculated from analysis results of micro-seismic data. If there are no bottomhole pressure data or micro-seismic data, an empirical decline curve method can be used to forecast production performance. If production period is relatively short, an accuracy of production data analysis could be improved by analyzing except the early production data, if it is necessary, after evaluating appropriation with near well data. Also, because over- or under-estimation for stimulated reservoir volume could take place according to analysis method or analyzer's own mind, it is necessary to recalculate it with fracture modeling, reservoir simulation and rate transient analysis, if it is necessary, after adequacy evaluation for fracture stage, injection volume of fracture fluid and productivity of producers.

• Nuclear Engineering and Technology
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• v.27 no.4
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• pp.470-482
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• 1995

The Ulchin 3&4, which are 2825 MWt PWRs, adopted Safety Depressurization System (SDS) to mitigate the beyond design basis event of Total Less of Feedwater(TLOFW). In this study the results and methodology of the analyses for the determination of SDS bleed capacity are discussed. The SDS design bleed capacity has been determined from the CEFLASH-4AS/REM simulation according to the following design criteria : 1) Each SDS flow path, in conjunction with one of two High Pressure Safety Injection (HPSI) pumps, is designed to have a sufficient capacity to prevent core uncovery if one SDS path is opened simultaneously with the opening of the Pressurizer Safety Valves (PSVs). 2) Both SDS bleed paths are designed to have sufficient total capacity with both HPSI pumps operating to prevent core uncovery if the Feed and Bleed (F&B) initiation is delayed up to thirty minutes from the time of the PSVs lift. To verify the results of CEFLASH-4AS/REM simulation a comparative analysis kas also been per-formed by more sophisticated computer code, RELAP5/MOD3. The TLOFW event without operator recovery and TLOFW event with F&B are analyzed. The predictions by the CEFLASH-4AS/REM of the transient too phase system behavior are in good qualitative and quantitative agreement with those by the RELAP5/MOD3 simulation. Both of the results of analyses by CEFLASH-4AS/REM and RELAP5/MOD3 have demonstrated that decay heat removal and core inventory make-up can be successfully accomplished by F&B operation during now event for the Ulchin 3&4.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.1 no.2
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• pp.123-129
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• 2015

$^{64}Cu$-labeled diacetyl-bis($N^4$-methylthiosemicarbazone) is a promising agent for internal radiation therapy and imaging of hypoxic tissues. In the study, we confirmed hypoxia regions in VX2 tumor implanted rabbits with injection $^{64}Cu$-ATSM and $^{18}F$-FDG using positron emission tomography (PET)/computed tomography (CT). PET images with $^{18}F$-FDG and $^{64}Cu$-ATSM were obtained for 40 min by dynamic scan and additional delayed PET images of $^{64}Cu$-ATSM the acquired up to 48 hours. Correlation between intratumoral $O_2$ level and $^{64}Cu$-ATSM PET image was analyzed. $^{64}Cu$-ATSM and $^{18}F$-FDG were intravenously co-injected and the tumor was dissected and cut into slices for a dual-tracer autoradiographic analysis. In the PET imaging, $^{64}Cu$-ATSM in VX2 tumors displayed a specific uptake in hypoxic region for48 h. The uptake pattern of $^{64}Cu$-ATSM in VX2 tumor at 24 and 48 h did not match to the $^{18}F$-FDG. Through ROI analysis, in the early phase (dynamic scan), $^{18}F$-FDG has positive correlation with $^{64}Cu$-ATSM but late phase (24 and 48 h) of the $^{64}Cu$-ATSM showed negative correlation with $^{18}F$-FDG. High uptake of $^{64}Cu$-ATSM in hypoxic region was responded with significant decrease of oxygen pressure, which confirmed by $^{64}Cu$-ATSM PET imaging and autoradiographic analysis. In conclusion, $^{64}Cu$-ATSM can utilize for specific targeting of hypoxic region in tumor, and discrimination between necrotic- and viable hypoxic tissue.

• Restorative Dentistry and Endodontics
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• v.30 no.6
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• pp.470-476
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• 2005

The purpose of this Study was to invest)gate the function or calcitonin gene-related peptide (CGRP) in regulatory mechanism of pulpal microcirculation with the aim of elucidating neurogenic inflammation. Experiments were performed on twelve cats under general anesthesia. CGRP was administered through the femoral vein to see the systemic Influence and through the external carotid artery to see the local effect. Sympathetic nerve to the dental pulp was stimulated electrically and pulpal blood flow (PBF) was measured with a laser Doppler flowmeter on the canine teeth to the drug administration. The paired variables of control and experimental data were compared by paired t-test and differences with p < 0.05 were considered statistically significant. Systemic administration of CGRP $(0.3{\mu}g/ka)$ exerted decreases in systemic blood pressure and caused changes in PBF with an initial increase i311owed by decrease and a move marked second increase and decrease. Close intra-arterial (i.a.) injection of CCRP $(0.03{\mu}g/kg)$ resulted in slight PBF increase. The effect of CGRP resulted in no significant increase in PBF in the presence of $CGRP_{8-37}$. The electrical stimulation of the sympathetic nerve alone resulted in PBF decreases. The j.a. administration of CGRP following the electrical stimulation of the sympathetic nerve compensated the decreased PBF. Therefore, CGRP effectively blocked the sympathetic nerve stimulation-induced PBF decrease. Results of the present study have provided evidences that even though the local vasodilatory function of CGRP are weak, CCRP is effectively involved in blocking the vasoconstriction caused by sympathetic nerve stimulation in the feline dental pulp.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.506-512
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• 2018

The fine dust generated in the home and restaurant business occupies a low ratio of about 4% of the total fine dust emissions. However, at the foodservice business, the rate of change of the pollutant concentration is very high, so that the temporary fine dust concentration can be measured up to 60 times. The pollutants generated from non-industrial combustion plants consist of particulate fine dust and gaseous organic compounds. To remove these pollutants, cleaning dust collection system, which is an effective system for simultaneous removal of gaseous and particulate matter, is applied. This is a method of increasing the probability of diffusion capture of the Brownian motion by pressurized liquid injection method using the atomizing nozzle. The dust removal efficiency of the fine dust collecting system was analyzed by nozzle spraying air pressure condition and angle using the manufactured fine dust removing system. As a result, it was confirmed that the efficiency of removal of fine dust and gaseous organic compounds was more than 90%. The developed system is expected to be highly usable in the future because it can remove particulate dust from the existing plant hood system without any installation cost.

• Journal of Korean Society of Water and Wastewater
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• v.34 no.6
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• pp.393-402
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• 2020

In the membrane process, it is important to improve water treatment efficiency to ensure water quality and minimize membrane fouling. In this study, a pilot study of membrane process using reservoir water was conducted for a long time to secure high flux operation technology capable of responding to influent turbidity changes. The raw water and DAF(Dissolved Air Flotation) treated water were used for influent water of membrane to analyze the effect of water quality on the TMP (Trans Membrane Pressure) and to optimize the membrane operation. When the membrane flux were operated at 70 LMH and 80 LMH under stable water quality conditions with an inlet turbidity of 10 NTU or less, the TMP increase rates were 0.28 and 0.24 kPa/d, respectively, with minor difference. When the membrane with high flux of 80 LMH was operated for a long time under inlet turbidity of 10 NTU or more, the TMP increase rate showed the maximum of 43.5 kPa/d. However, when the CEB(Chemically Enhanced Backwash) cycle was changed from 7 to 1 day, it was confirmed that the TMP increase rate was stable to 0.23 kPa/d. As a result of applying pre-treatment process(DAF) on unstability water quality conditions, it was confirmed that the TMP rise rates differed by 0.17 and 0.64 kPa/d according to the optimization of the coagulant injection. When combined with coagulation pretreatment, it was thought that the balance with the membrane process was more important than the emphasis on efficiency of the pretreatment process. It was considered that stable TMP can be maintained by optimizing the cleaning conditions when the stable or unstable water quality even in the high flux operation on membrane process.