In this study, we suggest an empirical forecast of CIR (Corotating Interaction Regions) and geomagnetic storm based on the information of coronal holes (CH). For this we used CH data obtained from He I $10830{\AA}$ maps at National Solar Observatory-Kitt Peak from January 1996 to November 2003 and the CIR and storm data that Choi et al. (2009) identified. Considering the relationship among coronal holes, CIRs, and geomagnetic storms (Choi et al. 2009), we propose the criteria for geoeffective coronal holes; the center of CH is located between $N40^{\circ}$ and $S40^{\circ}$ and between $E40^{\circ}$ and $W20^{\circ}$, and its area in percentage of solar hemispheric area is larger than the following areas: (1) case 1: 0.36%, (2) case 2: 0.66%, (3) case 3: 0.36% for 1996-2000, and 0.66% for 2001-2003. Then we present contingency tables between prediction and observation for three cases and their dependence on solar cycle phase. From the contingency tables, we determined several statistical parameters for forecast evaluation such as PODy (the probability of detection yes), FAR (the false alarm ratio), Bias (the ratio of "yes" predictions to "yes" observations) and CSI (critical success index). Considering the importance of PODy and CSI, we found that the best criterion is case 3; CH-CIR: PODy=0.77, FAR=0.66, Bias=2.28, CSI=0.30. CH-storm: PODy=0.81, FAR=0.84, Bias=5.00, CSI=0.16. It is also found that the parameters after the solar maximum are much better than those before the solar maximum. Our results show that the forecasting of CIR based on coronal hole information is meaningful but the forecast of goemagnetic storm is challenging.
Difractose anhydrides (DFAs) is studied as a sweetener for diabetics because of its structural property. DFAs have four types: DFA I, III, IV (degradation of levan) and V (degradation of inulin). Especially, DFA IV has been shown to enhance the absorption of calcium in experiments using rats. Levan fructotransferase is an enzyme for producing di-d-fructose-2,6':6,2-dianhydride (DFA IV). To identify structural characterization, we purified wild-type and mutants (D63A, D195N and N85S) of levan fructotransferase (LFTase) from Microbacterium sp. AL-210. These proteins were purified to apparent homogeneity by Ni-NTA affinity column, Q-sepharose ion exchange and gel filtration chromatography and detected by SDS-PAGE. They were also analyzed by circular dichroism (CD) measurements, JNET secondary structure prediction, activity measurements at various temperatures, and pH analysis. The optimum pH for the enzyme-catalyzed reaction was pH 7.5 and optimum temperature was observed at $55^{\circ}C$. Along with wild-type LFTase, mutants were analyzed by CD measurement, fluorescence analysis and differential scanning calorimetry (DSC). N85S showed less $\alpha$-helix and more $\beta$ strand than others. Also, N85S showed almost the same curve as wild-type in their steady-state fluorescence spectra, whereas mutant D63A and D195N showed higher intensity than wild-type. The amino acid sequence of wild-type LFTase was compared to the sequences of exo-inulinase from Aspergillus awamori, a plant fructan 1-exohydrolase from Cichorium intybus, and Thermotogo maritime (Tm) invertase and showed a high identity with Exo-inulinase from Aspergillus awamori.
An understanding of soil-structure interaction is the key to rational and economical design for laterally loaded drilled shafts. It is very difficult to formulate the ultimate lateral capacity into a general equation because of the inherent soil nonlincarity, nonhomogeneity, and complexity enhanced by the three dimensional and asymmetric nature of the problem though extensive research works on the behavior of deep foundations subjected to lateral loads have been conducted for several decades. This study reviews the four most well known methods (i.e., Reese, Broms, Hansen, and Davidson) among many design methods according to the specific site conditions, the drilled shaft geometric characteristics (D/B ratios), and the loading conditions. And the hyperbolic lateral capacities (H$_h$) interpreted by the hyperbolic transformation of the load-displacement curves obtained from model tests carried out as a part of this research have been compared with the ultimate lateral capacities (Hu) predicted by the four methods. The H$_u$ / H$_h$ ratios from Reese's and Hansen's methods are 0.966 and 1.015, respectively, which shows both the two methods yield results very close to the test results. Whereas the H$_u$ predicted by Davidson's method is larger than H$_h$ by about $30\%$, the C.0.V. of the predicted lateral capacities by Davidson is the smallest among the four. Broms' method, the simplest among the few methods, gives H$_u$ / H$_h$ : 0.896, which estimates the ultimate lateral capacity smaller than the others because some other resisting sources against lateral loading are neglected in this method. But it results in one of the most reliable methods with the smallest S.D. in predicting the ultimate lateral capacity. Conclusively, none of the four can be superior to the others in a sense of the accuracy of predicting the ultimate lateral capacity. Also, regardless of how sophisticated or complicated the calculating procedures are, the reliability in the lateral capacity predictions seems to be a different issue.
This study was performed to identify the characteristics of the OFC1 gene (locus: chromosome 6p24.3) in Korean patients, which is assumed to be the major gene behind the nonsyndromic cleft lip and palate. The sample consisted of 80 subjects: 40 nonsyndromic cleft lip and palate patients (proband, 20 males and females, mean age 14.2 years); and 40 normal adults (20 males and 20 females, mean age 25.6 years). Using PCR-based assay, the OFC1 gene was amplified, sequenced, and then searched for similar protein structures. Results were as follows: 1. The OFC1 gene contains the microsatellite marker 'CA' repeats. The number of the reference 'CA' repeats was 21 times, and formed as TA(CA)11TA(CA)10. But, in Koreans, the number of tandem 'CA' repeats was varied from 17 to 26 except 18, and 'CA' repeats consisted of TA(CA)n. 2. Nine allelic variants were found. Distribution of the OFC1 allele was similar between the patients and control group. 3. There was a replacement of the base 'T' to 'C' after 11 tandem 'CA' repeats in Koreans compared with Weissenbach's report. However, the difference did not seem to be the ORF prediction results between Koreans and Weissenbach's report. 4. The BLAST search results showed the Telomerase reverse transcriptase (TERT) and the Nucleotide binding protein 2 (NBP2) as similar proteins. The TERT was a protein product by the hTERT gene in the locus 5p15.33 (NCBI Genome Annotation; NT023089) The NBP2 was a protein product by the ABCC3 (ATP-binding cassette, sub-family C) gene in the locus 17q22 (NCBI Genome Annotation; NT010783). 5. In the Pedant-Pro database analysis, the predictable protein structure of the OFC1 gene had at least one transmembrane region and one non-globular region.
Kim, Yeong Sik;Park, Shang Ho;An, Ik Tae;Choo, Yeon Moon
Journal of Wetlands Research
/
v.22
no.3
/
pp.194-199
/
2020
Unlike in the past, the world is facing water shortages due to climate change and difficulties in simultaneously managing the risks of flooding. The Four Major Rivers project was carried out with the aim of realizing a powerful nation of water by managing water resources and fostering the water industry, and the construction period was relatively short compared to the unprecedented scale. Therefore, the prediction and analysis of how the river environment changes after the Four Major Rivers Project is insufficient. Currently, part of the construction section of the Four Major Rivers Project is caused by repeated erosion and sedimentation due to the effects of sandification caused by large dredging and flood-time reservoirs, and the head erosion of the tributaries occurs. In order to solve these problems, the riverbed maintenance work was installed, but it resulted in erosion of both sides of the river and the development of new approaches and techniques to keep the river bed stable, such as erosion and excessive sedimentation, is required. The water agent plays a role of securing a certain depth of water for the main stream by concentrating the flow so much in the center and preventing levee erosion by controlling the flow direction and flow velocity. In addition, Groyne products provide various ecological environments by forming a natural form of riverbeds by inducing local erosion and deposition in addition to the protection functions of the river bank and embankment. Therefore, after reviewing the method of determining the shape of the Groyne structure currently in use by utilizing the mobile limit flow rate and marginal reflux force, a new Critical Movement Velocity(${\bar{U}}_d$) and a new resistance coefficient formula considering the mathematical factors applicable to the actual domestic stream were developed and the measures applicable to Groyne installation were proposed.
One of the most important issues in guaranteeing the high degree of QoS on mobile computing is how to reduce hand-off drops caused by lack of available bandwidth in a new cell. Each cell can request bandwidth reservation to its adjacent cells for hand-off calls. This reserved bandwidth can be used only for hand-offs, not for new calls. It is also important to determine how much of bandwidth should be reserved for hand-off calls because reserving too much would increase the probability of a new call being blocked. Therefore, it is essential to develop a new mechanism to provide QoS guarantee on a mobile computing environment by reserving an appropriate amount of bandwidth and call admission control. In this paper. bandwidth reservation and call admission control mechanisms are proposed to guarantee a consistent QoS for multimedia traffics on a mobile computing environment. For an appropriate bandwidth reservation, we propose an adaptive bandwidth reservation mechanism based on an MPP and a 2-tier cell structure. The former is used to predict a next move of the client while the latter to apply our mechanism only to the client with a high hand-off probability. We also propose a call admission control that performs call admission test only on PNC(Predicted Next Cell) of a client and its current cell. In order to minimize a waste of bandwidth caused by an erroneous prediction of client's location, we utilize a common pool and QoS adaptation scheme. In order evaluate the performance of our call admission control mechanism, we measure the metrics such as the blocking probability of new calls, dropping probability of hand-off calls, and bandwidth utilization. The simulation results show that the performance of our mechanism is superior to that of the existing mechanisms such as NR-CAT2, FR-CAT2, and AR-CAT2.
Kim, Jeong Ho;Yoon, Ji Hun;Lee, Sang Hoon;Choi, Won Jun;Yoon, Yong Han
Korean Journal of Environment and Ecology
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v.32
no.4
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pp.413-424
/
2018
The study analyzed the effects of topographic structures and altitude in mountainous parks in Mt. Namsan in Gyeongju on the generation of anions. The temperature was at ridge ($9.82^{\circ}C$) > valley ($8.44^{\circ}C$), the relative humidity valley (59.01 %) > ridge (58.64 %), the solar radiation ridge ($34.40W/m^2$) > valley($14.69W/m^2$), the wind speed ridge (0.63m/s) > valley(0.37m/s), and the negative ion valley($636.81ea/cm^3$) > ridge($580.04ea/cm^3$). In the valley, the correlation with altitude was verified for the temperature, relative humidity, solar radiation, and negative ion generation in the valley. The relative humidity, solar radiation, and negative ion indicated a positive correlation while the temperature had a negative correlation. In the ridge, the correlation with altitude was verified for the temperature, relative humidity, wind speed, solar radiation, and negative ion generation. The relative humidity, solar radiation, and negative ion generation indicated a positive correlation while the temperature and wind speed had a negative correlation. The regression analysis showed the prediction equation of y=-0.006x+9.663 (x=altitude, y=temperature) in the valley and y=-0.009x+11.595 (x=altitude, y=temperature) in the ridge for the temperature, y=0.027x+53.561 (x=altitude, y=relative humidity) in the valley and y=0.008x+56.646 (x=altitude, y=relative humidity) in the ridges for the relative humidity, and y=0.027x+53.561 (x=altitude, y=negative Ion generation) in the valley and y= 0.008x+56.646 (x=altitude, y=negative Ion generation) in the ridge for the negative ion generation.
This study, targeting Namhan Mountain Fortress which was designated as a No. 57 national historic site and placed on the World Heritage Tentative List in 2010, was intended to identify the change of vegetation structures by reviewing past references, pictures, research data and additionally conducting a site survey. Also, it was designed to draw up measures for restoring vegetation suitable for historically and culturally valuable Namhan Mountain Fortress. According to the biotope mapping of study site, Quercus spp. forest distributed a greatest part of area with 40.8% of $2,611,823m^2$. Pinus densiflora forest, highly likely to go through ecological succession, was dispersed in the whole region of Cheongryangsan, the area from West Gate to North Gate and the ranges between South Gate to Cheongryangsan with taking 16.5%. Pinus densiflora forest with a low probability of succession amounted to 4.7% and was dispersed mainly in the forest behind Namhansan elementary school. Pinus densiflora going on the ecological succession is distributed a portion of 2.9%. And the currently dying out Pinus densiflora forest amounted to 2.1%. As a result of analysis of the vegetation structure for 19 years, the succession from Pinus densiflora forest to Pinus densiflora and succession from Quercus spp. mixed forest to Quercus spp. forest to Carpinus laxiflora forest were predicted. Additionally, Quercus spp. expanded its dominance over time. According to the characteristics of each classified zone, the site was categorized into $553,508m^2$ area of Pinus densiflora forest area for the landscape maintenance, $114,293m^2$ area of Pinus densiflora forest area for the landscape restoration, $205,306m^2$ area of Pinus densiflora forest area for the disclimax, and $1,169,973m^2$ area of Pinus densiflora forest area for inducing ecological succession.
Journal of Korean Society of Coastal and Ocean Engineers
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v.29
no.2
/
pp.109-120
/
2017
A discounted cost model for preventive maintenance of armor units of rubble-mound breakwaters is mathematically derived by combining the deterioration model based on a discrete-time stochastic process of shock occurrence with the cost model of renewal process together. The discounted cost model of condition-based maintenance proposed in this paper can take into account the nonlinearity of cumulative damage process as well as the discounting effect of cost. By comparing the present results with the previous other results, the verification is carried out satisfactorily. In addition, it is known from the sensitivity analysis on variables related to the model that the more often preventive maintenance should be implemented, the more crucial the level of importance of system is. However, the tendency is shown in reverse as the interest rate is increased. Meanwhile, the present model has been applied to the armor units of rubble-mound breakwaters. The parameters of damage intensity function have been estimated through the time-dependent prediction of the expected cumulative damage level obtained from the sample path method. In particular, it is confirmed that the shock occurrences can be considered to be a discrete-time stochastic process by investigating the effects of uncertainty of the shock occurrences on the expected cumulative damage level with homogeneous Poisson process and doubly stochastic Poisson process that are the continuous-time stochastic processes. It can be also seen that the stochastic process of cumulative damage would depend directly on the design conditions, thus the preventive maintenance would be varied due to those. Finally, the optimal periods and scale for the preventive maintenance of armor units of rubble-mound breakwaters can be quantitatively determined with the failure limits, the levels of importance of structure, and the interest rates.
A chicken clathrin-associated adaptor protein $3-{\delta}$ subunit 2 (AP3S2) is a subunit of AP3, which is involved in cargo protein trafficking to target membrane with clathrin-coated vesicles. AP3S2 may play a role in virus entry into host cells through clathrin-dependent endocytosis. AP3S2 is also known to participate in metabolic disease developments of progressions, such as liver fibrosis with hepatitis C virus infection and type 2 diabetes mellitus. Chicken AP3S2 (chAP3S2) gene was originally identified as one of the differentially expressed genes (DEGs) in chicken kidney which was fed with different calcium doses. This study aims to characterize the molecular characteristics, gene expression patterns, and transcriptional regulation of chAP3S2 in response to the stimulation of Toll-like receptor 3 (TLR3) to understand the involvement of chAP3S2 in metabolic disease in chicken. As a result, the structure prediction of chAP3S2 gene revealed that the gene is highly conserved among AP3S2 orthologs from other species. Evolutionarily, it was suggested that chAP3S2 is relatively closely related to zebrafish, and fairly far from mammal AP3S2. The transcriptional profile revealed that chAP3S2 gene was highly expressed in chicken lung and spleen tissues, and under the stimulation of poly (I:C), the chAP3S2 expression was down-regulated in DF-1 cells (P<0.05). However, the presence of the transcriptional inhibitors, BAY 11-7085 (Bay) as an inhibitor for nuclear factor ${\kappa}B$ ($NF{\kappa}B$) or Tanshinone IIA (Tan-II) as an inhibitor for activated protein 1 (AP-1), did not affect the expressional level of chAP3S2, suggesting that these transcription factors might be dispensable for TLR3 mediated repression. These results suggest that chAP3S2 gene may play a significant role against viral infection and be involved in TLR3 signaling pathway. Further study about the transcriptional regulation of chAP3S2 in TLR3 pathways and the mechanism of chAP3S2 upon virus entry shall be needed.
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