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An Experimental Study on Evaporative Heat Transfer Characteristics in a Small Diameter Tube (미소직경관 내 증발열전달 특성에 관한 실험적 연구)

  • Hwang, Yun-Uk;Kim, Min-Su
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.2
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    • pp.216-224
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    • 2001
  • Experiments have been performed to investigate evaporative heat transfer characteristics of R-134a flowing in a small diameter tube. Test section was made of stainless steel tube with an inner diameter of 2.2mm and was uniformly heated by electric current which was applied to the tube wall. The local saturation temperature of refrigerant flowing in a tube is calculated from the measured local saturation pressure by using an equation of state. Inner wall temperature was calculated from measured outer wall temperature, accounting for heat generation in the tube and one dimensional heat conduction through the tube wall. Mass quality of refrigerant flowing in a tube was calculated by considering energy balance in the pre-heater and the test section. Heat flux was varied from 19 to 64kW/$m^2$, and mass flux was chanted from 380 to 570kg/$m^2$s for each heat flux condition. From this study, heat transfer in a small diameter tube is affected by heat flux as well as mass flux for a wide range of mass quality. Heat transfer coefficient in a small diameter tube is much greater than that in medium sized tubes. Test results in this study are compared with Gungor and Winterton correlation, which gives an absolute average deviation of 27%.

A Study on the Binary-Coded Physical-Layer Network Coding with High-Order Modulation Techniques (고차원 변조방식을 적용한 이진 부호화된 물리계층 네트워크 코딩에 관한 연구)

  • Lim, Hyeonwoo;Ban, Tae-Won;Jung, Bang Chul
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.9
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    • pp.2131-2139
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    • 2014
  • In this paper, a binary-coded physical-layer network coding (PNC) is considered when high-order modulation techniques are used at source nodes in wireless communication environments. In the conventional PNC schemes, tight power control and phase compensation are required at a relay node. However, they may not be feasible in practical wireless communication environments. Thus, we do not assume the pre-equalization in this paper, and we only utilize the channel state information at receiver (CSIR). We propose a signal detection method for the binary-coded PNC with high-order modulation, such as QPSK and 16QAM, at the source nodes, while the conventional scheme only consider the BPSK at source nodes. We also analyze the bit-error performance of the proposed technique in both uncoded and coded cases.

GABAB Receptor Modulation on the Antinociception of Intrathecal Sildenafil in the Rat Formalin Test (쥐의 포르말린 시험에서 척수강 Sildenafil의 항통각효과에 대한 GABAB 수용체 조절성)

  • Kim, Woong Mo;Yoon, Myung Ha;Lee, Hyung Gon;Han, Yong Gu;Kim, Yeo Ok;Huang, Lan Ji;Cui, Jin Hua
    • The Korean Journal of Pain
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    • v.20 no.2
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    • pp.106-110
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    • 2007
  • Background: A phosphodiesterase 5 inhibitor, sildenafil, has been effective against nociception. Several lines of evidence have demonstrated the role of the GABAergic pathway in the modulation of nociception. The impact of the GABA receptors on sildenafil was studied using the formalin test at the spinal level. Methods: Male SD rats were prepared for intrathecal catheterization. The formalin test was induced by subcutaneous injection of formalin solution. The change in the activity of sildenafil was examined after pre-treatment with GABA receptor antagonists ($GABA_A$ receptor antagonist, bicuculline; $GABA_B$ receptor antagonist, saclofen). Results: Intrathecal sildenafil dose-dependently attenuated the flinching observed during phase 1 and 2 in the formalin test. The antinociceptive effect of sildenafil was reversed by the $GABA_B$ receptor antagonist (saclofen) but not by the $GABA_A$ receptor antagonist (bicuculline) in both phases. Conclusions: Intrathecal sildenafil suppressed acute pain and the facilitated pain state. The antinociception of sildenafil is mediated via the $GABA_B$ receptor, but not the $GABA_A$ receptor, at the spinal level.

A Study on Shrinkage the Weft Knitted Fabrics (위편포의 수축에 관한 연구)

  • Sung Baek Joo;Choi Suk Chul;Chung Soon Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.4 no.1_2
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    • pp.25-33
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    • 1980
  • The studies on shrinkage and characteristics of the weft knitted fabrics were investigated under the various dry and wet treating conditions. Various relaxation values were found out according to treating conditions. The characteristics of knitted fabrics such as shrinkage rate, thickness, spirality, elongation and recovery were also measured. The used knitting yams were OE (open-end) cotton and POY (pre-oriented yarn)-DTY (draw textured yam) polyester. The conclusions obtained in this study are as follows. 1. In case of dry relaxation little change of Ks values was seen with increasing time after 48 hours. So it was found that relaxation shrinkage of dry relaxation reached its maximal state in about 48 hours. 2. In case of wet relaxation, higher Ks values were observed, in comparision with those of dry one and higher shrinkage rates were also observed. But when experimental temperature was constant, sudden marked increases in Ks values and shrinkage rates appeared through the initial 4 hours, and after that time little change was seen in them. 3. As Ks value increases, thickness also increased. But thickness showed to some degree stability around Ks value 23. 4. As Ks value increases, spirality values also increased gradually. But little change of spirality values was observed above a certain Ks values (cotton 22.5, polyester 21.5). 5. As Ks value increases, the elongation decreased under a certain load, and the recovery was random.

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Antioxidant and Anti-Inflammatory Effects of Various Cultivars of Kiwi Berry (Actinidia arguta) on Lipopolysaccharide-Stimulated RAW 264.7 Cells

  • An, Xiangxue;Lee, Sang Gil;Kang, Hee;Heo, Ho Jin;Cho, Youn-Sup;Kim, Dae-Ok
    • Journal of Microbiology and Biotechnology
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    • v.26 no.8
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    • pp.1367-1374
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    • 2016
  • The present study evaluated the total phenolic and flavonoid contents as well as total antioxidant capacity (TAC) of three cultivars of Actinidia arguta Planch. kiwi berries; cv. Mansoo (Mansoo), cv. Chiak (Chiak), and cv. Haeyeon (Haeyeon). In addition, the anti-inflammatory effects of the three cultivars of kiwi berries were investigated using a lipopolysaccharide (LPS)-stimulated RAW 264.7 murine macrophage cell line. Mansoo had the highest total phenolic content and TAC among the three cultivars, whereas Chiak had the highest total flavonoid content. The total antioxidant capacities of the kiwi berry extracts were more strongly correlated with total phenolic content than with total flavonoid content. The kiwi berry extracts suppressed the secretion of pro-inflammatory cytokines, including interleukin-6 and tumor necrosis factor-α, from LPS-stimulated RAW 264.7 cells. The release of nitrite, an indirect indicator of nitric oxide, was also ameliorated by pre-treatment with the kiwi berry extracts in a dose-dependent manner. Cellular-based measurements of antioxidant capacity exhibited that the kiwi berry extracts had cellular antioxidant capacities. Such cellular antioxidant effects are possibly attributed to their direct antioxidant capacity or to the inhibition of reactive oxygen species generation via anti-inflammatory effects. Our findings suggest that kiwi berries are potential antioxidant and anti-inflammatory agents.

Analytical and Field Investigation of Bridge Stress Distribution under Proof Load (기지하중을 받는 교량구조물의 현장 계측 및 해석에 따른 응력분포 연구)

  • Eom, Jun-Sik;Lho, Byeong-Cheol
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.7 no.3
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    • pp.139-146
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    • 2003
  • The objective of the presented study is to develop an efficient procedure of proof load testing for existing bridges. By analytical methods, some of these bridges are not adequate to carry normal highway traffic. However, the actual load carrying capacity is often much higher than what can be determined by conventional analysis. Proof load testing can reveal the hidden strength reserve and thus verify the adequacy of the tested bridge. Proof load level required for meaningful tests should be sufficiently higher than legal load. In the state of Michigan, the legal 11-axle truck can weigh up to 685 kN. In this study, a combination of two military tanks and two Michigan 11-axle trucks was used. The proof loads were gradually increased to ensure the safety of the test. After each move, measurements were taken. For the considered bridge, stress levels were rather low compared to pre-test analysis results. This is due to incorrect material strength, structural contribution of nonstructural components such as parapets and railings, and partially fixed supports.

A Study on the Impact of CO2 Immersion Test for Rubber Sealing Materials (고무 씰링 재료에 대한 CO2 침지 영향에 관한 고찰)

  • Seo, Doo-Hyoun;Jang, Kap-Man;Lee, Jin-Han;Rhie, Kwang-Won
    • Journal of the Korean Institute of Gas
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    • v.18 no.5
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    • pp.26-32
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    • 2014
  • CCS(Carbon Capture and Storage) which is technic to capture and storage the carbon-dioxide is the method that reduces the carbon-dioxide from the industries to prevent earth from the global warming. In order to apply to the practical site, it is inevitable to investigate the possibility of damage in the pipe or components by carbon-dioxide. In this paper, the immersion test is performed to estimate the suitability of the rubber which is used to seal or connect the pipelines because the rubber has not been validated. Also, the immersion test is carried out in a certain condition(pre- and supercritical state).

Differentiation of Human Mesenchymal Stem Cells towards Neuronal Lineage: Clinical Trials in Nervous System Disorders

  • Hernandez, Rosa;Jimenez-Luna, Cristina;Perales-Adan, Jesus;Perazzoli, Gloria;Melguizo, Consolacion;Prados, Jose
    • Biomolecules & Therapeutics
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    • v.28 no.1
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    • pp.34-44
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    • 2020
  • Mesenchymal stem cells (MSCs) have been proposed as an alternative therapy to be applied into several pathologies of the nervous system. These cells can be obtained from adipose tissue, umbilical cord blood and bone marrow, among other tissues, and have remarkable therapeutic properties. MSCs can be isolated with high yield, which adds to their ability to differentiate into non-mesodermal cell types including neuronal lineage both in vivo and in vitro. They are able to restore damaged neural tissue, thus being suitable for the treatment of neural injuries, and possess immunosuppressive activity, which may be useful for the treatment of neurological disorders of inflammatory etiology. Although the long-term safety of MSC-based therapies remains unclear, a large amount of both pre-clinical and clinical trials have shown functional improvements in animal models of nervous system diseases following transplantation of MSCs. In fact, there are several ongoing clinical trials evaluating the possible benefits this cell-based therapy could provide to patients with neurological damage, as well as their clinical limitations. In this review we focus on the potential of MSCs as a therapeutic tool to treat neurological disorders, summarizing the state of the art of this topic and the most recent clinical studies.

The Effects of Trunk Stabilization Exercise on the Back Pain Disability Index in Chronic Low Back Pain (체간 안정화 운동이 만성 요통환자의 요통장애지수에 미치는 영향)

  • Kim, Hyoung-Su;Lee, Keun-Heui;Bae, Sung-Soo
    • Journal of the Korean Society of Physical Medicine
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    • v.3 no.3
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    • pp.193-202
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    • 2008
  • Purpose : This study was performed for effects of intervention of mat & ball exercise, sling exercise, and general intervention. The purpose of this study was to know influenced on the change of Oswestry back pain disability index (OBPDI) with chronic low back pain(CLBP) patients. Methods : Three groups of CLBP patients(n=53) were allocated randomly in this study experimental group I (mat & ball exercise group MBE, n=18), experimental group II(sling exercise group SE, n=18) and control group(general intervention, n=17). Intervention was provided 6 weeks(S days a week). Experimental group was provided 3 set a day(10 time/ 1 set, 10sec holding and 10sec resting/ 1 time). The following was the result of the data analysis about OBPDI experiment that had been carried on a week, 2 weeks, 3 weeks, 4 weeks, S weeks, 6 weeks after, and even comparing with pre-experimental state. Results : The results were as follows. OBPDI about intervention period had decrease in the MBE and the SE groups. but there was no difference in the control group. Among three groups, The MBE and the SE groups had difference compare with control group. This shows that the MBE and the SE groups had effective decrease pain and disability. Conclusion : Therefore, this study shows that trunk stabilization exercise program influenced on the change of OBPDI with CLBP patients.

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Intelligent Digital Redesign of Observer-Based Output-Feedback Fuzzy Controller Using Delta Operator (델타 연산자를 이용한 관측기 기반 출력 궤환 퍼지 제어기의 디지털 재설계)

  • Moon, Ji Hyun;Lee, Ho Jae;Kim, Do Wan
    • Journal of the Korean Institute of Intelligent Systems
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    • v.22 no.6
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    • pp.700-705
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    • 2012
  • This paper addresses an intelligent digital redesign (IDR) technique for observer-based output-feedback control systems, in order to efficiently convert a pre-designed Takagi-Sugeno fuzzy model-based analog controller into a sampled-data one in the sense of state matching. A delta operator is used to get an asymptotic relation between the analog and the sampled-data control systems. The IDR problem is viewed as a minimization problem of the norm distances between linear operator to be matched. The condition is represented as linear matrix inequalities, and the separation principle on the IDR is shown.