• Title/Summary/Keyword: pre-state

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Orbital Volume Change Resulted from Packing in Ethmoidal Sinus for Correction of Isolated Medial Orbital Fractures (안와내벽파열골절의 내시경적 사골동내 충전에 따른 안와용적 변화)

  • Kim, Kyoung-Hoon;Choi, Soo-Jong;Kang, Cheol-Uk;Bae, Yong-Chan;Nam, Su-Bong
    • Archives of Craniofacial Surgery
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    • v.10 no.1
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    • pp.7-13
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    • 2009
  • Purpose: Endoscopic transnasal correction of the medial orbital fractures cannot be enable to confirm the reduction degree of orbital volume without imaging modalities. We have intended through this study to make a quantative analysis of preoperative orbital volume increment and the reduction degree of that after ethmoidal sinus packing by using CT scan. Methods: In this retrospective study, 22 patients were selected to evaluate the postoperative volume reduction, who took 2 CT scans which are pre- and postoperative under the same protocol. The postoperative CT scan was carried out in about 5 days after the operation with the packing inserted into ethmoidal sinus. The length of bony defect on each section was measured by PACS program and the area of defect was calculated by summing lengths on each section multiplied by the thickness of the section. When the outline of orbit on the slice is drawn manually with a cursor, PACS program measures the area automatically. Orbital volume was calculated from the sum of the area multiplied by the section thickness. Results: The mean dimension of fractured walls was $2.86{\pm}0.99cm^2$. The mean orbital volume of the unaffected orbits was $22.89{\pm}2.15cm^3$ and that of the affected orbits was $25.62{\pm}2.82cm^3$. The mean orbital volume increment of the affected orbits was $2.73{\pm}1.13cm^3$. After surgery, the mean orbital volume of the unaffected orbits was $22.46{\pm}2.73cm^3$ and the mean orbital volume decrease on the surgical side was $2.98{\pm}1.07cm^3$. The estimated correction rate was 118.30%. Conclusion: The orbital volume increment in fractured orbit showed linear correlation with the dimension of fractured area. The orbital volume changes after ethmoidal sinus packing also showed linear correlation with orbital volume increment in fractured orbit. This study showed the regressive linear correlation between the increment of orbital volume and the correction rate. To evaluate the maintenance of reduction state, we think that the further study should be done for comparative analysis of orbital volume change after removal of packing.

Optimal effect-site concentration of remifentanil to prevent hemodynamic changes during nasotracheal intubation using a video laryngoscope

  • Yoon, Ji-Young;Park, Chul-Gue;Kim, Eun-Jung;Choi, Byung-Moon;Yoon, Ji-Uk;Kim, Yeon Ha;Lee, Moon Ok;Han, Ki Seob;Ahn, Ji-Hye
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.20 no.4
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    • pp.195-202
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    • 2020
  • Background: Nasotracheal intubation is the most commonly used method to secure the field of view when performing surgery on the oral cavity or neck. Like orotracheal intubation, nasotracheal intubation uses a laryngoscope. Hemodynamic change occurs due to the stimulation of the sympathetic nervous system. Recently, video laryngoscope with a camera attached to the end of the direct laryngoscope blade has been used to minimize this change. In this study, we investigated the optimal effect-site concentration (Ce) of remifentanil for minimizing hemodynamic responses during nasotracheal intubation with a video laryngoscope. Methods: Twenty-one patients, aged between 19 and 60 years old, scheduled for elective surgery were included in this study. Anesthesia was induced by slowly injecting propofol. At the same time, remifentanil infusion was initiated at 3.0 ng/ml via target-controlled infusion (TCI). When remifentanil attained the preset Ce, nasotracheal intubation was performed using a video laryngoscope. The patient's blood pressure and heart rate were checked pre-induction, right before and after intubation, and 1 min after intubation. Hemodynamic stability was defined as an increase in systolic blood pressure and heart rate by 20% before and after nasotracheal intubation. The response of each patient determined the Ce of remifentanil for the next patient at an interval of 0.3 ng/ml. Results: The Ce of remifentanil administered ranged from 2.4 to 3.6 ng/ml for the patients evaluated. The estimated optimal effective effect-site concentrations of remifentanil were 3.22 and 4.25 ng/ml, that were associated with a 50% and 95% probability of maintaining hemodynamic stability, respectively. Conclusion: Nasotracheal intubation using a video laryngoscope can be successfully performed in a hemodynamically stable state by using the optimal remifentanil effect-site concentration (Ce50, 3.22 ng/ml; Ce95, 4.25 ng/ml).

THE CEPHALOMETRIC ANALYSIS OF THE SOFT TISSUE CHANGES AT THE MIDDLE FACE IN THE SKELETAL CLASS III PATIENTS WITH THE ORTHOGNATHIC 2-JAW SURGERY (골격성 제3급 부정교합자의 양악 수술 후 중안면부 연조직 변화에 관한 두부 계측 방사선학적 연구)

  • Ahn, Je-Young;Kim, Ji-Yong;Joo, Bum-Ki;Kim, Min-Chul;Huh, Jong-Ki;Kim, Hyung-Gon;Park, Kwang-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.1
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    • pp.21-26
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    • 2006
  • Considering the skeletal class III malocclusion that complains of mandibular prognathism, there have been some studies of the mandibular change for comparing the changes of pre operative with post operative state. Nowadays it is common to do the orthognathic 2-jaw surgery for the correction of the maxillary deficiency, the post operative stability and the esthetics. We compare and analyze the changes of soft tissue around the nose and the lip with the changes in the direction and the amount of maxilla. Patients who were diagnosed as maxillofacial deformity and received orthognathic surgery of both jaws at Yongdong Severance hospital from 2001 through 2003 were included in this study. Their lateral cephalograms were analyzed, and the post operative change of hard tissue and soft tissue were studied. Upon analyzing the preoperative cephalograms and 6 month post operative cephalograms, there were significant in the vertical change of Labialis superius(Ls) and Stomion(Stm) in soft tissue in relation to the vertical change of skeletal landmarks (Anterior Nasal Spine, Subspinale, Prosthion, Incision Superious). In addition, there were no significance in horizontal movement of the skeletal landmarks among groups. In terms of hard tissue landmarks, group 3(maxillary posterior impaction and advancement surgery group) showed significantly greater change in the vertical movement of Anterior Nasal Spine(ANS), Subspinale(A), Prosthion(Pr), and Incision Superious(Is) compared with other groups. In terms of soft tissue change, group 3 showed more significant change in the vertical movement of Ls and Stm. This study calculated the changes of the skeletal and soft tissue landmarks in order to act as a guide in planning and performing the surgery and as a reference in predicting the postoperative change of facial appearance.

Geographical interpretation of the Chapter on Economy in (財用篇) the Mangiyoram ("만기요람(萬機要覽)" "재용편(財用篇)"의 지리적 해석)

  • Sohn, Yong-Taek
    • Journal of the Economic Geographical Society of Korea
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    • v.12 no.2
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    • pp.195-214
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    • 2009
  • The Mangi yoram("萬機要覽"), a guidebook of state affairs, was published by royal command in the late Joseon period. Its chapters on financial affairs(財用篇) are particularly remarkable, as they explain on all aspects of the national finance of the late Joseon period in a clear manner. The financial part of the Mangi yoram includes metallic mineral resources, such as the location of gold, silver, copper, lead deposits and the prosperity and decline of the mines, and the various uses of each of the minerals. These are still regarded as valuable resources. Its contents on agricultural geography comprise not only the total yearly output of grains, paddyfields and dryfields, their taxation and standards of taxation, but also ginseng which was famous in the outside world in the pre-modern era. The book also clearly explains distribution of agricultural dikes for irrigation and their functions. The book also contains information on forestry geography, e.g. the varieties of pine trees and their distribution and mountain containment policies. Contents related to commercial geography consist of material on different types of markets such as the yukuijeon(六矣廛), sijeon(市廛), peongsisuh(平市署), nanjeon(亂廛), and the distribution, size and prosperity and decline of the border markets of the northern frontier such as the hoeryungkaesi(會寧開市) and geongwonkaesi(慶源開市). Contents related to transport geography are the distribution and functions of government granaries etc. Obviously, this book contains detailed information on various aspects of Korean geography. If we try to understand the contents of this book from the framework of modern geographical classification schemes, the geographic information contained in the book assumes even greater significance. In sum one may conclude that this book, which the king kept by his side, contained useful geography related knowledge and necessary information, and was directly relevant to the administration of the country. It exerted immense influence on the contemporary intellectual world of Joseon Korea, and was regarded as an invaluable resource.

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Influence of Precooling Cooling Air on the Performance of a Gas Turbine Combined Cycle (냉각공기의 예냉각이 가스터빈 복합발전 성능에 미치는 영향)

  • Kwon, Ik-Hwan;Kang, Do-Won;Kang, Soo-Young;Kim, Tong-Seop
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.2
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    • pp.171-179
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    • 2012
  • Cooling of hot sections, especially the turbine nozzle and rotor blades, has a significant impact on gas turbine performance. In this study, the influence of precooling of the cooling air on the performance of gas turbines and their combined cycle plants was investigated. A state-of-the-art F-class gas turbine was selected, and its design performance was deliberately simulated using detailed component models including turbine blade cooling. Off-design analysis was used to simulate changes in the operating conditions and performance of the gas turbines due to precooling of the cooling air. Thermodynamic and aerodynamic models were used to simulate the performance of the cooled nozzle and rotor blade. In the combined cycle plant, the heat rejected from the cooling air was recovered at the bottoming steam cycle to optimize the overall plant performance. With a 200K decrease of all cooling air stream, an almost 1.78% power upgrade due to increase in main gas flow and a 0.70 percent point efficiency decrease due to the fuel flow increase to maintain design turbine inlet temperature were predicted.

Acupuncture on Siguan Points (LI4 and LR3) Restores Loperamide/Scopolamine-induced Intestinal Immotility in Mice

  • Shin Jang-Woo;Son Jin-Young;Yim Yun-Kyoung;Choi Sun Mi;Koo Sung-Tae;Son Chang-Gue
    • The Journal of Korean Medicine
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    • v.27 no.1 s.65
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    • pp.146-154
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    • 2006
  • Objectives : Siguan points (LI4, LR3) have been most frequently applied for various diseases, especially different digestive disorders such as constipation, abdominal pain or various intestinal inflammatory diseases. The fact that gastrointestina movement is closely connected with physiologic functions or pathologic process of alimentary canal led us to ask the question if Siguan points affects on intestinal motility. Design: To investigate the effect of Siguan acupuncture on the intestinal movement in both physiologic and pathologic conditions, we divided the experimental animals into 12 groups. Six groups were pre-treated with loperamide (0.5 mg/kg, sc) or scoploamine (0.5 mg/kg, sc) to suppress the intestinal movement and another three groups were pretreated with carbachol (0.5 mg/kg, po) to activate it, whereas the rest three groups didn't receive any pretreatment to be kept in the physiological condition. After the administration with charcoal meal, mice were acupunctured bilaterally on sham point or Siguan points as the manner of tap-stimulation, with the exception of no acupuncture groups. Methods : Mice were scarified in twenty minutes after the administration of charcoal to measure the distance of charcoal passage from stomach-duodenal junction. The effect on intestinal movement was presented by calculating the relative distance where charcoal arrived to total length of small intestine. Results : In physiological state, charcoal meal passed around 53%, and there was no significant difference between Siguan points and sham points groups. On the other hand. Siguan points-sitimulation significantly ameliorated loperamide or scoplolamine-induced suppressed travel rate of 17.3 % and 18.6% in sham point into 26% and 26.3% respectively (p<0.05). In carbachol-induced accelerated condition, Siguan points-stimulation didn't affect intestinal motility comparing to sham point group passed about 97.6%. Conclusions : These results postulate that acupuncture at Siguan points have a therapeutic effect by restoring cholinergic activity on pathogenically suppressed intestinal peristalsis, but does not affect the gastrointestinal motility in the normal or accelerated condition.

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The effects of Fire point(LR2).Water point(LR8) through Reinforcement-Reduction acupuncture stimulation on ANS & EEG (족궐음간경(足厥陰肝經)의 화혈(火穴)과 수혈(水穴)의 침보사(針補瀉)가 자율신경계와 뇌파에 미치는 영향)

  • Kang, Hee-Chul;Lee, Seung-Gi
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.2
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    • pp.87-101
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    • 2010
  • Objectives : The aim of this experiment was to investigate the influences of Autonomic Nervous System and EEG by conducting Reinforcement-Reduction(補瀉) acupuncture stimulation to compare the changes in acupoints on the body before and after treatment of acupuncture at Xingjian(LR2) being referred as Fire-point(火穴) and Ququan(LR8) being referred as Water-point(水穴) of Yin Liver Meridian(足厥陰肝經). Methods : This study was carried out on 30 healthy female volunteers in their 20's. There were four tests conducted throughout and the period for each test was between 2 to 5days. HRV and EEG were measured for 5 minutes before acupuncture stimulation was conducted on LR2-Reinforcement, LR2-Reduction, LR8-Reinforcement and LR8-Reduction at random. During the 20 minutes of acupuncture treatment, same subjects were measured simultaneously to observe any significant changes in acupoints. Again, the same subjects were measured for 5 minutes after removing the acupuncture in order to perform a comparative analysis. Results : The measurement of HRV showed that LF, LFnorm and LF/HF ratio increased significantly(p<0.05) while HF, HF norm decreased significantly in case of LR2-Reinforcement & LR8-Reduction. Both LR2-Reduction and LR8-Reinforcement induced a significant increase in HFnorm. EEG measurement indicated low $\alpha$ wave decreased and high $\beta$ wave increased significantly at LR2-Reinforcement during post-acupuncture period compared with acupuncture stimulation period. Both LR2-Reduction and LR8-Reinforcement developed significantly low $\alpha$ wave and high $\alpha$ wave. High $\beta$ wave increased significantly at LR8-Reduction during the acupuncture stimulation in comparison with pre-acupuncture period. Conclusions : The manipulation of acupuncture stimulation at LR2-Reinforcement and LR8-Reduction enhanced the activity of sympathetic nerves and the state of arousal while that of para sympathetic nerves declined. On the other hand, LR2-Reduction and LR8-Reinforcement developed the levels of para sympathetic nerves and relaxation.

Nonlinear Moment-Curvature Relations and Numerical Structural Analysis of High-Strength PSC Flexural Members (고강도 PSC 휨부재의 비선형 모멘트-곡률 관계와 전산구조해석)

  • 연정흠;이제일
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.15 no.1
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    • pp.95-104
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    • 2002
  • A methods to calculate non-linear moment-curvature relations of high-strength PSC flexural members for numerical analysis has been proposed. The moment-curvature relations were calculated with assumptions of design codes and by the layer method. The results of the proposed procedures for moment-curvature relations and numerical analysis were compared with those of pre-existing tests. The absorption energy rate of the design codes was about 30% larger than that of the layer method. The ultimate load and the external work of the layer method were 90% and 85% of those of tests, respectively The ultimate load of the strength design method was 97% of that of tests, but the external work was over-estimated with 122%. The ultimate load and external work by the proposed equation of the CEB-FIP Model Code were 113% and 173% of those of tests, respectively. It show that the use of ultimate strain of 0.0035 should be over-estimated for high-strength concrete. The procedure of non-linear numerical analysis of this research could be stably simulated the behavior of concrete flexural members until the ultimate state, and calculate results of the load-deflection relation and cracking pattern were very similar with those of tests.

The Effect of Cucumber mosaic virus 2b Protein to Transient Expression and Transgene Silencing Mediated by Agro-infiltration

  • Choi, Min-Sue;Yoon, In-Sun;Rhee, Yong;Choi, Seung-Kook;Lim, Sun-Hyung;Won, So-Youn;Lee, Yeon-Hee;Choi, Hong-Soo;Lee, Suk-Chan;Kim, Kook-Hyung;Lomonossoff, George;Sohn, Seong-Han
    • The Plant Pathology Journal
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    • v.24 no.3
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    • pp.296-304
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    • 2008
  • The transient and rapid expression system of a foreign protein in planta is a very useful technique in biotechnology application. We have investigated optimum condition of Agrobacterium-infiltration technique in which expression level of foreign proteins were maximized without detrimental effects on plants using GFP and Cucumber mosaic virus 2b protein, which is known as an enhancer of gene expression and a suppressor of post-transcriptional gene silencing(PTGS). The optimum expression level of both RNA and protein of GFP with minimum leaf impairment was obtained at $OD_{600}$=0.2 of Agrobactrium inocula. The steady-state levels of GFP RNA and protein generally peaked at 3 and 7 days post-infiltration(dpi), respectively. In the presence of 2b, both the magnitude and duration of GFP expression was highly increased and we could detect GFP level until 17 dpi. On the other hands, the 2b-mediated higher accumulation of foreign proteins resulted in the repression of normal leaf growth, possibly due to the limitation of supply of energy or materials required for growth maintenance. Using this Agrobacterium-infiltration system with 2b and GFP, we tested a hypothesis for the threshold model of PTGS initiation. Four GFP transgenic lines of N. benthamiana, which shows different expression level of GFP were tested to determine the threshold level for PTGS initiation. Agrobacterium-infiltration of GFP into those GFP-transgenic plants resulted in the co-silencing of the transgenic GFP. It was found that very low concentration of Agrobacterium with GFP and GFP+2b($OD_{600}$=0.002-0.02) which could not phenotypically induce an additive GFP expression, was enough to trigger PTGS pathway in all GFP transgenic plants. This strongly indicates that each GFP-transgenic plant should be expressing the transgenic GFP at its own pre-determined level and there was no buffer zone of additive GFP-expression to the threshold. In other words, the PTGS seems to be immediately activated as a self-defensive mechanism if an internal balance of gene expression is broken.

The Effects of Coaching-Based Personality Education Program on the Improvement of Personality in Elementary School Students (코칭기반 인성교육 프로그램이 초등학생의 인성향상에 미치는 효과)

  • Choi, In-Sook;Chae, Myungsin
    • Journal of the Korea Convergence Society
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    • v.9 no.9
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    • pp.229-243
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    • 2018
  • The purpose of this study is to develop a personality education program that can enhance the virtues of elementary school students, self-esteem, Consideration communication, self-control, honesty courage by using coaching methodologically, To improve the personality virtue. The subjects of this study were 31 students from 4th grade of U elementary school in S Gu, Seoul. The experimental group was divided into 16 sessions, weekly from March 5, 2018 to June 30, 2018, 1 hour (40 minutes). The program consisted of items such as self-esteem, Consideration communication, self-control, honesty courage among the personality virtues of KEDI personality test, Each activity used a tough coaching model developed by combining the GROW model with the Empowering model and considering the developmental level of elementary school students. As a result, all four virtues of personality were significantly improved, model with the Empowering model and considering the developmental level of elementary school students. We compared pre and post test result with paired t-test. As a results, the experimental group showed improvement in all four virtues of personality at 0.05 significance level, whereas the control group did not. This suggests that the program can be usefully used as a tool to improve four virtues of personality of elementary school students. For further research, we expect that the program would be integrated with state-of-art technology such as online program or CBI(Computer-Based Instruction).