• The Journal of Korean Physical Therapy
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• v.23 no.1
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• pp.37-43
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• 2011

Purpose: We studied the changes in motor response time and stop signal response time following visuomotor skill learning of a stop signal task in young healthy subjects. This study also was designed to determine what an effective practice is for different stop signals in the stop signal task (SST). Methods: Forty-five right-handed normal volunteers without a history of neurological dysfunction were recruited. They all gave written informed consent. In all subjects, motor reaction time (RT) and stop signal reaction time (SSRT) were measured for the stop signal task. Tasks were classified into three categories: predictable-stop signal task (P-SST) practice group random-stop signal task (R-SST) practice group control group. Results: Motor reaction time in the P-SST was significantly reduced when comparing pre- and post-tests (p<0.05). Stop signal reaction times in the P-SST and the R-SST were significantly reduced following motor skill learning (p<0.05). Also, the reaction time of the R-SST was shorter than that of the P-SST. Conclusion: These findings indicate that practice of an SST improves motor performance and stop function for some stop signals in the SST. P-SST practice was effective in the stop function of regular movement because of faster of the motor prediction and preparation but the R-SST was effective in the stop function of movements because of faster motor selection.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.6
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• pp.2781-2785
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• 2016

Background: Matric metalloproteinase (MMP) 13 gene expression is increased in esophageal squamous cell carcinomas (ESCCs) and associated with increasing tumor invasion, lymph node involvement and decreased survival rates. Levels of the circulating enzyme may be elevated and used as a marker of tumor progression. In this study, clinical application of MMP-13 serum levels was evaluated for early detection, prediction of prognosis and survival time of ESCC patients. Materials and Methods: Serum levels of MMP13 were determined by ELISA in 66 ESCC patients prior of any treatment and 54 healthy controls for comparison with clinicopathological data through statistical analysis with Man Whitney U and Log-Rank tests. In addition, clinical value of MMP13 levels for diagnosis was evaluated by receiver operating characteristic (ROC) test. Results: The serum level of MMP-13 in patients (>250 pg/ml) was significantly higher than in the control group (<100 pg/ml) (p value=0.004). Also the results showed a significant correlation between MMP-13 serum levels with tumor stage (p value = 0.003), depth of tumor invasion (p value=0.008), involvement of lymph nodes (p value = 0.011), tumor size (p value = 0.018) and survival time. While there were no significant correlation with grade and location of tumors. ROC analysis showed that MMP-13 level is an accurate diagnostic marker especially to differentiate pre-invasive/ invasive lesions from normal controls (sensitivity and specificity: 100%). Conclusions: These findings indicate a potential clinical significance of serum MMP13 measurement for early detection and prognostic assessment in ESCC patients.

• Korean Journal of Remote Sensing
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• v.15 no.3
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• pp.195-208
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• 1999

In the classification of satellite images, the representative of training of classes is very important factor that affects the classification accuracy. Hence, in order to improve the classification accuracy, it is required to optimize pre-classification stage which determines classification parameters rather than to develop classifiers alone. In this study, the normality of training are calculated at the preclassification stage using SPOT XS and LANDSAT TM. A correlation coefficient of multivariate Q-Q plot with 5% significance level and a variance of initial training are considered as an object function of genetic algorithm in the training normalization process. As a result of normalization of training using the genetic algorithm, it was proved that, for the study area, the mean and variance of each class shifted to the population, and the result showed the possibility of prediction of the distribution of each class.

• Atmosphere
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• v.31 no.3
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• pp.341-359
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• 2021

This technical note introduces the new Korea Meteorological Administration (KMA) Global Seasonal forecasting system version 6 (GloSea6) to provide a reference for future scientific works on GloSea6. We describe the main areas of progress and improvements to the current GloSea5 in the scientific and technical aspects of all the GloSea6 components - atmosphere, land, ocean, and sea-ice models. Also, the operational architectures of GloSea6 installed on the new KMA supercomputer are presented. It includes (1) pre-processes for atmospheric and ocean initial conditions with the quasi-real-time land surface initialization system, (2) the configurations for model runs to produce sets of forecasts and hindcasts, (3) the ensemble statistical prediction system, and (4) the verification system. The changes of operational frameworks and computing systems are also reported, including Rose/Cylc - a new framework equipped with suite configurations and workflows for operationally managing and running Glosea6. In addition, we conduct the first-ever run with GloSea6 and evaluate the potential of GloSea6 compared to GloSea5 in terms of verification against reanalysis and observations, using a one-month case of June 2020. The GloSea6 yields improvements in model performance for some variables in some regions; for example, the root mean squared error of 500 hPa geopotential height over the tropics is reduced by about 52%. These experimental results show that GloSea6 is a promising system for improved seasonal forecasts.

• Journal of the Korean Geosynthetics Society
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• v.17 no.4
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• pp.129-139
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• 2018

The Discrete Element Method (DEM) has been widely used in granular material researches. Especially, if material has a large deformation, such as ground, it can be a useful method to analyze. In this study, to simulate ground formations, DEM was used. The main purpose of DEM analysis was to investigate the numerical model which can predict the TBM performance by simulating excavating procedure. The selected EPB TBM has a 7.73 m of diameter and six spokes. And two pre-defined excavation conditions with the different rotation speeds per minute (RPM) of the cutterhead was applied. In the modeled cutterhead, the open ratio of cutterhead was 21.31% and number of cutters (including disc cutter and cutter bit) was 219. From the results, reaction forces and resistant torques at the cutterhead face and cutting tools, were measured and compared. Additionally the muck discharge rate and accumulated muck discharge by the screw auger were evaluated.

• Journal of Environmental Science International
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• v.27 no.11
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• pp.957-966
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• 2018

This study intend to induce citizen's voluntary preliminary disaster prevention activity to reduce damage of typhoon that occurs every year. For this purpose, a survey was conducted to develop Typhoon information contents. The number of samples used in the survey was set to 500 people, and citizens living in Jeju, Busan, and Jeonlanam-do were surveyed for areas with high typhoon disasters in order to develop practical and efficient information. The survey consisted of perception about natural disaster, how to get and use weather information, satisfaction with typhoon information and requirements. The general public perceived the typhoon as the first natural disaster. As a result of responding to the method of obtaining and utilizing weather information, the frequency of collecting weather information at the time of issuance of typhoon special report is higher than usual. The purpose of using weather information is clear and the response rate is high for the purpose of disaster prevention. The medium mainly collecting weather information is Internet portal site and mobile phone besides television. The current satisfaction with typhoon weather information is 34.8%, in addition to the accuracy of prediction, it is necessary to improve the information (that is content) provided. Specific responses to the content were investigated not only for single meteorological factors, but also for possible damage and potential countermeasures in the event of a disaster such as a typhoon. As can be seen from the above results, people are requested to provide information that can be used to detect and cope with disasters. The development of new content using easy accessible media will contribute to the reduction of damages caused by the typhoon that will occur in the future, and also to the disaster prevention activity.

• Computers and Concrete
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• v.24 no.2
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• pp.159-172
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• 2019

This paper presents an investigation into the flexural behavior of reinforced concrete (RC) beams retrofitted by ultra-high performance fiber-reinforced concrete (UHPFRC) layers. The experimental study has been conducted in two parts. In the first part, four methods of retrofitting with UHPFRC layers in both the up and down sides of the beams have been proposed and their efficiency in the bonding of the normal concrete and ultra-high performance fiber-reinforced concrete has been discussed. The results showed that using the grooving method and the pre-casted UHPFRC layers in comparison with the sandblasting method and the cast-in-place UHPFRC layers leads to increase the load carrying capacity and the energy absorption capacity and causes high bond strength between two concretes. In the second part of the experimental study, the tests have been conducted on the beams with single UHPFRC layer in the down side and in the up side, using the effective retrofitting method chosen from the first part. The results are compared with those of non-retrofitted beam and the results of the first part of experimental study. The results showed that the retrofitted beam with two UHPFRC layers in the up and down sides has the highest energy absorption and load carrying capacity. A finite element analysis was applied to prediction the flexural behavior of the composite beams. A good agreement was achieved between the finite element and experimental results. Finally, a parametric study was carried out on full-scale retrofitted beams. The results indicated that in all retrofitted beams with UHPFRC in single and two sides, increasing of the UHPFRC layer thickness causes the load carrying capacity to be increased. Also, increases of the normal concrete compressive strength improved the cracking load of the beams.

• Journal of Gastric Cancer
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• v.21 no.2
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• pp.155-168
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• 2021

Purpose: Previous studies have demonstrated the usefulness of the controlling nutritional status (CONUT) score in nutritional assessment and survival prediction of patients with various malignancies. However, its value in advanced gastric cancer (GC) treated with neoadjuvant chemotherapy and curative gastrectomy remains unclear. Materials and Methods: The CONUT score at different time points (pretreatment, preoperative, and postoperative) of 272 patients with advanced GC were retrospectively calculated from August 2004 to October 2015. The χ² test or Mann-Whitney U test was used to estimate the relationships between the CONUT score and clinical characteristics as well as short-term outcomes, while the Cox proportional hazard model was used to estimate long-term outcomes. Survival curves were estimated by using the Kaplan-Meier method and log-rank test. Results: The proportion of moderate or severe malnutrition among all patients was not significantly changed from pretreatment (13.5%) to pre-operation (11.7%) but increased dramatically postoperatively (47.5%). The pretreatment CONUT-high score (≥4) was significantly associated with older age (P=0.010), deeper tumor invasion (P=0.025), and lower pathological complete response rate (CONUT-high vs. CONUT-low: 1.2% vs. 6.6%, P=0.107). Pretreatment CONUT-high score patients had worse progression-free survival (P=0.032) and overall survival (OS) (P=0.026). Adjusted for pathologic node status, the pretreatment CONUT-high score was strongly associated with worse OS in pathologic node-positive patients (P=0.039). Conclusions: The pretreatment CONUT score might be a straightforward index for immune-nutritional status assessment, while being a reliable prognostic indicator in patients with advanced GC receiving neoadjuvant chemotherapy and curative gastrectomy. Moreover, lower pretreatment CONUT scores might indicate better chemotherapy responses.

• The Journal of Engineering Geology
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• v.30 no.4
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• pp.663-671
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• 2020

Recently, there have been many natural disasters in Korea, not only in forest areas but also in urban areas, and the national requirements for them are increasing. In particular, there is no pre-disaster information system that can systematically manage the collapse of the slope of the national highway. In this study, big data analysis was conducted on the factors causing slope collapse based on the detailed investigation report on the slope collapse of national roads in Gangwon-do and Gyeongsang-do areas managed by the Cut Slope Management System (CSMS) and the basic survey of slope failures. Based on the analysis results, a slope collapse risk prediction model was established through Adaboost, a classification-based machine learning model, reflecting the collapse slope location and weather information. It also developed a visualization map for the risk of slope collapse, which is a visualization program, to show that it can be used for preemptive disaster prevention measures by identifying the risk of slope due to changes in weather conditions.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.25 no.1
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• pp.30-40
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• 2022

Purpose: Pediatric acute appendicitis has a stable incidence rate in Western countries with an annual change of -0.36%. However, a sharp increase was observed in the Asian region. The Indonesian Health Department reveals appendicitis as the fourth most infectious disease, with more than 64,000 patients annually. Hence, there is an urgent need to identify and evaluate the risk factors and diagnostic modalities for accurate diagnosis and early treatment. This study also clarifies the usage of pediatric appendicitis score (PAS) for children <5 years of age. Methods: The current study employed a cross-sectional design with purposive sampling through demographic and PAS questionnaires with ultrasound sonography (USG) results. The analysis was performed using the chi-square and Mann-Whitney tests and logistic regression. Results: This study included 21 qualified patients with an average age of 6.76±4.679 years, weighing 21.72±10.437 kg, and who had been hospitalized for 4.24±1.513 days in Siloam Teaching Hospital. Compared to the surgical gold standard, PAS and USG have moderate sensitivity and specificity. Bodyweight and stay duration were significant for appendicitis (p<0.05); however, all were confounders in the multivariate regression analysis. Incidentally, a risk prediction model was generated with an area under the curve of 72.73%, sensitivity of 100.0%, specificity of 54.5%, and a cut-off value of 151. Conclusion: PAS outperforms USG in the sensitivity of diagnosing appendicitis, whereas USG outperforms PAS in terms of specificity. This study demonstrates the use of PAS in children under 5 years old. Meanwhile, no risk factors were significant in multivariate pediatric acute appendicitis risk factors.