• 대한안전경영과학회지
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• 제19권4호
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• pp.133-140
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• 2017

The Ministry of Science, ICT and Future Planning made law for Pre-Hazard Risk Analysis in December 31, 2014 to protect researchers from continuing accidents in laboratory. Conducted before an experiment, Pre-Hazard Risk Analysis finds hazards of the experiment and rules to manage the hazards.So the Pre-Hazard Risk Analysis can support laboratory safety system by prevent accidents in laboratory. Pre-Hazards Risk Analysis is newly created system so that executors need Guidelines to perform this analysis properly. This study is to develop guide tool for Pre-Hazard Risk Analysis by analyzing other risk assessment systems; PSM, Off-site Consequence Assessment, laboratory safety system. Also, this study suggested how to establish database for Pre-Hazard Risk Assessment by analyse KRAS.

• 한국안전학회지
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• 제34권4호
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• pp.85-94
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• 2019

Through the survey on the current status of hazardous substances in laboratories, the research institute is designed to establish measures to improve the management of university laboratories and to create a safe laboratory. We intend to explore countermeasures by confirming and reviewing the recognition of the statutes in the "Guidelines for the Implementation of the Laboratory Pre-Hazard Factors Analysis" through the questionnaire. Although there are various parts to create a pleasant environment for a laboratory, the most important part is the role of a laboratory manager in the area where each and every one of the laboratory's directors is the "Act on the Establishment of a Safety Environment in a Laboratory", but if the laboratory is not to be accident-prone, the laboratory's responsibility is to be more secure. This research is intended to be funded by research to reasonably implement" Guidelines for the Implementation of the Laboratory Pre-Hazard Factors Analysis" before applying to universities and to protect field-based research activities and to reasonably reduce safety accident prevention and risk.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2009년도 학술발표회 초록집
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• pp.2200-2204
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• 2009

In this paper the analysis of natural cause of Beijing Storm inundation and the effect of the human activities has been taken. Flood risk can hardly be eliminated solely by projects. Pre-warning system established is an efficient measure to minimize the influence of flood. Several main functions of this system and their examples are described in the paper, such as: monitoring, forecast, scheme, warning, dynamic decision-making and information publication.

• 한국측량학회:학술대회논문집
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• 한국측량학회 2006년도 춘계학술발표회 논문집
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• pp.339-344
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• 2006

Slope failures are happen to natural disastrous when they occur in mountainous areas adjoining highways in Korea. The accidents associated with slope failures have increased due to rapid urbanization of mountainous areas. Therefore, Regular maintenance is essential for all slope and conducted to maintain road safety as well as road function. In this study, we take priority of making a database of risk factor of the failure of a slope before assesment and analysis. The purpose of this paper is to recommend a standard of Slope Management Information Sheet(SMIS) like as Hazard Map. The next research, we suggest to pre-estimated model of a road slope using Logistic Regression Model.

• 한국식생활문화학회지
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• 제10권3호
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• pp.167-174
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• 1995

A hazard analysis which included watching operations, measuring temperatures of foods throughout preparation and display, and sampling and testing for microorganisms of total plate counts and coliform bacteria was conducted in various phases of product flow of Naeng-myeun (Cold noodles) and Pi-bim bab (mixed rice) prepared at Korean restaurants. Large numbers of total plate counts were counted from the cooked foods after handling and holding. Ingestion of these foods must be considered high risk. Critical control points identified were, pre-preparation, food handling after cooking, and holding on display in product flow of Nang-Meon and pre-preparation, preparation, and holding on display in product flow of Pi-bim bab. It need for effective quality control of Nang-Meon and Pi-bim bab that training program consist of surveillance, education of the staff, standard operation procedures, forbidding dangerous processes and control of critical points.

• 동서간호학연구지
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• 제29권2호
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• pp.106-116
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• 2023

Purpose: The purpose of this study was to identify the impact of obesity on the incidence of diabetes mellitus in adults with pre-diabetes. Methods: This study employed a longitudinal study design and utilized secondary data drawn from the Korean Genome and Epidemiology Study. This study used data from a sample of 3,693 adults with prediabetes who were followed every two years from 2001 to 2018. Statistical data analysis for frequency, number of cases per 1,000 person-years, log-rank test, Kaplan-Meier curve, and Cox's proportional hazards regression analysis was performed using IBM SPSS statistics version 26. Results: During the observation period, there were 1,309 (35.4%) patients with diabetes, and the total number of person-years was 35,342. The incidence of diabetes was higher in the obese group compared to the normal weight group (body mass index [BMI]: hazard ratio=1.57, 95% confidence interval [CI]=1.40~1.77, waist: hazard ratio=1.55, 95% CI=1.38~1.76, waist to hip ratio [WHR]: hazard ratio=1.53, 95% CI=1.24~1.89, body fat [BF] (%): hazard ratio=1.42, 95% CI=1.27~1.61). Conclusion: An increase in BMI, waist circumference, and WHR, which are indicators of obesity, can exacerbate the risk factors for diabetes. Thus, a decrease in BMI, waist circumference, and WHR is necessary to prevent pre-diabetes. In particular, health care professionals should provide individualized weight management program interventions, including adult obesity programs and obesity counseling in partnership with local health departments, to reduce BMI and waist circumference in people at high risk for diabetes.

• 대한공간정보학회지
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• 제14권1호
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• pp.85-91
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• 2006

최근, 사면붕괴는 산악지역에 접해있는 국도변에서 자연재해로 발생하고 있다. 산악지역의 급속한 도로개설, 확장 등 경제개발로 인하여 사면붕괴와 관련된 사고로 직결된다. 따라서, 국도 안전관리와 국도 기능을 유지하기 위하여 모든 사면의 정기점검은 필수적인 사항이다. 본 연구에서는 도로사면을 평가, 분석하기 이전에 사면붕괴 위험요소를 지리정보(GIS) 데이터베이스로 구축하는 것을 우선시 하고 있다. 따라서, 국도 접도사면의 지리정보(GIS) 정보가 수록되어진 사면대장(SMIS) 작성의 표준안을 제안하였다. 그 다음 연구단계로 로지스틱 회귀모형 적용함으로써 접도사면의 위험성을 사전 평가 할 수 있는 모델을 제시하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.166-166
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• 2023

Compound hazards (CHs) are two or more extreme climate events combined which occur simultaneously in the same region at the same time. Compared to individual hazards, the combination of hazards that cause CHs can result in greater economic losses and deaths. While several extreme climate events have been recorded across Asia for the past decades, many studies have only focused on a single hazard. In this study, we assess the spatiotemporal pattern of dry compound hazards which includes drought, heatwave, fire and wind across Asia for the last 42 years (1980-2021) using the historical data from ERA5 Reanalysis dataset. We utilize a daily spatial data of each climate event to assess the occurrence of such compound hazards on a daily basis. Heatwave, fire and wind hazard occurrences are analyzed using daily percentile-based thresholds while a pre-defined threshold for SPI is applied for drought occurrence. Then, the occurrence of each type of compound hazard is taken from overlapping the map of daily occurrences of a single hazard. Lastly, a multivariate assessment are conducted to quantify the occurrence frequency, hotspots and trends of each type of compound hazard across Asia. By conducting a multivariate analysis of the occurrence of these compound hazards, we identify the relationships and interactions in dry compound hazards including droughts, heatwaves, fires, and winds, ultimately leading to better-informed decisions and strategies in the natural risk management.

• Journal of Korean Neurosurgical Society
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• 제54권4호
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• pp.329-335
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• 2013

Objective : Brain metastases in primary breast cancer patients are considerable sources of morbidity and mortality. Gamma knife radiosurgery (GKRS) has gained popularity as an up-front therapy in treating such metastases over traditional radiation therapy due to better neurocognitive function preservation. The aim of this study was to clarify the prognostic factors for local tumor control and survival in radiosurgery for brain metastases from primary breast cancer. Methods : From March 2001 to May 2011, 124 women with metastatic brain lesions originating from a primary breast cancer underwent GKRS at a tertiary medical center in Seoul, Korea. All patients had radiosurgery as a primary treatment or salvage therapy. We retrospectively reviewed their clinical outcomes and radiological responses. The end point of this study was the date of patient's death or the last follow-up examination. Results : In total, 106 patients (268 lesions) were available for follow-up imaging. The median follow-up time was 7.5 months. The mean treated tumor volume at the time of GKRS was 6273 $mm^3$ (range, 4.5-27745 mm3) and the median dose delivered to the tumor margin was 22 Gy (range, 20-25 Gy). Local recurrence was assessed in 86 patients (216 lesions) and found to have occurred in 36 patients (83 lesions, 38.6%) with a median time of 6 months (range, 4-16 months). A treated tumor volume >5000 $mm^3$ was significantly correlated with poor local tumor control through a multivariate analysis (hazard risk=7.091, p=0.01). Overall survival was 79.9%, 48.3%, and 15.3% at 6, 12, and 24 months, respectively. The median overall survival was 11 months after GKRS (range, 6 days-113 months). Multivariate analysis showed that the pre-GKRS Karnofsky performance status, leptomeningeal seeding prior to initial GKRS, and multiple metastatic lesions were significant prognostic factors for reduced overall survival (hazard risk=1.94, p=0.001, hazard risk=7.13, p<0.001, and hazard risk=1.46, p=0.046, respectively). Conclusion : GKRS has shown to be an effective and safe treatment modality for treating brain metastases of primary breast cancer. Most metastatic brain lesions initially respond to GKRS, though, many patients have further CNS progression in subsequent periods. Patients with poor Karnofsky performance status and multiple metastatic lesions are at risk of CNS progression and poor survival, and a more frequent and strict surveillance protocol is suggested in such high-risk groups.

• Clinical Nutrition Research
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• 제11권3호
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• pp.183-193
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• 2022

We investigated the predictors of survival in patients with advanced BTC according to their baseline nutritional status estimated by the Nutritional Risk Screening (NRS)-2002. From September 2006 to July 2017, we reviewed the data of 601 inpatients with BTC. Data on demographic and clinical parameters was collected from electronic medical records, and overall survival (OS) and progression-free survival were analyzed using the Kaplan-Meier method and the stepwise Cox regression analysis. Patients with an NRS-2002 score of ≤ 2, 3, and ≥ 4 were respectively classified as "no risk," "moderate risk," "high risk." Following initial NRS-2002 score, 333 patients (55%) were classified as "no-risk," 109 patients (18%) as "moderate-risk," and 159 patients (27%) as "high-risk." Survival analysis demonstrated significant differences in the median OS: "no-risk": 12.6 months (95% confidence interval [CI], 11.5-13.7); "moderate-risk": 6.1 months (95% CI, 4.3-8.0); and "high-risk": 3.9 months (95% CI, 3.2-4.6) (p < 0.001). NRS-2002 score was an independent factor for OS (hazard ratio [HR], 1.616 for "moderate-risk", 95% CI, 1.288-2.027, p < 0.001; HR, 2.121 for "high-risk", 95% CI, 1.722-2.612, p < 0.001), along with liver metastasis, peritoneal seeding, white blood cell count, platelet count, neutrophil-to-lymphocyte ratio, cholesterol, carcinoembryonic antigen, and carbohydrate antigen 19-9. In conclusion, baseline NRS-2002 is an appropriate method for discriminating those who are already malnourished and who have poor prognosis in advanced BTC patient. Significance of these results merit further validation to be integrated in the routine practice to improve quality of care in BTC patients.