• Title/Summary/Keyword: pre­diction model

Search Result 5, Processing Time 0.022 seconds

Detection of Mycoplasma Infection in Cultured Cells on the Basis of Molecular Profiling of Host Responses

  • Chung, Tae Su;Kim, Ju Han;Lee, Young-Ju;Park, Woong-Yang
    • Genomics & Informatics
    • /
    • v.3 no.3
    • /
    • pp.63-67
    • /
    • 2005
  • Adaptive responses to diverse microbial pathogens might be limited in relatively few types. Host cell responses to pathogens are believed to be patterned or stereotyped along with species or class. We tried to compose the host response to Mycoplasma in terms of cellular gene expression. Although gene expression profile of two host HeLa and 293 cells were quite different each other, 30 genes were differentially expressed by mycoplasma infection in both of HeLa and 293 cells. Six of them (PR48, MADH4, MKPX, CRK, RBM7, NEK3) were related to cell cycle or proliferation. Another category of genes like IL1 HY1, KLRF1, TNFSF14, GBP1 were host defense to elicit immune responses. With this set of genes, we establish the prediction model for mycoplasma contamination.

A Study on the Effects of the Hospitalization Stress on the Sleep Pattern (입원 스트레스가 수면형태에 미치는 영향(Johnson의 간호모형 적용))

  • 이소우
    • Journal of Korean Academy of Nursing
    • /
    • v.16 no.2
    • /
    • pp.36-43
    • /
    • 1986
  • The main purpose of this study was to explore the effect of the stress of hospitalization on the sleep pattern. Additionaly, this study was also to demonstrate how Johnson's nursing model may be applied to as nursing process. 104 hospitalized patients on surgical and medical wards were asked to rate 49 stress producing events associated with experience of hospitalization and sleep pattern scale. Five university hospitals were used as the setting for this study. Data for the study were collected by patient interview during hospitalization, self-reports and review of charts. For the analysis of the data, the pearson's correlation analysis of covariance and regression analysis were used. The results of this study were stated as follows; 1. The mean of the hospital stress scores was 111.261(S.D.=26.160). This means that the level of the hospitalization stress is high. The mean of the sleep pattern scores was 12.204(S.D. =2.615) This means that the characteristic's of the sleep pattern is poor. 2. The relationship between the hospitalization stress and sleep pattern was statistically significant at .01 level. 3. The effect of the hospitalization stress influenced strongly on the sleep pattern after sex, trait anxiety as covariates controlled. 4. The hospitalization stress revealed a 12% pre-diction as an influenced factor for the sleep pattern. Therefore, It can he said that the hospital stress did contribute significantly to the characteristics of the sleep pattern. Johnson's model can he also said that it is useful for the the assessment and diagnosis in nursing process.

  • PDF

Empirical Study on Credit Spreads in Korea Corporate Market : Using Mean-Reverting Leverage Ratio Model (목표부채비율 회귀 모형을 이용한 한국채권시장의 신용가산금리에 대한 실증연구)

  • Kim, Jae-Woo;Kim, Hwa-Sung
    • The Korean Journal of Financial Management
    • /
    • v.22 no.1
    • /
    • pp.93-118
    • /
    • 2005
  • This paper examines credit spreads in Korea corporate market using one of structural models, the mean reverting leverage ratio model (Collin-Dufresne and Goldstein (2001)). Compared to the actual credit spreads, we show that the credit spreads induced by the model are overpredicted. We also investigate the systematic errors that cause the over-pre-diction of credit spreads using the t-test. We show that the systematic errors are affected by the current leverage ratio and asset volatility.

  • PDF

Progress of Rice Injury Caused by the First Generation of Striped Rice Borer(Chilo suppressalis(Walker)) (Lepidoptera: pyralidae) (제1화기(第1化期) 이화명나방(Chilo suppressalis (Walker))에 의(依)한 수도피해(水稻被害) 진전양상(進展樣相))

  • Ryoo, Mun-Il;Lee, Moon-Hong
    • Korean journal of applied entomology
    • /
    • v.25 no.1 s.66
    • /
    • pp.17-20
    • /
    • 1986
  • Based on the data of rice injury caused by the first generation of striped rice borer(Chilo suppressalis (Walker)), which were collected in the three years from 1974 to 1976 in Sweon area, progress of the injury in relation to Degree Days was studied. Increase in the number of infested stems was strongly related to the dispersal features of larvae. The increase ceased at about 400 DD after modal emergence date when the larval distribution pattern became stable. The regression of the number of infested stems per infested hill on Degree Days was significant and the coefficients of determaination were 0.84 and 0.95 for 1974 and 1976, respectively. The regression coefficients in the two years were not statistically significant, suggesting a possibility for pre- diction of the mean number of infested stems per infested hill through a simple model.

  • PDF

Estimating Carrying Capacity of Lake Shihwa for Water Quality Management (수질관리를 위한 시화호의 환경용량 산정)

  • Kim, Hyung-Chul;Choi, Woo-Jeung;Lee, Won-Chan;Koo, Jun-Ho;Lee, Pil-Yong;Park, Sung-Eun;Hong, Seok-Jin;Jang, Ju-Hyoung
    • Journal of Environmental Science International
    • /
    • v.16 no.5
    • /
    • pp.571-581
    • /
    • 2007
  • The mechanism of water pollution in Lake Shihwa, one of highly eutrophicated artificial lakes in Korea, has been studied using a numerical 3D physical-biochemical coupled model. In this study, the model was applied to estimate the contribution of land-based pollutant load to water quality of heavily polluted Lake Shihwa. The chemical oxygen demand(COD) was adopted as an index of the lake water quality, and the spatial distribution of an average COD concentration during the summer from 1999 to 2000 was simulated by the model. The simulated COD showed a good agreement with the observed data. According to reproducibility of COD, the high-est levels between 8 and 9 mg/L were shown at the inner site of the lake with inflow of many rivers and ditches, while the lowest was found to be about 5 mg/L at the southwestern site near to dike gate. In the pre-diction of water quality of Lake Shihwa, COD showed still higher levels than 3 mg/L in case of reduction of 95% for land-based pollutant load. This suggests that the curtailment of land-based pollutant load is not only sufficient but the improvement of sediment quality or the increase of seawater exchange should be considered together to improve a water quality in Lake Shihwa.