• 한국산학기술학회논문지
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• 제17권6호
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• pp.389-399
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• 2016

본 연구의 목적은 최근 10년간(2005-2014) 만성 요통을 가진 중년 여성을 대상으로 국내에서 실시된 운동중재 연구의 현황을 파악하고, 운동 중재 연구의 효과를 알아보기 위해 시도된 것이다. 문헌검색은 한국교육학술정보원(http://www.riss.kr), 국회도서관, 한국학술정보(http://kiss.kstudy.com)와 DBpia(http://www.dbpia.co.kr)를 통해 검색하였다. PRISMA(preferred reporting items for systematic reviews and meta-analysis, 2008) 가이드라인에 따라 자료를 수집한 후 연구자가 원본을 확인하고, 선별하여 총 12편의 논문을 최종 분석하였다. 분석한 논문 중 간호학 전공 논문은 1편이었으며, 11편은 타과 논문이었다. Scottish Intercollegiate Guideline Network의 체크리스트를 참고하여 논문의 질적 평가를 실시하였다. 논문의 질적 평가내용을 종합한 결과, 10점 만점에 8점인 연구가 1편이었으며, 5-6점인 연구는 8편 이었고, 3-4점인 연구가 3편이었다. 운동 중재내용을 분석한 결과 평균 55분을 시행하였으며, 1주일에 평균 3.1회의 빈도로 총 시행횟수는 평균 29.7회로 진행되었다. 연구 결과 요부신경근 조절운동, 요가운동, 수중운동이 중년여성의 요통에 효과가 있는 것으로 나타났으며, 향후 이를 간호학 중재로 활용하여 근거기반 간호실무의 토대를 마련할 수 있을 것이다.

• 벤처창업연구
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• 제15권1호
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• pp.269-284
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• 2020

본 연구는 한국의 바이오메디컬 산업을 중심으로 창업가의 배태조직과 창업경험이 형성하는 창업기업의 핵심경영자원을 탐색적으로 살펴보았다. 이를 위해 바이오메디컬 분야의 창업가 13인을 대상으로 심층 인터뷰를 수행하였다. 선행연구를 바탕으로 창업기업의 핵심 경영자원을 크게 기술 역량, 조직관리 역량, 네트워크 역량, 시장개척 역량 등 4가지로 분류하고 이를 중심으로 반구조화된 질문지를 구성하였다. 인터뷰 내용을 정리한 결과, 창업가의 배태조직 및 창업경험이 형성하는 창업기업의 핵심경영자원을 18가지 세부요인으로 구분할 수 있었다. 특히 기존의 실증연구들이 잘 다루지 않던 요인들을 발견할 수 있었는데, 기술 역량을 구성하는 요인들 중'기술개발 자신감'과 'R&D 수행방식', 조직관리 역량을 구성하는 요인들 중'조직문화', 네트워크 역량을 구성하는 요인들 중 '정신적 지원', 시장개척 역량을 구성하는 요인들 중 '시행착오를 통한 학습'과 '명성자원' 등이 이에 해당한다. 본 연구는 창업가의 배태조직 및 창업경험의 역할을 다룬 질적 연구로서 희소성이 있을 뿐 아니라 이 경험들이 형성하는 기업의 핵심경영자원을 4가지로 유형화하고 있어 향후 연구에서 유용하게 활용될 것으로 기대된다.

• Nutrition Research and Practice
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• 제17권4호
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• pp.682-697
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• 2023

BACKGROUND/OBJECTIVES: Tibetan tea is a kind of dark tea, due to the inherent complexity of natural products, the chemical composition and beneficial effects of Tibetan tea are not fully understood. The objective of this study was to unravel the composition of Tibetan tea using knowledge-guided multilayer network (KGMN) techniques and explore its potential antioxidant and hypolipidemic mechanisms in mice. MATERIALS/METHODS: The C57BL/6J mice were continuously gavaged with Tibetan tea extract (T group), green tea extract (G group) and ddH2O (H group) for 15 days. The activity of total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) in mice was detected. Transcriptome sequencing technology was used to investigate the molecular mechanisms underlying the antioxidant and lipid-lowering effects of Tibetan tea in mice. Furthermore, the expression levels of liver antioxidant and lipid metabolism related genes in various groups were detected by the real-time quantitative polymerase chain reaction (qPCR) method. RESULTS: The results showed that a total of 42 flavonoids are provisionally annotated in Tibetan tea using KGMN strategies. Tibetan tea significantly reduced body weight gain and increased T-AOC and SOD activities in mice compared with the H group. Based on the results of transcriptome and qPCR, it was confirmed that Tibetan tea could play a key role in antioxidant and lipid lowering by regulating oxidative stress and lipid metabolism related pathways such as insulin resistance, P53 signaling pathway, insulin signaling pathway, fatty acid elongation and fatty acid metabolism. CONCLUSIONS: This study was the first to use computational tools to deeply explore the composition of Tibetan tea and revealed its potential antioxidant and hypolipidemic mechanisms, and it provides new insights into the composition and bioactivity of Tibetan tea.

• Asia pacific journal of information systems
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• 제22권3호
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• pp.53-74
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• 2012

A challenge in fostering virtual communities is the continuous supply of knowledge, namely members' willingness to contribute knowledge to their communities. Previous research argues that giving away knowledge eventually causes the possessors of that knowledge to lose their unique value to others, benefiting all except the contributor. Furthermore, communication within virtual communities involves a large number of participants with different social backgrounds and perspectives. The establishment of mutual understanding to comprehend conversations and foster knowledge contribution in virtual communities is inevitably more difficult than face-to-face communication in a small group. In spite of these arguments, evidence suggests that individuals in virtual communities do engage in social behaviors such as knowledge contribution. It is important to understand why individuals provide their valuable knowledge to other community members without a guarantee of returns. In virtual communities, knowledge is inherently rooted in individual members' experiences and expertise. This personal nature of knowledge requires social interactions between virtual community members for knowledge transfer. This study employs the social capital theory in order to account for interpersonal relationship factors and identity theory for individual and group factors that may affect knowledge contribution. First, social capital is the relationship capital which is embedded within the relationships among the participants in a network and available for use when it is needed. Social capital is a productive resource, facilitating individuals' actions for attainment. Nahapiet and Ghoshal (1997) identify three dimensions of social capital and explain theoretically how these dimensions affect the exchange of knowledge. Thus, social capital would be relevant to knowledge contribution in virtual communities. Second, existing research has addressed the importance of identity in facilitating knowledge contribution in a virtual context. Identity in virtual communities has been described as playing a vital role in the establishment of personal reputations and in the recognition of others. For instance, reputation systems that rate participants in terms of the quality of their contributions provide a readily available inventory of experts to knowledge seekers. Despite the growing interest in identities, however, there is little empirical research about how identities in the communities influence knowledge contribution. Therefore, the goal of this study is to better understand knowledge contribution by examining the roles of social capital and identity in virtual communities. Based on a theoretical framework of social capital and identity theory, we develop and test a theoretical model and evaluate our hypotheses. Specifically, we propose three variables such as cohesiveness, reciprocity, and commitment, referring to the social capital theory, as antecedents of knowledge contribution in virtual communities. We further posit that members with a strong identity (self-presentation and group identification) contribute more knowledge to virtual communities. We conducted a field study in order to validate our research model. We collected data from 192 members of virtual communities and used the PLS method to analyse the data. The tests of the measurement model confirm that our data set has appropriate discriminant and convergent validity. The results of testing the structural model show that cohesion, reciprocity, and self-presentation significantly influence knowledge contribution, while commitment and group identification do not significantly influence knowledge contribution. Our findings on cohesion and reciprocity are consistent with the previous literature. Contrary to our expectations, commitment did not significantly affect knowledge contribution in virtual communities. This result may be due to the fact that knowledge contribution was voluntary in the virtual communities in our sample. Another plausible explanation for this result may be the self-selection bias for the survey respondents, who are more likely to contribute their knowledge to virtual communities. The relationship between self-presentation and knowledge contribution was found to be significant in virtual communities, supporting the results of prior literature. Group identification did not significantly affect knowledge contribution in this study, inconsistent with the wealth of research that identifies group identification as an important factor for knowledge sharing. This conflicting result calls for future research that examines the role of group identification in knowledge contribution in virtual communities. This study makes a contribution to theory development in the area of knowledge management in general and virtual communities in particular. For practice, the results of this study identify the circumstances under which individual factors would be effective for motivating knowledge contribution to virtual communities.

• 유통과학연구
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• 제10권6호
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• pp.39-53
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• 2012

기업에 경쟁우위를 가져다주는 많은 자원들 중에서 특히 지식(knowledge)은 생산 활동을 위해 다른 자원을 변화시키거나 확보할 수 있도록 만드는 중요한 자원으로 알려져 있다. 이러한 조직 내 지식은 다양한 형태로 존재하고, 다양한 장소나 개인에게 산재해 있기 때문에, 이를 통합하고 체계적으로 활용하기 위한 기업의 전사적 관리 활동이 필요하다. 특히 지식관리시스템(KMS: knowledge management systems)은 조직 내 지식을 창조하고, 공유하고, 적절히 사용함으로써 지식관리 프로세스를 지원하고 조직이 가진 지식자원의 가치를 극대화하여 기업의 학습조직화와 성과 증진을 이끌 수 있다. 이에 본 연구는 국내 대표적인 프랜차이즈 기업인 파리바게뜨의 성공적인 지식관리시스템운영 사례를 분석하여 프랜차이즈 기업들의 지식경영을 강화 및 지식관리시스템(KMS) 구축과 개선을 위한 구체적인 시사점을 제안하고자 하였다. 결과적으로 최고경영층의 관심과 지원, 능동적인 지식 공유와 활용을 위한 학습조직 문화, 네트워크 활성화를 통한 지식의 변환, 정보기술, 지식경영의 내재화를 위한 촉진제도와 보상이라는 5가지 주요 요인이 프랜차이즈 기업의 지식관리시스템의 성공적 운영을 위해 반드시 고려되어야 하는 요인임을 밝혀낼 수 있었다.