• Fisheries and Aquatic Sciences
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• v.26 no.5
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• pp.305-317
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• 2023

Ethiopia is branded as the Water Tower of Africa because of its abundant inland water bodies that may be used sustainably to boost the economy. This review article's goal is to examine the current status and future potential of Ethiopia's fisheries, with a special focus on reservoirs. There are 200 known fish species (194 native, 40 endemic, and 11 exotic) in in Ethiopia's inland water. Ethiopia's fish production has increased by a factor of more than five in the past three decades (3,500 tons in 1983 to 15,681 tons in 2000 and 18,058 tons in 2010). However, fish produced in reservoirs is too low (8,059 t/year). The current fish harvests from reservoirs are significantly below the predicted potential yield, accounting for only 35% of the calculated fish production capacity. In this review, 14 potential reserves were revealed. A total of 48 fish species have been reported in these, of which 26 species (or around 54%) are present in Alwero reservoir. 19 of the 48 species that have been officially recognized belong to the Cyprinidae family and made up nearly 40% of the fish population in Ethiopian reservoirs. There has been, however, a decline in the productivity of Ethiopia's reservoir fish. Hence, actively start fishing in the numerous reservoirs that have been neglected yet, link the potential of fisheries and the benefits of the fish farming supply chain, let's begin building several other reservoirs similar to the Grand Ethiopian Renaissance Dam and beginning mechanized-based fish harvesting.

• Advances in concrete construction
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• v.2 no.3
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• pp.163-176
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• 2014

Essentially, when electrical current flows easily in concrete that has large pores filled with highly connective pore water, this is an indication of a low resistivity concrete. In concrete, the flow of current between anodic and cathodic sites on a steel reinforcing bar surface is regulated by the concrete electrical resistance. Therefore, deterioration of any existing reinforced concrete structure due to corrosion of reinforcement steel bar is governed, to some extent, by resistivity of concrete. Resistivity of concrete can be improved by using SCMs and thus increases the concrete electrical resistance and the ability of concrete to resist chloride ingress and/or oxygen penetration resulting in prolonging the onset of corrosion. After depassivation it may slow down the corrosion rate of the steel bar. This indicates the need for further study of the effect of electric arc furnace dust (EAFD) addition on the concrete resistivity. In this study, concrete specimens rather than mortars were cast with different additions of EAFD to verify the electrochemical results obtained and to try to understand the role of EAFD addition in influencing the corrosion behaviour of reinforcing steel bar embedded in concrete and its relation to the resistivity of concrete. The results of these investigations indicated that the corrosion resistance of steel bars embedded in concrete containing EAFD was improved, which may link to the high resistivity found in EAFD-concrete. In this paper, potential measurements, corrosion rates, gravimetric corrosion weight results and resistivity measurements will be presented and their relationships will also be discussed in details.

• Journal of the Korean Society of Physical Medicine
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• v.13 no.3
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• pp.141-150
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• 2018

PURPOSE: This study was conducted to understand the adaptive responses of different modes of physical exercises utilizing skeletal muscle and the comprehensive relevance of AMPK signaling that can be activated by physical exercise as a potential molecular target in human health problems such as neuromuscular disorders (NMDs). METHODS: Most of the contents in this review article are based on recent publications concerning the main topics of interest. The reference literatures cited were obtained by basic searches of overseas academic databases such as PubMed and ScienceDirect using EndNote X7.8. RESULTS: The phenotypic adaptive responses of skeletal muscle during endurance- and resistance-based exercise training (ET and RT respectively) appear to be distinct. To explain the adaptive responses in each single mode of exercises (ET, RT) along with combined exercise training (CT), AMPK signaling is proposed as an important molecular link among those differential modes of exercise and a promising molecular target of NMDs. CONCLUSION: Based on the available evidence, intracellular AMPK signaling activated by diverse stimuli including physical exercise can be a potential and promising therapeutic target for the prevention, amelioration or cure of various human health problems including NMDs and may also be beneficial for physical rehabilitation and emergency situations that may elicit acute metabolic stresses.

• The Korean Journal of Physiology and Pharmacology
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• v.7 no.2
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• pp.103-109
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• 2003

The cellular mechanisms that contribute to the acceleration of atherosclerosis in diabetes are poorly understood. Therefore, the potential mechanisms involved in the diabetes-dependent increase in vascular smooth muscle cell (VSMC) proliferation was investigated. Using primary culture of VSMC from streptozotocin-induced diabetic rat aorta, cell proliferation assay showed two-fold increase in cell number accompanied with enhanced superoxide generation compared to normal VSMC, 2 days after plating. Both the increased superoxide production and cell proliferation in diabetic VSMC were significantly attenuated by not only tiron (1 mM), a superoxide scavenger, but also by diphenyleneiodonium (DPI; $10{\mu}M$), an NAD(P)H oxidase inhibitor. NAD(P)H oxidase activity in diabetic VSMC was significantly higher than that in control cell, accompanied with increased mRNA expression of p22phox, a membrane subunit of oxidase. Furthermore, inhibition of p22phox expression by transfection of antisense p22phox oligonucleotides into diabetic VSMC resulted in a decrease in superoxide production, which was accompanied by a significant inhibition of cell proliferation. Based on these results, it is suggested that diabetes-associated increase in NAD(P)H oxidase activity via enhanced expression of p22phox contributes to augmented VSMC proliferation in diabetic rats.

• Toxicological Research
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• v.26 no.1
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• pp.1-8
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• 2010

The process of new drug development consists of several stages; after identifying potential candidate compounds, preclinical studies using animal models link the laboratory and human clinical trials. Among many steps in preclinical studies, toxicology and safety assessments contribute to identify potential adverse events and provide rationale for setting the initial doses in clinical trials. Gene modulation is one of the important tools of modern biology, and is commonly employed to examine the function of genes of interest. Advances in new drug development have been achieved by exploding information on target selection and validation using genetically modified animal models as well as those of cells. In this review, a recent trend of genetically modified methods is discussed with reference to safety assessments, and the exemplary applications of gene-modulating tools to the tests in new drug development were summarized.

• Korean Journal of Organic Agriculture
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• v.12 no.2
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• pp.121-134
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• 2004

Crop inputs in excess of the yield potential of the soil type reduce profitability and increase pollution problems from leaching and runoff. Inaccurate fertilizer and pesticide application can also result in profit loss. Current farming practices plan only for the dominate soil in the field. A government-supported program titled "Pilot village project for the environment-friendly agriculture" was proceeded from 1999 to 2001 to tackle the problems with which our agriculture is faced by introducing IPM, INM and others. The objective of this study is to consider the potential input savings of agricultural chemicals and economic feasibility of the project compared with the conventional farming. The results of the analysis indicate the followings: (1) organic or no-pesticide farming size was increased from 9% in 1999 to 20% in 2001 ; (2) crop yield was a link bit lower than that of the conventional farming, but the sal6 price, gross income and income of the pilot village were 6%, 10% and 9% higher than that of the conventional farming, respectively; and (3) fertilizer and pesticide use also showed decreasing trend gradually.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2008.04a
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• pp.89-99
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• 2008

GPCRs are large families of cell surface receptors that transmit signals through conformational changes upon ligand activation and an interaction with the heterotrimeric G-proteins. GPCRs regulate the cell-signaling pathways and participate in the regulation of physiological processes through the G-proteins defined by their ${\alpha}$ subunits. A family of 20 G protein-coupled receptors (GPCRs) that provide a large class of tractable drug targets for new anti-inflammatory drugs and, in certain instances, for the treatment of the inflammatory indications such as atherosclerosis, rhinitis, asthma, pulmonary disease and arthritis. In view of the important findings showing that $G{\alpha}_{12}/G{\alpha}_{13}$ regulate the various cellular processes such as actin-stress fiber formation, neurite retraction, platelet aggregation, gene induction, and apoptosis, we became interested in whether, after coupling to the activated GPCRs, the G-proteins and their downstream molecules might be involved in the pathologic processes of chronic inflammatory diseases (e.g., liver fibrosis). In this symposium, the possible link of the G-proteins with the pathophysiology will be discussed with the aim of finding potential new drug targets.

• Journal of Korean Foot and Ankle Society
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• v.27 no.3
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• pp.103-107
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• 2023

Quinolone antibiotics are frequently prescribed for suspected respiratory or urinary tract infections because of their effectiveness and generally perceived safety profile. On the other hand, some studies have raised concerns regarding the potential association between quinolone use and Achilles tendinopathy or tendon rupture. There is a lack of reports on the link between quinolone use and multiple tendon and tendon attachment site pain in the foot and ankle joints; hence, this study examined this issue further. This paper presents a case report of a patient with persistent Achilles tendinopathy and multiple tendon and tendon attachment site pain in the foot who did not respond adequately to conservative treatments. In particular, the discontinuation of quinolone use resulted in favorable clinical outcomes. This report offers valuable insights into the potential risks associated with quinolone antibiotics and highlights the importance of vigilance when managing patients with tendon-related complaints. A comprehensive review of the relevant literature is also presented to contextualize these findings.

• 대한공업교육학회지
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• v.33 no.2
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• pp.72-96
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• 2008

This study was done through survey of the school and the small and medium enterprise which participated in "Human resources development program of small and medium enterprise technical high school's customized link", and we researched the problem with the actual condition of the program operation and analyzed the results of them. The analysis results are as follows. Firstly, the teachers recognized the purpose of this program operation as the activation of the occupation education between school and job world, On the other hand, people in charge of the company recognized the purpose of this program operation as the professional human resources supply to the small and medium enterprises. Secondly, the teachers perceived that the students' performative competence had improved through the operation of this program, while the inducement of some excellent students was not always available. Finally people in charge of the company responded that this program was helpful for the manpower guarantee, the profits of the company, the enhancement of the performative competence and adaptability of the high school graduates, and the cooperation of the technical high school and the company. However, they admitted that this program lacked the maintenance and repairing competence of the utilities, ability of grasping problems and the problem-solving skills, and the competence of the functional expertise of the high school graduates. Generally, the teachers of technical high school and people in charge of the company which participate in "Human resources program of small and medium enterprise technical high school's customized link" expressed positive appreciation for efficient management and potential development of this program.

• Management & Information Systems Review
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• v.30 no.4
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• pp.315-338
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• 2011

A "high-potential employee" is an employee who has been identified as having the potential, ability and aspiration for successive leadership positions within the company and identify employees who have the greatest future potential and make them future-ready to take your organization to success. The primary purpose of this paper is to investigate the relationships of corporate performance on the high potential employee system using the samples from HCCP panel data. This study seeks to identify a significant high potential employee system though empirical research as well. Results of empirical study are summarized. Finally suggestions, implications and limitations of the present study are also discussed. In this article, we explore the role of competitive strategy and technological environment in the introduction of high-potential employees and its link to impact of these performance.