• Proceedings of the KIPE Conference
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• 2001.07a
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• pp.475-478
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• 2001

In performing the three-level SVPWM, it is nearly impossible to control the neutral-point potential exactly to the half of the dc-link voltage at all times. Therefore the inverter would produce an erroneous output voltage by this voltage unbalance. So the voltage unbalance has to be compensated in doing PWM, when the voltage unbalance occurs whether it is small or large, to make the inverter output voltage follow the reference voltage exactly the same. In this paper, a new compensating method for the neutral-point potential variation in a three-level inverter space vector PWM (SVPWM) is presented. By using the proposed method, the output voltage of the inverter can be made same as the reference voltage and thus the current and torque ripple of the inverter driven motor can be greatly improved even if the voltage unbalance is quite large. The proposed method is verified experimentally with a 3-level IGBT inverter.

• Journal of Microbiology and Biotechnology
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• v.34 no.9
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• pp.1739-1747
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• 2024

Alzheimer's disease (AD) is a progressive neurological disorder that represents a major cause of dementia worldwide. Its pathogenesis involves multiple pathways, including the amyloid cascade, tau protein, oxidative stress, and metal ion dysregulation. Recent studies have suggested a critical link between changes in gut microbial diversity and the disruption of the gut-brain axis in AD. Previous studies primarily explored the potential benefits of probiotics and prebiotics in managing AD. However, studies have yet to fully describe a novel promising approach involving the use of synbiotics, which include a combination of active probiotics and new-generation prebiotics. Synbiotics show potential for mitigating the onset and progression of AD, thereby offering a holistic approach to address the multifaceted nature of AD. This review article primarily aims to gain further insights into the mechanisms of AD, specifically the intricate interaction between gut bacteria and the brain via the gut-brain axis. By understanding this relationship, we can identify potential targets for intervention and therapeutic strategies to combat AD effectively. This review also discusses substantial evidence supporting the role of synbiotics as a promising AD treatment that surpasses traditional probiotic or prebiotic interventions. We find that synbiotics may be used not only to address cognitive decline but also to reduce AD-related psychological burden, thus enhancing the overall quality of life of patients with AD.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.6
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• pp.2546-2566
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• 2016

This paper investigates an efficient transmission scheme for the remote wireless sensors to receive information which is rarely discussed in the integrated remote wireless sensor and multibeam satellite networks (IWSMSNs). The networks can be employed to exchange sensing information for emergency scenario, ocean scenario, and so on, which are isolated from available terrestrial networks. As the efficient transmission link is important to the IWSMSNs, we propose a hybrid full frequency (HFF) precoding by taking advantage of frequency reuse and multiple-input multiple-output (MIMO) precoding. Considering energy efficiency and sinks fairness are crucial to transmission link, thus the HFF precoding problems are formulated as transmit power minimization (TPM) and max-min fair (MMF) received signal to interference plus noise ratio (SINR) problems, which can be transformed to indefinite quadratic optimization programs. Then this paper presents a semi-definite programming (SDP) algorithm to solve the problems for the IWSMSNs. The promising potential of HFF for the real IWSMSNs is demonstrated through simulations.

• Molecules and Cells
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• v.40 no.11
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• pp.855-863
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• 2017

Adipose tissue plays a central role in regulating dynamic cross-talk between tissues and organs. A detailed description of molecules that are differentially expressed upon changes in adipose tissue mass is expected to increase our understanding of the molecular mechanisms that underlie obesity and related metabolic co-morbidities. Our previous studies suggest a possible link between endophilins (SH3Grb2 proteins) and changes in body weight. To explore this further, we sought to assess the distribution of endophilin A2 (EA2) in human adipose tissue and experimental animals. Human paired adipose tissue samples (subcutaneous and visceral) were collected from subjects undergoing elective abdominal surgery and abdominal liposuction. We observed elevated EA2 gene expression in the subcutaneous compared to that in the visceral human adipose tissue. EA2 gene expression negatively correlated with adiponectin and chemerin in visceral adipose tissue, and positively correlated with $TNF-{\alpha}$ in subcutaneous adipose tissue. EA2 gene expression was significantly downregulated during differentiation of preadipocytes in vitro. In conclusion, this study provides a description of EA2 distribution and emphasizes a need to study the roles of this protein during the progression of obesity.

• Korean Journal of Optics and Photonics
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• v.12 no.1
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• pp.32-39
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• 2001

We analyze the effectiveness of the PMD compensation as a function of the link PDL, to acquire the guidelines for the successful deployment of PMDC. Result shows that the amount of BER improvement from the PMDC is decreased as the link PDL increases. Because PDL elements in the transmission system make well-defined two PSPs under the absence of PDL not orthogonal anymore, and proper definition of fast and slow polarization harder. Accordingly, consideration of PDL's potential effects must be needed for design of polarization mode dispersion compensation.sation.

• Food Science of Animal Resources
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• v.31 no.2
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• pp.147-157
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• 2011

Mycobacterium avium paratuberculosis (MAP), the cause of Johne's disease in animals, may be a causative agent of Crohn's disease (CD) in humans, but the evidence supporting this claim is controversial. Milk, meat, and water could be potential sources of MAP transmission to humans. Thus, if the link between MAP and Crohn's disease is substantiated, the fact that MAP has been detected in retail foods could be a public health concern. The purpose of the present study was to review the link between MAP and CD, the prevalence of MAP in foods, heat inactivation, control of MAP during food processing, and detection methods for MAP. Although MAP positive rates in retail milk in nine countries ranged from 0 to 2.9% by the culture method and from 4.5 to 15.5% by PCR, high temperature short time pasteurization can effectively control MAP. The effectiveness of pasteurization to inactivate MAP depends on the initial concentration of the MAP in raw milk. Development of highly sensitive and specific rapid detection methods for MAP may enhance investigation into the relationship between MAP and CD, the prevention of the spread of MAP, and problem-solving related to food safety. Collaboration and efforts by government agencies, the dairy industry, farmers, veterinarians, and scientists will be required to reduce and prevent MAP in food.

• Journal of Electrical Engineering and Technology
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• v.8 no.4
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• pp.808-812
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• 2013

Multilayer capacitors with high ripple current and high capacitance were manufactured. The electrical properties of these capacitors were characterized for potential application for DC-link capacitors in hybrid electric vehicle inverters. Internal electrode structures were designed to achieve high capacitance and reliability. A single multilayer capacitor showed $0.46{\mu}F/cm^3$ of capacitance, 0.65% of dielectric loss, and 1450 V to 1650 V of dielectric breakdown voltage depending on the design of the internal electrode. The capacitor module designed with several multilayer capacitors gave a total capacitance of $450{\mu}F$, which is enough for hybrid electric vehicles. In particular, an equivalent series resistance of $4.5m{\Omega}$ or less will result in 60 $A_{rms}$, thereby reaching the allowed ripple current for hybrid electric vehicles.

• Journal of Electrical Engineering and Technology
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• v.11 no.4
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• pp.905-914
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• 2016

This paper proposes a new phase current reconstruction technique for interleaved three-phase bidirectional dc-dc converters using a single current sensor. In the proposed current reconstruction algorithm, a single current sensor is employed at the dc-link, and the dc-link current information is sampled at either the peak or valley point of the pulse-width modulation (PWM) carriers regularly. From the obtained current information, all phase currents are reconstructed in a single PWM cycle. After that, the digital current controller is applied to achieve current balancing in each phase. Compare to the previous multiple current sensor method, the proposed strategy reduces the number of the current sensors in the interleaved three-phase bidirectional converter as well as reducing potential current sensing error caused by non-ideal characteristics of the multiple current sensors. The effectiveness of the proposed method is verified from the experiments based on a 3kW three-phase bidirectional converter prototype for the automotive battery charging application.

• Journal of Preventive Medicine and Public Health
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• v.55 no.4
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• pp.398-406
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• 2022

Objectives: While the risk of depression is expected to substantially increase among older adults receiving community care, leisure life satisfaction can be regarded as a key component in enhancing the mental health of those receiving community care. However, it is not yet known whether community care utilization increases the risk of depression, or what role is played by leisure life satisfaction in these settings. This study investigated the relationship between community care utilization and depression, as well as the main effect and the moderating role of leisure life satisfaction on the link between community care utilization and depression among older adults. Methods: This study, using the 2019 Korean Welfare Panel Survey, conducted multiple regression analysis on data from 4494 elderly people aged 65 years or older. Results: After controlling for potential covariates, older community care recipients were more likely to report symptoms of depression than those who did not receive community care. Meanwhile, leisure life satisfaction was negatively associated with depression in older adults. The test for interaction between community care utilization and leisure life satisfaction revealed that leisure life satisfaction significantly attenuated the link between depression and community care utilization. Conclusions: The findings of this study imply that leisure life satisfaction could play a meaningful role in improving the mental health of older adults receiving community care. Welfare policies affecting older adults should consider leisure life satisfaction as an important resource for reducing depression in community care settings.

• Advances in aircraft and spacecraft science
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• v.2 no.1
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• pp.95-108
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• 2015

Automatic Dependent Surveillance Broadcast (ADS-B) is quickly being adopted by aviation safety authorities around the world as the standard for aircraft tracking. The technology provides the opportunity for live tracking of aircraft positions within range of an ADS-B receiver stations. Currently these receiver stations are bound by land and local infrastructural constraints. As such there is little to no coverage over oceans and poles, over which many commercial flights routinely travel. A low cost space based ADS-B receiving system is proposed as a constellation of small satellites. The possibility for a link between aircraft and satellite is dependent primarily on proximity. Calculating the likelihood of a link between two moving targets when considering with the non-periodic and non-uniform nature of actual aircraft flight-paths is non-trivial. This analysis of the link likelihood and the performance of the tracking ability of the satellite constellation has been carried out by a direct simulation of satellites and aircraft. Parameters defining the constellation (satellite numbers, orbit size and shape, orbit configuration) were varied between reasonable limits. The recent MH370 disappearance was simulated and potential tracking and coverage was analysed using an example constellation. The trend of more satellites at a higher altitude inclined at 60 degrees was found to be the optimal solution.