• The Journal of the Korea Contents Association
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• v.20 no.11
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• pp.354-367
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• 2020

This study is on the consideration of the scope of application of art therapy and fractal through the review of literature at home and abroad. The complex system is the opposite of the Euclidean system, a concept suitable for understanding the contemporaries with ambiguous boundaries and decentralized phenomena. The self-similarity and inventiveness of fractal, the geometry of nature, is used as fractal art in art as well as tree trunk, cloud and plant, especially in art therapy, fractal is considered to be available in the field of mandala and neuroscience. From brain-based research to mandala, exposure to natural patterns, clinical diagnosis through fractal analysis and software development, fractal has potential elements that can be developed in art therapy. Fractal, which is easy to link with computers due to its nature, is a necessary study at this point when non-face-to-face contact with the Corona virus is recommended. Currently, research on fractal art therapy is insufficient in Korea. Therefore, this research is intended to present as a basis for scientific and objective diagnostic tools and treatment at clinical sites using art therapy using fractal.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.31 no.1
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• pp.41-45
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• 2020

Objective: The objective of this study was to assess serum, hair, and urinary magnesium (Mg) levels in children with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and both ASD and ADHD to reveal potential interactive effects. Methods: A total of 148 boys aged 4-9 years old were enrolled in this study, including 44 children with ADHD, 40 pediatric patients with ASD, 32 patients with both ADHD and ASD, as well as 32 healthy neurotypical children. Hair, serum, and urinary Mg levels were assessed using inductively-coupled plasma mass spectrometry (ICP-MS). Laboratory quality control was performed using certified reference materials of human hair, plasma, and urine. Results: No significant group difference in serum Mg levels was observed. Mg content in hair was found to be reduced in children with ADHD and ADHD+ASD compared to that in healthy controls by 11% and 15%, respectively. Urinary Mg levels in children with ADHD+ASD exceeded the control, ADHD, and ASD values by 51, 76, and 65%, respectively. Factorial analysis revealed significant contribution of ADHD to hair and urinary Mg levels. Multiple regression analysis demonstrated that hair and urinary Mg levels were considered as significant predictors of neurodevelopmental disorder complexity. Conclusion: We propose that impaired Mg status may provide a link between ADHD and ASD.

• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.165-174
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• 2018

Glioblastoma multiforme is the most lethal malignant brain tumor. Despite many intensive studies, the prognosis of glioblastoma multiforme is currently very poor, with a median overall survival duration of 14 months and 2-year survival rates of less than 10%. Although viral infections have been emphasized as potential cofactors, their influences on pathways that support glioblastoma progression are not known. Some previous studies indicated that human Kaposi's sarcoma-associated herpesvirus (KSHV) was detected in healthy brains, and its microRNA was also detected in glioblastoma patients' plasma. However, a direct link between KSHV infection and glioblastoma is currently not known. In this study, we infected glioblastoma cells and glioma stem-like cells (GSCs) with KSHV to establish an in vitro cell model for KSHV-infected glioblastoma cells and glioma stem-like cells in order to identify virologic outcomes that overlap with markers of aggressive disease. Latently KSHV-infected glioblastoma cells and GSCs were successfully established. Additionally, using these cell models, we found that KSHV infection modulates the proliferation of glioma stem-like cells.

• Proceedings of the Korean Vacuum Society Conference
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• 2015.08a
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• pp.158-158
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• 2015

Myoblast are myogenic precursors that proliferate, activate, and differentiate on muscle injury to sustain the regenerative capacity of skeletal muscle; The neuronal isoform of nitric oxide synthase (nNOS, termed also NOS-I) is expressed in normal adult skeletal muscle, suggesting important functions for Nitric oxide (NO) in muscle biology1,2,3. However, the expression and subcellular localization of NO in muscle development and myoblast differentiation are largely unknown. In this study, we examined effects of the nitric oxide generated by a microwave plasma torch, on proliferation/differentiation of rat myoblastic L6 cells. Experimental data pertaining to nitric oxide production are presented in terms of the oxygen input in units of cubic centimetres per minute. The various levels of nitric oxide are observed depending on the flow rate of nitrogen gas, the ratio of oxygen gas, and the microwave power4. In order to evaluate the potential of nitric oxide as an activator of cell differentiation, we applied nitric oxide generated from the microwave plasma torch to L6 skeletal muscles. Differentiation of L6 cells into myotubes was significantly enhanced the differentiation after nitric oxide treatment. Nitric oxide treatment also increase the expression of myogenesis marker proteins and mRNA level, such as myogenin and myosin heavy chain (MHC), as well as cyclic guanosine monophosphate (cGMP), However during the myotube differentiation we found that NO activate oxidative stress signaling erks expression. Therefore, these results establish a role of NO and cGMP in regulating myoblast differentiation and elucidate their mechanism of action, providing a direct link with oxidative stress signalling, which is a key player in myogenesis. Based on these findings, nitric oxide generated by plasma can be used as a possible activator of cell differentiation and tissue regeneration.

• Journal of Korean Academy of Nursing
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• v.27 no.4
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• pp.880-891
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• 1997

The purpose of this study was (1)to undertake a survey to identify the profile of inactive nurses, who account for 42.2% of the 130,000 RN(Registered Nurses) in Korea, (2)to identify factors related to the inactivation of these nurses, (3)to identify reasons behind the high turnover rate of nurses, and (4)to delineate measures for inactive nurses to participate in professional nursing activities so as to upgrade the quality of the health care delivery system in Korea. For these purposes, this study surveyed existing literature on the turnover of nurses and, used the nominal group technique of action research, to collect ideas from hospital/nurse administrators, inactive nurses, nurses on the job, graduate students in nursing, part-time nurses, patients, and their families to formulate strategies to mobilize inactive nurses. The findings are as follows : Frist, institutional supports should be provided to mobilize inactive nurses. To be more specific : (1) A data-base needs be created at the Korean Nurses Association to link inactive nurses with jobs available. (2) Retraining programs need be established to equip inactive nurses for new jobs. (3) Comprehensive information related to employment needs should be made available. Second, a conducive environment needs to be created to draw in inactive nurses to the job market. To be more specific : (1) A system of part-time work needs to be introduced in hospitals. (2) Nurse-specialists need to be promoted. (3) Potential jobs need to be created. (4) Working environment and terms and conditions for nurses need to be improved. (5) Competent nurses need to be secured in the health care delivery system. To achieve the goals presented above, this paper presented 55 specific strategies that may help mitigate the turnover rate of nurses and, in turn, help make the Korean Nurses Association effective in implementing its policies.

• Journal of Environmental Impact Assessment
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• v.17 no.2
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• pp.133-141
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• 2008

The loss, alteration, and fragmentation of habitat have led to a reduction of biodiversity. The growing awareness of the negative effects of habitat fragmentation on natural systems has resulted in conservation strategy that is concerned with not only population and habitat level but also ecosystem and landscape level. Especially, ecological network to link core areas or major habitat patches is one of the most important issues. Recently, landscape connectivity is increasingly used in decision making for fragmented landscape management in order to conserve the biodiversity in the regional scale. The objective of this study was to find potential forest as a ecological corridor in Go-yang city, Gyung-gi province using cost-distance modelling method that can measure connectivity based on animal movement. 'Least cost-distance' modelling based on functional connectivity can be useful to establish ecological network and biodiversity conservation plan. This method calculates the distance modified with the cost to move between habitat patches based on detailed geographical information on the landscape as well as behavioural aspects of the animal movement. The least cost-distance models are based on two biologically assumptions: (1) dispersers have complete knowledge of their surroundings, and (2) they do select the least cost route from this information. As a result of this study, we can find wildlife moving route for biodiversity conservation. The result is very useful for long-term aspect of biodiversity conservation plan in regional scale, because this is reflection of geographical information and behavioural aspects of the animal movement.

• The Journal of the Korea Contents Association
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• v.17 no.6
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• pp.39-54
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• 2017

This study started from the consciousness that the community media practice studies have been confined to the traditional terrestrial broadcasting. The following research results and implications were obtained by analyzing Daedeok-valley Radio's case to elucidate characteristics of online-based community media and content production and distribution characteristics neglected in previous researches. First, online community media activities are civic/citizen media activities that capture the value of local communities, and this locality is realized through media content production and its online distribution. Second, contents of online community media link members of the community, and individuals become nodes, interacting both online and offline. Therefore, online-based citizen media activities can be utilized effectively as a means to enhance civic participation and to achieve the locality of community in online and offline spaces depending on strategies for online contents production and distribution. Utilizing online infrastructures for media content creation and distribution in Korea demonstrates potential opportunities of local online media to be considered as niche media that can increase its own sustainability.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.4
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• pp.299-307
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• 2009

Emerging fiber optic sensor technologies have shown great potential to overcome the difficulties associated with conventional sensors. Fiber optic sensors are immune to EM noise and electric shock and thus can be used in explosion-prone areas. Several kinds of fiber optic sensors have been developed over the last two decades to take advantage of these merits. There have also been many field applications of fiber optic sensors for structural health monitoring as NDT/HDE. However, very few sensors, particularly a load cell have been successfully commercialized. This Paper Presents a load cell using fiber Bra99 gra1ing (FBG) sensors. The shape of the load cell is a link type, and three FBG sensors are used for measuring strains at three different points. Especially, these strains are processed with a differential method in order to exclude common mode noise such as temperature. Moreover, the sensitivity, the linearity and the resolution of the load cell were successfully verified from the experiment of tension test.

• Computers and Concrete
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• v.15 no.5
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• pp.771-794
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• 2015

This paper proposes an innovative method for selection of measurement sets in static parameter identification of concrete or steel bridges. This method is proved as a systematic tool to address the first steps of Structural System Identification procedures by observability techniques: the selection of adequate measurement sets. The observability trees show graphically how the unknown estimates are successively calculated throughout the recursive process of the observability analysis. The observability trees can be proved as an intuitive and powerful tool for measurement selection in beam bridges that can also be applied in complex structures, such as cable-stayed bridges. Nevertheless, in these structures, the strong link among structural parameters advises to assume a set of simplifications to increase the tree intuitiveness. In addition, a set of guidelines are provided to facilitate the representation of the observability trees in this kind of structures. These guidelines are applied in bridges of growing complexity to explain how the characteristics of the geometry of the structure (e.g. deck inclination, type of pylon-deck connection, or the existence of stay cables) affect the observability trees. The importance of the observability trees is justified by a statistical analysis of measurement sets randomly selected. This study shows that, in the analyzed structure, the probability of selecting an adequate measurement set with a minimum number of measurements at random is practically negligible. Furthermore, even bigger measurement sets might not provide adequate SSI of the unknown parameters. Finally, to show the potential of the observability trees, a large-scale concrete cable-stayed bridge is also analyzed. The comparison with the number of measurements required in the literature shows again the advantages of using the proposed method.

• The Korean Journal of Applied Statistics
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• v.22 no.6
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• pp.1215-1227
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• 2009

Underwriting refers to the process that the insurance company measures the potential risk of the future clients and decide whether insuring them with current premium. Although the traditional underwriting system used in Korean automobile insurance market is easy to understand, it is not based on a reliable statistical procedure. In this paper, we propose to apply the generalized additive model into construction of underwriting system, which is based on statistical analysis. We use automobile insurance data in Korea and apply our approach to the data. The results from the empirical analysis would be useful even for determining the significance of each variable in calculating automobile insurance premium.