• Title/Summary/Keyword: potential link

Search Result 290, Processing Time 0.032 seconds

Integrative understanding of immune-metabolic interaction

  • Im, Seonyoung;Kim, Hawon;Jeong, Myunghyun;Yang, Hyeon;Hong, Jun Young
    • BMB Reports
    • /
    • v.55 no.6
    • /
    • pp.259-266
    • /
    • 2022
  • Recent studies have revealed that the immune system plays a critical role in various physiological processes beyond its classical pathogen control activity. Even under a sterile condition, various cells and tissues can utilize the immune system to meet a specific demand for proper physiological functions. Particularly, a strong link between immunity and metabolism has been identified. Studies have identified the reciprocal regulation between these two systems. For example, immune signals can regulate metabolism, and metabolism (cellular or systemic) can regulate immunity. In this review, we will summarize recent findings on this reciprocal regulation between immunity and metabolism, and discuss potential biological rules behind this interaction with integrative perspectives.

Does IFITM3 link inflammation to tumorigenesis?

  • Jaewoong, Lee
    • BMB Reports
    • /
    • v.55 no.12
    • /
    • pp.602-608
    • /
    • 2022
  • Uncontrolled chronic inflammation, in most cases due to excessive cytokine signaling through their receptors, is known to contribute to the development of tumorigenesis. Recently, it has been reported that the antiviral membrane protein interferon-induced transmembrane protein 3 (IFITM3), induced by interferon signaling as part of the inflammatory response after viral infection, contributes to the development of B-cell malignancy. The unexpected oncogenic signaling of IFITM3 upon malignant B cell activation elucidated the mechanism by which the uncontrolled expression of inflammatory proteins contributes to leukemogenesis. In this review, the potential effects of inflammatory cytokines on upregulation of IFITM3 and its contribution to tumorigenesis are discussed.

Controlled Bandwidth Borrowing with Extended RSVP-TE to Maximize Bandwidth Utilization

  • Kim Chul;Kim Young-Tak
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.29 no.1B
    • /
    • pp.64-72
    • /
    • 2004
  • Multiprotocol Label Switching (MPLS) has been developed as a key technology to enhance the reliability, manageability and overall quality of service of core If networks with connection-oriented tunnel LSP and traffic engineering such as constraint-based routing, explicit routing, and restoration. In this paper, we propose a control bandwidth borrowing scheme that maximizes the utilization of tunnel LSPs or physical links by an extension to the RSVP-TE label distribution protocol. MPLS-based core switching network and VPN services rely on the establishment of connection-oriented tunneled LSPs that are configured or predefined by network management systems. The mechanism of network management system varies from (i) a relatively static LSP establishment accounting, to (ii) a dynamic QoS routing mechanisms. With the use of hierarchical LSPs, the extra bandwidth that is unused by the trunk (outer) LSPs should be fully allocated to their constituent end-to-end user traffic (inner) LSPs in order to maximize their utilization. In order to find out the unused extra bandwidth in tunnel LSP or physical link and redistribute these resources to constituent LSPs, we expend the functionality of RSVP-TE and the found unused extra bandwidth is redistributed with a weight-based recursive redistribution scheme. By the extended RSVP-TE and proposed recursive redistributed scheme, we could achieve the instantaneous maximized utilization of tunnel LSP or physical link suffering from the potential under-utilization problem and guarantee the end-to-end QoS requirements. With the proposed scheme, network manager can manage more effectively the extra available bandwidth of hierarchical LSPs and maximize the instantaneous utilization of the tunneled LSP resources.

Molecular Analysis of Archaea, Bacteria and Eucarya Communities in the Rumen - Review-

  • White, B.A.;Cann, I.K.O.;Kocherginskaya, S.A.;Aminov, R.I.;Thill, L.A.;Mackie, R.I.;Onodera, R.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.12 no.1
    • /
    • pp.129-138
    • /
    • 1999
  • If rumen bacteria can be manipulated to utilize nutrients (i.e., ammonia and plant cell wall carbohydrates) more completely and efficiently, the need for protein supplementation can be reduced or eliminated and the digestion of fiber in forage or agricultural residue-based diets could be enhanced. However, these approaches require a complete and accurate description of the rumen community, as well as methods for the rapid and accurate detection of microbial density, diversity, phylogeny, and gene expression. Molecular ecology techniques based on small subunit (SSU) rRNA sequences, nucleic acid probes and the polymerase chain reaction (PCR) can potentially provide a complete description of the microbial ecology of the rumen of ruminant animals. The development of these molecular tools will result in greater insights into community structure and activity of gut microbial ecosystems in relation to functional interactions between different bacteria, spatial and temporal relationships between different microorganisms and between microorganisms and reed panicles. Molecular approaches based on SSU rRNA serve to evaluate the presence of specific sequences in the community and provide a link between knowledge obtained from pure cultures and the microbial populations they represent in the rumen. The successful development and application of these methods promises to provide opportunities to link distribution and identity of gastrointestinal microbes in their natural environment with their genetic potential and in situ activities. The use of approaches for assessing pupulation dynamics as well as for assessing community functionality will result in an increased understanding and a complete description of the gastrointestinal communities of production animals fed under different dietary regimes, and lead to new strategies for improving animal growth.

psXML: A New XML-based Standard Protocol for Service-oriented, Open Architecture of Consumer Portal (psXML: 서비스 중심적 개방형 아키텍처를 가지는 수용가포털을 위한 XML 기반의 표준화)

  • Hong, Jun-Hee;Choi, Jung-In;Kim, Jin-Ho;Kim, Chang-Sub;Son, Sun-Young;Choi, Jun-Young
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
    • /
    • v.21 no.10
    • /
    • pp.108-117
    • /
    • 2007
  • RConsumer Portal is defined as "a combination of hardware and software that enables two-way communication between energy service providers(ESP, like KEPCO) and equipment within the consumer's premises". The portal provides both a physical link(between wires, radio waves, and other media) and a logical link(translating among language-like codes and etiquette-like protocols) between in-building and wide-area access networks. Thus, the consumer portal is an important, open public shared infrastructure in the future vision of energy services. This paper presents an XML based standard specification of service-oriented, open protocol for consumer portal system architecture. In the framework level, the XML protocol provides a useful bridge between services and platforms. The proposed standard protocol has been implemented into our developing consumer portal pilot system. The results imply the potential of global standards for consumer portal system by its minimum overhead in network and processor. The reposed XML is designated psXML in this paper.

An Integrated Methodology of Knowledge-based Rules with Fuzzy Logic for Material Handling Equipment Selection (전문가 지식 및 퍼지 이론을 연계한 물류설비 선정 방안에 관한 연구)

  • Cho Chi-Woon
    • Journal of Intelligence and Information Systems
    • /
    • v.12 no.1
    • /
    • pp.57-73
    • /
    • 2006
  • This paper describes a methodology for automating the material handling equipment (MHE) evaluation and selection processes by combining knowledge-based rules and fuzzy multi-criteria decision making approach. The methodology is proposed to solve the MHE selection problems under fuzzy environment. At the primary stage, the most appropriate MHE type among the alternatives for each material flow link is searched. Knowledge-based rules are employed to retrieve the alternatives for each material flow link. To consider and compare the alternatives, multiple design factors are considered. These factors include both quantitative and qualitative measures. The qualitative measures are converted to numerical measures using fuzzy logic. The concept of fuzzy logic is applied to evaluation matrices used for the selection of the most suitable MHE through a fuzzy linguistic approach. Thus, this paper demonstrates the potential applicability of fuzzy theory in the MHE applications and provides a systemic guidance in the decision-making process.

  • PDF

The Influence of CEO's Scandal on Consumers' Product Purchase

  • CHOI, Ji-Eun
    • The Journal of Industrial Distribution & Business
    • /
    • v.11 no.4
    • /
    • pp.47-56
    • /
    • 2020
  • Purpose: This study aims to explore how consumers respond to the immoral actions of a CEO. More specifically, this research focuses on the moral reasoning processes used by consumers in order to maintain support for the CEO despite the immoral action. In addition, this research suggests that support for the CEO would improve product purchase intention. Research design, data, and methodology: To test the hypotheses presented, an online research company was hired and online survey was conducted with adult participants. Online research company sent an email to the potential subjects asking their participation in an online survey. Subjects were able to participate in the online survey by clicking a link to the survey. When the participants clicked the link, they were instructed to read a fictitious newspaper article on a CEO's immoral action. And then, they were asked to answer several questions online. Responses were obtained from 336 adults participants and data were analyzed using SPSS Hayes Macro for a moderation effect and AMOS for a structural equation model. Result: Moral reasoning processes were divided into moral decoupling and moral rationalization and analyzed to determine their influence on product purchase. Also in this study, we suggest the public self-consciousness of consumers as an antecedent of moral reasoning processes, and argue that consumers with high public self-consciousness are more likely to engage in moral decoupling than moral rationalization. Conclusions: Our results showed that moral decoupling and moral rationalization improved the consumer's perception of corporate ethicality, which increased product purchase intention. In addition, consumers with high public self-consciousness were more likely to engage in moral decoupling than in moral rationalization. In addition, this research suggested that severity of the scandal would moderate the impact of public self-consciousness on moral decoupling. However, this hypothesis was not supported statistically since most participants perceived the scandal to be a highly severe incident, that may lead to an insignificant interaction effect between severity of the scandal and public self-consciousness. This research expands the scope of available research on corporate ethics and consumer responses to negative information involving celebrities and provides practical implications for corporate crisis management.

Some Factors Affecting Germination and Growth of Echinochloa colona (Echinochloa colona의 발아(發芽) 및 생장(生長)에 미치는 제요인(諸要因))

  • Chun, J.C.;Moody, K.
    • Korean Journal of Weed Science
    • /
    • v.5 no.2
    • /
    • pp.103-108
    • /
    • 1985
  • A series of experiments were conducted to determine the effect of pH, salinity, seeding depth, and moisture stress on the germination and growth of Echinochloa colons (L.) Link. Germination significantly decreased at pH 10, but shoot lengths were not affected by the pH tested. Germination was not affected by salt concentrations of up to 0.1%, but was significantly reduced at 0.5%. A 1.0% salt concentration did not significantly reduce shoot length. Increase in seeding depth significantly reduced emergence. Irrespective of seeding depth, the coleoptilar node was always just below the soil surface. Delayed and decreased germination was obtained at -4.6 bars of simulated water potential, while no germination occurred at -9.8 bars. Soil moisture stress significantly reduced plant height, delayed panicle initiation, and reduced seed production.

  • PDF

IoT Enabled Smart Emergency LED Exit Sign controller Design using Arduino

  • Jung, Joonseok;Kwon, Jongman;Mfitumukiza, Joseph;Jung, Soonho;Lee, Minwoo;Cha, Jaesang
    • International journal of advanced smart convergence
    • /
    • v.6 no.1
    • /
    • pp.76-81
    • /
    • 2017
  • This paper presents a low cost and flexible IoT enabled smart LED controller using Arduino that is used for emergency exit signs. The Internet of Things (IoT) is become a global network that put together physical objects using network communications for the purpose of inter-communication of devices, access information on internet, interaction with users as well as permanent connected environment. A crucial point in this paper, is underlined on the potential key points of applying the Arduino platform as low cost, easy to use microcontroller with combination of various sensors applied in IoT technology to facilitate and establishment of intelligent products. To demonstrate the feasibility and effectiveness of the system, devices such as LED strip, combination of various sensors, Arduino, power plug and ZigBee module have been integrated to setup smart emergency exit sign system. The general concept of the proposed system design discussed in this paper is all about the combination of various sensor such as smoke detector sensor, humidity, temperature sensor, glass break sensors as well as camera sensor that are connected to the main controller (Arduino) for the purpose of communicating with LED exit signs displayer and dedicated PC monitors from integrated system monitoring (controller room) through gateway devices using Zig bee module. A critical appraisal of the approach in the area concludes the paper.

From the point of view of ground operations principle, Chosin Link-up operation discussion of the US 1st Marine Division (지상작전의 원칙 측면에서 미 제1해병사단의 장진호 연결작전 고찰)

  • Kim, Kyu-Bin;Choi, Yong-Yoel
    • Journal of National Security and Military Science
    • /
    • s.13
    • /
    • pp.1-41
    • /
    • 2016
  • US 8th Army in the attack on the Western Front was a situation that was frustrated by the 13th Corps Communist army. To this time support this, goals that have been granted to the US 1st Marine Division that initiated the attack in Mupyonri direction, lack the potential to achieve was not decisive. It was a operation specific erroneous judgment that occurred because there was no one accurately grasp the battlefield of the situation the wrong UN Forces Command. Tactical victory can be to maximize the operation outcomes. However, there is no possible failure of the operation is to expand the tactical success. This is because the failure of the operation, because directly linked to the success or failure of the war. Tactical victory can be to maximize the operation outcomes. However, operation specific failure is not it possible to expand the tactical victory. Therefore tactical success of the US 1st Marine Division, can not compensate for operation specific failure of the United Nations Forces Command. However, Chinese Communist Army 9th Corps is obsessed only victory of tactics to annihilate the US 1st Marine Division, by being fixation to the Chosin whole area, it was not possible to run a operational operation. Therefore tactical success df the US 1st Marine Division, Chinese Communist Army 9th Corps is to extinguish the ability to increase the number of the 13th Corps of the Western Front, 8th Army US have contributed to have escaped the crisis. In addition, the US 10th Corps while maintaining the combat force, by an important role to withdraw through the sea, was able to complement the misjudgment of the operation.

  • PDF