• Journal of the Korean Institute of Landscape Architecture
• /
• v.40 no.6
• /
• pp.161-172
• /
• 2012

The purpose of this study is to classify, evaluate and grade the existing highway tunnels to increase landscape and natural statistics keeping the structural safety about tunnel gates area and induce the ones that will be constructed in the future by drawing the improvements and restoring the techniques as an environment-friendly. To examine the types of tunnel gate area, total 54 tunnels were investigated by selecting Gyeongbu Expressway, Yeongdong Expressway, and Jungang Expressway. Tunnel entrances and exit ports were classified as a Wall-closed type and Protruding type, which is based on tunnel gate type. Vegetation Landscape types were classified as Multilayer-Same as the surrounding landscape_(MS), Multilayer-Difference of surrounding landscape_(MD), Single layer-Same as the surrounding landscape_(SS), Single layer-Difference of surrounding landscape_(SD), and a Desolate type which based on vegetation layers and environment-friendly. Potential vegetation recovery was identified based on the structural stability and revegetation potential of the tunnel. The factors include the structural stability of the slope height and slope gradient were selected. Revegetation potential was identified as a growth potential. This factor was used in the step to classify vegetation recovery potential of a tunnel. The result, which investigated the types of tunnel entrances and exit parts has found that the most typical in 33 places was a Wall closed type with 61.1% of the total ones. The case of vegetation landscape types was created but different from the ones surrounding it with 85.2% of the total ones. It is judged that the currently constructed vegetation of tunnel entrance and exit parts had put convenience on the safety and management before landscape consideration. In addition, tunnel entrance and exit parts with excellent potential for vegetation recovery were all Protruding type. In addition, it is judged that slope stability can easily obtain growth. Therefore, entrance and exist of the highway tunnels, which will be constructed in the future, should reflect location and the result of the natural and ecological survey in design by performing it in advance and their types, which minimize the damage area range, should be applied to the local characteristics suitably. In addition, the ecologically healthy tunnel construction should be done by introducing active vegetation recovery techniques based on its safety.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2006.05a
• /
• pp.180-188
• /
• 2006

수리 전도도는 hydraulic gradient에 대한 flux의 비율 또는, flux-hydraulic gradient 직선의 기울기를 나타내며, 포화된 토양에서의 물의 이동이 포화수리 전도도이고 불포화된 토양에서의 이동이 불포화수리전도도이다. 일반적인 밭 상태에서의 토양수분 조건은 불포화수리 전도도로 표시하는 것이 적절하나 그 상태를 표현하기가 쉽지 않다. 토양의 불포화 상태를 나타내는데 가장 많이 쓰이고 있는 VGM(van Genuchten Mualem) 모형은 토양수분 포텐셜과 수분함량의 함수로 구성된 모형이며 몇 가지 매개변수가 필요하다. VGM 모형의 매개변수를 얻기 위해 본 연구에서는 VGM 모형의 매개변수를 계산해주는 프로그램인 Rosetta를 사용하였다. Rosetta 모형은 신경그물 얼개(neural network)를 이용하여 토양의 물리적 자료들인 토성이나 모래, 미사, 점토 함량 또는 용적밀도나 33kPa, 1500kPa에서의 토양수분 함량 자료를 가지고 VGM의 매개변수인 Ko(effective saturated hydraulic conductivity), ${\theta}r$(residual soil water content), ${\theta}s$(saturated soil water content), L, n, m(=1-1/n)을 예측하는 모형으로 미국 농무성(USDA-ARS)에서 개발한 프로그램이다. Rosetta를 이용하여 10kPa에서의 불포화수리 전도도를 예측하였다. 또한 Gardner(1958)와 Wooding (1968)의 모형을 기반으로 하여 만들어진 tension infiltrometer의 포화수리 전도도 값을 Gardner 식에 적용하여 1, 3, 5, 7kPa에서의 불포화수리 전도도 값을 17개 토양통을 대상으로 하여 구했다. 토양수분 potential이 3kPa에서는 물의 이동이 거의 없는 토양들이 있었는데 반해 남계통을 비롯한 학곡통, 회곡통, 백산통, 상주통, 석천통, 예산통 등 7개의 토양은 3kPa에서도 약간의 물의 이동이 있었다. 이는 모암이 화강 편마암인 관계로 토양 내에 물의 이동에 영향을 미치는 자갈의 함량이 높았기 때문일 것으로 생각되고 추후의 연구에서는 이 부분에 대한 내용도 검토되어야 할 것이다. 또한, 1kPa에서 물의 이동은 삼각통에서 35.21 cm/day로 이동 속도가 가장 컸으며 그 뒤로 예산통, 화봉통, 학곡통, 백산통 등이 토양에서 빠른 속도로 이동하였다. 가천통이나 석천통 및 우곡통은 1kPa에서의 이동 속도가 아주 느린 토양으로 판단되었다. 또한, 포화되지 않은 상태인 1kPa에서 물의 이동 속도를 VGM 모형에 의해 예측된 값과 측정된 값으로 비교하였을 때 불포화 수리 전도도가 예측되지 않은 토양(석천통, 지곡통, 풍천통)이 존재하여 불포화 수리 전도도 특성평가에 대한 VGM 모형의 적용성에 문제를 보였다. 이는 결과적으로 논이라는 영농형태가 존재하는 우리나라에서 토양의 수리적 특성해석을 위한 VGM 모형의 적용성에 한계가 있을 것으로 판단되었다.

• Journal of Pharmaceutical Investigation
• /
• v.25 no.3
• /
• pp.7-20
• /
• 1995

Taurine, a ${\beta}-amino$ acid, plays an important role as a neuromodulator and is necessary for the normal development of the brain. Since de novo synthesis of taurine in the brain is minimal and in vivo studies suggest that taurine dose not cross the blood-brain barrier, we examined whether the choroid plexus, the blood-cerebrospinal fluid (CSF) barrier, plays a role in taurine transport in the central nervous system. The uptake of $[^3H]-taurine$ into ATP depleted choroid plexus from rabbit was substantially greater in the presence of an inwardly directed $Na^+$ gradient taurine accumulation was negligible. A transient in side-negative potential gradient enhanced the $Na^+-driven$ uptake of taurine into the tissue slices, suggesting that the transport process is electrogenic, $Na^+-driven$ taurine uptake was saturable with an estimated $V_{max}$ of $111\;{\pm}\;20.2\;nmole/g/15\;min$ and a $K_M\;of\;99.8{\pm}29.9\;{\mu}M$. The estimated coupling ratio of $Na^+$ and taurine was $1.80\;{\pm}\;0.122.$ $Na^+-dependent$ taurine uptake was significantly inhibited by ${\beta}-amino$ acids, but not by ${\alpha}-amino$ acids, indicating that the transporter is selective for ${\beta}-amino$ acids. Since it is known that the physiological concentration of taurine in the CSF is lower than that in the plasma, the active transport system we characterized may face the brush border (i.e., CSF facing) side of the choroid plexus and actively transport taurine out of the CSF. Therefore, we examined in vivo elimination of taurine from the CSF in the rat to determine whether elimination kinetics of taurine from the CSF is consistent with the in vitro study. Using a stereotaxic device, cannulaes were placed into the lateral ventricle and the cisterna magna of the rat. Radio-labelled taurine and inulin (a marker of CSF flow) were injected into the lateral ventricle, and the concentrations of the labelled compounds in the CSF were monitored for upto 3 hrs in the cisterna magna. The apparent clearance of taurine from CSF was greater than the estimated CSF flow (p<0.005) indicating that there is a clearance process in addition to the CSF flow. Taurine distribution into the choroid plexus was at least 10 fold higher than that found in other brain areas (e. g., cerebellum, olfactory bulb and cortex). When unlabelled taurine was co-administered with radio-labelled taurine, the apparent clearance of taurine was reduced (p<0.0l), suggesting a saturable disposition of taurine from CSF. Distribution of taurine into the choroid plexus, cerebellum, olfactory bulb and cortex was similarly diminished, indicating that the saturable uptake of taurine into these tissues is responsible for the non-linear disposition. A pharmacokinetic model involving first order elimination and saturable distribution described these data adequately. The Michaelis-Menten rate constant estimated from in vivo elimination study is similar to that obtained in the in vitro uptake experiment. Collectively, our results demonstrate that taurine is transported in the choroid plexus via a $Na^+-dependent,saturable$ and apparently ${\beta}-amino$ acid selective mechanism. This process may be functionally relevant to taurine homeostasis in the brain.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.43 no.1 s.307
• /
• pp.9-16
• /
• 2006

This Paper proposes an adaptive error diffusioThis paper proposes an adaptive error diffusion algorithm for text enhancement followed by an efficient text segmentation that uses the maximum gradient difference (MGD). The gradients are calculated along with scan lines, and the MGD values are filled within a local window to merge the potential text segments. Isolated segments are then eliminated in the non-text region filtering process. After the left segmentation, a conventional error diffusion method is applied to the background, while the edge enhancement error diffusion is used for the text. Since it is inevitable that visually objectionable artifacts are generated when using two different halftoning algorithms, the gradual dilation is proposed to minimize the boundary artifacts in the segmented text blocks before halftoning. Sharpening based on the gradually dilated text region (GDTR) prevents the printing of successive dots around the text region boundaries. The error diffusion algorithm with edge enhancement is extended to halftone color images to sharpen the tort regions. The proposed adaptive error diffusion algorithm involves color halftoning that controls the amount of edge enhancement using a general error filter. The multiplicative edge enhancement parameters are selected based on the amount of edge sharpening and color difference. Plus, the additional error factor is introduced to reduce the dot elimination artifact generated by the edge enhancement error diffusion. By using the proposed algorithm, the text of a scanned image is sharper than that with a conventional error diffusion without changing background.

• Journal of Life Science
• /
• v.21 no.7
• /
• pp.976-984
• /
• 2011

Total phenolic content was the highest in 60% ethanol extracts at 21.91 mg/g, and inhibitory activity against tyrosinase of 60% ethanol extracts was higher than ethanol extracts of other concentration. The inhibitory compounds against tyrosinase from Persimmon leaves were purified using Sephadex LH-20, MCI-gel CHP-20 column chromatography with gradient elution. Two purified compounds were isolated as a result. The chemical structures of each compound were determined and identified using $^1H$-NMR and $^{13}C$-NMR, FAB-Mass. The compounds were confirmed as (+)-gallocatechin and prodelphinidin B-3. The tyrosinase inhibitory activities of purified (+)-gallocatechin and prodelphinidin B-3 were 29.5 and 40.2%, respectively. The inhibitory activities of (+)-gallocatechin and prodelphinidin B-3 against melanin biosynthesis in melanoma cell were 32.5 and 46.7%. The safety of essence with tyrosinase inhibitory compounds from persimmon leaves was also assessed by various safety profiles. First, changes in pH (4.90~4.95) and viscosity (23,000~26,000 cP) was not detected for 60 days. Essence also showed stability against temperature and light for 60 days. All these findings suggest that extracts from persimmon leaves have a great potential as a cosmetical ingredient with a potent whitening effect.

• Journal of the Korean Magnetics Society
• /
• v.21 no.2
• /
• pp.43-47
• /
• 2011

It is known that the Fe-Al transition metal compounds have a lot of disagreement about structural stability and magnetism. In this study, the correlation between magnetism and atomic structure of ordered $B_2$, $L1_2$, and $D0_3$ structured Fe-Al compounds has been investigated using the all-electron full-potential linearized augmented plane wave (FLAPW) method based on the generalized gradient approximation (GGA). We found that considered all the structures were calculated to be stabilized in a ferromagnetic state. The calculated spin magnetic moments of the Fe atoms for B2 and $L1_2$ structures were 0.771 and 2.373 ${\mu}_B$, respectively, and that of Fe(I) and Fe(II) in $D0_3$ structure calculated to be 2.409 ${\mu}_B$, 1.911 ${\mu}_B$, respectively. In order to investigate structural stability between $L1_2$ and $D0_3$ structures, we performed the formation enthalpy calculations. As a result, the $D0_3$ structure is found to be more favorable than $L1_2 one by energy difference 16 meV/atom, which is well consistent with the experimental observation. We understood about structural stability and magnetism for Fe-Al compounds in terms of analysis of their atomic and electronic structures.

• The Bulletin of The Korean Astronomical Society
• /
• v.40 no.1
• /
• pp.66.3-67
• /
• 2015

Without scrutinizing reflection, the plasma comprising a coronal loop is usually regarded to reside within a flux rope. This picture seems to have been adopted from laboratory plasma pinches, in which a plasma of high density and pressure is confined in the vicinity of the flux rope axis by magnetic tension and magnetic pressure of the concave inward magnetic field. Such a configuration, in which the plasma pressure gradient and the field line curvature vector are almost parallel, however, is known to be vulnerable to ballooning instabilities (to which belong interchange instabilities as a subset). In coronal loops, however, ideal MHD (magnetohydrodynamic) ballooning instabilities are impeded by a very small field line curvature and the line-tying condition. We, therefore, focus on non-ideal (resistive) effects in this study. The footpoints of coronal loops are constantly under random motions of convective scales, which twist individual loop strands quite randomly. The loop strands with the axial current of the same direction tend to coalesce by magnetic reconnection. In this reconnection process, the plasma in the loop system is redistributed in such a way that a smaller potential energy of the system is attained. We have performed numerical MHD simulations to investigate the plasma redistribution in coalescence of many small flux ropes. Our results clearly show that the redistributed plasma is more accumulated between flux ropes rather than near the magnetic axes of flux ropes. The Joule heating, however, creates a different temperature distribution than the density distribution. Our study may give a hint of which part of magnetic field we are looking to in an observation.

• Food Science of Animal Resources
• /
• v.37 no.5
• /
• pp.654-662
• /
• 2017

Extracellular microvesicles are membranous nano-sized cellular organelles secreted by a variety of cells under normal and pathological conditions and heterogeneous in size ranging from 30 nm to $1{\mu}m$. They carry functional microRNAs that can influence immunity and development. For a particular application of microvesicles, choice of isolation method is particularly important; however, their isolation methods from colostrum in particular have not been described clearly. In this work, differential ultracentrifugation as a conventional method, ultracentrifugation with some modification such as additional precipitations, ultrafiltration, sucrose gradient separation and ExoQuick$^{TM}$ as a commercial reagent were compared. The goal was to compare mainly microvesicular total microRNA yield, distribution and purity among the methods then select the best isolation method for bovine colostrum microvesicles based largely on microRNA yield with the view of applying the vesicles in work where vesicular microRNA cargo is the target bioactive component. Highest yields for vesicular microRNA were obtained using conventional methods and among them, subsequent ultracentrifugation with 100,000 g and 135,000 g conventional method 2 was selected as it had the highest RNA to protein ratio indicating that it pelleted the least protein in relation to RNA an important factor for in vivo applications to assess microvesicle functionalities without risk of contaminating non-vesicular biomaterial. Microvesicles isolated using conventional method 2 were successfully internalized by cells in vitro showing their potential to deliver their cargo into cells in vitro and in vivo in case of functional studies.

• Smart Structures and Systems
• /
• v.19 no.2
• /
• pp.115-126
• /
• 2017

In this paper, size dependent bending and free flexural vibration behaviors of functionally graded (FG) nanobeams are investigated using a nonlocal quasi-3D theory in which both shear deformation and thickness stretching effects are introduced. The nonlocal elastic behavior is described by the differential constitutive model of Eringen, which enables the present model to become effective in the analysis and design of nanostructures. The present theory incorporates the length scale parameter (nonlocal parameter) which can capture the small scale effect, and furthermore accounts for both shear deformation and thickness stretching effects by virtue of a hyperbolic variation of all displacements through the thickness without using shear correction factor. The material properties of FG nanobeams are assumed to vary through the thickness according to a power law. The neutral surface position for such FG nanobeams is determined and the present theory based on exact neutral surface position is employed here. The governing equations are derived using the principal of minimum total potential energy. The effects of nonlocal parameter, aspect ratio and various material compositions on the static and dynamic responses of the FG nanobeam are discussed in detail. A detailed numerical study is carried out to examine the effect of material gradient index, the nonlocal parameter, the beam aspect ratio on the global response of the FG nanobeam. These findings are important in mechanical design considerations of devices that use carbon nanotubes.

• Advances in nano research
• /
• v.9 no.1
• /
• pp.15-24
• /
• 2020

Iron has a crucial role in growth as part of metalo-proteins like haemoglobin or myoglobin, enzymes; they are also involved in energetic reactions. Iron plays a vital role in fertility. At high doses, Iron has a harmful consequence on the reproductive system, which can be strongly reflected the final stage of spermatogenesis. Nutritional products are claiming to use nanotechnology and it is important to recognize the potential toxicity of nano-sized nutrients. Recently iron nanoparticles were proposed as a food additive for poultry. The objective of this study was to investigate the effects of L-cystein coated iron oxide nanoparticles on reproductive performance in male quails. The results of Fourier Transform Infrared Spectrometer, Alternating Gradient Force Magnetometer and Scaning Electron Microscopy showed that iron oxide nanoparticles was produced and have been coated with L-cycstein (Fe₃O₄-Cys NPs). A total of 100 one-week-old quail chicks were randomly placed to five groups of five replicates. Four quails (two male and two females) were raised in an individual cage for each replicate. The five experimental treatment diets consisted; negative control diet, with no Iron supplementation; positive control diet supplemented with 60 mg/kg of Fe₃O₄; treatment diets supplemented with 0.6, 6 and 60 mg/kg of L-cystein coated iron oxide nanoparticles. The hemoglobin, Red blood cell, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, gonadal somatic index, daily sperm production, total testicular sperm and sperm viability of the male quails that were fed with diet supplemented by 0.6 mg/kg of Fe₃O₄-Cys NPs were improved as compare with negative control. This study showed that not only the use of the Fe₃O₄-Cys nanoparticles had no side effects but also it can be used as a feed additive to improve the reproductive performance in male quails.