• Biomedical Science Letters
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• v.29 no.3
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• pp.121-129
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• 2023

Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects millions of people worldwide. The conventional treatment model for PD have harmful side effects, such as dyskinesia, hallucinations, nausea, and fatigue, and are expensive. As a result, natural products derived from medicinal herbs, fruits, and vegetables have emerged as potential therapeutic strategies for PD. These natural products have been traditionally used to treat various diseases and have been shown to possess anti-oxidative and anti-inflammatory properties, as well as inhibitory roles in protein misfolding, mitochondrial homeostasis, neuroinflammation and other neuroprotective processes. In addition, they have fewer side effects and are generally less expensive than conventional drugs. It also discusses the limitations of current treatments and the potential of natural remedies derived from plants to treat PD in new ways or as supplements to existing treatments. The multifunctional mechanisms of medicinal plants that may be utilized to treat PD are also discussed, including the modulation of neurotransmitter systems, the enhancement of neurotrophic factors, and the inhibition of apoptosis. While more research is needed to fully understand their mechanisms of action and efficacy, natural products have the potential to provide safer and more effective treatment options for patients with PD.

• Journal of The Korean Association For Science Education
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• v.22 no.2
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• pp.230-239
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• 2002

This study was performed to analyze the secondary students' perceptions and self-efficacy of performance assessments in the science subject. The data was obtained from 236 middle school students and 222 high school students in seoul. The students had generally proper understanding about characteristics of performance assessment which include purposes of assessment and differences from other conventional achievement assessments. They responded that the performance assessments were not useful in their science learning and developing their potential abilities. They were not satisfied with reliability and validity of the performance assessments. The middle school students more positively responded than high school students regarding the reliability of the scoring system and the originality of the evaluating materials. The female students more positively thought than males about the reliability of assessment and the usefulness for learning science. The students' self-efficacy level of performance assessment were not low in comparison with another existing assessments. They had high level of self-efficacy in understanding of experimental procedures, and utilizing of experimental apparatuses, but had low level of self-efficacy in understanding purposes of experiments or issues of discussions, processing of experimental results, answering of problems in experimental discussions. The female students' self-efficacy of performance assessment were higher than male students'. There was statistically correlated with females' scores and their level of self-efficacy of performance assessment.

• Journal of the Korea Society of Computer and Information
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• v.28 no.3
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• pp.137-148
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• 2023

The purpose of this study is to classify the potential types of mental health of mothers of multicultural youth by applying Latent Profile Analysis, analyze the influence of predictors, and find out how differences in potential types affect parental efficacy. To this end, panel data for the 9th year (2019) of the Multicultural Youth Panel Survey (MAPS) were used. As a result of the analysis, first, the mental health types of mothers of multicultural adolescents were analyzed in the order of 'middle risk type of mental health'(class3) > 'high risk type of self-esteem'(class1) > 'high risk type of mental health'(class4) > 'cultural adaptation and daily life stress'(class2). Second, compared to the "class 1" group, the lower the family economy level of multicultural youth mothers, the lower the educational background of multicultural youth fathers (husbands) graduate from middle school, the lower the level of Korean, and the lower the level of communication with children, the higher the odds of belonging to the 'mental health medium risk' group (Ods). Third, compared to the 'middle risk type of mental health'(class3) and 'high risk type of mental health'(class4), the 'high risk type of self-esteem'(class1) group was found to have a significant positive (+) effect on parental efficacy.

• Journal of Digital Convergence
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• v.11 no.8
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• pp.143-157
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• 2013

The purpose of this study is firstly, to find out the factors of entrepreneurial intention in potential entrepreneurs, and secondly to examine the relationship between objective start-up environment and subjective recognition of start-up environment, and entrepreneurial intention. For this study, investigation has been done to find out if fear of business failure, that is notoriously high among Koreans, acts as an influential factor between objective start-up environment/subjective recognition of start-up environment and entrepreneurial intention. The data is collected from 335 respondents comprised of college students and adults who are interested in starting their own businesses. The results of this study are as follows : (1) Objective start-up environment and subjective recognition of start-up environment, which is self-efficacy, have a positive effect on entrepreneurial intention. (2) Fear of business failure mediates the relationship between objective start-up environment/subjective recognition of start-up environment, and entrepreneurial intention (3) Child-care system, as an explain variable in the objective start-up environment in this study, is an important factor in the process of entrepreneurial commitment.

• Journal of Korean Academy of Nursing
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• v.46 no.4
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• pp.501-513
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• 2016

Purpose: The current challenges faced by nurses in providing high quality and evidence-based practice (EBP) supported care require profound changes in nursing education. To understand the changes needed to strengthen EBP education, the researchers examined EBP self-efficacy, course needs, barriers, and facilitators for academic faculty and clinical nurse preceptors to teach EBP in undergraduate nursing curricula. Methods: For this study, mixed-method approach was used with survey data collected from 73 academic faculty members from 54 universities. Further, 17 clinical nurse preceptors in three academic hospitals provided qualitative data for exploration of barriers and facilitators to teaching EBP. Data analysis used SPSS/WIN 21.0 and content analysis. Results: Quantitative data showed that although the overall level of self-efficacy among faculty was moderate, the implementation levels were relatively low. Most faculty members agreed with the need to integrate EBP courses into undergraduate nursing curricula. The qualitative data showed that the barriers to teaching EBP were lack of knowledge, skill, and initial investment for teaching EBP; hierarchical, rules-oriented nursing culture; potential learner overloads in processing EBP; limited research dissemination and application. Facilitators were identified as the importance of EBP to the profession of nursing; collaboration in schools and hospitals; and continuing education in teaching/utilizing EBP. Conclusion: The findings indicate that for successful integration of EBP ni nursing education there is a need for faculty training and integrated EBP courses.

• The Journal of the Korea Contents Association
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• v.17 no.4
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• pp.275-284
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• 2017

Modularity has merits in modifiability of product structure management and product arrangement. This feature helps consumer to expand the selection of products and to get customized products. Also consumers are drive satisfaction and reduce a post-purchase dissonance from role in a 'prosumer'. But expanding product's alternative would cause the overload confusion by rising complexity of information handling. Purpose of the study is to verify how interaction about option size and personal disposition are effected consumer's overload confusion. For this purpose we deducted 3 personal dispositions 'Regulatory focus', 'Product familiarity', 'Self-efficacy' that presented lead to potential effect of personal information handling by previous research. By statistical inquiry prevent focus group had perceived more overload confusion than promotion focus group in an expanding option size circumstances. And low Product familiarity and Self-efficacy group had perceived more overload confusion than high Product familiarity and Self-efficacy group in a expanding option size circumstances.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.4
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• pp.1644-1651
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• 2013

The purpose of this study was to investigate the influence of distance education experience using users' avatars in virtual reality space on their teaching efficacy belief. There were 9 participants who were enrolled in a course in doctoral program of education department in J University for the study. The first class of six sessions was face to face class on how to use Second Life and the 14 classes of 3 sessions were done in a classroom of Second Life. According to the analysis of reflection notes, interviews, researcher's observations of 5 participants, their experiences of presentation and taking classes in distance education using their own avatars in Second Life had positive influence on participants' teaching efficacy belief in their future working for distance education using avatars of Second Life. The implication of this study is to show some conditions for successful distance education as well as to see the potential of distance education in 3D virtual reality space using avatars. This study will contribute to promote the future study in distance education field.

• The Korean Journal of Pain
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• v.28 no.1
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• pp.11-21
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• 2015

Background: Epidural injections are performed utilizing 3 approaches in the lumbar spine: caudal, interlaminar, and transforaminal. The literature on the efficacy of epidural injections has been sporadic. There are few high-quality randomized trials performed under fluoroscopy in managing disc herniation that have a long-term follow-up and appropriate outcome parameters. There is also a lack of literature comparing the efficacy of these 3 approaches. Methods: This manuscript analyzes data from 3 randomized controlled trials that assessed a total of 360 patients with lumbar disc herniation. There were 120 patients per trial either receiving local anesthetic alone (60 patients) or local anesthetic with steroids (60 patients). Results: Analysis showed similar efficacy for caudal, interlaminar, and transforaminal approaches in managing chronic pain and disability from disc herniation. The analysis of caudal epidural injections showed the potential superiority of steroids compared with local anesthetic alone a 2-year follow-up, based on the average relief per procedure. In the interlaminar group, results were somewhat superior for pain relief in the steroid group at 6 months and functional status at 12 months. Interlaminar epidurals provided improvement in a significantly higher proportion of patients. The proportion of patients nonresponsive to initial injections was also lower in the group for local anesthetic with steroid in the interlaminar trial. Conclusions: The results of this assessment show significant improvement in patients suffering from chronic lumbar disc herniation with 3 lumbar epidural approaches with local anesthetic alone, or using steroids with long-term follow-up of up to 2 years, in a contemporary interventional pain management setting.

• Korean Journal of Food Science and Technology
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• v.53 no.2
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• pp.115-120
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• 2021

Scutellaria baicalensis has been used as a traditional medicine for diarrhea, dysentery, hypertension, hemorrhaging, insomnia, inflammation, and respiratory infections. This study examined the anti-inflammatory effect of Scutellaria baicalensis water extract (SWE) in lipopolysaccharide (LPS)-induced RAW 264.7 cells. To evaluate the anti-inflammatory effect of SWE, RAW 264.7 macrophages were stimulated with LPS to induce the production of inflammation-related factors, which were measured by western blotting. In RAW 264.7 cells, SWE inhibited the production of nitric oxide (NO) without causing cell toxicity. SWE also reduced the expression of inducible NO synthase and cyclooxygenase-2 protein, as well as the production of pro-inflammatory cytokines (such as tumor necrosis factor-α). The phosphorylation levels of the mitogen-activated protein kinase family members, such as JNK and p38, were also reduced by SWE. Thus, SWE could be used as a potential anti-inflammatory agent.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.3
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• pp.1-13
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• 2015

Strong ties such as family members, relatives and close friends have been widely acknowledged as a vital factor when a potential entrepreneur attempts to initiate entrepreneurial activity. Recent theoretical arguments focus that family social capital, a form of social capital, that is embedded in family relationships can contribute to venture creation as well as to the development of competitive advantage for established firms. Meantime, there have been arguments that the most dominant single entrepreneurial ethnic group in the world is the Chinese people, while the People's Republic of China is widely recognized as fast growing economic power that is driven by entrepreneurial ventures in a large scale. This study tests the effect of perceived relational supports typically being provided by family members, close relatives and friends on forming self-efficacy and entrepreneurial motivation of university students by using samples collected from 4 Korean Universities(Wonkwang, Baekseok, Soongsil and Dankook university) and Guangzhou University in China. The mediating of self-efficacy was also tested to gain better understanding of the role of the variable. The results of the study suggest that 1) both self-efficacy and entrepreneurial motivation are influenced positively by the perceived relational supports, 2) self-efficacy of university students affects their entrepreneurial motivation positively, 3) self-efficacy is appeared to be mediated partially for China in between perceived relational supports and entrepreneurial motivation, but the same variable is exhibited a full mediation in the same path of the research model for Korea, which was a distinction between the students of two countries in this study. Discussion and practical implication on the results are provided.