• Title/Summary/Keyword: postmortem investigation

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Postmortem Concentration of Carisoprodol

  • Choi, Hwa-Kyung;Lee, Ju-Seon;Choi, Hye-Young;Park, Yoo-Sin;Chung, Hee-Sun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.170.1-170.1
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    • 2003
  • Carisoprodol(CSP), commonly prescribed as a skeletal muscle relaxant, is increasingly abused among young people for a recreational purpose in Korea. CSP may induce hallucination if it were ingested with large amounts, futhermore a carisoprodol overdose is considered fatal. Recently, we encountered overdoses of carisoprodol in 6 suicide cases. (omitted)

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Vascular anatomy and their variations in Situs inversus totalis using postmortem computed tomographic angiography

  • Dawa Zangpo;Hironobu Nakane;Morio Iino
    • Anatomy and Cell Biology
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    • v.56 no.1
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    • pp.155-159
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    • 2023
  • Studies describing the vascular systems and their variations in Situs inversus totalis (SIT) from a whole-body computed tomographic (CT) angiography perspective are lacking. We report a case of SIT in which postmortem CT angiography (PMCTA) was performed as a part of the forensic death investigation and incidentally detected several vascular variations in it. The PMCTA procedure was performed using the multiphase PMCTA protocol. Almost all major vessels were visualized, indeed in a completely reversed pattern. Contrast mixture flow interruptions were noted in the right coronary arterial branches suggesting possible blockage, upon which autopsy revealed >90% vessel occlusions at several locations. As such the cause of death was due to ischemic heart disease. Anomalous origins of the right internal mammary artery; abnormal left thyrocervical trunk and variations in the drainage of testicular veins were noted. Our findings might be helpful to clinicians and add to the body of literature on SIT.

Analysis of Blood Toluene and Butane in Death Cases of Inhalant Abusers (사망사고 관련된 유해화학 물질 남용자들의 혈액 중 톨루엔과 부탄의 분석)

  • Kim, Nam-Yee;Yang, Young-Geun;Chung, Hee-Sun;Park, Sung-Woo
    • Analytical Science and Technology
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    • v.12 no.6
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    • pp.577-582
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    • 1999
  • The blood toluene concentration was determined by using the GC/MSD with HS-SPME technique in postmortem blood, quantitatively. Butane gases was analyzed by using the GC/FID with HS technique in postmortem blood, qualitatively. Seventy five cases of dead associated with inhalation of glue or butane gases happened in Korea for the last 3 years (1996-1998). In 27 cases of deah due to glue sniffing, nine persons died as a result of a fall while intoxication and their blood tolucne concentration was fairly high in the range of $1.3{\sim}21.6{\mu}g/mL$. In case of death due to butane sniffing, fifty four persons died of acute butane gases inhalation or suffocation, and 6 persons died of butane gases as well as glue inhalation.

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Demographic Characteristics of Zipeprol-associated Deaths in Korea

  • Chung, Hee-Sun;Choi, Hwa-Kyung;Kim, Eun-Mi;Park, Mee-Jung;Chung, Kyu-Hyuck;Yoo, Young-Chan
    • Archives of Pharmacal Research
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    • v.21 no.3
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    • pp.286-290
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    • 1998
  • The abuse of zipeprol, an antitussive agent, was found to be most prevalent among young people in Korea. Because abusers take large doses of this drug for its hallucinogenic effects, fatalities from zipeprol overdose abuse have been on the rise since 1991. Since 1991, a total of 69 zipeprol-related deaths have occurred throughout the nation. A demographic study shows that in ninety six percent of cases involving zipeprol alone, the victims were in their teens and twenties. The mate/female ratio in zipeprol related death was 3.5:1. Most of these zipeprol-associated deaths occurred in the larger cities of Seoul and Inchon. The blood concentration of zipeprol ranged from 0.8 to $38.3{\mu}g/mL $in single drug involved deaths, while zipeprol varied from to 35.3 $0.1{\mu}g/mL $in zipeprol and dextromethorphan victims.

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Reform of Medicolegal Death Investigation System in Korea - On the Professionalism of involved Personnel - (검시제도(檢視制度)의 개혁(改革) 방안(方案) - 검시 관여자(檢視 關與者)의 전문성(專門性)을 중심으로 -)

  • Seo, Young-Il;Chae, Jong-Min;Park, Hee-Kyung
    • Journal of forensic and investigative science
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    • v.1 no.2
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    • pp.44-56
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    • 2006
  • The reform necessity of medicolegal death investigation system is continuously issued. The problems from the current death investigation system are discussed, specially on the professionalism of the involved personnel such as policemen, doctors, prosecutors. Death investigation exists not only to prosecute the criminals but also primarily to protect the general public's health, safety, and welfare. The reform proposals of death investigation system are followed as below. Statutes require that the prosecutor be notified of certain deaths. All deaths that may reasonably result from anything other than natural disease should be investigated. A death certificate is a legal document which authenticate a death, therefore it is issued by the doctor. The postmortem examination must be rearranged on the university base and performed by the qualified doctors who are trained at least in pathology. The police officer specified in death investigation and forensic identification should be encouraged to keep doing their special work in many ways.

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Acute cocaine intoxication in a body packer

  • Park, Mee-Jung;Lim, Mi-Ae;Chung, Hee-Sun
    • Analytical Science and Technology
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    • v.19 no.1
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    • pp.103-106
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    • 2006
  • A 35-year-old Perubian who suffered from grand mal seizures died in the aircraft on his way from the United States to Hongkong via Incheon international airport of Korea. While performing the autopsy, 115 packs made with double layer of transparent film and black plastic bag containing cocaine were found in the ileum and large intestine. Among of them, 3 packs were ruptured. To determine the concentration of cocaine and its metabolites, blood, urine, bile, liver, spleen, heart, kidney, brain and gastric contents were taken and toxicological analysis was performed. Gas chromatography/mass spectrometry (GC/MS) following liquid-phase extraction using chloroform:isopropanol (=9:1) and derivatization with bis(trimethylsilyl)-trifluoroacetamide (contains 1% trimethylchlorosilane) was performed. High levels of cocaine, benzoylecgonine (BE) and ecgonine methylester (EME) were found in the postmortem blood (0.96, 3.09 and $5.59{\mu}g/mL$) and urine (32.85, 145.35 and $53.17{\mu}g/mL$), respectively. Cocaine and its metabolites were also detected in all other biological specimen.

A Study of Professor and College Students' Consciousness about a Fashion Internship (패션 인턴십에 대한 교수 및 학생의 의식 연구)

  • Yu Ji-Hun
    • Journal of the Korean Society of Costume
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    • v.55 no.8 s.99
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    • pp.30-47
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    • 2005
  • The purposes of this study were to analyze the consciousness of the professors and college students about the fashion industry internship and to provide basis data which were to develop an internship program of the fashion company and university and to activate it. The whole country were classified as Seoul and Gyeonggi division, Gangwon division, Chungchung division, Yeongnam division, and Honam division for this study. As object of the questionnaire, the professors of 50 universities and 132 college students from every division were selected by stratified cluster sampling. The investigation tool for this study was composed of 95 items for two kinds of professor's and two kinds of college student's survey. The question results were analyzed by frequency analysis and variance analysis, t- test and f- test by spss 10.0. The contents of research result were as follows : First, it arranged the opinions of the college students and professors about the internship experience and execution reason, the internship application methods and execution contents, the type of preference company and worked company, the company education contents, internship evaluation and postmortem. It also proposed the roles of the academic world, fashion industry circles and government for the internship activation.

Effect of Environmental Conditions on Estimation of Ambient Temperature for Minimum Postmortem Interval (PMI) in Korea (사후 경과시간 추정을 위한 현장 대기온도 예측에 국내 환경 조건이 미치는 영향)

  • Jeong, Su Jin;Park, Ji Eun;Lee, Hyo Jung;Park, Seong Hwan;Shin, Sang Eon;Lee, Jae Won
    • Journal of Science Criminal Investigation
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    • v.11 no.3
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    • pp.178-185
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    • 2017
  • It is one of the most important factors to statistical estimation of ambient temperature for accumulated degree day (ADD) and minimum postmortem interval (PMI) in the incident scene. Until now, we applied the temperature of the nearest weather stations, adjusted temperature, or estimated the temperature by the linear regression analysis to estimate the temperature of the incident site. At this time, the estimated temperature may be changed according to the method of temperature estimation. And The accuracy of the estimated value may also vary depending on the environmental factors such as capacity, wind speed, humidity, and rainfall, which may affect measurement conditions and temperature. Therefore, we studied the effect of various environmental factors and measurement conditions for ambient temperature in Korea.

The Usefulness of Rapid Triple Test for Cardiac Marker in Forensic Paragnosis of Sudden Cardiac Death (심장표지물질 간이검사의 급성심장사 법의학적 사후진단 유용성에 관한 연구)

  • Lim, Chae-Won;Kim, Jin-Gak
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.2
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    • pp.108-113
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    • 2017
  • A sudden cardiac death (SCD) is defined as an unnatural sudden death caused by heart disease. To determine the cause of death, observation of the microscopic change in cardiac muscle tissue is suggested, rather than visual postmortem examination. However, this suggestion is time consuming to be applied in the field, is cost-ineffective, and is inconvenient. Therefore, the purpose of this study is to understand whether temporary inspection used to examine the cardiac marker (Myoglobin, CK-MB, cTn I) in postmortem blood via rapid cardiac triple test kit (which is used by clinics to diagnose patients with acute myocardial infarction) can effectively be utilized for the paragnosis of sudden, unnatural cardiac death. The results of postmortem examination and temporary investigation found that 23 groups (76.7%), among the 30 experimental groups, were assumed to be non-traumatic sudden cardiac deaths, which indicated a positive response (according to comparison with forensic autopsy); 4 groups, among the 10 control groups, were assumed to be cerebrovascular disease, which indicated a negative response; 1 group was assumed to be alcoholic and drug poisoning, indicating a positive response; and 1 group was assumed to be oxygen deficiency due to suffocation, indicating a positive response. Hence, it was found that the level of sensitivity and specificity of cardiac marker's temporary inspection showed significant result, 76.7% and 80% respectively. Given this, temporary inspection can be effectively used for the paragnosis of sudden cardiac death when the medical history, situation of the site, and postmortem interval are considered together. With the result of precedent research on time of first revelation and extinction in blood, and difference in concentration over time progress according to the characteristic of cardiac marker's (myoglobin, CK-MB, cTn I) individual material, further research on concentration of cardiac marker per each post time needs to be conducted in order to estimate time science death (which is required to identify the cause of death and investigation).

Hypertrophic cardiomyopathy secondary to severe right and left ventricular outflow tract obstruction in a Maltese dog

  • Yoon, Won-Kyoung;Suh, Sang-Il;Oh, Yeon-Su;Hyun, Changbaig
    • Korean Journal of Veterinary Research
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    • v.55 no.3
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    • pp.209-211
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    • 2015
  • An 8-year-old spayed female Maltese (2.5 kg of body weight) presented with the primary complaint of loud heart murmur and exercise intolerance. Diagnostic imaging revealed severe pulmonic stenosis (peak velocity 5.2 m/s) with right ventricular hypertrophy. The dog revisited after 2 years, at which time, diagnostic imaging revealed severe biventricular hypertrophy, dynamic left ventricular outflow tract obstruction, left atrial dilation and pulmonary hypertension with worsened pre-existing pulmonic stenosis. Postmortem investigation revealed hypertrophic cardiomyopathy and regional myocardial infarction. The case was diagnosed as hypertrophic cardiomyopathy secondary to severe right and left ventricular outflow tract obstruction.