• Title/Summary/Keyword: post-2012

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Effects of NEES on PARP Expression in the Corpus Striatum in Rats Induced with Transient Global Ischemia

  • Lee, Jung Sook;Song, Young Wha;Kim, Sung Won
    • Journal of International Academy of Physical Therapy Research
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    • v.3 no.2
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    • pp.429-434
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    • 2012
  • Ischemia, the leading cause of strokes, is known to be deeply related to synaptic plasticity and apoptosis in tissue damage due to ischemic conditions or trauma. The purpose of this study was to research the effects of NEES(needle electrode electrical stimulation) in brain cells of ischemia-induced rat, more specifically the effects of Poly[ADP-ribose] polymerase(PARP) on the corpus striatum. Ischemia was induced in SD mice by occluding the common carotid artery for 5 minutes, after which blood was re-perfused. NEES was applied to acupuncture points, at 12, 24, and 48 hours post-ischemia on the joksamri, and at 24 hours post-ischemia on the hapgok. Protein expression was investigated through PARP antibody immuno-reactive cells in the cerebral nerve cells and western blotting. The number of PARP reactive cells in the corpus striatum 24 hours post-ischemia was significantly(p<.05) smaller in the NEES group compared to the global ischemia(GI) group. PARP expression 24 hours post-ischemia was very significantly smaller in the NEES group compared to the GI group. Results show that ischemia increases PARP expression and stimulates necrosis, making it a leading cause of death of nerve cells. NEES can decrease protein expression related to cell death, protecting neurons and preventing neuronal apoptosis.

Ischiorectal Block with Bupivacaine for Post Hemorrhoidectomy Pain

  • Rajabi, Mehdi;Hosseinpour, Mehrdad;Jalalvand, Faranak;Afshar, Mohammad;Moosavi, Golamabbas;Behdad, Samin
    • The Korean Journal of Pain
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    • v.25 no.2
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    • pp.89-93
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    • 2012
  • Background: Hemorrhoid is one of the most common surgical diseases occurring in the anorectal region. In this study, we evaluated the effect of ischiorectal fossa block on alleviating post hemorrhoidectomy pain. Methods: In this study, 90 patients suffering from hemorrhoids were evaluated. They were randomly divided into 3 groups. The first group had no block, the second group an ischiorectal block with placebo (normal saline), and the third group a preemptive ischiorectal block with bupivacaine. Postoperative variables such as pain intensity, pethidine consumption, nausea, and vomiting were compared between the groups. Results: The postoperative pain score in group 1 was $8.5{\pm}1.3$ and $8.1{\pm}0.9$ (P=NS) in group 2. The post operative analgesic demand was $3.1{\pm}1.5$ and $3.3{\pm}1.8$ hours in groups 1 and 2, respectively (P=NS). The post operative pain score and analgesic demand were $4.2{\pm}2.1$ and $9.3{\pm}2.7$ hours, respectively, in group 3 (P < 0.0001). Conclusions: Preemptive ischiorectal block reduces the posthemorrhoidectomy pain and opioid demand.

Error Analysis for Microwave Permittivity Measurement using Post Resonator Method (Post Resonator 방법에 의한 마이크로파 유전율 측정에서의 오차 분석)

  • Cho, Mun-Seong;Lim, Donggun;Park, Jae-Hwan;Park, Jae-Gwan
    • Journal of the Microelectronics and Packaging Society
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    • v.19 no.3
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    • pp.43-48
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    • 2012
  • Errors of relative permittivity calculation caused by the variation of sample aspect ratio (diameter/height) and measuring geometry were analyzed by computer simulation and measurement. Firstly, the $S_{21}$ spectrum of the sample (permittivity 38) was simulated in the post resonator measuring apparatus by HFSS simulation. Then, the relative permittivity was calculated from the $TE_{011}$ mode resonant frequency. The relative permittivity varied by ca. 0.3% with sample aspect ratio variation (D/H=0.8~1.6). The relative permittivity varied by ca. 1~10% when the 1~10% of air-gap was introduced in between the dielectric disk and upper conductor. All the simulation results showed consistent tendency with real measurement.

The Effects of Pre-operative Visual Information and Parental Presence Intervention on Anxiety, Delirium, and Pain of Post-Operative Pediatric Patients in PACU (회복실에 대한 사전 정보제공과 보호자 상주 중재가 수술 직후 각성 시 소아 청소년 환아의 불안, 섬망 및 통증에 미치는 효과)

  • Yoo, Je-Bog;Kim, Min-Jung;Cho, Soo-Hyun;Shin, Yoo-Jung;Kim, Nam-Cho
    • Journal of Korean Academy of Nursing
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    • v.42 no.3
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    • pp.333-341
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    • 2012
  • Purpose: The purpose of this study was to test whether pre-operative visual information and parental presence had positive effects on anxiety, delirium, and pain in pediatric patients who awoke from general anesthesia in a post-surgical stage. Methods: This study used a non equivalent control-group post test design (n=76). Independent variables were provision of pre-operative visual information and parental presence for post-surgical pediatric patients in PACU (post anesthesia care unit). Dependent variables were anxiety, delirium, and pain in the pediatric patients measured three times at 10 minute intervals after extubation in the PACU. Measurements included Numerical Rating Scale for assessing state anxiety, Pediatric Anesthesia Emergence Delirium Scale by Sikich & Lerman (2004) for delirium, and Objective Pain Scale by Broadman, Rice & Hannallah (1988) for pain. Results: Experimental group showed significantly decreased state anxiety at time points-10, 20, and 30 minutes after extubation. Delirium was significantly lower at 10 minutes and 30 minutes after extubation in the experimental group. Pain was significantly lower at 10 minutes after extubation in the experimental group. Conclusion: The results of this study suggest that this intervention can be a safe pre-operative nursing intervention for post-surgical pediatric patients at PACU.

The Effects of Repeated Passive Movement of Different Velocities on Knee Joint Position Sense in Patients With Post-Stroke Hemiplegia

  • Jo, Su-Jin;Choi, Jong-Duk
    • Physical Therapy Korea
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    • v.19 no.3
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    • pp.98-104
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    • 2012
  • The aim of this study was to examine the effects of repeated passive movement (RPM) of different velocities on the improvement of knee joint position sense (JPS) in post-stroke patients with hemiplegia, thereby investigate the possibility of clinical application in the initial stage of rehabilitation for patients with post-stroke hemiplegia. Thirteen hemiplegic patients participated in this study. For the subjects' knee JPS tests, a passive angle reproduction test and an active angle reproduction test were performed prior to and after the intervention, which involved 30 repetitions of passive full-range-of-motion flexion and extension exercise of the knee joints at randomized degrees of $0^{\circ}/s$, $45^{\circ}/s$, and $90^{\circ}/s$. Paired t-test analysis was done in order to compare changes in the pre- and post-intervention knee JPS. One-way repeated analysis of variance was used in order to compare changes in JPS after intervention at three different movement velocities. The level of significance was set at .05. The result was that the subjects' post-intervention knee JPS significantly improved after the RPM exercise at a $45^{\circ}/s$ and a $90^{\circ}/s$ relative to the RPM exercise $0^{\circ}/s$ (p<.05). JPS changes with RPM intervention at the rapid velocity of $90^{\circ}/s$ were most increased, suggesting the most effective enhancement in knee JPS is with intervention at the velocity (p<.05). Therefore, RPM intervention at a half or higher velocity improved stroke patients' knee JPS. During the initial stage of rehabilitation for patients with post-stroke hemiplegia, the efficient application of the RPM exercise at a half or higher velocity will be possible.

Prognostic Sub-Grouping of Diffuse Large B-Cell Lymphomas into Germinal Centre And Post Germinal Centre Groups by Immunohistochemistry after 6 Cycles of Chemotherapy

  • Hassan, Usman;Mushtaq, Sajid;Mamoon, Nadira;Asghar, Asghar Hussain;Ishtiaq, Sheeba
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1341-1347
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    • 2012
  • Introduction: Diffuse large B-cell lymphomas (DLBCL) can be divided into germinal centre (GC-DLBCL) and post germinal centre (post GC-DLBCL) groups by applying immunohistochemical antibodies. As these subgroups respond differently to chemotherapy, it is possible at diagnosis to select a poor prognostic subgroup for aggressive treatment. Objective: To determine the frequencies of GC-DLBCL and post GC-DLBCL in patients by immunohistochemistry (IHC) and the clinical response after six cycles of chemotherapy. Subjects and Methods: In this descriptive study conducted in AFIP and CMH, Rawalpindi and NORI, Islamabad, from September 2010 to September 2011, a total of 75 pretreatment cases of DLBCL diagnosed during the study period were included. Cases were segregated in to GC-DLBCL and post GC-DLBCL groups according to results of immunohistochemistry markers CD10, BCL6 and MUM1. Immediate clinical response was assessed after 6 cycles of chemotherapy. Response was divided into complete response, partial response, stable disease or relapse or progression. Results: The mean age was $54.2{\pm}15$. Males were 53 (70.7%). Forty (53.3%) cases comprised the GC-DLBCL group; 25(62.5%) of them showed a complete response. Most patients of the post GC-DLBCL 19(54%) showed relapse/progression. Results of immediate clinical response in both prognostic subgroups were significant (p<0.05). Results regarding positivity with immunohistochemical antibodies CD10 (p 0.011), BCL6 (p 0.013) and MUM1 (p 0.000) regarding immediate clinical response were also significant. Conclusion: GC-DLBCL group shows better response to CHOP chemotherapy regimen. Immunohistochemistry should be used to further classify DLBCL as this can enable us to select aggressive group for aggressive treatment. This manuscript is important because the study is the first to becarried out exclusively in Pakistan or our part of the world.

The Ex-ante and Ex-post Effects of the Price Stabilization Policies on IPO underpricing in KOSDAQ Markets (유가증권 시장조성제도가 코스닥IPO시장의 사전적 및 사후적 저평가에 미친 영향)

  • Kim, Soo-Hyun;SonU, Suk-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.1
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    • pp.156-163
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    • 2012
  • The price stabilization policies which require the underwriters to maintain post-IPO prices at some level (stabilization duty) or give put-back options to investors, have survived for eight years until June, 2006. The purpose of this study is to analyze the effect of price stabilization policies upon IPO underpricing in KOSDAQ. The study decomposes the influence of the price stabilization policies on IPO underpricing into ex-ante and ex-post effect. The price stabilization policies have shown to increase the IPO underpricing both at ex-ante and ex post bases. And the ex-ante effect is greater than ex-post effect. Among policies, the price stabilization duty magnifies the underpricing more than put-back option. This study differentiate from the precedented studies by including the whole period in which those policies are in act and by decomposing the IPO underpricing effects into ex-ante and ex-post bases.

An Analysis of the Post-viewing Emotion and Behavior on the Dance Audience (무용공연 관람객의 관람 후 감정과 행동 분석)

  • Choi, Chung-Ja;Kim, Hyung-Nam;Shim, Hyun-Hwa
    • The Journal of the Korea Contents Association
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    • v.12 no.7
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    • pp.147-155
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    • 2012
  • This study is to analyze the difference of the post-viewing emotion and behavior of the audience at a dance performance by general characteristics of the audience. To attain the goal of the study described above paragraphs, the audience of dance performance located in Seoul and Kyoungki-Do was set as a collected group. Then, using the convenience sampling method, finally drew out and analyzed 280 people in total. statistic analysis techniques were used SPSS 18.0 program. Based on the statistical methods above, we had the result of data analysis as follows; First, among the general characteristics(job, viewing frequency, dance experience, and genre), had significantly effect on the post-viewing emotion(positive emotion, satisfaction) Second, among the general characteristics(job, viewing frequency, dance experience, and genre), all the factors had significantly effect on post-viewing behaviors(researching, respectating intention).

The Effects of Life Changes on Post-Traumatic Stress Disorder after Disasters (재난 후 생활변화가 외상 후 스트레스 장애에 미치는 영향)

  • Lim, Hye Sun;Sim, Kyungok
    • Stress
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    • v.26 no.4
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    • pp.319-326
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    • 2018
  • Background: This study investigated whether pre- and peri-disaster experiences influence on PostTraumatic Stress Disorder (PTSD) and whether post-disaster stress by life changes have impact on PTSD after controlling pre- and peri-disaster factors. Methods: Data came from a sample of 1,182 respondents who experienced natural disasters (flood and typhoon) in South Korea from 2012 to 2015. The SPSS Win 22.0 program was used for descriptive analysis, t-test, Chi-square test, Pearson's correlation and logistic regression analysis. Results: The results indicated that 24.3% of the disaster victims were in PTSD risk group. Compared with non-PTSD, PTSD risk group showed lower interpersonal trust and satisfaction, higher depression and anxiety, and lower subjective well-being. The results of hierarchical logistc regression revealed that all pre-, peri-, and post-disaster factors increased the probability of developing PTSD, except for relocation of residence. Moreover, a primary post-disaster predictor of PTSD was economic distress after controlling for pre- and peri-disaster. Conclusions: This study tested relative contributions of post-disaster factors on PTSD.

Effects of Acute Soccer Game on Serum Levels of Neurotrophins and Neurocognitive Functions in Male Adolescents (1회성 축구활동이 남자 청소년의 혈청 neurotrophins 수준과 신경인지 기능에 미치는 영향)

  • Yang, Jung-Su;Yoo, Shin-Hwan;Cho, Su-Youn;Roh, Hee-Tae
    • Journal of Life Science
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    • v.22 no.11
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    • pp.1444-1450
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    • 2012
  • The purpose of the present research is to investigate the effects of acute soccer game on serum levels of neurotrophins and neurocognitive function. The subjects of the research were 15 healthy male adolescents. The subjects underwent two experiments: one experiment in the soccer game treatment (SOC) condition, and the other in the self-study treatment (CON) condition. Blood samples were collected at three times: before treatment (Pre), after treatment (Post), and 2 hours post treatment (Post-2 h) for the analyses of serum brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and insulin-like growth factor-1 (IGF-1). For the measurements of neurocognitive functions, the Stroop Color-Word test was performed at blood collecting times. The results of the research showed that the serum levels of BDNF, NGF, and IGF-1 were significantly increased after the soccer game (p<0.05), and significantly higher in SOC than CON at Post (p<0.05). In the Stroop Color-Word test, significantly increased scores were observed in SOC at Post (p<0.05), and significantly higher in SOC than in CON at Post and Post-2 h (p<0.05). These results suggest that acute soccer game has positive effects on neurocognitive functions by increasing the neurotrophins.