• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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• pp.270-270
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• 2008

We present details of experimental results in the fabrication of high density line patterns, using imprint technique that can provide a simple and comparatively cost-effective manufacturing means. Barrier array structures for display or interconnects for semiconductor applications were the aims of this study. For pattern fabrication, a polymer layer (Ajinomoto GX-13 dielectric film) with a thickness of 38um that can act as either an insulating or a dielectric layer was laminated on a substrate. Fine tracks were then formed using a patterned stamp under isostatic pressure. The line width was ranged between 10 to 60 mm. A self-assembled monolayer (SAM) of fluorinated alkylchlorosilane [$CF_3(CF_2)5(CH_2)2SiCl_3$] as an anti-sticking layer was coated on the surface of the stamp prior to thermal imprint to improve the de-molding characteristic.

• 대한의생명과학회지
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• 제25권4호
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• pp.398-406
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• 2019

Cancer immunotherapy using gene-modified tumor cells is safe and customized cancer treatment method. In this study, we made gene-modified tumor cells by transferring costimulatory molecules, 4-1BBL and OX40L, into tumor cells using lentivirus vector, and identified anti-cancer effect of gene-modified tumor cells in CT26 mouse colorectal tumor model. We construct pLVX-puro-4-1BBL, -OX40L vector for lentivirus production and optimized the transfection efficiency and transduction efficiency. The transfection efficiency is maximal at DNA:cationic polymer = 1:0.5 and DNA 2 ㎍ for lentivirus production. Then, the lentiviral including 4-1BBL and OX40L was used to deliver CT26 mouse tumor cells to establish optimal delivery conditions according to the amount of virus. The transduction efficiency is maximal at 500 μL volume of lentiviral stock without change in cell shape or growth rate. CT26-4-1BBL, CT26-OX40L significantly inhibited the tumor growth compare with CT26-WT or CT26-β-gal cell line. These data showed the possibility the use of genetically modified tumor cells with costimulatory molecule as cancer immunotherapy agent.

• Structural Engineering and Mechanics
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• 제39권2호
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• pp.207-221
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• 2011

This paper aims to study the behavior of short reinforced concrete columns confined with external glass Fiber Reinforced Polymers (GFRP) sheets under eccentric loads. The experimental part of the study was achieved by testing 9 specimens under eccentric compression. Three eccentricity ratios corresponding to e/t = 0, 0.10, 0.50 in one direction of the column were used. Specimens were divided into three groups. The first group was the control one without confinement. The second group was fully wrapped with GFRP laminates before loading. The third group was wrapped under loading after reaching 75% of failure loads of the control specimens. The third group was investigated in order to represent the practical case of strengthening a loaded column with FRP laminates. All specimens were loaded until failure. The results show that GFRP laminates enhances both failure load and ductility response of eccentrically loaded column. Moreover, the study also illustrates the effect of confinement on the first crack load, lateral deformation, strain in reinforcement and failure pattern. Based on the analysis of the experimental results, a simple model has been proposed to predict the improvement of load carrying capacity under different eccentricity ratios. The predicted equation takes into consideration the eccentricity to cross section depth ratio, the ultimate strength of GFRP, the thickness of wrapping laminate, and the time of wrapping (before loading and under loading). A good correlation was obtained between experimental and analytical results.

• 약학회지
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• 제44권4호
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• pp.293-299
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• 2000

Biodegradable microspheres made from poly-lactide-co-glycolide polymers have been considered as a new delivery system for single-dose vaccine. Purified tetanus toxoid (TT) was encapsulated in poly-lactide(PLA) and poly-lactide-co-glycolide (PLGA) microparticles using a solvent evaporation method in a multiple emulsion system (water-in oil-in water). The morphology of 77-loaded microparticles was spherical and the suface of them was smooth. The particle size was in a range of 2-10. Protein loading efficiency was 68-97.8%. PLGA (85:15) microparticle showed the highest efficiency. Protein release pattern was influenced by polymer molecular weight and composition. The release rate of PLA(Mw 100,000) microsphere was higher than any other microspheres. In consequence of the hydrolysis of PLGA(50:50) microspheres, environmental pH decreased from 7.4 to 5.0. The PLA, PLGA (75:25) and PLGA (85:15) microshperes showed no significant pH change. The antigenicity or n in microshperes was assayed by indirect sandwich ELISA using equine polyclonal tetanus antitoxin for capture antibody and human polyclonal tetanus antitoxin for primary antibody. The antigenicity of TT in PLA (Mw 100,000), PLGA(50:50, Mw 100,000) and PLGA (75:25, Mw 73,300) after 30 days incubation showed 54, 40.9 and 76.7%, respectively.

• Journal of electromagnetic engineering and science
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• 제14권3호
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• pp.293-298
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• 2014

Large spaceborne antennas should be lightweight, a factor related to the development costs of launch vehicles. In order to overcome this drawback, a feasibility study of a new carbon fiber reinforced polymer (CFRP) named M55J/RS3 is carried out for a synthetic aperture radar (SAR) reflector antenna. In particular, the high resolution of detected images is taken into consideration. To validate the electrical performance, a test of the CFRP specimen is fabricated, and the transmission/reflection coefficients are measured using a standard X-band waveguide. Finally, the effective complex permittivity and effective electrical conductivity are derived from the obtained measured data. By applying the derived conductivity to the simulation of the radiation pattern, antenna gain, and beamwidth-instead of relying on the assumption of a perfect electric conductor-variations in electrical performance are also investigated and discussed.

• 조명전기설비학회논문지
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• 제13권4호
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• pp.68-74
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• 1999

본 연구는 고분자재료에서 음향센서를 이용한 부분방전의 음향적 탐지를 행했다. 저밀도 폴리에틸렌에 대한 트리잉파괴 실험에서 음향센서로 얻어진 음향방출 특성의 시간순서대로 측정하여 통계처리를 행했다. 또한 5가지 특성량을 도입하고 $\psi$-AEA-n(위상-음향진폭-펄스수) 패턴을 분석한 결과, 보이드 시료의 AE평균개시진폭 $(\overline{AEA_{inc}})$과 AE 평균최대진폭$(\overline{AEA_{max}})$은 열화중기, AE펄스수, AE평균최대위상각$(\overline{\theta{max}})$은 열화말기를 진단하기 위해서 유용한 음향방출량임을 알 수 있다. 이들 음향방출량은 보이드 시료의 열화진단을 구별하는데 유용한 음향방출량임을 실험결과로부터 얻었다.

• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2011년도 제45차 학술발표회
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• pp.44-44
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• 2011

본 연구에서는 직물조직의 분석과정을 자동화할 수 있는 전용 하드웨어 및 소프트웨어를 개발하였다. 직물조직의 분석은 직물 설계 및 품질관리 단계에서 매우 중요한 공정이나 현재까지도 확대경과 분해침에 의존하여 수작업으로 이루어지고 있는 것이 실정이라 자동화가 절실히 요구되는 분야라고 할 수 있다. 최근 컴퓨터 기술의 발달로 섬유산업 분야에서도 자동화 관련 연구가 많이 이루어지고 있으며 직물 분석 과정에 대한 연구도 여러 차례 시도된 바 있다. 여기에는 주로 디지털 영상으로부터 특징을 찾아내고 분석하는 이미지 프로세싱 기법이 쓰였는데 이는 재현성, 정확성, 속도 등에서 육안에 의한 방법과는 비교할 수 없는 장점을 가지고 있다. 그러나 기존의 연구들은 카메라의 한계로 인해 주로 저해상도의 이미지를 가지고 작업을 하거나, 이미지 프로세싱 또는 인공 신경망을 단독으로 적용하는 등의 한계를 가지고 있었다. 본 연구에서는 이러한 문제점을 극복하기 위해 초고해상도 직물 이미지를 획득한 뒤 이로부터 직물의 교차점을 인식하는데 필요한 파라미터를 추출하고 이를 인공 신경망에 학습시켜 직물 설계에 필요한 조직도를 생성하는 시스템을 개발하고자 하였다. 이를 위해 먼저 컴퓨터로 컨트롤이 가능한 직물 분석 전용 초정밀 XY 스테이지의 하드웨어를 설계 제작 하였으며 각종 이미지 분석 및 하드웨어 컨트롤에 필요한 전용 소프트웨어를 개발하였으며 그 결과 각종 직물의 조직을 매우 정확히 인식할 수 있게 되었다. 향후 이미지 획득 과정의 보완, 새로운 파라미터의 정의 및 신경망의 반복 학습을 통해 본 시스템이 보다 보완된다면 직물 분석 작업의 자동화를 통한 제품 개발과 생산에 소요되는 시간을 단축 및 품질 관리 공정의 자동화에 기여할 수 있을 것으로 기대된다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 Techno-Fair 및 추계학술대회 논문집 전기물성,응용부문
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• pp.100-101
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• 2007

Polymer thick film capacitors were successfully fabricated by using ink-jet printing and screen printing technology. First, a bottom electrode was patterned by ink-jet printing of a nano-sized silver ink. Next, a dielectric layer was formed by the screen printing, then a top electrode was pattern by ink-jet printing of a nano-sized silver ink. The printed area of the dielectric layers were changed into $2{\times}2m^2$and $4{\times}2m^2$, and also the area of the electrodes were patterned with $1{\times}1mm^2$ and $1{\times}3mm^2$. The thickness of the printed dielectric layer was ranged from 1.1 to $1.4{\mu}m$. The analysis of capacitances verified that the capacitances was proportional to the area of the printed electrode. The capacitances of the fabricated capacitors resulted in one third of the calculated capacitances.

• 한국전기전자재료학회논문지
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• 제24권10호
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• pp.790-793
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• 2011

In this study, the surface modification for a silicon(Si) mold using $CHF_3$ inductively coupled plasma(ICP). The conditions under that plasma was treated a input ICP power 600 W, an operating gas pressure of 10 mTorr and plasma exposure time of 30 sec. The Si mold surface became hydrophobic after plasma treatment in order to $CF_x$(X= 1,2,3) polymer. However, as the de-molding process repeated, it was investigated that the contact angle of Si surface was decreased. So, we attempted to investigate the degradation mechanism of the accurate pattern transfer with increasing the count of the de-molding process using scanning electron microscope (SEM), contact angle, and x-ray photoelectron spectroscopy (XPS) analysis of Si mold surface.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 추계학술대회 논문집
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• pp.698-701
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• 2005

We have investigated experimentally a nano patterning using electron beam lithography for the nickel stamper fabrication. Recently, DVD and Blu-ray disk(BD) have nano-scale patterns in order to increase the storage density. Specially, BD has 100nm-scale patterns which are generally fabricated by electron beam lithography. In this paper, we found optimum condition of electron-beam lithography for 100nm-scale patterning. We controlled various conditions of EHP(acceleration voltage), beam current, dose and aperture size in order to obtain optimum conditions. We used 100nm-thick PMMA layer on a silicon wafer as photoresist. We found that EHP was the most dominant factor in electron-beam lithography.