• Korean Journal of Veterinary Research
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• v.34 no.4
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• pp.727-734
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• 1994

To elucidate the effect of calcitonin gene-related peptide(CGRP), vasoactive intestinal peptide(VIP) and substance P was investigated with perivascular nerve stimulation and treatment of peptides from polygraph in the isolated renal artery of rabbit. 1. The neurogenic contraction induced by perivascular nerve stimulation was the frequency-dependent manner(264 Hz) in the isolated renal artery of rabbit. 2. CGRP and VIP caused the relaxation on the precontraction with noradrenaline($10{\mu}m$) on the presence and absence of endothelium in the isolated renal artery of rabbit. 3. Substance P caused the endothelium-dependent relaxation on the precontraction with noradrenaline($10{\mu}m$) in the isolated renal artery of rabbit. 4. CGRP and VIP inhibited the neurogenic contraction by the perivascular nerve stimulation(0.3 ms, 80 V, 50 Hz, 1 sec) on the absence and presence of endothelium in the isolated renal artery of rabbit. 5. Substance P inhibited on the neurogenic contraction by the perivascular nerve stimulation with the endothelium-dependent in the isolated renal artery of rabbit.

• The Journal of Korean Medicine
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• v.25 no.1
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• pp.60-71
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• 2004

Objectives : We have examined the relaxational response to the water extract of genus Panax in rat thoracic aorta and mesenteric artery. Methods : Segments of thoracic aorta and mesenteric artery obtained from rats immediately after delivery were mounted in organ baths superfused on a polygraph. Results : We found that the thoracic aorta segments responded to the water extract of genus Panax with a dose-dependent vasorelaxation. At $10^{-5}m$ 5-hydroxytrptamine (5-HT), the maximal contraction force were 94.9% of the maximum KCl-response. At $10^{-5}m$ 5-HT - induced contraction, The contractile response of thoracic aortic rings were inhibited by 54.7%, 36.3% and 31.3% after addition of the high concentration (100 mg/ml) of water extract of Panax ginseng, Panax japonicus and Panax quinquefolium. The contractile response of mesenteric arteries were inhibited by 88.3%, 87.7%, and 70.3% after addition of the high concentration (100 mg/ml) of water extract of Panax ginseng, Panax japonicus and Panax quinquefolium. Conclusions : In conclusion, water extract of genus Panax - induced relaxation in the isolated rat thoracic aorta and mesenteric artery were composed of endothelium - independent relaxation and dose - dependent relaxation.

• Journal of Preventive Medicine and Public Health
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• v.17 no.1
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• pp.239-243
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• 1984

The vascular reaction such as the indirect blood pressure and the pulse rate of the tail to the noise were examined in 8 naive Sprague-Dawley rats of both sexes. The sounds used in the experiment were 1KHz and 4 KHz, 95dB pure tone generated by Nagashima Audiometry. The indirect blood pressure and the pulse rate were checked at the rat tail by Polygraph at 5 minutes interval. The results were as follows: 1. The blood pressure and the pulse rate increased maximally 5 minutes after the exposure to both sounds. 2. The blood pressure and the pulse rate returned normal range within 20 minutes after the exposure of both sounds. 3. The increment of the blood pressure and the pulse rate was greater after the sound of 4KHz than after that of 1KHz, but it wasn't statistically significant.

• The Korean Journal of Pharmacology
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• v.16 no.1 s.26
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• pp.35-39
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• 1980

In this study, the effects of phenoxybenzamine and related drugs on the action of CCK-PZ and caerulein were examined in isolated gall bladder of guinea pig and higher esophagus strip of fowl. The strips were placed in a bath containing Locke-Ringer solution maintained at $38^{\circ}C$. Oxygen was continuously bubbled through the solution. The contractile response was measured isometrically by a force displacement transducer connected to polygraph. In isolated gall bladder preparation caerulein produced contractile response of CCK-PZ type, but the relative potency on a weight basis was 30 times stronger than CCK-PZ. The response of caerulein or CCK-PZ was not blocked by cholinergic blocking agent and both alpha and beta adrenergic blockades, however, the response of caerulein or CCK-PZ was exceptionally blocked by phenoxybenzamine. In isolated esophagus strip CCK-PZ with high concentration produced marked contraction which was not modified by atropine and other blocking agents, whereas the response was blocked by phenoxybenzamine. These results lead to the conclusion that phenoxybenzamine inherently inhibits the contractile response of CCK-PZ and caerulein on esophagus and other smooth muscle.

• The Korean Journal of Pharmacology
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• v.11 no.1 s.17
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• pp.15-18
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• 1975

The effect of skin extracts of Korean amphibian, poisonous snake and fresh-water fish were determined for their caerulein-like action on rabbit gall bladder strips. The isolated gall bladder strips were prepared according to the technique described by Amer and Becvar(1969). The strips were placed in a bath containing 100ml of Locke-Ringer solution maintained at $38^{\circ}C$. Oxygen was continuously bubbled through the solution. The tension of the muscle strip was initially adjusted to 0.7g. The contractile response was measured isometrically by a force-displacement transducer connected to a polygraph. In this rabbit gall bladder strip caerulein produced contraction of CCK-PZ type. The skin extract of Korean amphibian also elicited similar contraction as caerulein, which extracted from Australian amphibian, Hyla caerulea, by Erspamer et al. The calculated amount was approximately $2{\mu}g$ caerulein per gram of skin tissue in Korean amphibian and the potency was about 1/200 of that seen in Australian amphibian. The contraction of gall bladder strip by our amphibians occurs in decreasing order; Rana Nigromaculata coreana Okada, Rana nigromaculata Hallowell, Hyla arborea japonica Gunther and Bombina orientalis Boulenger. The skin extracts of poisonous snake and fresh-water fish produced no caerulein-like activity.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.20 no.12
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• pp.808-813
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• 2008

The study was to evaluate the air-conditioning of sleep algorithm. The algorithm was developed through the analysis of brain waves and MST, the experiments using air conditioner was performed in a apartment bedroom. Five female subjects were participated for the experiment. Eight hours of data collection a day was performed under different algorithm, case A, case B and case C. Physiological signals, EEG, ECG, EOG, and EMG, were obtained using polygraph and converted into digital signal. Then, subjects were asked to answer the questionnaire about their thermal sensation after experiment in bedroom. Sleep stages were classified, then TST, Sleep latency and Sleep efficiency were calculated for the three different air conditioner algorithm. As results, TST, Sleep efficiency, questionnaire showed the higher values for Case B algorism than that for other algorism. On the other hand, SWS latency was lower than for other conditions. Therefore, it was concluded that Case B of the algorithm was the best for comfortable and deep sleep.

• Journal of the korean academy of Pediatric Dentistry
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• v.1 no.1
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• pp.49-55
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• 1974

Electromyographic studies were performed on the action of the masseter muscles. Among the children aged from 6 to 8 years, ten children with normal occlusion and another ten with space maintainer were selected. The children were divided into 3 groups. They were: 1) A group: Children who removed space maintainer 2) B group: Children who inserted space maintainer 3) C group: Children with normal occlusion. The electromyogram was recorded with 4 channel polygraph. (Grass model VII) Electrodes which were cup-typed gold disks, 9 millimeters in the diameter, were located on the superficial layer of masseter muscles. The electromyogram was recorded in the physiologic rest position, molar occlusion, chewing movement, protraction, left lateral movement, and right lateral movement. The conclusions were as follows. 1. In the physiologic rest position, lateral movement, the electrical potentials of the masseter muscles were not changed clearly in each groups. 2. In molar occlusion, chewing movement, The electrical potentials of the masseter muscles of the B group were almost 10% higher than those of A group, and were almost 60-70% in comparision with C group. 3. In protraction, the electrical potentials of the masseter muscles of the B group were almost 40% higher than those of A group, and were almost equal to C group. 4. The electrical activities of the masseter muscles in the mandibular movements were in the following order: (1) Molar occlusion (2) Chewing movement (3) Protraction (4) Lateral movement.

• Journal of the Korean Society of Clothing and Textiles
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• v.44 no.5
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• pp.824-836
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• 2020

This study investigated the effects of textile attachments on electroencephalogram using 20 persons (10 males and 10 females). Four types of attachment cushions were manufactured by changing the shell fabric (cotton and microfiber) and interlining (synthetic loose fiber and buckwheat). This was done using BIOS-S8 (BioBrain Inc., Korea), an 8-channel polygraph for multi-body signal measurement, to measure EEG. Data were analyzed using the SPSS 24.0 statistical program. EEG values were significantly activated according to gender, particularly when the subjects' eyes were open. For the male cases, 'RT', 'RAHB' values were highly activated and for the female cases, 'RA', 'RB', 'RG', 'RFA', 'RST', 'RLB', 'RMB', 'RST', 'RMT' values were highly activated. Examining the differences in EEG according to type of attachment indicated no significant difference in both sexes. However, in cases of females with their eyes closed, the 'RSA' index was quite different in the left occipital lobe (O1), and when their eyes were open, the 'RFA' in the right frontal lobe (F4) showed a significant difference. However, there was no obvious correlation between the activation of EEG and the subjective preference of textile attachments.

• The Korean Journal of Pharmacology
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• v.16 no.2 s.27
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• pp.25-29
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• 1980

Etomidoline ($Nonspa^{\circledR}$), which is chemically related to tertiary amine, is new synthetic antispasmodic agent with analgesic action. Antispasmodic effect of this agent is stronger than hyoscine butylbromide ($Buscopan^{\circledR}$), quaternary amine, and the absorption from intestine is also much higher. This study was undertaken to determine the effect of etomidoline on duodenal motility and other smooth muscles of rabbit. Strips of various isolated smooth muscle, 2 cm long from adult rabbits weighting about 2 kg, were suspended in a muscle chamber containing Tyrode's solution, which was bubbled with oxygen gas, and the temperature of the solution was kept constant at $38^{\circ}C$. After being washed with fresh solution several times the strips of smooth muscle attained constant motility and tonus. Etomidoline and other drugs were added in various concentrations to the chamber. Contractility of the strips was measured by using polygraph (Grass, model 7). The results are as follows: 1) In isolated rabbit atrium etomidoline produces a slight depression of contractility and the rate is also decreased. 2) On the other hand, etomidoline relaxed isolated strips of stomach, duodenal, and detrusor of rabbit. This relaxing effect of etomidoline on isolated duodenal strip of rabbit was not blocked by ${\alpha}$-adrenergic blocking agent, phenoxybenzamine, but by ${\beta}$-adrenergic blocking agent, propranolol. 3) Etomidoline did not exert any effect on isolated aorta, gall bladder, and trigone of rabbit. From the above results, it may be concluded that the relaxing effect of etomidoline on duodenal strip is related ${\beta}$-adrenergic receptor.

• Journal of Chest Surgery
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• v.17 no.1
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• pp.101-109
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• 1984

The influences of acute respiratory and metabolic acid-base disturbances on the carotid, renal and coronary blood flow were measured in dogs. Respiratory acidosis was induced by artificial respiration with 8% CO2 -02 gas mixture and respiratory alkalosis was induced by hyperventilation under the control of respirator. Metabolic acidosis and metabolic alkalosis were induced by intravenous infusion of 0.3N hydrochloric acid and 0.6M sodium bicarbonate solution. To observe the effect of hyperkalemia, isotonic potassium chloride solution was infused. CVI electromagnetic flowmeter probes were placed on the left common carotid artery, left renal artery and left circumflex coronary artery. Each flow was recorded on polygraph. 1. The carotid blood flow showed rapid showed rapid and marked increase in acute respiratory acidosis. Even in the cases when arterial blood pressure was lowered during the state of respiratory acidosis, carotid blood flow increased. By the infusion of hydrochloric acid, carotid blood flow increased slowly and returned to the previous label after discontinuation of the infusion. Carotid blood flow also increased by the infusion of large amount of sodium bicarbonate, but it might be the combined effect of expansion of extracellular fluid and compensatory elevation of carbon dioxide tension. 2.The renal blood flow remained unchanged during the acute acid-base disturbances, suggesting effective autoregulation. Renal blood flow, however, increased very slowly when the infusion of potassium chloride continued for a long period. 3.Although less marked than the carotid blood flow, the coronary blood flow increased in the acute respiratory and metabolic acidosis. In asphyxiated condition, coronary blood flow increased most markedly and this might be the combined effect of hypoxia, hypercapnea, and lowering of pH. In summary, the carotid blowflow showed more marked change in the acute respiratory and metabolic acidosis than the renal and coronary blood flow. Respiratory and metabolic components of acid-base disturbances may influence the local blood flow concomitantly, there being more differences in the individual responses, but respiratory component manifested more rapid and marked effect than metabolic component.