• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4303-4310
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• 2015

Rumex vesicarius is an edible herb distributed in Egypt and Saudi Arabia. The whole plant has significant value in folk medicine and it has been used to alleviate several diseases. Hepatocellular carcinoma (HCC), the major primary malignant tumor of the liver, is one of the most life-threatening human cancers. The goal of the current study was to explore the potent role of Rumex vesicarius extract against HCC induced in rats. Thirty adult male albino rats were divided into 3 groups: (I): Healthy animals received orally 0.9 % normal saline and served as negative control group, (II): HCC group in which rats were orally administered N-nitrosodiethylamine NDEA, (III): HCC group treated orally with R. vesicarius extract in a dose of 400 mg/kg b.wt daily for two months. ALT and AST, ALP and ${\gamma}$-GT activities were estimated. CEA, AFP, AFU, GPC-3, Gp-73 and VEGF levels were quantified. Histopathological examination of liver tissue sections was also carried out. The results of the current study showed that the treatment of the HCC group with R. vesicarius extract reversed the significant increase in liver enzymes activity, CEA, AFP, AFU, glypican 3, golgi 73 and VEGF levels in serum as compared to HCC-untreated counterparts. In addition, the favorable impact of R. vesicarius treatment was evidenced by the marked improvement in the histopathological features of the liver of the treated group. In conclusion, the present experimental setting provided evidence for the significance of R. vesicarius as anticancer candidate with a promising anticancer potential against HCC. The powerful hepatoprotective properties, the potent antiangiogenic activity and the effective antiproliferative capacity are responsible for the anticancer effect of this plant.

• 한국한의학연구원논문집
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• 제13권3호
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• pp.157-163
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• 2007

Objective: Polygonum multiflorum Thunberg (Polygonaceae) has been traditionally used as a tonic and the purgative in China and Korea. The genus Polygonum is a source of a wide range of phenolic compound, flavanoids, anthraquinones, stilbenes and tannins. In this study, three anthraquinones were isolated and quantitative determination of anthraquinones from P multiflorum has been developed for quality standardization. Methods : Three anthraquinone derivatives were isolated from a methanol extract of the radix of P. multiflorum by the chromatographic separation. Their structures were identified as emodin, physcion and ${\omega}$-hydroxyemodin on the basis of spectral data (MS, lH-NMR, 13C-NMR) and chemical analysis. HPLC analysis was performed to determine the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin in P. multiflorum from different specimens were collected from twenty Korean markets. Results: According to the results, the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin were 0.145%, 0.434%, 0.016%, 0.026%, 0.030% by HPLC, respectively. Conclusions : In these results, we have determined the contents of emodin, physcion, chrysophanol, rhein and ${\omega}$-hydroxyemodin in P. multiflorum, respectively. We hope that this study will contribute to the standardization and quality control of herbal medicine.

• 한국환경복원기술학회지
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• 제12권6호
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• pp.153-163
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• 2009

This study was carried out to offer ecological restoration plan of local streams by analyzing the vegetation and flora around four local streams (Pungchoncheon, Namchangcheon, Ganggicheon, Woncheoncheon) in Namwon. Flora and vegetation investigation was done at April 2007 to August 2007, and June 2009. The 194 of vascular plants were identified which contain 53 families, 143 genera, 194 species. The Family frequencies arranged by the order of Family Compositae (14.4%), Family Gramineae (13.4%) Family Leguminosae (6.7%) and Family Polygonaceae (5.2%). The naturalized plants were listed as 33 species, and their naturalization ratio and urban index were found to be 17.0%, and 12.2%, respectively. In this study a total of 21 relev$\acute{e}$s collected and analyzed. 6 plant communities are differentiated : Riverine softwood forests (Phragmites japonica-Salix gracilistyla community), Perennial herb vegetations on lotic water zone (Phragmites japonica community, Phalaris arundinacea community), Perennial herb vegetations on lentic water zone (Persicaria thunbergii-Typha orientalis community, Phragmites communis community), Annual or biennial vegetations on waterside (Persicaria thunbergii community). Species showing the higer value in the plant communities were Persicaria thunbergii, Phragmites japonica, Artemisia princeps, Humulus scandens, Bidens frondosa, Oenanthe javanica, Agropyron tsukusinense var. transiens, Stellaria aquatica, and Lactuca indica var. laciniata.

• 한국잡초학회지
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• 제13권2호
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• pp.164-172
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• 1993

1992년(年) 6월(月)과 9월(月)에 경북지방(慶北地方)의 묘지에 분포하는 잡초(雜草)를 조사하여 얻어진 결과는 다음과 같다. 1. 묘지에서 조사된 잡초종(雜草種)은 53과 196종으로 그 중 일년생(一年生) 31종, 울년생(越年生) 38종, 다년생(多年生) 127종이었다. 2. 묘지에서 조사된 잡초종(雜草種)을 과별(科別)로 보면 국화과 34종, 벼과 27종, 콩과 17종, 장미과 10종, 백합 미나리아재비과 8종, 석죽 배추과 7종, 꿀풀 마디풀과 6종, 돌나물 사초과 4종 그리고 나머지 41과에서 1~3종의 잡초(雜草)가 조사되었다. 3. 경북지방(慶北地方)의 묘지에서 우점(優占)하는 초종은 띠, 쑥, 제비꽃, 개망초, 망초, 산딸기, 꿀풀 등이었다.

• 대한한의학회지
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• 제20권3호
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• pp.87-93
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• 1999

Objectives: This study was conducted to analyze scientifically the purgative action of Chungpesagan-tang, which was widely used for stroke In Oriental Medicine. Methods: The contents of sennoside A on the water-extraction of Rhei Rhizoma, the transforming activity of sennoside A to rheinanthrone by human intestinal bacteria, and the anti-costive activity of Chungpesagan-tang, Rhei Rhizoma and Yuldahanso-tang on mice were investigated. Results: Rhei Rhizoma (Rheum palmatum, from China) had dose-dependent potent purgative action. Chungpesagan-tang containing this Rhei Rhizoma had more potent purgative action than Rhei Rhizoma only. However, Korean cultivated Rhei Rhizoma (Rheum undulatum) and Chungpesagan-tang containing this Korean cultivated Rhei Rhizoma had no purgative action. Conclusions: These results suggest that Chungpesagan-tang polyprescription should be considered to enhance the purgative action of Rhei Rhizoma.

• 한국환경생태학회지
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• 제21권1호
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• pp.1-12
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• 2007

울릉도 식물상의 참고문헌과 야외조사를 통해 확인된 귀화식물은 21과 49속 63종 2변종 65분류군이며, 국화과 27.7%, 벼과, 콩과, 마디풀과 각각 7.7%로 확인되었다. 본 연구를 통하여 좀소리쟁이, 노랑토끼풀, 덩이괭이밥, 유럽전호, 둥근잎나팔꽃, 큰금계국, 별꽃아재비, 몬트부레치아, 큰김의틸 총 9종이 추가 확인되었다. 1년생 초본류는 36.9%이고, 유럽 원산지가 40.0%를 차지하였다. 울릉도의 도시화지수는 22.0이며, 각각의 참고문헌에 의하면 귀화율은 증가하고 있는 것으로 확인되었다. 울릉도의 생태계 교란 야생식물로는 돼지풀이 생육하고 있었다. 귀화식물의 관리방안으로는 원예용 식물 유입의 최소화 및 확산 방지와 절개지 복구용으로 자생종을 활용하여 천이를 유도하는 것이 필요하다.

• 한국자원식물학회지
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• 제24권6호
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• pp.702-711
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• 2011

Buckwheat (Fagopyrum esculentum Moench), one of the minor crops grown in Korea belonging to the Polygonaceae family, is an annual crop widely cultivated in Asia, Europe, and America and has a character of outcrossing and self-incompatibility. The objective of this study was to analyze the genetic variability, phylogenetic relationships and population structure of buckwheat landraces of Korea using SSR markers. Ten microsatellite markers have been detected from a total of 79 alleles among the 179 buckwheat accessions were collected from Korea. The number of allele per marker locus ($N_A$) ranged from 2 (GB-FE-001, GB-FE-043 and GB-FE-055) to 31 (GB-FE-035) with an average of 7.9 alleles. GB-FE-035 was the most polymorphic with the highest PIC value 0.93. Major allele frequencies ($M_{AF}$) for the 10 polymorphic loci varied from 0.12 to 0.97 with a mean allele frequency of 0.57. The expected heterozygosity ($H_E$) values ranged from 0.05 to 0.94 with an average of 0.53. The observed heterozygosity ($H_O$) ranged from 0.06 to 0.92 with an average of 0.42. The overall polymorphic information contents (PIC) values ranged from 0.05 to 0.93 with an average of 0.48. The landrace accessions of buckwheat used in the present study were not distinctly grouped according to geographic distribution. The study concludes that the results revealed genetic differentiation was low according to the geographic region because of outcrossing and self-incompatibility. We reported that our analyses on the genetic diversity of common buckwheat cultivars of Korea were performed by using of microsatellite markers.

• 대한본초학회지
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• 제30권6호
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• pp.17-24
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• 2015

Objectives : Persicaria tinctoria belongs to the Polygonaceae family and it has been used as the natural dye traditionally. Also, it is well known that the Persicaria tinctoria is used for treating the following symptoms such as fever, inflammation and edema. The purpose of this study is to investigate the effective source of antioxidants and anti-inflammatory agent from various parts of Persicaria tinctoria.Methods : We investigated the antioxidative and anti-inflammatory properties of the Persicaria tinctoria extracts. Antioxidant activities were measured by 1,1-diphenyl-2- picrylhydrazyl (DPPH), 2, 2'-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity, Fe²⁺ chelating activity and Reducing power of Persicaria tinctoria extracts. And its inhibitory effect against oxidative DNA damage was evaluated in non-cellular system using φX-174 RF I plasmin DNA. The anti-inflammatory effect of Persicaria tinctoria was measured by using the inhibitory efficacy for the amount of nitric-oxide (NO) produced in LPS induced RAW264.7 cells.Results : The extracts from stem part showed better DPPH scavenging activity compared to those of the leaf and root extracts. Their IC₅₀s were measured as 7.17, 144.40 and 165.07 ug/ml, respectively. These results were similar to that of ABTS radical scavenging assay and reducing power. Also, Persicaria tinctoria showed the protective effects of DNA damage against oxidative stress and anti-inflammatory effect by suppression of NO production in LPS induced RAW264.7 cells.Conclusions : These results showed that various parts of Persicaria tinctoria can be used as an effective source of antioxidants and anti-inflammatory agents via antioxidative activities and anti-inflammatory effect.

• 식물분류학회지
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• 제48권3호
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• pp.185-194
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• 2018

A comparative floral morphological study of 19 taxa in Persicaria sect. Cephalophilon with four taxa related to Koenigia was conducted to evaluate the taxonomic implications. The flowers of P. sect. Cephalophilon have (four-)five-lobed tepals; five, six, or eight stamens, and one pistil with two or three styles. The size range of each floral characteristic varies according to the taxa; generally P. humilis, P. glacialis var. glacialis and Koenigia taxa have rather small floral sizes. The connate degrees of the tepal lobes and styles also vary. The tepal epidermis consists of elongated rectangular cells with variation of the anticlinal cell walls (ACWs). Two types of glandular trichomes are found. The peltate glandular trichome (PT) was observed in nearly all of the studied taxa. The PT was consistently distributed on the outer tepal of P. sect. Cephalophilon, while Koenigia taxa and P. glacialis var. glacialis had this type of trichome on both sides of the tepal. P. criopolitana had only long-stalked pilate-glandular trichomes (LT) on the outer tepal. The nectary is distributed on the basal part of the inner tepal, with three possible shapes: dome-like, elongated, and disc-like nectary. The nectaries are always accompanied by elongated or spheroidal papillae. Various combinations of floral characters (e.g., the numbers of stamens and styles, the stigma shape, the nectary shape, ACWs, cuticular striation and the trichome type and distribution) of P. sect. Cephalophilon are useful when attempting to recognize the infrasectional levels of P. sect. Cephalophilon recently proposed. Here, we describe the floral characteristics in detail and discuss the taxonomic significance of the floral characters.

• 약학회지
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• 제50권6호
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• pp.351-357
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• 2006

Polygoni Radix (Polygonaceae) has been used as renal disoder hematopoietic, menstrual irregularity and antiaging in Korean folk medicine. Specially aerial parts has been used for insomnia and sedative agent. In order to investigate the efficacy of antioxidant activity on these aerial parts, the bio-activity guided fraction and isolation of physiologically active substance were performed. H$_2$O, 30%, 60%, 100% MeOH were examined antioxidant activity by DPPH method. It was revealed that 30%, 60% MeOH fractions have significantly antioxidant activity. From 60% MeOH fraction, six known flavonoid glycosides (quercetin, quercetin 3-O-${\beta}$-D-galactopyranosyl-4'-O-glucopyrano side-3'-methyl ether, quercetin 3-O-${\alpha}$-L-rhannopyranoside, quercetin 3-O- ${\alpha}$-L-rhamnopyranoside-4'-methylethor, quorcetin 3-O-${\beta}$-D-galactopyranoside, quercetin 3-O-${\beta}$-D-galactopyranoside) and 3,4-Oihydrocinnarnic acid were isolated. To investigate the antioxidant activities of each com-pounds, we measured radical scavening activity with DPPH method and anti-lipid peroxidative efficacy on low density lipo-protein (LDL) with TBARS assay and anti-acetylcholinestrase activity with Ellman's Test. Four compounds (ll, IV Vl, Vll) of quercetin glycosides showed significant activity.