• 제목/요약/키워드: poly paper

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Analysis of the relationship between the end weight trait and the gene ADGRL2 in purebred landrace pigs using a Genome-wide association study

  • Kang, Ho-Chan;Kim, Hee-Sung;Lee, Jae-Bong;Yoo, Chae-Kung;Choi, Tae-Jeong;Lim, Hyun-Tae
    • Korean Journal of Agricultural Science
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    • v.45 no.2
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    • pp.238-247
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    • 2018
  • The overall consumption of meat is increasing as the level of national income increases. The end weight is a trait closely associated with dressed meat. Genome-wide association study (GWAS) is an effective method of analyzing genetic variation and gene identification associated with a number of natural alternative traits because it can detect variations. So this paper did a GWAS analysis to identity the location on the genome related to the end weight in purebred landrace pigs and to explore the relevant candidate gene. This study identified a significant single nucleotide poly morphism (SNP) marker in chromosome 6 (ASGA0029422, $p=1.22{\times}10^{-6}$). Adhesion G protein-coupled receptor L2 (ADGRL2) was found to be the candidate gene at the identified SNP marker location. ADGRL2 genes have been found to be associated with cell development in relation to the external and internal environment of a cell. In addition, genotype and statistical analyses were done on nine variations on the exon of ADGRL2. The results show that the SNP marker (ASGA0029422, $p=1.32{\times}10^{-6}$) was significant, but the significance of the nine variations on the ADGRL2 exon was not verified. However, by performing further experiments and functional studies on other SNPs showing possible genetic ADGRL-Exon mutations, objects with high associations of high-end weights can be selected.

High Frequency Scattering from Cylindrical Scatterer (원통형 산란체의 고주파 산란 특성)

  • Kim Kitaek;Yoon Kwan-Seob;La Hyoungsul;Na Jungyul
    • The Journal of the Acoustical Society of Korea
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    • v.24 no.8
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    • pp.441-446
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    • 2005
  • This paper presents the changes of acoustic scattering pattern from a single cylinder and two identical cylinders in both theoretical calculations and experimental measurements. Bi-static scattering pattern by single cylinder and two parallel cylinders (length 2m, radius 30mm) was measured in $5m\times5m\times5m$ water tank using high frequency projector (120 kHz) and hydrophone. The results show similar agreement between experiment and theory. In case of single cylinder scattering. omni-directional pattern was observed in backward but there are fluctuations or target strength in forward. Interference between each cylinder's scattering fields produce fluctuations of target strength in all directions of two cylinders.

Regulated Drain Detection and Its Differential PLL Application to Compensate Processes (드레인 정규화 감지회로를 이용한 차동 PLL 설계 및 차동 공정보상기법)

  • Suh, Benjamin;Cho, Hyun-Mook
    • Journal of IKEEE
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    • v.9 no.1 s.16
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    • pp.40-46
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    • 2005
  • A process variation compensation method called 'regulated drain detection' is proposed. This paper also shows the how this newly invented method is applied to a typical differential PLL. The proposed RDD(regulated drain detection) and its PLL application has been designed and tested in a $0.18{\mu}m$ 1-poly 3-metal plain digital process so that its stable performance and higher yield can be proven. The implemented PLL aimed to the operation range of 80MHz - 240MHz and the total die size is only $0.18{\mu}m$ including the internal loop filter. The tracking jitter characteristics is measured to less than 150 peak-to-peak under l.8V supply rail.

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Loop Filter Voltage Variation Compensated PLL with Charge Pump (전하펌프를 이용한 루프 필터 전압변화 보상 위상고정루프)

  • An, Seong-Jin;Choi, Yong-shig
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.10
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    • pp.1935-1940
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    • 2016
  • This paper proposes a phase-locked loop (PLL) to minimize the loop filter output voltage fluctuation by using a comparator including RC time constant circuits. The voltage variation of loop filter is inputted to RC time constant circuits which have two RC time constants, large and small. While a small RC time constant circuit quickly conveys the output voltage variation of loop filter, a large RC time constant circuit conveys slowly the output voltage variation of loop filter and its output looks like constant voltage. The output signal of the comparator controls the sub charge pump and reduces the input voltage variation of voltage-controlled oscillator (VCO). Therefore, the proposed PLL generates a phase noise reduced signal. It has been designed with a 1.8V supply voltage, 0.18um multi - metal and multi - poly layer CMOS process and proved by Hspice simulation.

The Low Area 12-bit SAR ADC (저면적 12비트 연속 근사형 레지스터 아날로그-디지털 변환기)

  • Sung, Myeong-U;Choi, Geun-Ho;Kim, Shin-Gon;Rastegar, Habib;Tall, Abu Abdoulaye;Kurbanov, Murod;Choi, Seung-Woo;Pushpalatha, Chandrasekar;Ryu, Jee-Youl;Noh, Seok-Ho;Kil, Keun-Pil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.861-862
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    • 2015
  • In this paper we present a low area 12-bit SAR ADC (Successive Approximation Register Analog-to-Digital Converter). The proposed circuit is fabricated using Magnachip/SK Hynix 1-Poly 6-Metal $0.18-{\mu}m$ CMOS process, and it is powered by a 1.8-V supply. Total chip area is reduced by replacing the MIM capacitors with MOS capacitors instead of the capacitors consisting of overall part in chip area. The proposed circuit showed improved power dissipation of 1.9mW, and chip area of $0.45mm^2$ as compared to conventional research results at the power supply of 1.8V. The designed circuit also showed high SNDR (Signal-to-Noise Distortion Ratio) of 70.51dB, and excellent effective number of bits of 11.4bits.

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Vector Data Hashing Using Line Curve Curvature (라인 곡선 곡률 기반의 벡터 데이터 해싱)

  • Lee, Suk-Hwan;Kwon, Ki-Ryong
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.2C
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    • pp.65-77
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    • 2011
  • With the rapid expansion of application fields of vector data model such as CAD design drawing and GIS digital map, the security technique for vector data model has been issued. This paper presents the vector data hashing for the authentication and copy protection of vector data model. The proposed hashing groups polylines in main layers of a vector data model and generates the group coefficients by the line curve curvatures of the first and second type of all poly lines. Then we calculate the feature coefficients by projecting the group coefficients onto the random pattern and generate finally the binary hash from the binarization of the feature coefficients. From experimental results using a number of CAD drawings and GIS digital maps, we verified that the proposed hashing has the robustness against various attacks and the uniqueness and security by the random key.

Injectable TGF-beta 3-conjugated hyaluronic acid hydrogel for cartilage regeneration

  • Ko, Ki Seong;Lee, Jung Seok;Park, Kyung Min;Lee, Yunki;Oh, Dong Hwan;Son, Joo Young;Kwon, Oh Hee;Eom, Min Yong;Park, Ki Dong
    • Biomaterials and Biomechanics in Bioengineering
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    • v.2 no.1
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    • pp.23-32
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    • 2015
  • Facile immobilization of growth factors in hyaluronic acid (HA) hydrogels using dual enzymes is reported in the paper. The hydrogels were formed by using horseradish peroxidase (HRP) and hydrogen peroxide ($H_2O_2$) and transforming growth factor-${\beta}3$ (TGF-${\beta}3$) was covalently conjugated on the hydrogels in situ using tyrosinase (Ty) without any modifications. For the preparation of hydrogels, HA was grafted with poly(ethylene glycol) (PEG), which was modified with a tyrosine. The gelation times of the HA hydrogels were ranging from 415 to 17 s and the storage moduli was dependent on the concentration of $H_2O_2$ and Ty (470-1600 Pa). A native TGF-${\beta}3$ (200 ng/mL) was readily encapsulated in the HA hydrogels and 17% of the TGF-${\beta}3$ was released over 1 month at the Ty concentration of 0.5 KU/mL, while the release was faster when 0.3 KU/mL of Ty was used for the encapsulation (27%). It can be suggested that the growth factors resident in the hydrogels for a long period of time may lead cells proliferating and differentiating, whereas the growth factors that are initially released from the hydrogels can induce the ingrowth of cells into the matrices. Therefore, the dual enzymatic methods as facile gel forming and loading of various native growth factors or therapeutic proteins could be highly promising for tissue regenerative medicines.

Integrated Circuit Implementation and Characteristic Analysis of a CMOS Chaotic Neuron for Chaotic Neural Networks (카오스 신경망을 위한 CMOS 혼돈 뉴런의 집적회로 구현 및 특성 해석)

  • Song, Han-Jeong;Gwak, Gye-Dal
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.37 no.5
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    • pp.45-53
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    • 2000
  • This paper presents an analysis of the dynamical behavor in the chaotic neuron fabricated using 0.8${\mu}{\textrm}{m}$ single poly CMOS technology. An approximated empirical equation models for the sigmoid output function and chaos generative block of the chaotic neuron are extracted from the measurement data. Then the dynamical responses of the chaotic neuron such as biurcation diagram, frequency responses, Lyapunov exponent, and average firing rate are calculated with numerical analysis. In addition, we construct the chaotic neural networks which are composed of two chaotic neurons with four synapses and obtain bifurcation diagram according to synaptic weight variation. And results of experiments in the single chaotic neuron and chaotic neural networks by two neurons with the $\pm$2.5V power supply and sampling clock frequency of 10KHz are shown and compared with the simulated results.

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A Study on Combustion Characteristic with the Variation of Oxidizer phase in Hybrid Rocket Motor using PE/$N_2O$ (PE/$N_2O$ 하이브리드 로켓에서의 산화제 상 변화에 따른 연소특성 연구)

  • Lee, Jung-Pyo;Kim, Gi-Hun;Kim, Soo-Jong;Kim, Hak-Chul;Moon, Hee-Jang;Sung, Hong-Gye;Kim, Jin-Kon
    • Journal of the Korean Society of Propulsion Engineers
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    • v.14 no.2
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    • pp.46-53
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    • 2010
  • The purpose of this paper is to study combustion characteristics with the different phase of oxidizer in hybrid rocket combustion. HDPE(High Density Polyethylene) as fuel and $GN_2O$(Gas $N_2O$), $LN_2O$(Liquid $N_2O$) as oxidizer were used to perform the experiments. An investigation was performed for a change of the regression rate, pressure of combustion chamber and combustion efficiency according to the variation of oxidizer phase. In case of using $LN_2O$ as oxidizer, the regression rate is not significantly different from using $GN_2O$ as oxidizer. It is considered that combustion energy is much larger than latent heat energy which was used in the evaporation of liquid oxidizer. However propulsion performance efficiency for $LN_2O$ showed lower value than for $GN_2O$. By increasing the flow rate of liquid oxidizer, heat transfer needed for vaporization of liquid oxidizer was increased, which resulted in the growth of combustion instability.

ANALYSES OF ANNULAR LINEAR INDUCTION PUMP CHARACTERISTICS USING A TIME-HARMONIC FINITE DIFFERENCE ANALYSIS

  • Seong, Seung-Hwan;Kim, Seong-O
    • Nuclear Engineering and Technology
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    • v.40 no.3
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    • pp.213-224
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    • 2008
  • The pumping of coolant in a liquid metal fast reactor may be performed with an annular linear induction electro-magnetic (EM) pump. Linear induction pumps use a traveling magnetic field wave created by poly-phase currents, and the induced currents and their associated magnetic field generate a Lorentz force, whose effect can be the pumping of the liquid metal. The flow behaviors in the pump are very complex, including a time-varying Lorentz force and pressure pulsation, because an induction EM pump has time-varying magnetic fields and the induced convective currents that originate from the flow of the liquid metal. These phenomena lead to an instability problem in the pump arising from the changes of the generated Lorentz forces along the pump's geometry. Therefore, a magneto-hydro-dynamics (MHD) analysis is required for the design and operation of a linear induction EM pump. We have developed a time-harmonic 2-dimensional axisymmetry MHD analysis method based on the Maxwell equations. This paper describes the analysis and numerical method for obtaining solutions for some MHD parameters in an induction EM pump. Experimental test results obtained from an induction EM pump of CLIP-150 at the STC "Sintez," D.V. Efremov Institute of Electro-physical Apparatus in St. Petersburg were used to validate the method. In addition, we investigated some characteristics of a linear induction EM pump, such as the effect of the convective current and the double supply frequency (DSF) pressure pulsation. This simple model overestimated the convective eddy current generated from the sodium flow in the pump channel; however, it had a similar tendency for the measured data of the pump performance through a comparison with the experimental data. Considering its simplicity, it could be a base model for designing an EM pump and for evaluating the MHD flow in an EM pump.