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A Case of Primary Diffuse Nodular Pulmonary Amyloidosis Localized in the Lung (원발성 결절성 폐실질형 유전분증 1예)

  • Jung, Sung-Kwoen;Oh, Joon;Roh, Yang-Won;Kong, Hee-Sang;Park, Kae-Young;Park, Jeong-Woong;Park, Jae-Kyung;Nam, Gui-Hyun;Ha, Seong-Hwen;Lee, Han-Kyung;Jeong, Seong-Hwan
    • Tuberculosis and Respiratory Diseases
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    • v.49 no.3
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    • pp.365-371
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    • 2000
  • Nodular pulmonary amyloidosis is one of the rare manifestation of amyloid disease. It is known to be caused by amyloid L fibrils in the majority of cases. We experienced an unusual case of a forty-one year-old woman who was presented with multiple nodular lesion on the chest X-ray. CT-guided core needle biopsy, performed on the lesion, showed apple green birefringes, when stained Congo red and examined under polarized light, Ultrastructurally, there are randomly oriented, forming densed networks, and consists of fine, 7.5 to 10nm diameter, rigid, non-branching filaments of various lengths in electron-microscopic finding. We report a case of primary diffuse nodular pulmonary amyloidosis only localized in the lung, which was confirmed by CT guided core needle biopsy.

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Study on the Calibration of a Full-Polarimetric Scatterometer System at X-band (X-밴드 완전 편파 Scatterometer 시스템 보정에 관한 연구)

  • Hwang, Ji-Hwan;Park, Seong-Min;Kwon, Soon-Gu;Oh, Yi-Sok
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.4
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    • pp.408-416
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    • 2010
  • A study on the calibration of an X-band HPS(Hongik Polarimetric Scatterometer) system for ground-based operation is presented in this paper. In order to calibrate the scatterometer system, the degree of its distortions are analyzed by comparison between theoretical- and measured-values using the theoretically well-known calibration targets such as a metal sphere, a trihedral corner reflector(CR) and a metal cylinder. The calibration works in the field conditions depend on the precise and stable measurements of those calibration target. we present a measurement technique, so-called, an automatic 2-D target-scanning technique, using the incidence-angle(${\xi}-$ and ${\phi}-$ directions) control of HPS system. Then, we used STCT(Single-Target Calibration Technique) and GCT(General Calibration Technique) to calibrate a distortion of the scatterometer system, and measured the polarimetric RCS(Radar Cross Section) and phase-difference of a trihedral-CR as a test-target to verify the accuracy of the calibration technique. Then, three different types(i.e., 10, 20, 30 cm) of trihedral-CR were used. we obtained the error ranges about ${\pm}1.0$dB, ${\pm}0.5$ dB in a polarimetric RCS and about $-20^{\circ}{\sim}0^{\circ}$ and ${\pm}5^{\circ}$ in the co-polarized phase-difference by using the GCT and STCT, respectively.

Properties analysis of environment friendly calcareous deposit films electrodeposited at various temperature conditions in natural seawater (천연해수 중 온도 변화에 따라 전착한 환경친화적인 석회질 피막의 특성 분석)

  • Lee, Chan-Sik;Kang, Jun;Lee, Myeong-Hoon
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.7
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    • pp.779-785
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    • 2015
  • Cathodic protection is recognized as the most cost-effective and technically appropriate corrosion prevention method for the submerged zone of offshore structures, ships, and deep-sea facilities. When cathodic protection is applied, the cathodic currents cause dissolved oxygen reduction, generating hydroxyl ions near the polarized surface that increase the interfacial pH and result in enhanced carbonate ion concentration and precipitation of an inorganic layer whose principal component is calcium carbonate. Depending on the potential, magnesium hydroxide can also precipitate. This mixed deposit is generally called "calcareous deposit." This layer functions as a barrier against the corrosive environment, leading to a decrease in current demand. Hence, the importance of calcareous deposits for the effective, efficient operation of marine cathodic protection systems is recognized by engineers and scientists concerned with cathodic protection in submerged marine environments. Calcareous deposit formation on a marine structure depends on the potential, current, pH, temperature, pressure, sea-water chemistry, flow, and time; deposit quality is significantly influenced by these factors. This study determines how calcareous deposits form in sea water, and assesses the interrelationship of formation conditions (such as the sea water temperature and surface condition of steel), deposited structure, and properties and the effectiveness of the cathodic protection.

The Mycobacterium avium subsp. Paratuberculosis protein MAP1305 modulates dendritic cell-mediated T cell proliferation through Toll-like receptor-4

  • Lee, Su Jung;Noh, Kyung Tae;Kang, Tae Heung;Han, Hee Dong;Shin, Sung Jae;Soh, Byoung Yul;Park, Jung Hee;Shin, Yong Kyoo;Kim, Han Wool;Yun, Cheol-Heui;Park, Won Sun;Jung, In Duk;Park, Yeong-Min
    • BMB Reports
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    • v.47 no.2
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    • pp.115-120
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    • 2014
  • In this study, we show that Mycobacterium avium subsp. paratuberculosis MAP1305 induces the maturation of bone marrow-derived dendritic cells (BMDCs), a representative antigen presenting cell (APC). MAP1305 protein induces DC maturation and the production of pro-inflammatory cytokines (Interleukin (IL)-6), tumor necrosis factor (TNF)-${\alpha}$, and IL-$1{\beta}$) through Toll like receptor-4 (TLR-4) signaling by directly binding with TLR4. MAP1305 activates the phosphorylation of MAPKs, such as ERK, p38MAPK, and JNK, which is essential for DC maturation. Furthermore, MAP1305-treated DCs transform naive T cells to polarized $CD4^+$ and $CD8^+$ T cells, thus indicating a key role for this protein in the Th1 polarization of the resulting immune response. Taken together, M. avium subsp. paratuberculosis MAP1305 is important for the regulation of innate immune response through DC-mediated proliferation of $CD4^+$ and $CD8^+$ T cells.

Metamorphism of Anorthositic Rocks with Respect to Amphiboles in Hadong Area (각섬석류를 활용한 하동지역 회장암체의 변성작용에 관한 연구)

  • Kwak, Ji Young;Choi, Jin Beom
    • Journal of the Mineralogical Society of Korea
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    • v.28 no.3
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    • pp.221-231
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    • 2015
  • Precambrian Jirisan gneiss complex suffered retrograde metamorphism ranging from granulite facies to the amphibolite facies and/or greenschist facies. Intrusive anorthositic rocks in gneiss complex are influenced by late metamorphism. Mafic mineral in anorthositic rock composed mainly of amphiboles, which can anticipate the information about metamorphic conditions and metamorphic facies. Amphiboles from anorthositic rock show subhedral to anhedral in shape and mostly blueish green and/or green in colour in plane polarized light. Some of brownish amphiboles show zonal texture with brownish to blueish green in color from core to rim. Reaction parts in clinopyroxene which exchange with amphibole. It suggests retrograde metamorphism and/or alteration. Amphiboles composing anorthositic rocks can be classified into two types depending on the size and occurrence of amphibole. The first type is microcrystalline amphibole occurring matrix [Group I: ferrohornblende]. The second type is amphibole with 1 mm or larger in size, which is usually occurred in the boundary between opaque mineral and plagioclase [Group II: ferropargasite]. Electron microscopic analyses base on the $Al^{vi}$ composition in amphiboles suggest that the metamorphic pressure of anorthositic rock was low with 5 kbar or less. Ti compositional range in amphibole and representing hornblende+ plagioclase+garnet+biotite+chlorite mineral assemblage suggest that metamorphic facies of anorthositic rock is in amphibolite facies.

Growth Pattern and Spatial Distribution of One-person Households by Socio-Economic Demographic Characteristicsc (1인 가구의 인구.경제.사회학적 특성에 따른 성장패턴과 공간분포)

  • Lee, Hee-Yeon;Noh, Seung-Chul;Choi, Eun-Young
    • Journal of the Korean Geographical Society
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    • v.46 no.4
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    • pp.480-500
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    • 2011
  • This paper aims to describe the rapid growth of the one-person households in terms of the socio-economic demographic perspectives during the period of 1995-2005 and to analyze the spatial distribution patterns based on different characteristics of one-person households. The increase in the divorce ratio in the middle-aged, the growth of unmarried people the young generation, and the increase of life expectancy in the old generation are explanatory factors for the rise and diversification of one-person households in Korea. The rapid increase of one-person households is accompanied by a diversification in their age, gender, marital status, education level. Uneven distribution of one-person households depends on their age, level of education and dwelling type. Highly educated young adults residing in their own apartment are generally concentrated in major cities, whereas senior citizen with their own single house who lives alone are mostly in rural area. One-person households of the highly educated young adults are significantly polarized in the light of their the living standards. In particular, metropolitan area or big cities are mixed with those who have their own apartment and are financially capacity and with those who rent in a detached single house. As such, one-person households have considerably heterogeneous characteristics. Therefore, each local government will face different economic and social problems based on which group of one-person households are increasing and where they are concentrated in. To this extent, the local government should have differentiated welfare policy according to its own respect.

A Study on Precarious Labor of Korean Game Workers : Focusing on reward and career prospect (게임 생산자의 노동 불안정성 연구: 보상 및 경력전망을 중심으로)

  • Lee, Sangkyu;Lee, Yong-Kwan
    • The Journal of the Korea Contents Association
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    • v.19 no.11
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    • pp.337-352
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    • 2019
  • This study aims to explore the characteristics of the working conditions in Korean game industry, focusing on the precarity of game workers. As a research methodology, qualitative and quantitative methods were combined. Specifically, in addition to in-depth interviews with game workers, we conducted a quantitative analysis on adequacy of reward and career prospects recognized by game workers through the Korean Working Conditions Survey(2014/2017). The major findings are as follows. First, game workers were experiencing labor precarity in a way of job insecurity, economic instability and excessive exploitation, as well as loss of autonomy and labor alienation. Second, between 2014 and 2017, the adequacy of reward recognized by game workers was positively improved for companies with 30 or more employees, but was worsen for those with less than 30 employees. In addition, in terms of career prospects, there were no significant changes in the workers of companies with 30 or more employees, but the were worsened for companies with less than 30 employees. These results show that labor precarity in the game industry appears to be different depending on various factors, such as business size, occupation, and career. It also implies that the polarized and inequal structure of the Korean game industry is gradually deepening.

Clarification of Apple Vinegar by Ultrafiltration and Flux Charcateristics (한외여과를 이용한 사과식초의 청징화와 투과특성)

  • Kim, Soon-Dong;Chung, Ho-Duck;Choi, Yong-Hee;Youn, Kwang-Sup
    • Applied Biological Chemistry
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    • v.43 no.1
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    • pp.24-28
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    • 2000
  • This study was conducted to evaluate the effect of ultrafiltration (UF) process variables on permeate flux and membrane resistance and to clarify apple vinegar for quality improvement. Apple vinegar was clarified in a laboratory ultrafiltration system with hollow fiber membrane made of polysulfone and MWCO 30,000 and 10,000. The permeate flux increased with the increase of flow rate and the optimum pressure was $1.5\;kgf/cm^2$ in this system. The turbidity of clarified apple vinegar treated UF largely decreased. pH and acidity of treated samples showed the same level as those of untreated apple vinegar. The permeate flux continuously declined while the fouling material accumulated on the membrane as the operation time increased. Resistance decreased with lower pressure, which could be explained by expansion of pore size at lower pressure and minor compaction of the polarized layer at lower pressure.

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Magnetic Properties of Mn-substituted Magnetite Thin Films (망간 치환된 마그네타이트 박막의 자기적 특성 연구)

  • Lee, Hee-Jung;Kim, Kwang-Joo
    • Journal of the Korean Vacuum Society
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    • v.16 no.4
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    • pp.262-266
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    • 2007
  • Polycrystalline $Mn_xFe_{3-x}O_4$ thin films were synthesized on Si(100) substrates using sol-gel method and the effects of Mn substitution on the structural, magnetic, and magnetotransport properties were analyzed. X-ray diffraction revealed that cubic structure is maintained up to x = 1.78 with increasing lattice constant for increasing x. Such increase of the lattice constant is attributable to the substitution of $Mn^{2+}$ (with larger ionic radius) ions into tetrahedral $Fe^{3+}$(with smaller ionic radius) sites. VSM measurements revealed that $M_s$ does not vary significantly with x, qualitatively explainable by comparing spin magnetic moments of Mn and Fe ions. On the other hand, $H_c$ was found to decrease with increasing x, attributable to the decrease of magnetic anisotropy due to the decrease of $Fe^{2+}$ density through $Mn^{2+}$ substitution. Magnetoresistance (MR) of the $Mn_xFe_{3-x}O_4$ films was found to decrease with increasing x. Analysis of the MR data in comparison with the VSM results gives an indication of the tunneling of spin-polarized carriers through the grain boundaries of the polycrystalline samples at low external field and spin-flip of the carriers at high external field.

XAS Studies of Ion Irradaited MgO Thin Films

  • Suk, Jae-Kwon;Gautam, Sanjeev;Song, Jin-Ho;Lee, Jae-Yong;Kim, Jae-Yeoul;Kim, Joon-Kon;Song, Jong-Han;Chae, Keun-Hwa
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.312-312
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    • 2012
  • Magnesium oxide has become focus for research activities due to its use in magnetic tunnel junctions and for understanding of do ferromagnetism. Theoretical investigations on such type of system indicate that the presence of defects greater than a threshold value is responsible for the magnetic behaviour. It has also been shown experimentally that by decreasing the film thickness and size of nanoparticles, enhancement/increase in magnetization can be achieved. Apart from the change in dimension, swift heavy ions (SHI) are well known for creating defects and modifying the properties of the materials. In the present work, we have studied the irradiation induced effects in magnesium oxide thin film deposited on quartz substrate via X-ray absorption spectroscopy (XAS). Magnesium oxide thin films of thickness 50nm were deposited on quartz substrate by using e-beam evaporation method. These films were irradiated by 200 MeV Ag15+ ion beam at fluence of $1{\times}10^{11}$, $5{\times}10^{11}$, $1{\times}10^{12}$, $3{\times}10^{12}$ and $5{\times}10^{12}ions/cm^2$ at Nuclear Science Centre, IUAC, New Delhi (India). The grain size was observed (as studied by AFM) to be decreased from 37 nm (pristine film) to 23 nm ($1{\times}10^{12}ions/cm^2$) and thereafter it increases upto a fluence of $5{\times}10^{12}ions/cm^2$. The electronic structure of the system has been investigated by X-ray absorption spectroscopy (XAS) measurements performed at the high energy spherical grating monochromator 20A1 XAS (HSGM) beamline in the National Synchrotron Radiation Research Center (NSRRC), Taiwan. Oxides of light elements like MgO/ZnO possess many unique physical properties with potentials for novel application in various fields. These irradiated thin films are also studied with different polarization (left and right circularly polarized) of incident x-ray beam at 05B3 EPU- Soft x-ray scattering beamline of NSRRC. The detailed analysis of observed results in the wake of existing theories is discussed.

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