• The Korean Journal of Pesticide Science
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• v.3 no.1
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• pp.13-19
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• 1999

Insecticidal potentials of polar and non-polar tractions obtained from 84 medicinal plants were screened against five major agricultural insects. Based on the primary and secondary screening results, non-polar fraction of Atractylodes koreana Kitam. rhizomes was selected to isolate and identify an active compound effective to diamondback moth (Plutella xylostella L.) larvae. Counter-current distribution separation on the non-polar fraction and TLC and spectroscopic analyses (GC-MS and $^{1}H$- and $^{13}C$-NMR) revealed that molecular formula of the active compound was $C_{15}H_{22}O$ known as a sesquiterpenoid 4,11-selinadien-3-one (${\alpha}$-cyperone). However, ${\alpha}$-cyperone was not detected in the non-polar fractions that showed high insecticidal potential against the diamondback moth. Although ${\alpha}$-cyperone has been first identified from Cyperus rotundus, the compound did not occur in C. rotundus cultivated in Korea.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.351.1-351.1
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• 2002

Heterocyclic compounds with oxygen atoms are known to have potent biological effect. The flavonoids. isoflavonoids. and coumarins which form the bulk of these compounds are very polar and have limited use as drugs which have to pass through membranes. The non-polar property is increased by exchange oxygen to selenium as a part of heterocyclic compound. Our group is focused on synthesizing selenoheterocyclic compound with the above property. (omitted)

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.7 no.1
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• pp.3-18
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• 1997

This study was conducted to evaluate desorption efficiencies by types of desorption solvent for polar and non-polar organic compounds collected on activated charcoal tubes. Analytes tested were toluene, m-xylene, isobutyl alcohol, n-butyl alcohol, cellosolve acetate, and butyl cellosolve. Three different concentration levels of spiked sample were made. Types of cosolvent mixed with the main solvent, $CS_2$, were methanol, pentanol, and dimethylformamide (DMF) and the cosolvent for methylenechloride was methanol. The amounts of cosolvent added to the main solvent were 1, 5, and 10% by volume (v/v%), respectively. The results were as follows: 1. For all mixed solvents except 1% methanol and 1% pentanol with $CS_2$, desorption efficiency significantly increased, compared with that of $CS_2$ alone. 2. Desorption efficiency increased by increasing analyte loading on charcoal tube regardless of mixed solvents used and the material polarity. 3. For all cosolvents mixed with $CS_2$ by 1% and 5% volume, desorption efficiency for non-polar compound was significantly higher than that of polar compound. For the 10% mixed solvents and the methylenechloride mixed with methanol, the results were opposite. 4. The lowest mean percent bias of 4.79% was obtained from the 5% DMF-$CS_2$ mixed solvent, followed by 4.82% from the 10% DMF-$CS_2$ solvent while the highest bias of 23.26% was from the solvent of $CS_2$ alone. Based on the results of this study, in order to increase desorption efficiency, it is recommended to add such cosolvents as methanol, pentanol, and DMF to $CS_2$, preferably 5% by volume for analyzing polar compounds collected in charcoal tubes.

• YAKHAK HOEJI
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• v.54 no.4
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• pp.300-308
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• 2010

Adrenoceptor has been considered to be an important target in psychiatric disorders. Based on x-ray structures of bovine rhodopsin, we established homology model of ${\alpha}_{2c}$-adrenoceptor (ADA2C_rat) and then analyzed docking from binding model of receptor-ligand complex with high-active compound No.29 in tricyclic isoxazole analogues (1-30). We observed that the N (1.907 $\AA$) and O (1.712 $\AA$) atoms of isoxazole ring on the docked ligand (No.29) formed H-bonding interaction with O-H of Ser5.32 and carmeron phenyl ring centroid of tricyclic isoxazole formed $\pi-\pi$ interaction at 3.342 $\AA$ distance with phenyl ring centroid of Phe6.52. According to predictions of blood-brain distribution (logBB) through penetration of blood-brain barrie (BBB) and polar surface area (PSA) of the ligands, the high-active compound No.29 has values of logBB=-0.203, PSA=67.50, respectively. These results suggest that the high-active compound No.29 is a novel anti-depressant with the characteristics such as dopamine and serotonin.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.182.1-182.1
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• 2003

Flavonoids with oxygen atoms are known to have potent biological effect.They have been studied long as major antioxidants which protect cell membranes. Recent medical surveys show that increased intake of selenium decreases the risk of breast, colon, lung and prostrate cancer by preventing free radical generation. The flavonoids, isoflavonoids, and coumarins which form the bulk of these compounds are very polar and have limited use as drugs which have to pass through BBB(Brain Blood Barrier)The non-polar property is increased by exchange oxygen to selenium as a part of heterocyclic compound. (omitted)

• Polymer(Korea)
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• v.35 no.3
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• pp.228-231
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• 2011

The rate of vulcanization of nonpolar ethylene-propylene-diene terpolymer(EPDM)/carbon black compounds was investigated by using hot air and microwave as a heating source. The present study parameters such as heating source, sample thickness, and loading of an additive. The compound thickness was the main factor in the hot air vulcanization. It was due to the poor thermal conductivity of EPDM; that is, the thicker thickness, the lower vulcanization rate. For 100% vulcanization, the compound with 3 mm thickness required 7 min at $250^{\circ}C$ in the hot air system. However, the vulcanization of EPDM compounds by microwave system was not affected by the thickness while strongly dependent on the amount of a polar additive, carbon black. A compound with 80 phr of carbon black was perfectly vulcanized within 30 sec. These results suggest that the use of microwave as a heating source is an effective method for the vulcanization of compounds including a polar component.

• Applied Chemistry for Engineering
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• v.8 no.3
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• pp.510-516
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• 1997

O/W emulsions were prepared by adding water to the solution containing amphiphilic resin and the mixed emulsifier of cetyl alcohol polyoxyethylene(20) sorbitan monooleate. Phase behavoir of these emulsions was studied at various HLB(Hydrophilic Lipophilic Balance) values and temperatures. The polar oil emulsion containing the amphiphilic resin showed improved phase stability at various temperatures. Model compounds which contain one of the functional groups in the amphiphilic resin were used in the polar oil phase in order to study the effect of interaction between the functional group and the emulsifier on the phase stability of emulsion. These model compound emulsions showed the phase stability order of poly(acrylic acid)

• Proceedings of the Korean Vacuum Society Conference
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• 2010.08a
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• pp.259-259
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• 2010

Periodically polarity inverted (PPI) ZnO structures on (0001) Al2O3 substrates are demonstrated by plasmas assisted molecular beam epitaxy. The patterning and re-growth methods are used to realize the PPI ZnO by employing the polarity controlling method. For the in-situ polarity controlling of ZnO films, Cr-compound buffer layers are used.[1, 2] The region with the CrN intermediate layer and the region with the Cr2O3 and Al2O3 substrate were used to grow the Zn- and O-polar ZnO films, respectively. The growth behaviors with anisotropic properties of PPI ZnO heterostructures are investigated. The periodical polarity inversion is evaluated by contrast images of piezo-response microscopy. Structural and optical interface properties of PPI ZnO are investigated by the transmission electron microcopy (TEM) and micro photoluminescence ($\mu$-PL). The inversion domain boundaries (IDBs) between the Zn and the O-polar ZnO regions were clearly observed by TEM. Moreover, the investigation of spatially resolved local photoluminescence characteristics of PPI ZnO revealed stronger excitonic emission at the interfacial region with the IDBs compared to the Zn-polar or the O-polar ZnO region. The possible mechanisms will be discussed with the consideration of the atomic configuration, carrier life time, and geometrical effects. The successful realization of PPI structures with nanometer scale period indicates the possibility for the application to the photonic band-gap structures or waveguide fabrication. The details of application and results will be discussed.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.62-62
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• 2019

Natural substances have various physiological activities. Substances isolated from natural substances are known to be safer and more potent than pharmaceuticals. Potatoes not only act as energy sources but also contain active ingredients such as vitamins and minerals. In particular, the potato contains a large amount of polar compounds, including the saponin in the polar compounds, and the physiological activity of the saponins, such as immunity enhancement, antioxidant and anti-inflammatory is known. In this study, the antioxidative activity of polar compounds from five potatoes was examined by chemical base anti-oxidation assay and cell based anti-oxidation assay. In the chemical base anti-oxidation assay, DPPH experiment showed activity in the order of Hongyoung, Haryung, Seohong, Sumi, and Jayoung. In the LPA experiment, IC50 was lower in the order of Jayoung, Seohong, Sumi, Hongyoung, and Haryung. In the cell based anti-oxidation assay, the smallest amount of ROS was generated when the compound was derived from Haryung and hongyoung, and strong SOD activity was observed in Sumi and Jayoung. The results of this study reveal the antioxidative effect of polar compounds extracted from various kind of potatoes, which will enable the acquisition of new bioactive candidates and the establishment of new profit generation models for farmers.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.6
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• pp.1033-1037
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• 2001

Garlic oleoresins were made by extracting with four solvents of methanol, methyl acetate hexane and acetone from chopped garlic, respectively, and the volatile compounds of each extract were separated by gas chromatography installed with polar (supelcowax-10$^{TM}$) and nonpolar (HP-5) capillary columns, respectively, and identified by matching mass data of mass selective detector and Kovat\`s retention index with references. The numbers of the volatile compounds identified the garlic oleoresin by polar and nonpolar columns from in garlic oleoresins were 41 and 32, respectively. In polar column, 13 pyrans, 11 sulfur-containing compounds 6 furans 2 alcohols and 2 heterocyclic compounds were identified. In nonpolar column, 11 sulfur-containing compounds 5 acids 3 furans and eugenol were identified. The major sulfur-containing compounds identified from the oleoresins were 3, 3'-thiobis-1-propene, methyl 2-propenyl disulfide, dimethyl trisulfide, di-2-prnpenyl-trisulfide, 2-thiophenecarboxylic acid. The amount of these sulfur-containing compounds isolated from the oleresins were more abundant in polar column than in nonpolar column. The most efficient solvent for extracting volatile compounds of garlic was methanol but the most useful solvent for extracting sulfur-containing compounds was methyl acetate of less polarity.y.