• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3307-3312
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• 2015

The papillary patterned lesion of thyroid may be challenging with many diagnostic pitfalls. Tumor stroma plays an important part in the determination of the tumor phenotype. CD34 is thought to be involved in the modulation of cell adhesion and signal transduction as CD34(+) fibrocytes are potent antigen-presenting cells. Smooth muscle actin (SMA) positivity could be diagnostic for fibroblast activation during tumorigenesis. We aimed to examine the expression of CD34 and alphaSMA in the stroma of papillary thyroid hyperplasia, papillary thyroid carcinoma and papillary tumors of uncertain malignant potential in order to elucidate their possible differential distribution and roles. A total number of 54 cases with papillary thyroid lesions were studied by routine H&E staining, CD34 and ASMA immunostaining. ASMA was not expressed in benign papillary hyperplastic lesions while it was expressed in papillary carcinoma, indicating that tumors have modulated stroma. Although the stroma was not well developed in papillary lesions with equivocal features of uncertain potentiality, CD34 was notable in such cases with higher incidence in malignant cases. So ASMA as well as CD34 could predict neoplastic behavior, pointing to the importance of the stromal role. Differences between groups suggest that the presence of CD34 + stromal cells is an early event in carcinogensis and is associated with neoplasia, however ASMA+ cells are more likely to be associated with malignant behavior and metastatic potential adding additional tools to the light microscopic picture helping in diagnosis of problematic cases with H&E.

• Asian Pacific Journal of Cancer Prevention
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• 제13권10호
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• pp.5195-5199
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• 2012

Objectives: Global cancer statistical data show that India has one of the highest incidence rates of oral cancer worldwide. Early detection is extremely important as it results in lower morbidity and death rates. The present study was undertaken to assess awareness of oral cancer and knowledge of its early signs and risk factors in the general public of the semi-urban Gorakhpur area of Uttar Pradesh (India). It was also intended to educate the same population for early detection by increasing their ability to recognize signs and risk factors. Method: A questionnaire-based household survey was conducted over a period of one month in different parts of Gorakhpur district, a region where tobacco use is apparently very high. A total of 2,093 persons participated in the survey. The collected data were analyzed using SPSS software to assess and associate oral cancer awareness with the prevalence, and abstract risk factors, as well as other confounding variables. Results: The general awareness, knowledge of signs and risk factors of oral cancer were found to be proportionate to the literacy level with the highest rate of awareness being among high school and graduates and lowest among illiterates. It was also observed that on most of these dimensions the younger age groups (<30 years) were significantly more knowledgeable. Conclusion: Overall, the awareness of oral cancer in the high-risk population of Gorakhpur was not satisfactory, pointing to a need for further dissemination of information on this issue and its associated risks. This is especially important for the youngsters, as this may possibly help them keep away from the deleterious habit of tobacco indulgence in any form. If necessary risk factor cessation counselling should be provided.

• 한국콘텐츠학회논문지
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• 제16권4호
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• pp.624-633
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• 2016

빅 데이터의 시대 수많은 정보들이 출몰하고 있고 이를 효과적으로 전달하기 위한 인포그래픽 연구들이 이슈화되고 있지만 신용카드명세서를 통해 전달되는 수치정보에 대한 시각화연구는 그 중요성에 비해 매우 미흡하다. 신용카드이용명세서를 중심으로 수치정보 유형을 분석하여 각 정보특성에 따른 효과적인 시각화방법이 무엇인지 연구하였다. 수치정보의 유형은 비교분석, 시간변화의 추이, 비율, 관계, 범위와 분포 등으로 모색되었고 각 정보의 특성에 적합한 그래프형태로 제작하여 가장 효과적이고 이상적인 시각적 형태를 연구하였다. 따라 본 연구는 수치특성을 갖고 있는 신용카드이용명세서에 나타난 수치정보를 전달하기 위한 효과적인 시각적 형태를 짚어줌으로서 시각화의 기준점을 제시하는 의미가 있다.

• 한국콘텐츠학회논문지
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• 제5권2호
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• pp.187-197
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• 2005

본 논문에서는 위치 기반 서비스에서 이동 객체의 궤적을 색인하기 위해 기존에 제안되었던 TB-트리의 성능을 개선시킬 수 있는 확장된 TB-트리(Extented TB-Tree:ETB-Tree)를 제안한다. ETB-트리는 선행 노드를 직접적으로 접근하기 위해 이동 객체의 처음 세그먼트와 마지막 세그먼트가 저장된 단말 노드를 가리키는 포인터 정보와 더불어 디스크에서의 페이지를 가리키는 페이지 번호를 별도의 테이블에 같이 유지함으로써 저장시 동일한 이동 객체의 선행노드를 빨리 검색할 수 있고, 궤적 질의시에도 바로 디스크에 접근해 해당 객체의 제적들을 검색함으로써 검색 성능을 향상시킬 수 있다. 아울러 ETB-트리는 새로운 이동 객체의 제적 정보가 삽입될 때마다 메모리 상의 트리 구조 뿐만 아니라 디스크에 반영함으로써 트리의 일관성을 유지한다. 마지막으로, 성능 평가를 분석한 결과, 제안하는 색인 기법이 기존의 색인 기법들에 비해 삽입과 제적 질의의 검색 측면에서 더 우수함을 보임을 알 수 있다.

• Journal of Astronomy and Space Sciences
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• 제13권2호
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• pp.105-116
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• 1996

이 연구는 1992년 8월 11일과 1993년 9월 26일 발사된 우리별 1호 및 우리별 2호의 열제어 모델 및 그 동안의 운용 결과에 대한 해석을 바탕으로 한 것이다. 우리별 1, 2호는 아리안 발사체의 초소형 위성 탑재를 위한 특수 구조물에 장착되어 발사되었기 때문에 크기, 전력, 무게 등의 제한으로 인해 외부로부터의 열 흡수와 방출의 제어 및 내부의 연결 모듈간의 열 흐름을 제어하여 위성체 전반의 열적 환경을 조절하는 수동적인 방식의 열제어를 채택하게 되었다. 우리별 위성의 주 임무는 위성 기술의 개발과 더불어 위성체 바닥면에 탑재된 CCD 카메라를 이용하여 지구 표면을 촬영하는 것이었기 때문에 위성의 바닥면은 항상 지구의 중심을 향하고 있게 된다. 이 연구는 위성의 임무 궤도에 대한 분석으로부터 열 모델링, 시뮬레이션 결과 및 우리별 2호의 실제 운용헤서 얻어진 원격검침 정보를 바탕으로 한 열 모델의 평가를 포함한다. 이 분석 결과를 바탕으로 수동 제어에 의한 우리별 위성의 열 모델 및 해석이 실제 측정된 온도 데이터와 평균 오차 $$10^{\circ}C$ 이내에서 일치되었음을 보여 준다.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2013년도 춘계학술대회 논문집
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• pp.390-394
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• 2013

고정밀 광학계를 탑재한 관측 위성은 매우 높은 지향 안정성을 요구하지만 인공위성의 자세 제어를 위해 사용하는 반작용 휠, 극저온 냉각을 위한 cooler 등 다양한 진동원에 의해 미소 진동이 발생할 수 있다. 고정밀 탑재체를 외부 진동으로부터 보호하기 위한 가장 일반적인 방법은 진동이 전달되는 경로에 진동 절연장치를 도입하는 것이다. 본 논문에서는 미소진동 절연을 위한 1 축 능동 진동 절연장치의 개발 및 진동 절연 성능 시험을 기술하였다. 개발한 절연장치의 고유진동수를 조절하기 위해 원하는 강성을 갖는 membrane 구조를 설계하였으며 능동 제어를 위해 전자석을 사용하였다. 절연장치의 성능 시험 결과를 통해 능동 제어 시 고주파수 대역에서 절연성능의 저하 없이 공진의 크기를 줄일 수 있는 것과 개발된 진동 절연 장치가 미소 진동을 효과적으로 절연할 수 있는 것을 확인하였다.

• 대한유전성대사질환학회지
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• 제11권1호
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• pp.88-98
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• 2011

Lesch-Nyhan syndrome is a X-linked recessive disorder caused by a deficiency of the enzyme hypoxanthine-guanidine phosphoribosyltransferase (HPRT), enzyme to recycle purines. Case history: born induced vaginal delivery at 40 weeks complicated by premature membrane ruputure, body weight 2.820 gm. He showed failure to thrive showing severe protein aversion like milk products and pink daper. Developmental delay revealing rolling over at 10.5 month, followed by regression. Seizure at 2 months, His poor oral feeding was lifelong problem. Weak crying, spastic, choreoathetoid movement. Self mutilating behavior noted and diagnosed at age 3 years. No family history of consanguinity and neurological disorders. Method: Laboratory test, physical exam, imaging study and molecular. Clinical follow up Treat ment with allopurinol. Result: uric acid 10.5 mg/dL (N 3.5-7.9), APRT 151.1uM/ min/ml pro(25.7-101), HPRT 7.6 (N 233.5-701) and c.151C>T hemizygote (p,Arg51X). Abdominal sonogram showed staghorn calculi in both kidneys, brain MRI brain atrophy. Clinical follow up showed, seizure at 2 mo, developmental delay (head control and, rolling over at at 11mo, pointing body part at 2 yr 7 mo, eye hand coordination at 2 y 11mo,creeping at 3 y 7 mo, speaking words at 6 y 6 mo ),and developmental regression at 3 yr of age. Sleeping problem including insomnia and severe constipation. Self mutilating behavior (lip bite) started at 2.5 yr, neurologic sx including intermittent upward gaze accompanied by swallowing difficulty at 3 y 7 mo grand mal seizure at 4.5 yr and spastic extremity and trunchal hypotonia and choleoathetoid movement and ataxia at 6.5 yr. Scoliosis with severe spasticity at 9 yr 9 mo. Acute life threatening episode with irregular breathing at 9 yr and 9 mo, Emaciation and nephrolithiasis and recurrent pneumonia. Died suddenly at 10 yr 3 mo. Conclusion: life long feeding problem, chronic gut motility dysfunction, sleeping difficulty and progressing neurologic deterioration and nephrolithiasis despite normal serum uric acid maintence by allopurinol treatment.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 1998년도 Proceedings of International Symposium on Remote Sensing
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• pp.301-306
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• 1998

Korea Aerospace Research Institute (KARI) is developing a Korea Multi-Purpose Satellite I (KOMPSAT-I) which accommodates Electro-Optical Camera (EOC), Ocean Scanning Multi-spectral Imager (OSMI), and Space Physics Sensor (SPS). The satellite has the weight of about 500kg and will be operated on the 10:50 AM sun-synchronized orbit with the altitude of 685 km. The satellite will be launched in 1999 and its lifetime is expected to be over 3 years. The main mission of EOC is the cartography to provide the images from a remote earth view for the production of 1/25000-scale maps of KOREA. EOC collects 510 ~ 730 nm panchromatic imagery with the ground sample distance(GSD) of 6.6 m and the swath width of 17 km by push broom scanning. EOC also can scan $\pm$45 degree across the ground track using body pointing method. The primary mission of OSMI is worldwide ocean color monitoring for the study of biological oceanography. It will generate 6 band ocean color images with 800 km swath width and 1km GSD by whiskbroom scanning. OSMI is designed to provide on-orbit spectral band selectability in the spectral range from 400 nm to 900 nm through ground command. This flexibility in band selection can be used for various applications and will provide research opportunities to support the next generation sensor design. SPS consists of High Energy Particle Detector (HEPD) and ionosphere Measurement Sensor (IMS). HEPD has missions to characterize the low altitude high-energy Particle environment and to study the effects of radiation environment on microelectronics. IMS measures densities and temperature of electrons in the ionosphere and monitors the ionospheric irregularities at the KOMPSAT orbit.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 1998년도 Proceedings of International Symposium on Remote Sensing
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• pp.313-318
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• 1998

Electro-Optical Camera(EOC) is the main payload of Korea Multi-Purpose SATellite(KOMPSAT) with the mission of cartography to build up a digital map of Korean territory including Digital Terrain Elevation Map(DTEM). This instrument which comprises EOC Sensor Assembly and EOC Electronics Assembly produces the panchromatic images of 6.6 m GSD with a swath wider than 17 km by push-broom scanning and spacecraft body pointing in a visible range of wavelength, 510 ~ 730 nm. The high resolution panchromatic image is to be collected for 2 minutes during 98 minutes of orbit cycle covering about 800 km along ground track, over the mission lifetime of 3 years with the functions of programmable rain/offset and on-board image data storage. The image of 8 bit digitization, which is collected by a full reflective type F8.3 triplet without obscuration, is to be transmitted to Ground Station at a rate less than 25 Mbps. EOC was elaborated to have the performance which meets or surpasses its requirements of design phase. The spectral response the modulation transfer function, and the uniformity of all the 2592 pixel of CCD of EOC are illustrated as they were measured for the convenience of end-user. The spectral response was measured with respect to each gain setup of EOC and this is expected to give the capability of generating more accurate panchromatic image to the EOC data users. The modulation transfer function of EOC was measured as greater than 16% at Nyquist frequency over the entire field of view which exceeds its requirement of larger than 10%, The uniformity that shows the relative response of each pixel of CCD was measured at every pixel of the Focal Plane Array of EOC and is illustrated for the data processing.

• 한국소음진동공학회논문집
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• 제22권11호
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• pp.1042-1048
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• 2012

A 2-axis gimbal system is one of main disturbance sources affecting image jitter response of a satellite. The gimbal system comprises azimuth stage and elevation stage, and these pointing mechanism can be rotated by stepping motors about its azimuth and elevation axes simultaneously. Because of the complex and coupled dynamic motion of the gimbal system, its moment of inertia and structural modes can be changed according to the system configuration, and thus the gimbal system generates complicated and non-linear disturbance characteristics. In order to improve the jitter response of a spacecraft, it is an indispensable process to reduce the micro-vibration disturbance level of the antenna system. In the present research, a 2-axis gimbal system was manufactured and then its micro-vibration test was performed in terms of two types of stepping motors(2-phase and 5-phase). The test results show that the disturbance level of the gimbal system can be reduced by replacing the 2-phase stepping motor with the 5-phase one, and the average disturbance attenuation ratio is 56 % in peak level and 48 % in standard deviation level. The experimental results confirm that it is an efficient jitter reduction method to adopt a high-phase stepping motor.