• 제목/요약/키워드: point to point (P2P)

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만성 비염 환자의 한방코분무제에 대한 효과 및 만족도 조사 (Survey on Effect and Satisfaction of Korean Medicine Distillate Nasal Spray of Patient with Chronic Rhinitis)

  • 김지은;홍철희
    • 한방안이비인후피부과학회지
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    • 제25권3호
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    • pp.56-64
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    • 2012
  • Objectives : This study was performed in order to investigate an immediate improvement effect of nasal obstruction after having patient with chronic rhinitis use nasal spray in nasal cavity after distilling Korean medicine, satisfaction for its fragrance and irritation and its effect continuance time. Methods : A questionnaire was performed for an immediate therapeutic effect of nasal spray 1, 2 and 3 weeks later after using spray by targeting 13 patients who used Korean medicine distillate spray for over 3 weeks among the patients who visited Sangji University Korean Medicine Hospital and whose symptoms were determined as chronic rhinitis and for whom Korean medicine distillate spray was prescribed. 3 weeks later after using spray, a questionnaire was performed for fragrance, irritation and continuance effect of Korean medicine. Immediate therapeutic effect being felt right after spraying was also surveyed and symptom scores was expressed from 10 to 0 and on the assumption that nasal obstruction symptom just before spraying was 10 points, symptom score after spraying was surveyed. In case of evaluation of satisfaction, satisfaction for fragrance and irritation of nasal spray was evaluated by scale based on full score of 5 point from 'very satisfied=5', 'satisfied=4', 'average=3', 'unsatisfactory=2' and 'very unsatisfactory=1', respectively. Effect continuance time after spraying was surveyed by dividing it into within 5 minutes, within 5-10 minutes, within 10-30 minutes and over 30 minutes. All the data was statistically analyzed by Friedman Test that is non-parametric test of Paired t-test and descriptive statistics. Results : Total surveyed patients were 13 persons including 6 males and 7 females and total average age was represented to be $27.1{\pm}17.7$ years old. Score of immediate nasal obstruction improvement effect at 1st week was $6.3{\pm}2.4$ points, at 2nd week $5.7{\pm}2.5$ points and at 3rd week $5.5{\pm}2.5$ points and when comparing 1st week, 2nd week and 3rd week statistically, p value was 0.047<0.05 and from this, it could be seen that the longer spray was used, the more was improvement effect represented with slight significance. In case of fragrance and irritation, both of its score was represented to be high as average $4.0{\pm}1.08 $points and average $4.4{\pm}0.8$ points, respectively. Effect continuance time below 10 minutes was represented in 8 persons who accounted for 61.5%. Conclusions: Immediate improvement effect of nasal obstruction being felt by the patients by using Korean medicine nasal spray could be confirmed and by having the patients use such spray for 3 weeks continuously, it could be realized that such effect was sustained and satisfaction for fragrance or irritation of Korean medicine nasal spray was significant. However, rather short sustained time was considered to be unsatisfactory and this shortcomings is required to be improved in the future.

크론병에서 자기공명영상 장운동기록의 단일호흡 단발 고속 스핀 에코기법: 딥러닝 기반 재구성의 영향 (Impact of Deep-Learning Based Reconstruction on Single-Breath-Hold, Single-Shot Fast Spin-Echo in MR Enterography for Crohn's Disease)

  • 박언주;이예다운;이준성
    • 대한영상의학회지
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    • 제84권6호
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    • pp.1309-1323
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    • 2023
  • 목적 크론병 환자의 자기공명영상 장운동기록(MR enterography; 이하 MRE)에서 단발 고속 스핀 에코기법(single-shot fast spin-echo; 이하 SSFSE)을 이용한 단일호흡영상(singlebreath-hold; 이하 SBH)과 다호흡영상(multiple-breath-hold; 이하 MBH)을 딥러닝 기반 재구성(deep-learning based reconstruction; 이하 DLR)의 유무에 따라 네 개의 영상에서 품질을 비교했다. 대상과 방법 이 연구는 후향적 연구로서, 크론병으로 MRE를 시행한 61명의 환자가 포함되었다. SBH와 MBH SSFSE 영상에서 각각 DLR과 고식적 재구성(conventional reconstruction; 이하 CR)을 시행한 영상을 획득했다. 두 명의 영상의학과 전문의가 네 가지 영상을 분석하여 전반적인 영상의 품질, 인공물, 선명도와 움직임 관련 신호 손실에 대하여 각각 5점 척도를 이용해 점수를 부여했다. 회장과 말단 회장, 결장에서 염증을 시사하는 세 가지 소견을 평가했다. 각 영상에 대해서 공간적 불일치 여부를 확인했고, 네 가지 영상에서 각각 다른 두 위치에서 신호 대 잡음비(signal-to-noise ratio; 이하 SNR)를 계산했다. 결과 SBH SSFSE 영상에서 DLR을 적용한 경우 CR보다 영상의 품질, 인공물, 선명도가 통계학적으로 유의하게 개선되었다. 네 가지 영상 중 SBH-DLR 영상에서 SNR이 가장 높게 나타났다(p < 0.001). 염증 소견에 대한 판독자 간 일치율은 좋음에서 매우 좋음으로 나타났고(κ = 0.76-0.95) 시퀀스 간 일치율은 매우 좋음으로 측정되었다(κ = 0.92-0.94). 공간적 불일치는 SBH 영상보다 MBH 영상에서 통계학적으로 유의하게 빈도가 높았다(p < 0.001). 결론 SBH-DLR 영상은 MBH-CR 영상과 비교했을 때 동등한 영상 품질과 성능을 보여주었다. 또한, MBH 영상에 비해 절반 이하의 시간과 단일 호흡만으로 영상을 획득할 수 있으며 공간 불일치를 줄일 수 있는 대체제로 사용할 수 있다.

Selection signature reveals genes associated with susceptibility loci affecting respiratory disease due to pleiotropic and hitchhiking effect in Chinese indigenous pigs

  • Xu, Zhong;Sun, Hao;Zhang, Zhe;Zhang, Cheng-Yue;Zhao, Qing-bo;Xiao, Qian;Olasege, Babatunde Shittu;Ma, Pei-Pei;Zhang, Xiang-Zhe;Wang, Qi-Shan;Pan, Yu-Chun
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권2호
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    • pp.187-196
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    • 2020
  • Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (FST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r2 = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r2 = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

Arthroscopic Rotator Cuff Repair: Serial comparison of outcomes between full-thickness rotator cuff tear and partial-thickness rotator cuff tear

  • Park, Jin-Young;Chung, Kyung-Tae;Yoo, Moon-Jib
    • Clinics in Shoulder and Elbow
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    • 제6권1호
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    • pp.72-79
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    • 2003
  • Purpose: To compare the results of arthroscopic rotator cuff repair and subacromial decompression in partial thickness rotator cuff tear (PTRCT) with those in full thickness rotator cuff tear (FTRCT). Subjects and method: Of the 46 patients who were rested of the rotator cuff tear based on the operational findings, 42 patients who were able to receive a serial follow-up for 2 years were selected as the study subjects. The average age of the patients at the time of the operation was 55 years, and the mean duration of the follow-up was 34 months. The subjects included 22 cases of PTRCT and 20 cases of FTRCT. In terms of rotator cuff repair, the average number of tendon to tendon repair (TTR) was 1 in both PTRCT and FTRCT, and that of tendon to bone repair (TBR) was 1 and 3 in PTRCT and FTRCT, respectively. The average number of use of suture anchor was 1 and 2 in PTRCT and FTRCT, respectively. The level of shoulder pain and function of the subjects were measured using shoulder functional evaluation score of American shoulder and elbow society (ASES score) at before and 2 years following the operation. Results: At the final follow-up following the operation, PTRCT group showed changes in scores from 7.2 to 0.9 on average pain score and 34 to 91 on ASES score, whereas FTRCT group showed changes in scores from 7.6 to 1.2 on pain score and 29 to 88 on ASES score. There were no significant differences between the two groups (P > 0.05). The average range of motion of shoulder significantly increased in both groups at the final follow-up in comparison with the pre-operative time point. The evaluation at the final follow-up showed that 93% of the total subjects showed good or excellent results, and 95% showed satisfactory results from the procedure with regard to pain reduction and functional outcomes. Two cases of the 3 fair results were caused by acromioclavicular arthritis. Conclusion: It may be anticipated that arthroscopic rotator cuff repair and subacromial decompression may bring satisfactory post-operative outcomes in both PTRCT and FTRCT on pain relief and functional recovery. However, careful preoperative examination of the acromioclavicular joint is critical to avoid failures of these procedures.

제주지역 거시경제 전망모형을 이용한 정책효과 분석 (An Analysis on the Effect of Policy Using Macro-economic Forecasting Model of Jeju)

  • 고봉현
    • 한국산학기술학회논문지
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    • 제21권5호
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    • pp.458-465
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    • 2020
  • 본 연구의 목적은 제주지역 거시경제 전망모형을 이용하여 제주지역 사회의 중요한 정책에 대한 효과분석을 수행하는 것이다. 이를 위해, 본 연구에서는 기존의 Ko, et al.(2012) 모형을 본 연구의 목적에 맞게 확대·개편하였다. 연구의 주요 결과를 요약하면 다음과 같다. 첫째, 정책효과 분석을 위해, 2017년까지의 관련 통계자료와 데이터베이스를 갱신·점검하고, 새로운 대내외 정책변수들과 모듈(module)을 확대·추가함으로써 모형의 현실 설명력을 향상시켰다. 그리고 제주경제의 산업구조 변화에 따라 모형에서 설정된 산업구조를 보다 세분화시켰으며, 특히 케인즈 이론의 수요측면까지 모형에서 동시에 고려할 수 있도록 모형의 구조를 확장시켰다. 둘째, 모형의 평가에서는 구(舊)모형에 비해 본 연구의 모형에 대한 예측력이 우수한 것으로 평가되었다. 다만, 일부 내생변수에서 향후 지속적인 자료의 보완을 통해 보다 개선된 모형 개발의 시사점을 얻을 수 있었다. 셋째, 제2공항 건설에 따른 정책효과 분석결과, GRDP 1.25배, 고용 1.2배, 민간소비 1.48배, 투자 2.06배 증대되는 효과를 보이는 것으로 분석되었다. 그리고 경제성장률은 제2공항을 건설할 경우가 그렇지 않을 때보다 연평균 1.6%p 높은 것으로 분석되었다. 마지막으로 본 연구의 결과는 제주특별자치도의 정책의 사결정에 있어 직·간접적으로 활용될 수 있을 것으로 기대된다.

유역특성에 의한 합성단위도의 유도에 관한 연구 (Derivation of the Synthetic Unit Hydrograph Based on the Watershed Characteristics)

  • 서승덕
    • 한국농공학회지
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    • 제17권1호
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    • pp.3642-3654
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    • 1975
  • The purpose of this thesis is to derive a unit hydrograph which may be applied to the ungaged watershed area from the relations between directly measurable unitgraph properties such as peak discharge(qp), time to peak discharge (Tp), and lag time (Lg) and watershed characteristics such as river length(L) from the given station to the upstream limits of the watershed area in km, river length from station to centroid of gravity of the watershed area in km (Lca), and main stream slope in meter per km (S). Other procedure based on routing a time-area diagram through catchment storage named Instantaneous Unit Hydrograph(IUH). Dimensionless unitgraph also analysed in brief. The basic data (1969 to 1973) used in these studies are 9 recording level gages and rating curves, 41 rain gages and pluviographs, and 40 observed unitgraphs through the 9 sub watersheds in Nak Oong River basin. The results summarized in these studies are as follows; 1. Time in hour from start of rise to peak rate (Tp) generally occured at the position of 0.3Tb (time base of hydrograph) with some indication of higher values for larger watershed. The base flow is comparelatively higher than the other small watershed area. 2. Te losses from rainfall were divided into initial loss and continuing loss. Initial loss may be defined as that portion of storm rainfall which is intercepted by vegetation, held in deppression storage or infiltrated at a high rate early in the storm and continuing loss is defined as the loss which continues at a constant rate throughout the duration of the storm after the initial loss has been satisfied. Tis continuing loss approximates the nearly constant rate of infiltration (${\Phi}$-index method). The loss rate from this analysis was estimated 50 Per cent to the rainfall excess approximately during the surface runoff occured. 3. Stream slope seems approximate, as is usual, to consider the mainstreamonly, not giving any specific consideration to tributary. It is desirable to develop a single measure of slope that is representative of the who1e stream. The mean slope of channel increment in 1 meter per 200 meters and 1 meter per 1400 meters were defined at Gazang and Jindong respectively. It is considered that the slopes are low slightly in the light of other river studies. Flood concentration rate might slightly be low in the Nak Dong river basin. 4. It found that the watershed lag (Lg, hrs) could be expressed by Lg=0.253 (L.Lca)0.4171 The product L.Lca is a measure of the size and shape of the watershed. For the logarithms, the correlation coefficient for Lg was 0.97 which defined that Lg is closely related with the watershed characteristics, L and Lca. 5. Expression for basin might be expected to take form containing theslope as {{{{ { L}_{g }=0.545 {( { L. { L}_{ca } } over { SQRT {s} } ) }^{0.346 } }}}} For the logarithms, the correlation coefficient for Lg was 0.97 which defined that Lg is closely related with the basin characteristics too. It should be needed to take care of analysis which relating to the mean slopes 6. Peak discharge per unit area of unitgraph for standard duration tr, ㎥/sec/$\textrm{km}^2$, was given by qp=10-0.52-0.0184Lg with a indication of lower values for watershed contrary to the higher lag time. For the logarithms, the correlation coefficient qp was 0.998 which defined high sign ificance. The peak discharge of the unitgraph for an area could therefore be expected to take the from Qp=qp. A(㎥/sec). 7. Using the unitgraph parameter Lg, the base length of the unitgraph, in days, was adopted as {{{{ {T}_{b } =0.73+2.073( { { L}_{g } } over {24 } )}}}} with high significant correlation coefficient, 0.92. The constant of the above equation are fixed by the procedure used to separate base flow from direct runoff. 8. The width W75 of the unitgraph at discharge equal to 75 per cent of the peak discharge, in hours and the width W50 at discharge equal to 50 Per cent of the peak discharge in hours, can be estimated from {{{{ { W}_{75 }= { 1.61} over { { q}_{b } ^{1.05 } } }}}} and {{{{ { W}_{50 }= { 2.5} over { { q}_{b } ^{1.05 } } }}}} respectively. This provides supplementary guide for sketching the unitgraph. 9. Above equations define the three factors necessary to construct the unitgraph for duration tr. For the duration tR, the lag is LgR=Lg+0.2(tR-tr) and this modified lag, LgRis used in qp and Tb It the tr happens to be equal to or close to tR, further assume qpR=qp. 10. Triangular hydrograph is a dimensionless unitgraph prepared from the 40 unitgraphs. The equation is shown as {{{{ { q}_{p } = { K.A.Q} over { { T}_{p } } }}}} or {{{{ { q}_{p } = { 0.21A.Q} over { { T}_{p } } }}}} The constant 0.21 is defined to Nak Dong River basin. 11. The base length of the time-area diagram for the IUH routing is {{{{C=0.9 {( { L. { L}_{ca } } over { SQRT { s} } ) }^{1/3 } }}}}. Correlation coefficient for C was 0.983 which defined a high significance. The base length of the T-AD was set to equal the time from the midpoint of rain fall excess to the point of contraflexure. The constant K, derived in this studies is K=8.32+0.0213 {{{{ { L} over { SQRT { s} } }}}} with correlation coefficient, 0.964. 12. In the light of the results analysed in these studies, average errors in the peak discharge of the Synthetic unitgraph, Triangular unitgraph, and IUH were estimated as 2.2, 7.7 and 6.4 per cent respectively to the peak of observed average unitgraph. Each ordinate of the Synthetic unitgraph was approached closely to the observed one.

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앞으로 달리기와 뒤로 달리기 시 하지 커플링각 분석 (Analysis of the Lower Extremity's Coupling Angles During Forward and Backward Running)

  • 류지선
    • 한국운동역학회지
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    • 제16권3호
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    • pp.149-163
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    • 2006
  • The purpose of this study was to compare the lower extremity's joint and segment coupling patterns between forward and backward running in subjects who were twelve healthy males. Three-dimensional kinematic data were collected with Qualisys system while subjects ran to forward and backward. The thigh internal/external rotation and tibia internal/external rotation, thigh flexion/extension and tibia flexion/extension, tibia internal/external rotation and foot inversion/eversion, knee internal/external rotation and ankle inversion/eversion, knee flexion/extension and ankle inversion/eversion, knee flexion/extension and ankle flexion/extension, and knee flexion/extension and tibia internal/external rotation coupling patterns were determined using a vector coding technique. The comparison for each coupling between forward and backward running were conducted using a dependent, two-tailed t-test at a significant level of .05 for the mean of each of five stride regions, midstance(1l-30%), toe-off(31-50%), swing acceleration(51-70%), swing deceleration(71-90), and heel-strike(91-10%), respectively. 1. The knee flexion/extension and ankle flexion/extension coupling pattern of both foreward and backward running over the stride was converged on a complete coordination. However, the ankle flexion/extension to knee flexion/extension was relatively greater at heel-strike in backward running compared with forward running. At the swing deceleration, backward running was dominantly led by the ankle flexion/extension, but forward running done by the knee flexion/extension. 2. The knee flexion/extension and ankle inversion/eversion coupling pattern for both running was also converged on a complete coordination. At the mid-stance. the ankle movement in the frontal plane was large during forward running, but the knee movement in the sagital plane was large during backward running and vice versa at the swing deceleration. 3. The knee flexion/extension and tibia internal/external rotation coupling while forward and backward run was also centered on the angle of 45 degrees, which indicate a complete coordination. However, tibia internal/external rotation dominated the knee flexion/extension at heel strike phase in forward running and vice versa in backward running. It was diametrically opposed to the swing deceleration for each running. 4. Both running was governed by the ankle movement in the frontal plane across the stride cycle within the knee internal/external rotation and tibia internal/external rotation. The knee internal/external rotation of backward running was greater than that of forward running at the swing deceleration. 5. The tibia internal/external rotation in coupling between the tibia internal/external rotation and foot inversion/eversion was relatively great compared with the foot inversion/eversion over a stride for both running. At heel strike, the tibia internal/external rotation of backward running was shown greater than that of forward(p<.05). 6. The thigh internal/external rotation took the lead for both running in the thigh internal/external rotation and tibia internal/external rotation coupling. In comparison of phase, the thigh internal/external rotation movement at the swing acceleration phase in backward running worked greater in comparison with forward running(p<.05). However, it was greater at the swing deceleration in forward running(p<.05). 7. With the exception of the swing deceleration phase in forward running, the tibia flexion/extension surpassed the thigh flexion/extension across the stride cycle in both running. Analysis of the specific stride phases revealed the forward running had greater tibia flexion/extension movement at the heel strike than backward running(p<.05). In addition, the thigh flexion/extension and tibia flexion/extension coupling displayed almost coordination at the heel strike phase in backward running. On the other hand the thigh flexion/extension of forward running at the swing deceleration phase was greater than the tibia flexion/extension, but it was opposite from backward running. In summary, coupling which were the knee flexion/extension and ankle flexion/extension, the knee flexion/extension and ankle inversion/eversion, the knee internal/external rotation and ankle inversion/eversion, the tibia internal/external rotation and foot inversion/eversion, the thigh internal/external rotation and tibia internal/external rotation, and the thigh flexion/extension and tibia flexion/extension patterns were most similar across the strike cycle in both running, but it showed that coupling patterns in the specific stride phases were different from average point of view between two running types.

낙동강 하류의 수산 개발을 위한 기본 조사 2. 수온 및 수질 (FUNDAMENTAL STUDIES OF THE LOWER PART OF THE NAKTONG RIVER FOR FISHERIES EXPLOITATION 2. Temperature and Quality of the River Water)

  • 김인배
    • 한국수산과학회지
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    • 제3권1호
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    • pp.65-70
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    • 1970
  • 본 조사보고는 제1보에 이어서 낙동강 하류 구역의 3개 지점, 하단, 구포 및 삼랑진에서 1967년 5월부터 1968 년 6월에 이르는 기간 수온 관측과 수질의 물리 화학적 검사를 하고 그 결과를 보고하는 동시에 몇가지 고찰을 가하였다. Fig. 2에서 나타난 바와 같이 해양 수온의 영향을 강하게 받는 하단을 제외하면 3월까지의 평군 수온은 $10^{\circ}C$미만이고, 4월부터 5월 초중순까지근 대략 $10\~20^{\circ}C$ 범위이며, 그 후, 온수성 어류의 본격적인 생장수온인 $20^{\circ}C$ 이상을 유지한다. 그리하여 10월 초순 이후 $20^{\circ}C$ 이하로 강하하고, 12월부터 다시 $10^{\circ}C$ 이하로 내려간다. 오전 7시와 하오 4시외 수온차는 물이 정체하는 하구 지역인 하단에서는 월 평균차 $2.6\~6.8^{\circ}C$ 전평균 $4.6^{\circ}C$로서 대단히 크고, 보다 상류인 구포와 하단에서는 작다. 수온은 매일의 최저 최고 수온을 측정하여 그 변화상태를 파악해야 하천 생물의 관리에 유익한 자료로 쓰일 수 있다.

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임하 다목적댐 건설 후 주변지역 기후 및 작물생산력 변화 (Simulation of Local Climate and Crop Productivity in Andong after Multi-Purpose Dam Construction)

  • 윤진일;황재문;이순구
    • 한국작물학회지
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    • 제42권5호
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    • pp.579-596
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    • 1997
  • 1990년 임하 다목적댐 건설에 의해 경북 안동지역에 생성된 담수면적 28.7$\textrm{km}^2$의 임하호가 주변지역의 국지기후 및 주요 작물의 잠재생산력에 미친 영향을 구명하기 위해 임하호 주변 $30km\times 25km$ 지역을 대상으로 무인기상관측망을 구성, 5년간의 특별관측을 수행하였다. 수집된 자료를 토대로 담수전후 기후시나리오를 작성하고 이를 작물모형에 입력하여 최종 건물생산량을 추정한 바, 주요 결과는 다음과 같다. 1. 담수후 5년간 일최고기온은 담수 전보다 평균적으로 한후기 (10월~3월)에 상승하고 난후기에 하강하였으나, 예외적으로 6월과 7월에는 상승하였다. 일최저기온은 담수 전보다 평균적으로 난후기(4월~8월)에 하강하고 한후기에 상승하였다. 담수 전후 기온의 변화정도는 겨울철에 크고 여름철에 적었다. 2. 담수후 5년간 강수량은 담수 전보다 평균적으로 2, 3, 5, 7, 12월에 증가하였고 나머지 달에는 감소하였으나 연간 총강수량의 변화는 인정되지 않았다. 월별 일사량은 2, 6, 9월을 제외하고는 담수전에 비해 5% 가량 감소하였다. 3. 담수 전후 30년간씩의 벼 생육모의실험에서 대상지역내 27개 재배구역 중 담수에 의해 잠재수량의 변화가 인정되는 곳은 한 곳 뿐으로 담수전에 비해 정조 기준 4%의 증가를 보였다. 4. 담수 전후 30년간씩의 콩 생육모의실험에서 대상지역내 27개 재배구역 중 담수에 의해 잠재수량 감소가 인정되는 곳이 2개였으며 최대 감수율은 16%였다. 5. 담수 전후 30년간씩의 옥수수 생육모의실험에서 담수에 의해 옥수수의 잠재수량 감소가 인정되는 곳이 총 27개 중 6개였고 최대 감수율은 17%였다.. 또한 유수의 크기는 전 유수발달기를 통하여 항상 밀양 2003가 고시히카리보다 컸다. the canopies with more leaf mass, making MB the highest, HB the lowest, and DS in between. Relative humidity was over 90% in the night and dropped to 70% in the mid-afternoon, but vapor pressure within the canopy was highest at around 13:00 LST. Dew point depression was lowest and, combined with the temperature, the relative humidity was highest in HB. Mean period of wetting duration was in the order of DS>HB>MB, while the dew point depression was greatest in DS.ANCOVA, Pearson correlation을 이용하여 분석하였으며, 그 결과는 다음과 같다. 캠프 프로그램은 소아 당뇨병 환자의 자기 효능을 증진시키고 환자 역할 행위 이행을 높여주는데 효과적 이었다. 소아 당뇨병 환자의 자기 효능은 환자 역할 행위 이행과 순 상관 관계가 있어, 자기 효능이 증진될수록 환자 역할 행위 이행 정도가 높아졌다. 무조건 사주지 않는다(8.0%), 무조건 사준다(3.1%)로 식품광고에 나오는 식품 요구시 부모의 70.3%가 거절하는 것으로 나타났다. 거절 이유는 건강에 나쁘다는 것이 가장 큰 이유였으며 강남과 강북 어린이간에 유의적인 차이가 있었다(p<0.001). TV

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급성호흡곤란증후군 환자에서 Soluble Triggering Receptor Expressed on Myeloid Cells-1의 예후인자로서의 유용성 (Prognostic Utility of the Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Patients with Acute Respiratory Distress Syndrome)

  • 허진원;정훈;임채만;고윤석;홍상범
    • Tuberculosis and Respiratory Diseases
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    • 제65권4호
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    • pp.301-307
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    • 2008
  • 연구배경: Triggering receptor expressed on myeloid cells-1 (TREM-1)은 호중구와 단핵구의 표면에 표현되는 수용체로 호중구가 자극되면 표면에서 떨어져 수용체인 sTREM-1으로 존재하며 염증반응을 증폭시킨다. 본 연구는 호중구의 활성화가 중요한 병인인 급성호흡곤란증후군 환자의 기관지폐포세척액과 혈청에서 측정한 sTREM-1의 농도가 예후인자로서 유용성이 있는지 확인하고자 시행되었다. 방 법: 32명의 급성호흡곤란증후군 환자가 포함되었고 이 중 15명이 생존군, 17명이 사망군으로 분류되었다. 중증도 지표로 APACHE II score, Clinical Pulmonary Infection Score (CPIS)를 측정하였고, 기관지폐포세척액과 혈청에서 sTREM-1 농도를 측정하였고 중환자실 사망여부를 확인하였다. 결 과: 진단 시 급성호흡곤란증후군 환자의 혈청 내 sTREM-1의 농도는 사망군에서 생존군 보다 유의하게 상승되어 있었으나 ($54.3{\pm}10.3pg/ml$ vs. $22.7{\pm}2.3pg/ml$, p<.05) 기관지폐포세척액 내의 sTREM-1의 농도는 차이가 없었다. 혈청 내 sTREM-1의 농도는 급성호흡곤란증후군 환자의 예후를 예측할 수 있는 독립적인 인자(OR: 22.051, 95% CI: 1.780~273.146, p=0.016)이었고, 33pg/ml 경계로 분류 시 중환자실 사망률을 예측하는데 71%의 민감도와 93%의 특이도를 보였다. 결 론: 급성호흡곤란증후군 환자의 진단 당시 측정한 혈청 sTREM-1의 농도는 중요한 예후 인자로서 유용성이 있을 것으로 생각된다.