• Toxicological Research
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• 제27권4호
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• pp.247-251
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• 2011

To clarify whether inhibitory effect of estrogen on liver tumor is associated with cell proliferation, we investigated its role in diethylnitrosamine (DEN)-induced rat preneoplastic lesions, with time sequenced manners. F344 male rats (n = 90) were divided into three groups at 5 weeks of age. The mini-osmotic pumps providing a continuous infusion of DEN was implanted into the abdominal cavity of each animal in group 1, 2 and 3 at 6 weeks of age. To see the effect of estrogen, pellet containing 1 or 10 ${\mu}g$ of estradiol-3-benzoate (EB) was implanted subcutaneously in the animals of groups 2 or 3, respectively, one week prior to DEN treatment. Ten animals of each group were euthanized at 10, 14 and 18 weeks after DEN treatment. Liver tissues at each time point were fixed in 10% phosphate-buffered formalin and were processed and embedded in paraffin and 5 ${\mu}g$ sections mounted on a silanized slide. Glutathione S-transferase placental form (GST-P) positive foci and 5-bromo-2-deoxyuridine (BrdU) labeling cells were detected at each time point. Area of GST-P positive foci in DEN+EB 1 or 10 ${\mu}g$ group was significantly decreased compared to DEN alone at 14 weeks (p < 0.01 or p < 0.05, respectively) an at 18 weeks (p < 0.05 or p < 0.01, respectively). BrdU index in DEN+EB 1 or 10 ${\mu}g$ groups was significantly decreased compared to DEN alone at 14 weeks and at 18 weeks (p < 0.01). Taken together, we conclude that EB treatment decrease the DEN-induced liver preneoplastic lesions and this may be associated with decrease of cellular proliferation.

• 한국환경보건학회지
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• 제34권5호
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• pp.374-381
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• 2008

In this study, the factors affecting biological N and P removal using SND (simultaneous nitrification and denitrification) process were investigated and evaluated to examine the possibility of treating N and P through SND with NADH by surveying N and P traces in an aeration tank. Variations of $NH_4^+$-N+$NO_3^-$-N concentration were used to estimate the degree of SND in each point (P2, P3, P4, P5) of the aeration tank and these variations showed that denitrification efficiency in P2 (front zone), nitrification and denitrification efficiencies in P4 (middle zone) were 67%, 86% and 39%, respectively. When $PO_4^{-3}$-P concentration was analyzed in each point of the aeration tank, it was shown that $PO_4^{-3}$-P concentration coming into P2 was 1.25 mg/L, which increased to 2.22 mg/L by P release in P2 zone and then decreased to 0.74 mg/L by P uptake in P4. Consequently, we were able to estimate which high P removal efficiency observed in this study was caused by biological phosphorus removal. To determine the operating factors affecting effluent T-N, we analyzed the correlation among FN/M ratio, C/N ratio, Temp., SRT etc and these results showed that the correlation among FN/M ratio, C/N ratio and Temp was not high. However, the relationship of SRT and other parameters (effluent $NH_4^+$-N and effluent BOD) and the short SRT could have an affect on effluent $NH_4^+$-N and so effluent BOD could be increased. Thus, SRT operation should be controlled over 10 days. The results for analyzing the correlation between SRT and influent $NO_3^-$-N in order to investigate the operating factors affecting effluent T-P showed that T-P or $PO_4^{-3}$-P was not highly correlation with SRT, whereas $PO_4^{-3}$-P concentration increased along with increasing $NO_3^-$-N concentration into P2. Based on these results, we concluded, using regression analysis (R2=0.97), that effluent $PO_4^{-3}$-P concentration depends on $NO_3^-$-N concentration into P2.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권2호
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• pp.152-161
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• 2007

This study was conducted to patients visited oral maxillo-facial surgery, KNUH and the purpose of the study was to assess skeletal and dento-alveolar stability after surgical-orthodontic correction treated by skeletal Class III malocclusion patients with open bite versus non-open bite. This retrospective study was based on the examination of 40 patient, 19 males and 21 females, with a mean age 22.3 years. The patients were divided into two groups based on open bite and non-open bite skeletal Class III malocclusion patients. The cephalometric records of 40 skeletal Class III malocclusion patients (open bite: n = 18, non-open bite: n = 22) were examined at different time point, i.e. before surgery(T1), immediately after surgery(T2), one year after surgery(T3). Bilateral sagittal split ramus osteotomy was performed in 40 patients. Rigid internal fixation was standard method used in all patient. Through analysis and evaluation of the cephalometric records, we were able to achieve following results of post-surgical stability and relapse. 1. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in maxillary occlusal plane angle of pre-operative stage(p>0.05). 2. Mean vertical relapses of skeletal Class III malocclusion patients with open bite were $0.02{\pm}1.43mm$ at B point and $0.42{\pm}1.56mm$ at Pogonion point. In skeletal Class III malocclusion patients with non-open bite, $0.12{\pm}1.55mm$ at B point and $0.08{\pm}1.57mm$ at Pogonion point. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in vertical relapse(p>0.05). 3. Mean horizontal relapses of skeletal Class III malocclusion patients with open bite were $1.22{\pm}2.21mm$ at B point and $0.74{\pm}2.25mm$ at Pogonion point. In skeletal Class III malocclusion patients with non-open bite, $0.92{\pm}1.81mm$ at B point and $0.83{\pm}2.11mm$ at Pogonion point. There was no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in horizontal relapse(p>0.05). 4. There were no significant statistical differences between open bite and non-open bite with skeletal Class III malocclusion patients in post-surgical mandibular stability(p>0.05). and we believe this is due to minimized mandibular condylar positional change using mandibular condylar positioning system and also rigid fixation using miniplate 5. Although there was no significant relapse tendency observed at chin points, according to the Pearson correlation analysis, the mandibular relapse was influenced by the amount of vertical and horizontal movement of mandibular set-back(p=0.05, r>0.304).

• Nonlinear Functional Analysis and Applications
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• 제26권1호
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• pp.13-33
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• 2021

The aim of this paper is to establish common fixed point theorems under generalized (ψ - ϕ)-weak contractions in the setting of complete S-metric spaces and we support our result by some examples. Also an application of our results, we obtain some fixed point theorems of integral type. Our results extend Theorem 2.1 and 2.2 of Doric [5], Theorem 2.1 of Dutta and Choudhury [6], and many other several results from the existing literature.

• 한국농공학회논문집
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• 제60권1호
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• pp.31-36
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• 2018

A rainwater harvesting device was developed for runoff flow harvesting in a small stream or channel and its performance was evaluated in small fields. The rainwater harvesting device has slits on its side of cylindrical volume in 15 cm diameter and 70 cm length, which is designed to increase its water flow harvesting capacity. The maximum collectable water quantity was about 0.0022 ton/sec (130 L/min). Rainwater harvesting device were installed in two locations (P1, P2). P1 is a point for rainfall runoff flow harvesting. P2 is a point for ordinary flow harvesting. During this study, total rainfall depth was 334.5 mm. Runoff of 1,722 ton and 7,984 ton occurred in P1 and P2, and 273 ton and 125 ton were collected by this rainwater harvesting device. Harvesting efficiency was calculated as 15.85 % and 1.57 % in P1 and P2. Clogging of screen filter media in the cylinder due to soil and suspended solids has lowered the harvesting efficiency. However, it was possible to harvest 30 ton/month of rainwater harvesting and it is expected that it will help to solve short-term water shortage.

• Restorative Dentistry and Endodontics
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• 제13권2호
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• pp.207-220
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• 1988

The purpose of this study was to measure roughness on the polished surfaces of composite resin, and was to observe the polished surfaces under Scanning Electron Microscope. The surface roughness tester (Surfcom 700A Semitsu Profilometer Tokyo. Japan) was used to measure roughness of polished surfaces. In this study, 4 brands of composite resin were examined, Pyrofil bond anterior Bell-Feel anterior Clearfil F II and Microrest A.P. White point, Silicone point, Super snap, and Sof-Lex medium disc as cutting instrument, and celluloid matrix were used. The results obtained were as follows. 1) The celluloid matrix produced the smoothest surfaces. 2) Microrest composite resin had smoother surface than any other composite resins after polishing. 3) The values of surface roughness made by White point, Silicon point and Super snap were similar. 4) The surfaces made by Sof-Lex medium disc was smoother than the surfaces made by any other polishing instruments.

• Physical Therapy Rehabilitation Science
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• 제3권2호
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• pp.142-147
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• 2014

Objective: This study aims to investigate high energy and low energy extracorporeal shockwave therapy (ESWT) and which one is more effective for shoulder pain. Design: Single blind randomized controlled trial. Methods: Fifty two subjects with upper trapezius (UT) trigger point (TrP) participated in this study. They were allocated to high energy (n=26) and low energy group (n=26). This study applies ESWT and investigates the changes of pressure pain threshold (PPT) and visual analogue scale (VAS). The high and low energy groups received focused piezo electric type ESWT 4 Hz, 1,000 pulses and 0.351 and $0.092mJ/mm^2$ respectively. Outcome measures of PPT and pain was measured by algometer and pain VAS. These measurements were performed before and after treatment. Results: The PPT value was significantly increased in both groups after treatment (p<0.05) and VAS scores were significantly decreased after treatment in both groups (p<0.05). However, there were no significant differences between groups. Conclusions: ESWT is an effective treatment for the application of the UT TrP. Although there were significant effects of extracorporeal shock wave therapy on PPT and VAS scores, there were no signficant differences between high and low energy extracorporeal shock wave therapy.

• KSBB Journal
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• 제10권1호
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• pp.1-8
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• 1995

냉통고기풀 또는 수산연제품 등의 수산가공품 제조시 수세공정에 의해 폐액 중으로 많은 수용성 단백질과 지질성분이 유출되고 있는데, 이로 인하여 폐수의 BOD 및 COD값이 상승되어 해양의 오염과 연안의 적조현상을 일으키는 원인이 되고 있다. 따 라서, 본 연구에서는 해양오염 방지 빛 미이용 자원 의 개발이라는 두 측면에서 수세폐액 중에 함유되어 있는 수용성 단백질을 등전점 pH이동침전법에 의해 최적으로 회수하는 조건을 규명하였고, 아울러 그 회수단백질의 이용가능성 타진을 위해 기초척인 성 분 분석도 행하였다. $\circled1$ 수세폐액 중의 수용성 단백질을 회수하기 위한 방법으로서 여러 가지 등전점 응집법 중 산이통법이 효율적이었다. 즉 수세폐액을 먼저 pH 2.5~3.0으 로 낮춘 후 pH 6.5~7.5로 재조절하여 원심분리한 것이 높은 단백질 회수율을 나타내였다. 한편, 폐액 내 잔존지방은 산이통 처리후 대부분 부유하여서 그 상충수를 따라 부어내어 유분리기로 쉽게 수거가능 하므로 본 처리 장치로써 잔존단백질과 지방을 동시 회수할 수가 있다. $\circled2$ 최척처리조건에서 회수한 단백질구분의 수분과 단백 질 함량은 80.6 및 14.4 % 였다. 한편, 회수단백 질구분의 VBN함량은 9.6mgj100g로서 선도가 양 호하였으며, 구성아미노산 중 lysine 등 필수아미노 산이 여전히 많은 비율로 존재해 있어 영향학적으로 도 손색이 없었다. 이상의 결과로 미루어 보아 냉통고기풀이나 어묵 의 제조공정 중에 나오는 수세폐액으로부터 수용성 단백질 벚 유지를 통전점침전법의 한 변형인 산이통 법으로 간단히 재회수할 수 있음을 얄 수 있었다. 그래서 이들 성분의 재회수로 수산가공공장폐액에 의 한 하천의 오염을 근본적으로 막을 수 있음은 물론 이고 수산가콩폐기물의 완전 식량화의 가능성도 찾 아볼 수 있게 되었다고 판단되어진다.

• 한국안전학회지
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• 제35권3호
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• pp.105-115
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• 2020

This study compares the difference of fit factors (FF) and visual acuity according to masks and eyeglasses preferences for 54 participants. We the precautions and behaviors of discomfort when wearing masks of eyewear wearers. Contact lens discomfort and priority action of complaints was investigated Glasses fitting factors is Optical Center Height(OH), Vertex Distance(VD) and Pantoscopic Angle(PA). We measured those factors and expressed by the ratio of standard point and change point. Quantitative fit factor was measured by Portacount Pro+ 8038. Also, we selected to 6 exercises among 8 exercises OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The pass/ fail criterion of FF was set at 100. Visual acuity(VA) test chart is developed by Chunsuk Han was used, Descriptive statistics was performed. Descriptive statistics(SAS ver 9.2), it is used geometric means, Wilcoxon analysis(P=0.05) When wearing the mask preferentially, fit factor(FF) was high according to the step of glasses fitting parameter. on the other hand, when the glasses first choice, the visual acuity(VA) was high. there was no significant difference. In the case of fit factor (FF), mask first choice/ glasses first choice is OH (p=0.671/ p=0.332), VD (p=0.602/ p=0.571) and PA (p=0.549/ p=0.607). Visual acuity (VA), mask first choice/ glasses first choice is OH (p=0.753/ p=0.386), VD (p=0.815/ p=0.557) and PA (p=0.856/ p=0.562). The workers of workplace and office chose glasses but occupational health workers and students chose mask. In case of discomforts, it was suggested to remove the mask and tolerate discomforts. The main discomforts and usual action of lens were dryness, hyperemia, foreign body sensation, ophthalmodynia, decreased vision and glasses wearing. Therefore, it is necessary to develop a mask wearing method education program considering glasses fitting and develop a hybrid model that minimizes inconvenience when wearing glasses and a mask at the same time.

• 한국전자통신학회논문지
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• 제6권2호
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• pp.157-162
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• 2011

국제전기통신연합(ITU)은 ITU-R을 통해 현재 많은 서비스가 이루어지고 있는 방송 및 통신 분야에서 다양한 전파 환경에 적용할 수 있는 각각의 예측 모델을 권고하고 있다. 각 전파예측모델은 예상되는 많은 채널환경의 차이를 보완하기 위한 절차를 통해 수정되며, 전파예측 판단을 위한 평가 기준으로 준비된다. 본 연구에서는 방송 환경에 적합한 점대 영역(Point-to-Area) 모델, ITU-R Rec. P.1546-3에서, 송신국 스펙이 고려되어 있지 않은 파라미터를 보충함으로써, 각 송신국에서의 요소를 고려한 실질적인 전파 예측 모델의 구현이 가능하도록 하였다.