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Protective Effects of Lacticaseibacillus rhamnosus IDCC3201 on Motor Functions and Anxiety Levels in a Chronic Stress Mouse Model

  • Jae Gwang Song;Daye Mun;Bomi Lee;Minho Song;Sangnam Oh;Jun-Mo Kim;Jungwoo Yang;Younghoon Kim;Hyung Wook Kim
    • Food Science of Animal Resources
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    • v.43 no.6
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    • pp.1044-1054
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    • 2023
  • Growing evidence indicates a crucial role of the gut microbiota in physiological functions. Gut-brain axis imbalance has also been associated with neuropsychiatric and neurodegenerative disorders. Studies have suggested that probiotics regulate the stress response and alleviate mood-related symptoms. In this study, we investigated the effects of the probiotic Lacticaseibacillus rhamnosus IDCC3201 (L3201) on the behavioral response and fecal metabolite content in an unpredictable chronic mild stress (UCMS) mouse model. Our study shows that chronic stress in mice for three weeks resulted in significant changes in behavior, including lower locomotor activity, higher levels of anxiety, and depressive-like symptoms, compared to the control group. Metabolomic analysis demonstrated that disrupted fecal metabolites associated with aminoacyl-tRNA biosynthesis and valine, leucine, and isoleucine biosynthesis by UCMS were restored with the administration of L3201. Oral administration of the L3201 ameliorated the observed changes and improved the behavioral alterations along with fecal metabolites, suggesting that probiotics play a neuroprotective role.

A comparative study of the Dunhuang Costume on the Folk Song's words in Dnag's period of the China. (중국.고대 돈황가중의 복식 연구)

  • 김은주
    • Journal of the Korean Society of Costume
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    • v.22
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    • pp.159-176
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    • 1994
  • This study's purpose is to find the ancient costume of the folk song's words on Dunhuang manuscripts in the background wass-carvings sculptures and several art works. Dunhuang had played the part of major route between ancient China and Europe. It is located on kam-suksong the west of China. 1. In the aspect of costume arrangement hair Styling is represented by Naegagyo, Wangyesa, Kyongburak, Bonkwyun, Pogurak, Chonsonja, Namgaja, Tongson-ga, Ojesa, Chanboja in Dunhuang manuscripts. tugue is sim-ilar to Sabyokkwanja in Naegagyo as of that time these kinds of Kwan-ja was very popular. It was told that emperor's wife concubine and maid of honor would wear kwnaja favorably. And the kinds of Tugeu is PuyongKwyunkye, Aangunkye, Chunkye from Kyuwanjon except Sangunkye, Ounkye in Dunhuangsa. 2. Jangdaegy is guoted from Kyuw-anjon -A series of the chinese history book-tells us about women's make-up . The narmes of make-up are Hongjang Unjan--g, Yiljang chwejang, Tam-ajang Murgjang, Sanagjang, Light-make up are referred in Naegagyo is included as packjang Besides we can find other make-up skills Huphwaro and Rujang from the Kaewonch onbon-wisa which was Yangkwibi's episodes. We can find the a corpus of song's words about cosmetic custom in Kor-ea. Which is 'Haecho' folk song in the souther-en costal regions 'Jinggum' folk song in Kim-hae regions and so on.... It's words is similar to Dunhuangsa in China. 3. Bichun inherited to China with India Bud-dism art in the middle of Dunhuang wall-pain-tings is one of the important Buddist saint. Sometimes it is painted with Giakchun Its arms of fly-dnacing in heaven with colored belt on body has almost the form of play on the musical instrument, We can see seasily the form in the painting of Buddist ser-mon. It was progressed and changed with the background of chinese traditional culture. When Dang's period came the color was chan-ged lighting dark blue has rhythmical and viv-id power of life. 4. Among the corpus of song's words which express the singers' system and rites of their tradition or habits. Dunhuang manuscripts des-cribes on behalf of the folk song's words in tra-ditional costume. This is following: (1) Naegagyo o sabyokwanja o Chyrasam o Rashang (2) Wangyesa o Sokryugun o Costume for fisher man (3) Bungajang of the chanboja o Ajang (4) Pongkwyun o Chongui (5) Tongsongs o Junofore (6) Namgaja o thin-Rasam (7) Yuchungnang o Hongsam o Sokryugun : The color of red costume (8) Kyongburak o Hongrasam o Sokryugun : Costume for charming woman Therefore traditional costume could be extracted according to the Dunhuang folk song's words out of culture such as learning rit-es three-obedience four-virtues and in-struction. As the same time it reflects ancient China's characteristics directly. I would endeavor to development for the history of the costume furher creative design and participat-ed in research activity with concerns forward continuously.

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A Study on the Effects of the Breath Efficiency & Lung Capacity Improvement Using Recorder Playing Focused on Breath Training (리코더 연주를 통한 뇌졸중 노력성 폐활량과 호흡 효율성 향상 연구)

  • Choi, Sung Joo
    • Journal of Music and Human Behavior
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    • v.4 no.1
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    • pp.31-46
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    • 2007
  • The purpose of the study was to improve the efficiency of Breath & Forced Vital Capacity(FVC) of Stroke Patients Using Record Playing Focused on Breath Training. The Training of Forced Vital Capacity(FVC) is focused on trunk muscles reinforce for Breathing. So the study tried to play Recorder for reinforcing FVC. The play included the two parts. One was for solo play, the other was play in concert base on solo play using Korea country song, Arirang. The Recorder play used abdominal breath, Pursed-lip & Paced methods. The course of play included Long Tone, Staccato, Crescendo, Decrescendo and throughout the course we tried to improve the efficiency & Quantity of breathe. Experiment performed at Social welfare institute for the old. They played & checked FVC, $FEV_1$, $FEV_1/FVC$ before & after breathe 19 times for 6 weeks using Spirovit SP-1, Schiller. After experiment we performed statical process(p<0.05) using statical Package software. The findings were as follows: Analysis for Experiment showed the numerical Value of increasing Of FVC, $FEV_1$, $FEV_1/FVC$. Increasing Percentage of Measured/Predicted FVC, $FEV_1$ (or calculated based on theory) ration was 25%, 13% and Quantity of FVC, $FEV_1$ 35%, 40%. Also $FEV_1/FVC$ Ratio(showed efficiency of breathe) raised 13%. And experiment data was confirmed by statical process. The experiment data was valuable under p<0.05. In Conclusion we think the results of experiment showed the efficiency of Music therapy for Breathe(FVC, $FEV_1$, $FEV_1/FVC$) reinforce.

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Synthesis of Nanoparticles via Surface Modification for Electronic Applications

  • Lee, Burtrand I.;Lu, Song-Wei
    • Proceedings of the Korea Association of Crystal Growth Conference
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    • 2000.06a
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    • pp.35-58
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    • 2000
  • The demand for sub-micrometer or nanometer functional ceramic powders with a better suspension behavior in aqueous media in increasing. Redispersible barium titanate (BT) nanocrystals, green light emitting Mn2+ doped Zn$_2$SiO$_4$ and ZnS nanoparticle phosphors were synthesized by a hydrothermal method or chemical precipitation with surface modification. The nanoparticle redispersibility for BT was achieved by using a polymeric surfactant. X-ray diffraction(XRD) results indicated that the BT particles are of cubic phase with 80 nm in size. XRD results of zinc silicate phosphor indicate that seeds play an important role in enhancing the nucleation and crystallization of Zn$_2$SiO$_4$ crystals in a hydrothermal condition. This paper describes and discuss the methods of surface modification, and the resulting related properties for BT, zinc silicate and zinc sulfide.

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The Effects of Personality and Stress of Railway Drivers on Job Satisfaction and Accidents (기관사의 성격과 스트레스가 직무만족 및 사고에 미치는 영향)

  • Shin, Tack-Hyun;Song, Sung-Tae
    • Proceedings of the KSR Conference
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    • 2011.05a
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    • pp.1023-1030
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    • 2011
  • The purpose of this article is to find out and analyze the diverse factors that are incurring stress to the railway drivers, and to depict the relationship among personality, job stress, job satisfaction, and accidents. To attain this purpose, the authors designed the questionnaire based on in-depth interview, scrutinized the factors of stressors, and statistically tested the study themes on the moderating effects of Personality Factors such as Locus of Control, Self-Efficacy, and Organization-Based Self Esteem on the relationship between Job Stressors and Job Satisfaction/Accidents, for the 212 samples received from KORAIL, Seoul Metro, and Seoul Metropolitan Rapid Transit. Resultedly, one of the findings indicate that certain aspects of a driver's personalities, as measured by locus of control, self-efficacy, and organization-based self esteem play important roles in predicting the level of job satisfaction, job stress and accidents.

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Bending behavior of aluminum foam sandwich with 304 stainless steel face-sheet

  • Yan, Chang;Song, Xuding
    • Steel and Composite Structures
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    • v.25 no.3
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    • pp.327-335
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    • 2017
  • To gain more knowledge of aluminum foam sandwich structure and promote the engineering application, aluminum foam sandwich consisting of 7050 matrix aluminum foam core and 304 stainless steel face-sheets was studied under three-point bending by WDW-T100 electronic universal tensile testing machine in this work. Results showed that when aluminum foam core was reinforced by 304 steel face-sheets, its load carrying capacity improved dramatically. The maximum load of AFS in three-point bending increased with the foam core density or face-sheet thickness monotonically. And also when foam core was reinforced by 304 steel panels, the energy absorption ability of foam came into play effectively. There was a clear plastic platform in the load-displacement curve of AFS in three-point bending. No crack of 304 steel happened in the present tests. Two collapse modes appeared, mode A comprised plastic hinge formation at the mid-span of the sandwich beam, with shear yielding of the core. Mode B consisted of plastic hinge formation both at mid-span and at the outer supports.

INJECTIVE COVERS OVER COMMUTATIVE NOETHERIAN RINGS OF GLOBAL DIMENSION AT MOST TWO II

  • KIM, HAE-SIK;SONG, YEONG-MOO
    • Communications of the Korean Mathematical Society
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    • v.20 no.3
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    • pp.437-442
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    • 2005
  • In studying injective covers, the modules C such that Hom(E, C) = 0 and $Ext^1$(E, C) = 0 for all injective module E play an important role because of Wakamatsu's lemma. If C is a module over the ring k[[x, y]] with k a field, the class of these modules C contains the class $\={D}$ of all direct summands of products of modules of finite length ([3, Theorem 2.9]). In this paper we show that every module over any commutative ring has a $\={D}$-preenvelope.

Single-molecule fluorescence measurements reveal the reaction mechanisms of the core-RISC, composed of human Argonaute 2 and a guide RNA

  • Jo, Myung Hyun;Song, Ji-Joon;Hohng, Sungchul
    • BMB Reports
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    • v.48 no.12
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    • pp.643-644
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    • 2015
  • In eukaryotes, small RNAs play important roles in both gene regulation and resistance to viral infection. Argonaute proteins have been identified as a key component of the effector complexes of various RNA-silencing pathways, but the mechanistic roles of Argonaute proteins in these pathways are not clearly understood. To address this question, we performed single-molecule fluorescence experiments using an RNA-induced silencing complex (core-RISC) composed of a small RNA and human Argonaute 2. We found that target binding of core-RISC starts at the seed region of the guide RNA. After target binding, four distinct reactions followed: target cleavage, transient binding, stable binding, and Argonaute unloading. Target cleavage required extensive sequence complementarity and accelerated core-RISC dissociation for recycling. In contrast, the stable binding of core-RISC to target RNAs required seed-match only, suggesting a potential explanation for the seed-match rule of microRNA (miRNA) target selection.

강제된 정보시스템 사용환경에서 결과기대가 사용활동에 미치는 영향에 관한 연구;사회인지이론의 관점

  • O, Song-U;Gwak, Gi-Yeong
    • 한국경영정보학회:학술대회논문집
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    • 2007.11a
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    • pp.123-128
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    • 2007
  • It has been argued that Enterprise systems (ES) implementations are overshadowed by a high failure rate despite their promised benefits. One of the commonly cited reasons for ES implementation failures in the context of mandatory use is end-user's unwillingness or sabotage to adopt or use systems. Considering that the appropriate management of expectations may play an important role in making positive behavior toward newly implemented systems, this study examines the effect of outcome expectations on the system use activity in the mandatory use context of information systems from the Social Cognitive Theory perspective. Structural equation model analysis using LISREL 8.7 provides significant support for the proposed relationships. The empirical results suggest that outcome expectations and user satisfaction have positive effects on system use activity conceptualized by immersion, reinvention, and learning. Theoretical and practical implications of the study shed some light on how to improve system use activity in the mandatory use context of information systems.

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Surveillance of wild birds for avian influenza virus in Korea (야생조류에 대한 조류인플루엔자 예찰의 중요성과 연구 동향)

  • Lee, Dong-Hun;Song, Chang-Seon
    • Korean Journal of Veterinary Research
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    • v.53 no.4
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    • pp.193-197
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    • 2013
  • Avian influenza viruses (AIV) have been isolated from a wide range of domestic and wild birds. Wild birds, predominantly ducks, geese and gulls form the reservoir of AIV in nature. The viruses in wild bird populations are a potential source of widespread infections in poultry. Active surveillance for AIV infection provides information regarding AIV distribution, and global AIV surveillance can play a key role in the early recognition of highly pathogenic avian influenza (HPAI). Since 2003 in Korea, there have been four H5N1 HPAI outbreaks caused by clade 2.5, 2.2 and 2.3.2. Therefore, improvement of AIV surveillance strategy is required to detect HPAI viruses effectively. This article deals with the major events establishing the role of wild birds in the natural history of influenza in Korea. We highlighted the need for continuous surveillance in wild birds and characterization of these viruses to understand AIV epidemiology and host ecology in Korea.