• Title/Summary/Keyword: platelets

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Functional Polymer Thin Films based on the Layer-by-Layer Deposition

  • Char, Kook-Heon
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.192-192
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    • 2006
  • Organic/organic and organic/inorganic multilayer films composed of organic polyelectrolytes (PE) and inorganic nanoparticles/platelets were prepared from the layer-by-layer (LbL) deposition using both spinning and dipping. The difference in both LbL methods is quantitatively compared in terms of internal layer ordering and physical properties of the multilayered films. Additionally, we suggest that the patterned multilayer films can be easily prepared by the combination of the spin SA and the lift-off method. Freestanding films were also prepared with the LbL deposition on low energy substrates, which allows the detailed analysis of composition within the films. Other LbL thin films prepared with block copolymer micelles will be discussed.

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Migration of Nanoclay in Immiscible Polymer Blends

  • Kim, Yong-Kyoung;Ahn, Kyung-Hyun;Lee, Seung-Jong;Hong, Joung-Sook
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.366-366
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    • 2006
  • Five sandwiched multilayers consisting of PBT(Polybutyleneterephthalate), PS(Polystyrene) and clay were prepared to investigate the migration mechanism of clay in the polymer blend system. Rheometry (RMS800) was used to apply well-defined shear on the above multilayer samples in order to well understand dominant factors controlling the migration. Applied shear force was enough to move clay tactoids to the interface, if either long time or high shear was available, but it was not sufficient to separate into individual platelets of clay. The morphology evolution was subsequently studied in term of scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HR-TEM), respectively.

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Precipitation In Inconel 718 Alloy

  • Park, Hyung-Sup;Park, Ju
    • Nuclear Engineering and Technology
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    • v.4 no.3
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    • pp.203-213
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    • 1972
  • The precipitation sequence of Inconel 718 alloy, aged at $760^{\circ}C$ for times up to 200 hr, has been studied by means of electron microscopy and X-ray diffraction methods. The dominant hardening phase was identified as the metastable, body-centered tetragonal $Ni_3Nb$ Phase in the morphology of platelets. The other phases identified in the aging sequence were (Nb, Ti)C and the stable acicular phase of orthorhombic $Ni_3Nb.$ The observations were made on the interaction of dislocations with the precipitates in the underaged condition. The shearing of the precipitates and the planar defects, e.g., stacking faults on i1101 planes of the intermetallic phase, were observed.

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Constituents of Euphorbia milii

  • YunChoi, Hye-Sook;Jin, Jing-Ling;Hong, Sung-Won;Lee, Yong-Yook;Lee, Jo-Hyung
    • Natural Product Sciences
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    • v.9 no.4
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    • pp.270-272
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    • 2003
  • The methanol extract of Euphorbia milii exhibited strong inhibitory effect on platelet aggregation in the cource of our search for anti-platelet component from succulent plants. Two components, components 1 and 2 were isolated from this plant. 1 was the mixture of 72% of 1-octacosanol (1a) and 28% of 1-triacontanol (1b), and 2 was identified as ${\beta}-sitosterol$. 2 ($IC_{50}$: $195\;{\mu}M$, and $170\;{\mu}M$ respectively) was about two fold stronger than ASA ($IC_{50}$: $420\;{\mu}M$ and $340\;{\mu}M$ respectively) on both collagen and U46619 induced aggregation, while the effect of 1 to platelets was negligible.

Experimental Studies on the Effects of Ferric Oxide (철액수(鐵液水)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(然究))

  • Jang, Hyun Jin
    • Journal of Sasang Constitutional Medicine
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    • v.3 no.1
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    • pp.173-183
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    • 1991
  • These studies were conducted about the effects of Ferric oxide in the aspect of the basic pharmacology through experimental animals with the investigation of its clinical effects on oriental medical literatures of Ferric oxide. The results were as follows: 1. The analgenic effects induced by acetic acid were significant. 2. The anticonvulsive effects induced by ECT unit were significant. 3. The sedative effects in Rotor rod method were significant. 4. The number of platelets was increased but not significantly. 5. Prothrombin time was decreased significantly. 6. Fibrinogen was increased but not significantly. 7. The degree of concentration of FDP was decreased significantly. According to the above results, it is considered that Ferric oxide retains effectiveness on the treatment of cerebral stroke.

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Effects of Intaking of Red Ginseng Products on Human Platelet Aggregation and Blood Lipids (홍삼류의 섭취가 사람 혈소판의 응집반응 및 혈중 지질에 미치는 영향)

  • 이정희;박화진
    • Journal of Ginseng Research
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    • v.22 no.3
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    • pp.173-180
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    • 1998
  • Thrombogenesis and atherosclerosis are mainly caused by platelet aggregation, blood coagulation, and hyperlipidemia. Platelet aggrelation, activated platelet thromboplastin time (APTT) were measured as indexes of blood coagulation and lipid contents in the subjects who have taken red ginseng products (e.g. water extract, tea, drink etc.) for 4 to 5 years. The platelet aggregation in the red ginseng-taking group was significantly decreased, as compared with the non-red ginseng-intaking group, when platelets were stimulated by 100 $\mu\textrm{g}$/ml of collagen (P<0.01). The atherogenic index and the ratio of triglyceride to HDL-cholesterol in blood, the risk factors of atherosclerosis, were decreased in the subjects of ginseng group, compared with that in control group. APTT was also prolonged to greater extent in ginseng group than in control group. These results suggest that long-term intake of ginseng products may help to prevent the risks of thrombogenesis and atherosclerosis.

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Inherited Macrothrombocytopenia in a Cavalier King Charles Spaniel

  • Kim, Hyo-jin;Choi, Seok-jin;Kim, Seung-Gon;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.34 no.4
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    • pp.272-274
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    • 2017
  • A 1-year-old intact male Cavalier King Charles Spaniel was presented with a ruptured anal sac. On routine preanesthetic screening tests for surgical resection, the thrombocytopenia was observed by an impedance-type autoanalyzer. A peripheral blood smear was used as a follow-up test and giant platelets were seen on the smear. DNA assay of this patient confirmed that the cause of the platelet abnormalities in this patient was genetic mutation. To our knowledge, this is the first case report of macrothrombocytopenia confirmed based on the DNA assay results, in a Cavalier King Charles Spaniel in Korea.

Finite element based modeling and thermal dynamic analysis of functionally graded graphene reinforced beams

  • Al-Maliki, Ammar F.H.;Ahmed, Ridha A.;Moustafa, Nader M.;Faleh, Nadhim M.
    • Advances in Computational Design
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    • v.5 no.2
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    • pp.177-193
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    • 2020
  • In the present research, dynamic analysis of functionally graded (FG) graphene-reinforced beams under thermal loading has been carried out based on finite element approach. The presented formulation is based on a higher order refined beam element accounting for shear deformations. The graphene-reinforced beam is exposed to transverse periodic mechanical loading. Graphene platelets have three types of dispersion within the structure including uniform-type, linear-type and nonlinear-type. Convergences and validation studies of derived results from finite element approach are also presented. This research shows that the resonance behavior of a nanocomposite beam can be controlled by the GPL content and dispersions. Therefore, it is showed that the dynamical deflections are notably influenced by GPL weight fractions, types of GPL distributions, temperature changes, elastic foundation and harmonic load excitation frequency.

The Effects of Astragali Radix on Cyclophosphamide-induced Leucopenia (황기(黃芪) 투여시기가 Cyclophosphamide 유발 흰쥐의 백혈구감소증에 미치는 영향)

  • Chang, Jae-Min;Ko, Seong-Gyu;Shin, Yong-Cheol
    • Journal of Society of Preventive Korean Medicine
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    • v.10 no.1
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    • pp.13-32
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    • 2006
  • In order to indentify the effect of Astragali Radix(A.R) on cyclophosphamide(C.Y) induced leukopenia, A.R. extracts(EAR) were treated to mice orally, and blood sampling was done by periods. For the in vivo experiments, mice were divided into 4 groups, which treated EAR before, or after C.Y injection, or both, or none. Rapid normalization in the peripheral blood count of WBC, neutrophils, lymphocytes, RBC, and platelets observed in every EAR treated group regardless of the treatment periods of EAR. These studies suggest that, A.R. premedication can be effective in protection of bone marrow suppression during anticancer therapy.

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Formation of Ti-B-N-C Ceramic Composite Materials via a Gas-Solid Phase Reaction

  • Yoon, Su-Jong
    • Korean Journal of Materials Research
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    • v.16 no.1
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    • pp.50-57
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    • 2006
  • Phase mixtures of Titanium boride, nitride, and carbide powder were produced by the reduction of a mixture of titanium and boron oxides with carbon via a gas-solid phase reaction. Boron oxides produce a vapour phase or decompose to a metal sub-oxide gaseous species when reduced at elevated temperature. The mechanism of BO sub-oxide gas formation from $B_2O_3$ and its subsequent reduction to titanium diboride for the production of uniform size hexagonal platelets is explained. These gaseous phases are critical for the formation of boride, nitride and carbide ceramics. For the production of ceramic phase composite microstructures, the nitrogen partial pressure was the most critical factor. Some calculated equilibrium phase fields has been verified experimentally. The theoretical approach therefore identifies conditions for the formation of phase mixtures. The thermodynamic and kinetic factors that govern the phase constituents are also discussed.