• 제목/요약/키워드: plant origin

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천연자원으로부터 아실코에이: 콜레스테롤아실 전달효소 저해제의 탐색 (Screening of Acyl-CoA:Cholesterol Acyltransferase(ACAT) Inhibitors from Natural Sources)

  • 김미경;권병목;배기환;최돈하;이학주;김홍은;김영국
    • 생약학회지
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    • 제30권4호
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    • pp.384-396
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    • 1999
  • Acyl-CoA: Cholesterol Acyltransferase (ACAT) is a key enzyme responsible for cholesteryl ester formation in atherogenesis and in cholesterol absorption from the intestines. In addition under pathological conditions, formation and accumulation of cholesteryl ester as lipid droplets by ACAT within macrophages constitute a characteristic feature of early lesions of atherosclerotic plaques. ACAT inhibitors are expected to be effective for treatment of atherosclerosis and hypercholesterolemia. ACAT inhibitors of natural origin have been rarely reported. In our screening program for ACAT inhibitors, 303 plants were extracted with methanol or ethanol, and screened for the inhibitory activity against ACAT from the rat liver microsome. Extracts of 13 plants including Quercus aliena, Diospyros kaki, Platycarya strobilacea and Hibiscus syriacus inhibited more than 90% of ACAT activity and 43 samples in alcohol extracts such as Magnolia obovata and Panax ginseng also inhibited more than 70% of ACAT activity at a concentration of $100\;{\mu}g/ml$.

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부산지역 대기 중 강하분진의 특성에 관한 연구 (A Study on the Characteristics of Dustfall in Pusan)

  • 김은경;옥곤;김영섭
    • 한국환경과학회지
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    • 제5권4호
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    • pp.463-471
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    • 1996
  • In order to investigate the characteristics of dustfall at eight sites in Pusan, the dustfal1 samples were collected with dust jar method from May to September 1995, and Cr, Mn, Fe, Ni, Cu, Zn, Cd and Pb were analyzed, The main results of this study are summarized as follows; 1) The total mean value of dustfall was 11.30 ton/$^{\circ}C$/month. 2) The maximum and minimum values of dustfall were industrial and resident area respectively, 3) The dustfall showed the general trend in order as May>Jun>September>July. 4) The general trend of the heavymetals in dustfall was in order as Fe>Cu>Zn>Pb>Ni>Cd>Cr>Mn any the concentrations of heavymetals had different tendencies according to sources of Pollutant meterials. 5) The Concentrations of Fe, Cu, Pb, Ni, Cd and Cr in industrial area and Mn, Pb and Zn in traffic area were high. The concentrations of heavymetals in residence area and unpolluted area were generally low. 6) Cr, Cu and Cd were influenced by the steel industry and the metal products plant and Zn was influenced by the automobiles. Mn, Fe and Ni were influenced by the soil as wet as artificial outlet. 7) The correlation between the total amount of dustfall and the concentrations of the heavymetals by month was high and the correlation between the heavymetals of the same origin was high.

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Genetic Variation and Species Identification of Thai Boesenbergia (Zingiberaceae) Analyzed by Chloroplast DNA Polymorphism

  • Techaprasan, Jiranan;Ngamriabsakul, Chatchai;Klinbunga, Sirawut;Chusacultanachai, Sudsanguan;Jenjittikul, Thaya
    • BMB Reports
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    • 제39권4호
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    • pp.361-370
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    • 2006
  • Genetic variation and molecular phylogeny of 22 taxa representing 14 extant species and 3 unidentified taxa of Boesenbergia in Thailand and four outgroup species (Cornukaempferia aurantiflora, Hedychium biflorum, Kaempferia parviflora, and Scaphochlamys rubescens) were examined by sequencing of 3 chloroplast (cp) DNA regions (matK, psbA-trnH and petA-psbJ). Low interspecific genetic divergence (0.25-1.74%) were observed in these investigated taxa. The 50% majority-rule consensus tree constructed from combined chloroplast DNA sequences allocated Boesenbergia in this study into 3 different groups. Using psbA-1F/psbA-3R primers, an insertion of 491 bp was observed in B. petiolata. Restriction analysis of the amplicon (380-410 bp) from the remaining species with Rsa I further differentiated Boesenbergia to 2 groupings; I (B. basispicata, B. longiflora, B. longipes, B. plicata, B. pulcherrima, B. tenuispicata, B. thorelii, B. xiphostachya, Boesenbergia sp.1 and Boesenbergia sp.3; phylogenetic clade A) that possesses a Rsa I restriction site and II (B. curtisii, B. regalis, B. rotunda and Boesenbergia sp.2; phylogenetic clade B and B. siamensis; phylogenetic clade C) that lacks a restriction site of Rsa I. Single nucleotide polymorphism (SNP) and indels found can be unambiguously applied to authenticate specie-origin of all investigated samples and revealed that Boesenbergia sp.1, Boesenbergia sp.2 and B. pulcherrima (Mahidol University, Kanchanaburi), B. cf. pulcherrima1 (Prachuap Khiri Khan) and B. cf. pulcherrima2 (Thong Pha Phum, Kanchanaburi) are B. plicata, B. rotunda and B. pulcherrima, respectively. In addition, molecular data also suggested that Boesenbergia sp.3 should be further differentiated from B. longiflora and regarded as a newly unidentified Boesenbergia species.

금기식(禁忌食)이 식생활(食生活) 양식(樣式)에 미치는 영향(影響) 및 의의연구(意義硏究) (A Study on Effect and Significance of Food Taboo on Korean Food Life Style)

  • 박모라;황춘선
    • 한국식생활문화학회지
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    • 제3권3호
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    • pp.245-258
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    • 1988
  • A food life style itself is substrative relations with culture, and is concerned with our daily life. Especially a food taboo comes from the intelligence which resulted from an ancestor's life experience. Accordingly, we can say a food taboo began with human appearance, settled in convention of folklore society, and forms it's own boundary todays. Since a practice of a food taboo is combinded firmly with various sociological factors such as religion, custom, and so on, it is very hard to change, even though the belife of a food taboo is not true. According to the result, first, significant factors effecting on a practice of a food taboo was a level of age, a level of education, religion, family pattern, behavior of subject and her mother for food life management, education of subject and her mother, and religion of subject and her mother. Second, in analysis of factors according to classification of food taboo a practice of a food taboo which classified to food of animal, food of plant and the other food showed significant differences, comparing religion of subject with her mother. Third, a result examined practice frequency and review of science, non science indicated that foods such as Egg of Globefish, Lettuce, Coffee, Persimmon, dried Persimmon, Soybean and Sugar are tabooed on the basis of science, and foods such as Vinegary food, Thieved food, Soup of Tangle and Dogmeat tabooed on the basis of non science. But in the case of Puja, it's basis of science is not identified. These food taboos are tabooed by more then 50% of subjects including who answerd 'there is some case to practice it' Therefore, we should continue analysis of science for the reason of a food taboo, at the same time, provide the origin and try to have a rational food life.

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연변지역 탈북 아동 및 청소년의 체위와 식생활 양상 (Anthropometric Measurements and Dietary patterns of North Korean Migrant Children in China)

  • 장남수
    • Journal of Nutrition and Health
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    • 제33권3호
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    • pp.324-331
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    • 2000
  • A deteriorating North Korean economy, coupled with a devastating natural disaster such as flooding and drought in recent years, brought about a severe food shortage and malnutrition problem which caused a migration of its population including young children to neighboring countries. We conducted a nutritional survey on a total of 436 children, aged 4-19 years old, who migrated to the China side of the border from July to September, 1999. The study subjects were interviewed by Korean-Chinese interviewers who were trained for anthropometric measurements and dietary surveys. Heights, weights, and chest circumference of the subjects were 70-90% of the South Korean reference values for the corresponding age and sex. Dietary intakes of the subjects were found to be extremely poor-the average number of food, mostly of plant origin, consumed in a day was 2.8, and the proportion of the subject who reported to take all three meals in a day while residing in North Korea was as low as 36.2%. Ninety five percent of the subjects had at least one clinical symptom related to malnutrition, 68.6% had 2-4 symptoms, and 15.1% had 5 or more symptoms. The results of this study provided an objective data for the first time on the severity of the food crisis and malnutrition problem that afflicted North Korean older children and adolescents as well as children aged 7 or under as previously reported elsewhere. the wasted and stunted children and youths prevailing in North Korea could exert a negative influence on the country's health and economy. More researches are needed in the future to investigate on the impact of malnutrition in North Korean children on the country's social, economic, and cultural state as well as on the health and nutrition situation.

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하수오(何首烏)와 백수오(白首烏)에 대한 문헌적(文獻的) 비교(比較) 고찰(考察) (A Comparative Study on the Flowery Knotweed Root and Auriculate Swallowwort Root in Medical Texts)

  • 김용율;금경수
    • 대한한의정보학회지
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    • 제15권2호
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    • pp.77-91
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    • 2009
  • Flowery Knotweed Root is the dried tuberous root of the knotweed family wheres Auriculate Swallowwort Root is the dried tuberous root of the swallowort family. Flowery Knotweed Root is also called Red Flowery Knotweed Root in China, which is dried root of Polygonum multiflorum THUMB. Chinese Flowery Knotweed Root is better known as the dried tuberous root belonging to the family Apocynaceae whereas White Flowery Knotweed Root in Korea is the dried tuberous root of Cynanchum wilfordii(Maxim) Hemsl. Up to now, while the dried root named Red Flowery Knotweed Root has been widely used in China, Auriculate Swallowwort Root has been widely used in Korea. Both the roots contrast in a striking way with the origin, shape, botanical names, other names, and chemical constituents, so administration and dosage without discrimination of both sides can be open to question. According to the literature, it is recorded that Flowery Knotweed Root and Auriculate Swallowwort Root are similar to the characteristics, properties, and actions. From this study, the result is as follows: 1. Flowery Knotweed Root and Auriculate Swallowwort Root are divided into the family Apocynaceae and the family Polygonaceae, respectively. Accordingly 2. Flowery Knotweed Root is in shape of an irregular spindle and looks reddish- brown or deep reddish-brown and the section is light yellowish-brown, while Auriculate Swallowwort Root looks yellowish-brown and the section is white or yellow. 3. Flowery Knotweed Root is reported by the Journal of the Crude Drug that the medicinals have not the same therapeutic action as Auriculate Swallowwort Root. It is recorded that the properties, channel entry, functions of Flowery Knotweed Root and Auriculate Swallowwort Root in literature have much in common. Many works on the roots of this plant has been used traditionally as a tonic are required of. In view of the results, Flowery Knotweed Root and Auriculate Swallowwort Root varies both in nature and in shape, so that the administration and dosage of the medicinals must be taken a prudent attitude.

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친환경 잡초방제를 위한 생물제초제의 상용화 현황 (Status and Perspective of Bioherbicde Development for Organic Weed Management)

  • 변종영;이증주;박기웅
    • Weed & Turfgrass Science
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    • 제6권1호
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    • pp.1-10
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    • 2017
  • 생물제초제의 이용은 농업에서 지속성을 향한 중요한 단계로 활용 될 수 있을 것이다. 유기농업 및 종합잡초관리는 보존농업에서 합성제초제와는 다르게 한 종류의 잡초관리기술에 의존하지 않아야 하며, 생물제초제는 다른 잡초관리기술과 동시에 평가되는 것이 바람직할 것이다. 우리나라 실정에 적합한 세균 및 진균으로부터 유래한 상업용 생물제초제를 선발하여 유기농업 농가에서 영농부가가치가 높은 고소득 작물을 대상으로 생물제초제 실용화 가능성을 검토할 가치가 있을 것이다. 또한 유기영농 과수원에서 비선택적으로 잡초를 방제하기 위하여 상업용으로 시판되는 옥수수 글루텐 가루 제제와 각종 식물정유 제제 등 제품에 대한 실용화 연구가 필요할 것이다.

연작지(連作地) 토양(土壤)의 독소물질(毒素物質)이 토양(土壤) pH 변화(變化)에 미치는 영향(影響) (Effects of phytotoxins on Change of pH in the Continuous Cropping Soil)

  • 정지호;이갑상;소재돈
    • 한국토양비료학회지
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    • 제24권1호
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    • pp.17-21
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    • 1991
  • 연작지(連作地) 토양(土壤)의 pH저하(低下)의 원인(原因)에 대(對)하여 수행(遂行)한 시험결과(試驗結果)를 요약(要約)하면 다음과 같다. 1. 연작연수(連作年數)가 증가(增加)할수록 독소물질(毒素物質)의 함량(含量)이 증가(增加)하였으며, 독소물질(毒素物質)의 증가(增加)가 pH를 저하(低下)시켰다. 2. 독소물질(毒素物質)에 의한 pH저하율(低下率)이 증류수와 수도수에서는 높았으나 토양(土壞)에서는 이온들의 간섭(干涉)에 의해 저하율(低下率)이 낮았다. 3. 작물(作物)의 발아(發芽)에 미치는 독소물질(毒素物質)의 영향(影響)은 benzoic acid가 p-hyd roxybenzoic acid보다 컸으며 benzoic acid 300ppm 이상(以上)에서는 발아(發芽)되지 않았다. 4. acetone으로 독소물질(毒素物質)을 추출해낸 연작지(連作地) 토양(土壤)에서는 pH가 비연작토양(非連作土壤)과 거의 같았으며 참깨의 생육(生育)도 비연작토(非連作土)의 생육(生育)정도까지 회복(回復)되었다.

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원전 안전통신망을 위한 TDMA 기반의 프로토콜 개발 (Development of TDMA-Based Protocol for Safety Networks in Nuclear Power Plants)

  • 김동훈;박성우;김정헌
    • 대한전기학회논문지:시스템및제어부문D
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    • 제55권7호
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    • pp.303-312
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    • 2006
  • This paper proposes the architecture and protocol of a data communication network for the safety system in nuclear power plants. First, we establish four design criteria with respect to determinability, reliability, separation and isolation, and verification/validation. Next we construct the architecture of the safety network for the following systems: PPS (Plant Protection System), ESF-CCS (Engineered Safety Features-Component Control System) and CPCS (Core Protection Calculator System). The safety network consists of 12 sub-networks and takes the form of a hierarchical star. Among 163 communication nodes are about 1600 origin-destination (OD) pairs created on their traffic demands. The OD pairs are allowed to exchange data only during the pre-assigned time slots. Finally, the communication protocol is designed in consideration of design factors for the safety network. The design factors include a network topology of star, fiber-optic transmission media, synchronous data transfer mode, point-to-point link configuration, and a periodic transmission schedule etc. The resulting protocol is the modification of IEEE 802.15.4 (LR-WPAN) MAC combined with IEEE 802.3 (Fast Ethernet) PHY. The MAC layer of IEEE 802.15.4 is simplified by eliminating some unnecessary (unctions. Most importantly, the optional TDMA-like scheme called the guaranteed time slot (GTS) is changed to be mandatory to guarantee the periodic data transfer. The proposed protocol is formally specified using the SDL. By performing simulations and validations using Telelogic Tau SDL Suite, we find that the proposed safety protocol fits well with the characteristics and the requirements of the safety system in nuclear power plants.

하나로 2차 냉각탑의 냉각팬 감속기의 진동분석 (Vibration Analysis of a Cooling Fan Gear Reducer of the Secondary Cooling Tower in HANARO)

  • 박용철
    • 대한기계학회논문집A
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    • 제34권7호
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    • pp.935-941
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    • 2010
  • 하나로는 한국에 설치되어 있는 열출력 30MW의 개방 수조형 연구로 이다. 이는 발전로와 달리 원자로에서 발생하는 열을 이용하여 전기를 생산하는 것 대신에 원자로의 노심 온도를 유지하기 위하여 냉각탑을 통해 대기로 이 열을 냉각한다. 냉각탑 월간 점검 중에 냉각탑 4번의 냉각팬 감속기가 기준을 상회하는 고진동을 기록하였다. 본 연구의 목적은 고진동의 원인을 찾아 정상적으로 수리하기 위함이다. 연구 방법은 FFT 스펙트럼 기법을 적용하여 고진동의 원인을 분석하였다. 그 결과 고진동 주파수는 피니언 기어의 고유 진동수의 두 배인 354Hz이었다. 피니언 기어를 점검한 결과 이빨 표면이 깨져 있었다. 깨진 피니언 기어를 제거하고 새것으로 교체한 후에는 감속기는 정상적으로 작동하였다.