• Nuclear Engineering and Technology
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• v.54 no.4
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• pp.1414-1420
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• 2022

High dose rate (HDR) brachytherapy treatment planning usually involves optimization methods to deliver uniform dose to the target volume and minimize dose to the healthy tissues. Four optimizations were used to evaluate the high-risk clinical target volume (HRCTV) coverage and organ at risk (OAR). Dose-volume histogram (DVH) and dosimetric parameters were analyzed and evaluated. Better coverage was achieved with PGO (mean CI = 0.95), but there were no significant mean CI differences than GrO (p = 0.03322). Mean EQD₂ doses to HRCTV (D₉₀) were also superior for PGO with no significant mean EQD₂ doses than GrO (p = 0.9410). The mean EQD₂ doses to bladder, rectum, and sigmoid were significantly higher for NO plan than PO, GrO, and PGO. PO significantly reduced the mean EQD₂ doses to bladder, rectum, and sigmoid but compromising the conformity index to HRCTV. PGO was superior in conformity index (CI) and mean EQD₂ doses to HRCTV compared with the GrO plan but not statistically significant. The mean EQD₂ doses to the rectum by PGO plan slightly exceeded the limit from ABS recommendation (mean EQD₂ dose = 78.08 Gy EQD₂). However, PGO can shorten the treatment planning process without compromising the CI and keeping the OARs dose below the tolerance limit.

• Journal of the Korean Regional Science Association
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• v.34 no.4
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• pp.49-60
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• 2018

To restore urban water cycle, it is necessary to improve domestic laws and regulations related to LID(Low Impact Development), which has been successfully applied to foreign countries. Thus, this study has intended to evaluate domestic legal systems related to space and environmental planning and to suggest directions to improve laws and regulations related to space and environmental planning toward extended application of LID in Korea. To reach this goal, this study has analyze the legal and institutional status of the foreign countries where LID has currently been applied, to derive the factors that laws and institutions are required to support LID based on the above analysis, to evaluate domestic laws and regulations related to space and environmental planning, and to suggest directions to improve the laws and regulations. After the evaluation, this study has found the following results. First, it was found that the concept and basic principles of LID and LID planning and associated methods were no longer mirrored in the space planning-related laws and regulations. However, these problems are not confined to LID, and result from thefailurein applying environmental planning to space planning overall. Second, it was revealed that the environmental planning-related laws and regulations defined the terminologies and targets of LID and suggested different measures to improve LID-related policies differently depending on the backgrounds ofenforcing thelaws and regulations and on environmental properties. Finally, this study has suggested the directions to improve laws and regulations related to space and environmental planning as follows. First, it is necessary to enact a law to support the extended application of LID. Second, the law to be enacted should be connected to laws, enforcement ordinances and regulations, and guidelines related to space planning. Third, environmental benefits provided by both structural and non-structural techniques of LID should be quantitatively measured.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.3
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• pp.917-926
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• 2013

This study presents the feasibility of fuzzy multi-criteria decision making (MCDM) techniques for the robust prioritization of projects. It is applied to water resources planning problem. Results from weighted sum method (WSM), analytic hierarchy process (AHP), revised analytic hierarchy process (R-AHP), and TOPSIS are compared with those from Fuzzy WSM, Fuzzy, AHP, Fuzzy R-AHP, and Fuzzy TOPSIS. For the calculation, all weights on criteria and the normalized data were obtained from the same investigation. As a result, the rankings from four MCDM techniques are slightly different while those from fuzzy MCDM show the comparatively consistent ranking. Therefore, it is desirable to use fuzzy MCDM technique when MCDM is used for the prioritization problem, since fuzzy MCDM can include the uncertain variability of input data and weighting values on criteria.

• Radiation Oncology Journal
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• v.35 no.1
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• pp.78-89
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• 2017

Purpose: To determine the optimal radiotherapy technique for gastric mucosa-associated lymphoid tissue lymphoma (MALToma), we compared the dosimetric parameters and the risk of solid secondary cancer from scattered doses among anterior-posterior/ posterior-anterior parallel-opposed fields (AP/PA), anterior, posterior, right, and left lateral fields (4_field), 3-dimensional conformal radiotherapy (3D-CRT) using noncoplanar beams, and intensity-modulated radiotherapy composed of 7 coplanar beams (IMRT_co) and 7 coplanar and noncoplanar beams (IMRT_non). Materials and Methods: We retrospectively generated 5 planning techniques for 5 patients with gastric MALToma. Homogeneity index (HI), conformity index (CI), and mean doses of the kidney and liver were calculated from the dose-volume histograms. Applied the Biological Effects of Ionizing Radiation VII report to scattered doses, the lifetime attributable risk (LAR) was calculated to estimate the risk of solid secondary cancer. Results: The best value of CI was obtained with IMRT, although the HI varied among patients. The mean kidney dose was the highest with AP/PA, followed by 4_field, 3D-CRT, IMRT_co, and IMRT_non. On the other hand, the mean liver dose was the highest with 4_field and the lowest with AP/PA. Compared with 4_field, the LAR for 3D-CRT decreased except the lungs, and the LAR for IMRT_co and IMRT_non increased except the lungs. However, the absolute differences were much lower than <1%. Conclusion: Tailored RT techniques seem to be beneficial because it could achieve adjacent organ sparing with very small and clinically irrelevant increase of secondary solid cancer risk compared to the conventional techniques.

• Journal of Korean Society of Rural Planning
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• v.25 no.4
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• pp.47-56
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• 2019

More than half of the nonpoint sources of polluting water occur in cultivating farmlands in rural areas. Agricultural nonpoint sources are discharged from large areas of farmlands, making it difficult to collect or treat pollutants. Farmland source management is known to be the most effective, and preventive management by improving farming methods is the key to reduce nonpoint pollution. At present, more than 30% of the pollutants flowing into the rivers and lakes are nonpoint pollutants caused by agricultural activities. As a countermeasure, it is more preferable to develop and apply optimal farming management techniques for agricultural nonpoint pollution management basically than to apply existing water quality management techniques. Because of the characteristics of nonpoint source pollution, it is necessary to manage farmlands in rural areas, so the willingness and competence of the residents is most important. The purpose of this study is to analyze and understand the process of changing the cognition of residents through capacity education and survey for nonpoint pollution management in rural areas. This study conducted intensive resident competency education and examined the process of changing resident awareness through three surveys. As a result of this study, it was found that continuous education and activities for rural non-point pollution management are necessary for raising awareness of residents and managing non-point pollution effectively, showing possibility of change residents' perception.

• Journal of the Korean Association of Geographic Information Studies
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• v.1 no.2
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• pp.1-13
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• 1998

The objective of this paper is to develop a cartographic model for water tank suitability for small forest fire extinction using GIS. Various digital maps were created using CAD & GIS for Amnam urban park, which is located in Seogu, Pusan city. The park had 4 small water tanks for fire extinction. The developed descriptive cartographic model identified the spatial effects of fire extinction due to the existing facilities. The prescriptive model to enhance spatial effects was developed for the determination and comparison of the effects of forest fire extinction due to the proposed facilities. This paper proved the techniques of GIS and cartographic modelling are significant for the suitability analysis of water tanks for small forest fire extinction.

• BMB Reports
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• v.50 no.12
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• pp.610-614
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• 2017

Scientists planning research that involves the use of animals are required to examine the possibilities for replacement, reduction, or refinement (the Three Rs), and their protocol must be reviewed by the Institutional Animal Care and Use Committee. Good scientific practice involving appropriate search techniques on the available Three Rs resources is essential for both ethical and scientific reasons. Appropriate experimental design and statistical analysis techniques are particularly necessary for research involving the use of animals, because this can improve animal welfare and scientific outcomes, as well as saving animal lives. There are a number of resources to help researchers improve their search techniques, experimental design strategies, and their reporting of research involving the use of animals. However, there is little specific information or resources on the Three Rs alternatives that is readily available in the Korean language. This paper outlines the common errors made by submitting researchers that have been repeatedly observed during the ethical review of experimental protocols over the last ten years, and provides information on the Korean resources available to promote good scientific practice. This could help to bridge the gap between Korean scientists and animal welfare advocates assisting scientists to improve ethical considerations and conduct responsible research.

• The Korean Journal of Nuclear Medicine
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• v.38 no.2
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• pp.115-120
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• 2004

Molecular imaging is a rapidly growing field due to the advances in molecular biology and imaging technologies. With the introduction of imaging reporter genes into the cell, diverse cellular processes can be monitored, quantified and imaged non-invasively in vivo. These precesses include the gene expression, protein-protein interactions, signal transduction pathways, and monitoring of cells such as cancer cells, immune cells, and stem cells. In the near future, molecular imaging analysis will allow us to observe the incipience and progression of the disease. These will make us easier to give a diagnosis in the early stage of intractable diseases such as canter, neuro-degenerative disease, and immunological disorders. Additionally, molecular imaging method will be a valuable tool for the real-time evaluation of cells in molecular biology and the basic biological studies. As newer and more powerful molecular imaging tools become available, it will be necessary to corporate clinicians, molecular biologists and biochemists for the planning, interpretation, and application of these techniques to their fullest potential. in order for such a multidisciplinary team to be effective, it is essential that a common understanding of basic biochemical and molecular biologic techniques is achieved. Basic molecular techniques for molecular imaging methods are presented in this paper.

• Fisheries and Aquatic Sciences
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• v.11 no.3
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• pp.166-171
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• 2008

The feasibility of photo-identification techniques for the bottlenose dolphins from Jeju Island, Korea, and the potential for dolphin watching were simultaneously evaluated in this study. During the sighting survey, a pod of bottlenose dolphins composed of approximately 30 individuals was observed in the southwestern coastal area of Jeju Island. Among 35 suitable photographs, five bottlenose dolphin individuals were identified and cataloged using unique nicks and notches on their dorsal fins. This shows that the Jeju Island dolphins can be individually identified by the nicks and notches on their dorsal fins using photo-identification techniques. Furthermore, the Jeju Island population appears to be suitable for long-term population biology studies using this technique. The potential for dolphin watching around the island would be higher if more information on the seasonal distribution, movement, and residency of this population were obtained.

• Computers and Concrete
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• v.27 no.5
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• pp.489-512
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• 2021

In this study, two powerful techniques, namely particle swarm optimization (PSO) and imperialist competitive algorithm (ICA) were selected and combined with a pre-developed ANN model aiming at improving its performance prediction of the compressive strength of concrete modified with fly ash. To achieve this study's aims, a comprehensive database with 379 data samples was collected from the available literature. The output of the database is the compressive strength (CS) of concrete samples, which are influenced by 9 parameters as model inputs, namely those related to mix composition. The modeling steps related to ICA-ANN (or neuro-imperialism) and PSO-ANN (or neuro-swarm) were conducted through the use of several parametric studies to design the most influential parameters on these hybrid models. A comparison of the CS values predicted by hybrid intelligence techniques with the experimental CS values confirmed that the neuro-swarm model could provide a higher degree of accuracy than another proposed hybrid model (i.e., neuro-imperialism). The train and test correlation coefficient values of (0.9042 and 0.9137) and (0.8383 and 0.8777) for neuro-swarm and neuro-imperialism models, respectively revealed that although both techniques are capable enough in prediction tasks, the developed neuro-swarm model can be considered as a better alternative technique in mapping the concrete strength behavior.