• Title/Summary/Keyword: place-identify

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Metabolism of Lactate Dehydrogenase in Tissues from Ldh-C Expressed Fish at Starved State (기아상태에서 Ldh-C가 발현된 어류 조직의 젖산탈수소효소의 대사)

  • Yum, Jung Joo;Kim, Gyu Dong
    • Journal of Life Science
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    • v.26 no.2
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    • pp.155-163
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    • 2016
  • Metabolism of lactate dehydrogenase (EC 1.1.1.27, LDH) was studied to identify the function of LDH-C. Tissues of LDH liver-specific Ldh-C expressed Carassius auratus and eye-specific Ldh-C expressed Lepomis macrochirus after starvation were studied. LDH activity in liver tissue from C. auratus was increased after starvation. And LDH specific activity (units/mg) and LDH/CS were increased in tissues. It means the anaerobic metabolism was taking place in C. auratus after starvation. LDH B4 isozyme was decreased in skeletal muscle and increased in heart tissue. LDH C4 isozymes those showed in eye and brain tissues were identified as liver-specific C4 isozymes and disappeared after starvation. And C hybrid in eye, A4 isozyme in brain, and both C hybrid and C4 isozyme in liver tissue were increased, respectively. In L. macrochirus, the level of variation of LDH activities was low but greatly increased especially in eye tissue and LDH A4 and AC hybrid were increased in brain tissue. The LDH activities in tissues from C. auratus and L. macrochirus remained 30.30-18.64% and 25-18.75%, respectively, as a result of the inhibition by 10 mM of pyruvate. The KmPYR values of LDH in C. auratus were increased. As a result, LDH liver-specific C4 isozyme was expressed in liver, brain and eye tissues during starvation. It seems metabolism of lactate was predominant in brain tissue. After starvation, the liver-specific LDH-C was affected more than eye-specific LDH-C.

Psychophysiological Effects of Orchid and Rose Fragrances on Humans

  • Kim, Sung Min;Park, Seongyong;Hong, Jong Won;Jang, Eu Jean;Pak, Chun Ho
    • Horticultural Science & Technology
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    • v.34 no.3
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    • pp.472-487
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    • 2016
  • This study aimed to determine the effects of floral fragrances on human brain waves and moods. A total of 44 subjects participated in this experiment. Group 1 consisted of 11 male and 14 female college students with a mean age of 24.5 years (${\pm}2.23$) and Group 2 consisted of 10 males and 9 females with a mean age of 54.3 years (${\pm}2.98$). Subjects were exposed to floral fragrances of Rosa hybrida, 'Hera' (hereafter referred to as "rose"), Cymbidium faberi (hereafter referred to as "orchid"), or odorless control flowers (hereafter referred to as "control"). Experiments took place in three rooms (rose, orchid, and control). Electroencephalographs (EEGs) were recorded during exposure to the odors and the data were processed using quantitative electroencephalographic (QEEG) techniques. The changing EEG patterns were analyzed by brain mapping and compressed spectral arrays, and the subjects' preferences (hedonic evaluations) were quantified with an A1 index. Increased activation of absolute alpha waves was verified on six of the eight EEG channels, with the right frontal and left occipital lobes exhibiting no changes and the left parietal region showing the greatest activation. According to the QEEG measurements in the electrode sites over the frontal, temporal, parietal, and occipital lobes, the strongest absolute alpha waves were induced in the parietal lobes, followed by the temporal lobes, with the other lobes showing no significant changes. On brain maps, the orchid fragrance induced greater absolute alpha and absolute mid-beta activities compared with the rose and control fragrances, and the rose fragrance induced high absolute mid-beta activation. To identify emotional responses to floral fragrances, the subjects were requested to fill in a questionnaire and the resulting odor-related emotional descriptors were analyzed using semantic differential and factor analysis. Principal component analysis identified "elegant" as the first principal component describing the floral fragrance, followed by "refreshing" and "aromatic." The subjects gave orchid higher scores for "elegant" and "refreshing," while finding rose more "aromatic." Differences in hedonic evaluation revealed by the A1 index appeared in the 65-115 sec range of scent exposure time. The subjects with ages of around 50 years showed olfactory preferences throughout the entire experimental time of 160 sec, most markedly in the later time segment (115-165 sec), showing an increasing preference with increasing exposure time. We conclude that rose fragrance can improve concentration by creating an aromatic environment conducive to a concentrated and calm state of mind, and orchid fragrance can make people feel pampered and relaxed by creating an elegant and refreshing environment.

How can the development of neighbourhood renewal strategies in Malaysia be informed by best practice and transferable lessons from developed countries (선진국 도시재생 사례비교를 통한 말레이시아 주거재생 전략의 모색)

  • Tin, Wan Jiun;Lee, Seok-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.469-486
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    • 2017
  • Economy-based urban redevelopment is the main priority in Malaysia, but has resulted in social problems such as gentrification, loss of heritage and identity, inequity, etc. Hence, it is crucial for the government to seek other alternatives rather than being solely reliant on urban redevelopment. Neighborhood renewal is a strategy involving the integration of redevelopment, rehabilitation, revitalization and preservation that aims to improve deprived areas using a more holistic approach. The aim of this paper is to review the neighborhood renewal policies in developed countries and to identify those elements that can be adopted in Malaysia. This study is conducted via a literature review. It was found that neighborhood renewal which integrates people-based, place-based and system-based policies highlights the importance of diversity, thereby aiming for resource optimization, community engagement and urban governance with the focal point of the fair, equity and systematic provision of resources. This paper concluded that neighborhood renewal in Malaysia should be initiated by locals with an emphasis on real local participation and a sustainable funding system. The government and local authorities should be observers rather than implementers.

A Study on Gasan of the Cheonggyecheon in the Joseon Dynasty (조선시대 청계천 주변의 가산(假山)에 대한 연구)

  • Kim, Myo-jung;Jung, Ki-Ho;Kim, Du-Gyu
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.34 no.4
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    • pp.26-36
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    • 2016
  • This study aims to identify the place and location of Gasan around Cheonggyecheon in the Joseon Dynasty, and also to examine the current status of their changes or disappearance in the process of modernization. On top of literature research on old document and maps related to dredging of Cheonggyecheon, the field survey to understand the actual status and location of Gasan was conducted. The study contents are like below. First, through old document and maps related to Cheonggyecheon in the Joseon Dynasty, the contents and records related to Gasan around Cheonggyecheon were selected. Such Gasan were mainly built up by dredging work of branch/streamlet in the era of King Sejong, and also the large-scale dredging during the period of King Yeongjo. Second, the location of Gasan and forest around Cheonggyecheon shown in old maps was understood. With Ogansumun(Five-arched Floodgates) as the center, they were constructed on both hills of Cheonggyecheon inside/outside of the capital city, and its surrounding branches. Third, based on the measures to create a scale map based on Susunjeondo, the location of Gasan on old maps was found on the current map, and then the current status of places expressed as Gasan was surveyed. In the results of the study, even though most of the Gasan built up around Cheonggyecheon in the Joseon Dynasty have disappeared by the urban development performed since the end of 19th century, still, there are some remains left.

Benchmarking Highway Maintenance Practices for Standardized Guideline Development (도로공사 유지관리 표준화 절차 개발을 위한 벤치마킹)

  • Ha, Minhui;Kim, Donghee;Shin, Hochul;Choi, Jaehyun
    • Korean Journal of Construction Engineering and Management
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    • v.20 no.6
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    • pp.44-56
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    • 2019
  • Recently, the paradigm of SOC investment has shifted from new construction to maintenance. This shift became more important for the highway system because it is as one of the most important SOC. In Korea, highway maintenance costs are about 20% of the total annual highway construction budget, which is about two-thirds of developed countries. In addition, establishing standardized guidelines for the highway maintenance operation is not in place. Therefore, in order for domestic road construction and maintenance technology to secure competitiveness in the global construction market, it is urgent to improve the management capacity for maintenance as well as the technology and management capacity. This study examines highway maintenance practices in OECD countries such as North America, Europe, Australia, New Zealand, and Japan to identify core elements of highway maintenance practice. It is imperative to establish a comprehensive management system based upon asset management principle. Even if the budget for the highway construction is reduced, investment in maintenance needs to be maintained.

Sea Surface Temperature Time Lag Due to the Extreme Heat Wave of August 2016 (2016년 8월 폭염에 따른 표층수온의 지연시간 고찰)

  • Kim, Ju-Yeon;Han, In-Seong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.23 no.6
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    • pp.677-683
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    • 2017
  • In this study, we examined responses to Sea Surface Temperature (SST) as the result of an intensive heat wave that took place in August 2016 and the cross correlation between SST and Air Temperature (AT) in August 2016. The data used included the SST of 8 ocean buoys, provided by the National Institute of Fisheries Science, and the AT of AWS near those 8 ocean buoys recorded every hour. To identify an appropriate data period, on FIR filter was applied. Two locations in the south sea were selected to be observed over similar a period, with a high correlation coefficient of about 0.8 and a time lag of about 50 hours between AT and SST. For the yellow sea, due to shallow waters and tidal currents, SST showed a rapid response caused by changes in AT. The east sea showed a negative correlation between AT and SST because of significant water depth and marine environment factors. By identifying the time lag between AT and SST, damage to aquatic organisms can be minimized, and we expect to develop a rapid response system for damage to the fishery industry caused by extreme heat waves.

Scientific Analysis and Conservation of Waterlogged Woods Excavated from Suyoeng-ri Site, Hwaseong, Korea (화성 수영리 유적 출토 수침목제유물의 과학적 분석 및 보존처리)

  • Lee, Kwang-Hee;Oh, Jeong-Eun;Kim, Soo-Chul
    • Journal of Conservation Science
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    • v.37 no.5
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    • pp.579-589
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    • 2021
  • Five waterlogged wood artefacts were excavated from Suyeong-ri site in Hwaseong, South Korea. The aim of the present study was to identify the species and estimate the date of manufacture and the manufacturing method of these artefacts. The study also aimed to conserve the original shapes of waterlogged wood artefacts by using the vacuum freeze drying method. The two large waterlogged woods were identified as Ulmus spp. and Morus spp., whereas one of the three small waterlogged woods was identified as Abies spp. and the other two as hard pine. Radiocarbon dating using wiggle match dated the manufacturing of these wooden artefacts between BCE 8520-8490 or BCE 8470-8290 in the Neolithic age, and a similar period was also confirmed for seed excavated from a place close to the location where the waterlogged wood artefacts were excavated. The surface of waterlogged wood artefacts had several traces of manufacturing processes - traces of tearing and chopping - were observed. Based on these observations, it was confirmed that stone adz was used to make these wooden artefacts. Thereafter, the waterlogged wood samples were conserved by immersing them into PEG#4,000 of concentration in water from 10% to 40% at room temperature(15~25℃) and subjecting them to vacuum freeze drying. However, the internal moisture was not completely removed in some thick parts of waterlogged woods by applying the general schedule such as raising the shelf temperature as the surface temperature rises. Therefore, additional study is required using the schedule-method for vacuum freeze drying of large waterlogged wood.

Modern diagnostic capabilities of neonatal screening for primary immunodeficiencies in newborns

  • Khalturina, Evgenia Olegovna;Degtyareva, Natalia Dmitrievna;Bairashevskaia, Anastasiia Vasi'evna;Mulenkova, Alena Valerievna;Degtyareva, Anna Vladimirovna
    • Clinical and Experimental Pediatrics
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    • v.64 no.10
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    • pp.504-510
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    • 2021
  • Population screening of newborns is an extremely important and informative diagnostic approach that allows early identification of babies who are predisposed to the development of a number of serious diseases. Some of these diseases are known and have effective treatment methods. Neonatal screening enables the early diagnosis and subsequent timely initiation of therapy. This helps to prevent serious complications and reduce the percentage of disability and deaths among newborns and young children. Primary immunodeficiency diseases and primary immunodeficiency syndrome (PIDS) are a heterogeneous group of diseases and conditions based on impaired immune system function associated with developmental defects and characterized by various combinations of recurrent infections, development of autoimmune and lymphoproliferative syndromes (genetic defects in apoptosis, gene mutation Fas receptor or ligand), granulomatous process, and malignant neoplasms. Most of these diseases manifest in infancy and lead to serious illness, disability, and high mortality rates. Until recently, it was impossible to identify children with PIDS before the onset of the first clinical symptoms, which are usually accompanied by complications in the form of severe coinfections of a viral-bacterial-fungal etiology. Modern advances in medical laboratory technology have allowed the identification of children with severe PIDS, manifested by T- and/or B-cell lymphopenia and other disorders of the immune system. This review discusses the main existing strategies and directions used in PIDS screening programs for newborns, including approaches to screening based on excision of T-cell receptors and kappa-recombination excision circles, as well as the potential role and place of next-generation sequencing technology to increase the diagnostic accuracy of these diseases.

Examining the Strategic Priorities for Smart City Project with Analytic Hierarchy Process Based on a Survey of Potential Residents (AHP를 활용한 스마트시티 사업의 전략적 우선순위 분석: 잠재적 주민을 대상으로)

  • Kang, Haeun;Kim, Seung-Chul;Lee, Taewon;Chang, Mikyung;Lee, Ayeon
    • Journal of Digital Convergence
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    • v.19 no.12
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    • pp.243-253
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    • 2021
  • In this study, AHP analysis was conducted on potential residents who are willing or likely to live in a smart city. The purpose is to identify priorities for strategic objectives. In order to establish a hierarchical structure for the vision, core values, and strategic goals of the smart city business, we researched domestic and overseas smart city-related academic papers and research reports, business plans, and institutional websites. After reviewing professors, researchers, experts, and focus groups, 4 2nd tier and 12 3rd tier properties were finally selected and the hierarchical structure was confirmed. As a result of AHP analysis, it was found that residents place the highest importance on quality of life in smart city projects. As a result of the analysis of the lower-level factors, it was found that safety was the most important. The priorities were analyzed in the order of living convenience, eco-friendliness, and social inequality resolution. It is expected that the results of this analysis will be able to suggest strategies to be established when promoting smart city projects in the future.

The Korean Dictionary and the Buddhist Language: Description of Popularity of Buddhism Terminologies (국어사전과 불교 언어: '불교' 영역의 전문용어 기술을 중심으로)

  • Kim, Han-saem
    • Cross-Cultural Studies
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    • v.45
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    • pp.195-218
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    • 2016
  • This paper focuses on the terminology of the dictionary as an encyclopedic element in the Buddhist language. The previous study on Buddhist language can be divided into a philosophical approach to the language itself, a review of the linguistic perspective of a specific monk, and a linguistic examination of the Buddhist language. The linguistic examination of the Buddhist language is further divided into analysis of certain Buddhist scriptures, and a study of vocabulary used throughout the Buddhist sphere. The Buddhist vocabulary in the existing Korean dictionary is found in specialized areas such as name, place name, history, and Buddhism. By advancing the generalized words of the terminologies, the meanings of the terminologies and the general words are described as polysemy. It is possible to identify the degree of transition from terminology to general word depending on the distribution of senses. In the case of Buddhist vocabulary, the usage as a general language and as a Buddhist term was given priority, and vocabulary was also derived from a Buddhist term, although it was described as a general language. If a dictionary is changed according to the language unit it contains, the difference in a Buddhist terminology for each dictionary, and a conflict between the existing academic research result and the prior description, will need to be resolved through the collaboration of religious experts, linguists, and lexicographers.