• 재활치료과학
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• 제6권2호
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• pp.47-58
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• 2017

목적: 뇌졸중 환자에게 의미 있는 작업을 기반으로 한 양측성 상지 훈련의 효과를 알아보기 위한 예비연구로 실시되었다. 연구방법: 뇌졸중으로 인한 편마비를 가진 환자 4명을 대상으로 실험군(2명)과 대조군(2명)으로 나누어 진행되었다. 2016년 5월부터 8월까지 진행하였으며, 대상자 당 총 5주간, 주 3회, 회기 당 60분의 작업기반 양측성상지훈련 중재와 전통적 양측성 상지 훈련을 각 각 실시하였다. 중재 전 후로 EMG, 가속도계, ARAT, Y-BAT, SIS, COPM를 실시하여 각 군간 비교 하였다. 결과: 실험군은 대조군 보다 노쪽 손목폄근과 앞 어깨 세모근의 근 활성도, SIS에서 손 기능(Hand function), 기억력(Memory)항목을 제외한 모든 항목에서 중재 전 후 큰 변화량을 나타냈으며, 양손의 사용량을 측정한 가속도계와 COPM, Y-BIT, ARAT평가의 잡기(grasp), 집기(pinch), 대동작 (gross movement)항목에서 실험군은 대조군 보다 중재 전 후 큰 변화량을 나타냈다. 결론: 본 연구를 통해 작업기반 양측성 상지 훈련이 신경학적 변화를 통한 상지기능 회복 및 사회참여 등에 효과적임을 알 수 있었다. 추후 연구에서는 작업기반 양측성 상지 훈련 프로토콜의 내용에 대해 높은 내용 타당도를 확보하기 위한 개발 연구가 필요할 것이며, 이를 토대로 많은 뇌졸중 환자를 대상으로 한 무작위대조군 실험 연구를 통한 효과 검증과 효과지속성에 대한 검증이 필요할 것이다.

• Journal of Advanced Marine Engineering and Technology
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• 제39권9호
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• pp.881-889
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• 2015

해양온도차발전은 해양의 표층수와 심층수의 온도차를 이용하여 발전하는 유기랭킨사이클이다. 작동유체와 사이클 구성은 유기랭킨사이클의 열역학적 효율에 큰 영향을 미치는 요소이다. 본 연구에서는 작동유체와 사이클에 따른 해양온도차발전시스템의 성능분석을 수행하였다. 고전적인 단순 랭킨사이클과 단순 랭킨사이클의 대안으로 제시되고 있는 개방형 및 통합형 재생 랭킨사이클 그리고 칼리나 사이클이 본 연구에서 고려되었으며, 작동유체로는 9종의 단일냉매와 3종의 혼합냉매를 본 연구에 적용하였다. 사이클의 성능분석에는 핀치포인트온도차를 일정하게 유지하는 핀치포인트분석이 적용되었다. 성능분석결과를 살펴보면, 단순 랭킨사이클과 개방형 및 통합형 재생 랭킨사이클의 경우 RE245fa2를 작동유체로 사용하며, 칼리나 사이클의 경우 $NH_3/H_2O$의 질량비가 0.9:0.1일 때 열역학적 효율이 가장 높았다. 한편, 개방형 및 통합형 재생 랭킨사이클과 칼리나 사이클을 해양온도차발전시스템에 적용할 경우 단순 랭킨사이클과 비교하여 각각 약 2.0 %, 1.0%, 10.0%의 효율 향상을 기대할 수 있었다.

• 한국재료학회지
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• 제3권6호
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• pp.645-651
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• 1993

Bulk반절연 기판 웨이퍼에 이온 주입법에 의한 기존의 GaAs집적회로 제작시 발생하는 문제점을 보완하고자 반절연 기판 위에 반절연성의 고저항 GaAs 에피층을 성장하는 연구를 수행하였다. 먼저 반절연 기판의 EPD분포를 조사하고, MOCVD와 MBE법을 이용하여 undeped GaAs반절연성 에피층을 성장시켜 실제 집적회로의 제작에 적합한지를 평가하였다. 평가방법은 반절연성 에피\ulcorner을 buffer층으로 성장시킨 에피 기판에 ungated FET를 제작하여, 이 반절연성 에피\ulcorner을 통한 누설전류를 측정하고, 또한 반절연 기판의 EP분호의 영향을 조사하였다. 누설 전류의 측정결과 비교적 주설 전류가 큰 1$\mu\textrm{m}$ 두께의 MOCVD시료에서도 270nA/mm로 FET의 pinch-off에는 영향을 주지 못하는 매우 작은 누설 전류 값을 나타내었다. 또한 누설전류의 분포가 반절연 기판의 EPD분포와 일치하는 것을 발견하여, 에피층의 quality에 기판의 결함이 미치는 영향을 확인하였다. MBE법으로 성장한 2$\mu\textrm{m}$ 두께의 undoped burrer층 시료는 휠씬 좋은 특성을 나타내었으며, 매우 균일하고 낮은 누설전류(40nA/mm)가 측정되었다.

• Journal of Ginseng Research
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• 제15권1호
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• pp.6-12
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• 1991

The analgesic effect of morphine was antagonized in mice pretreated with ginseng total saponin intraperitoneally, intracerebrally and intrathecally. The antagonized effects of morphine analgesia were reversed predominantly by treatment with L-3, 4-dihydroxyphenylalanine in the tail pinch test and 5-hydroxytryptophan in the tail flick test respectively. These indicate that the antagonistic action of ginseng total saponin might be due to their inhibitions of the activation of descending ihibitory systems at the cerebral site as well as spinal. In addition, any appreciable changes of brain biogenic monoamine levels were not observed in mice pretreated with ginseng total saponin at various time intervals. These results obtained suggest that a newly equilibrated state of neurologic function could be found in mice pretreated with ginseng total saponin, and modification of neurologic function in the mechanism for the antagonism of morphine analgesia by ginseng total saponin was more important than the changes of brain biogenic monoamine levels.

• The Korean Journal of Physiology
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• 제22권1호
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• pp.89-100
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• 1988

Effect of clonidine on the dorsal horn cell responses to mechanical stimulations were studies in 3 spinalized cats and 10 cats with intact spinal cord. The type of dorsal horn cells was determined according to their response patterns to four graded mechanical stimulations (brush, pressure, pinch and squeeze) applied to the respective receptive fields. In the present study the results obtained only from the wide dynamic range (WDR) cells were included. The responses of the WDR cells to noxious mechanical stimuli were selectively suppressed following intravenous administration of clonidine into the experimental animals. The clonidine-induced changes in responses of the WDR cells to mechanical stimulation were not affected by naloxone or propranolol whereas effect of clonidine on WDR cell responses was almost completely abolished after intravenous administration of yohimbine. Also in the spinalized cats results parallel to those observed in cats with intact spinal cord were obtained. The results of present study strongly implies that analgesic action of clonidine can be mediated through excitation of ${\alpha}_{2}-adrenoceptor$ even at the spinal cord level without supraspinal mechanism.

• 대한간호학회지
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• 제36권2호
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• pp.403-414
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• 2006

Purpose: The purpose of this study was to investigate the effects of constraint-induced (CI) movement using self-efficacy on U/E function of chronic hemiplegic patients. CI movement discourages the use of the unaffected U/E, combined with intensive training of the affected U/E. Method: A non-equivalent pretest-posttest design was used. Study subjects were 40 hemiplegic patients conveniently selected from 2 different community health centers. The experimental subjects participated in the CI movement program for 6 hours daily over a period of two weeks. The exercises for affected U/E consisted of warming up, main exercise and ADL practice. To encourage the participants' behaviors self-efficacy enhancing strategies were used, which included performance accomplishment, vicarious experience, verbal persuasion and emotional arousal. Result: After 2 weeks of treatment, the grip power, pinch power, wrist flexion/extension, elbow flexion, and shoulder flexion/extension were significantly higher in the experimental subjects than in the control subjects. However, there was no significant difference in hand functions of the two groups. Conclusion: The above results show that the constraint-induced movement using self-efficacy could be an effective nursing intervention for improving U/E function of chronic hemiplegic patients. Long term studies are needed to determine the lasting effects of constraint-induced movement.

• Archives of Plastic Surgery
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• 제36권2호
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• pp.194-199
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• 2009

Purpose: The orbital fat buldging may cause irregular contour of lower eyelid, which is not youthful appearance. The conventional method of fat excision may cause the eyeball to move backward and downward, making enopthalmia is inevitable. The transcutaneous approach to reach the orbital septum can increase the risks of scleral show resulting from scarification at the level of the septum orbicularis junction and damaging the vertical motor branches of the preseptal orbicularis oculi muscle of the lower eyelid. Method: From July 2007 to March 2008, total of 21 patients underwent transconjunctival capsulopapebral fascia fixation procedure. In 8 patients, the herniated fat pad of the lower eyelid was relocated back into the orbit without external skin excision using capsulopalpebral fascia fixation. But in 13 patients, excision of redundant skin of the lower eyelid was performed using pinching technique, not involving orbicularis oculi muslce. In 5 patients, lateral canthotomy was done bilaterally for good visual field. In 6 patients, lateral canthopexy was also combined to correct loosening of lower eyelid. Results: Most of the patients were satisfied after at least 5 months of follow up. No patient showed scleral show. But 2 patients complained of undercorrection slightly, without secondary operation in 1 patient and re - capsulopalpebral fascia fixtation through transconjunctival approach in another patient. Conclusion: Orbital fat repositioning using transconjunctival capsulopalpebral fascia fixation is a good procedure to show youthful appearance without increasing the risk of scleral show and also showed fast recovery compared to the conventional transcutaneous approach.

• Archives of Reconstructive Microsurgery
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• 제10권2호
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• pp.86-92
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• 2001

Failure of replantation is inevitable in finger replantation surgery, around 10% of failure rate are reported in many authors. Management of the failed finger replantation is one of big dilemma to microsurgeons. We report 5 cases of thumb reconstruction after failure of replantation. The reconstructive surgery composed with early debridement of soft tissue that are under gangrenous processing, extract the phalangeal bone without any soft tissues. Osteosynthesis of the extracted phalangeal bone with host phalangeal bone. The exposed bony portion covered with vascularized flaps such as revered radial forearm pedicled flap, free radial forearm flap and neurovascular island finger flap. This procedure underwent within a week after vascular insufficiency developed. All of the flaps are survived, bone union achieved within 3 months. The function and external appearance of the reconstructed thumb were encouraging; Pinch Power was average 1.2 Pounds. Early removal of necrotizing soft tissue followed by covering none vascular phalangeal bone which extracted from the dead phalanx with vascularized flap is one of the useful alterative solutions in failed replantation surgery in hand.

• Archives of Reconstructive Microsurgery
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• 제16권2호
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• pp.86-92
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• 2007

Failure of reattachment of finger is inevitable in replantation surgery and that failure rate is about 10 % are reported in many authors. Management of the failed finger replantation is challenge to microsurgeons. We report 7 cases of thumb reconstruction after failure of replantation. The reconstructive surgery composed with early debridement of soft tissue that are under gangrenous processing, extract the phalangeal bone without any soft tissues. Osteosynthesis of the extracted phalangeal bone with host phalangeal bone. The exposed bony portion covered with vascularized flaps such as reverse radial forearm pedicled flap, free radial forearm flap and neurovascular island finger flap. This procedure underwent within a week after vascular insufficiency developed. All of the flaps are survived, bone union achieved within 3 months. The function and external appearance of the reconstructed thumb were encouraging; pinch power was average 1.2 pounds. Early removal of necrotizing soft tissue followed by covering none vascular phalangeal bone which extracted from the dead phalanx with vascularized flap is one of the useful alterative solutions in failed replantation surgery in hand.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제48권3호
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• pp.161-166
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• 1999

We investigate the device characteristics of the separated shorted-anode LIGBT (SSA-LIGBT), which suppresses effectively the negative differential resistance regime, by 2-dimensional numerical simulation. The SSA-LIGBT increases the pinch resistance by employing the highly resistive n-drift region as an electron conduction path instead of the lowly resistive n buffer region of the conventional SA-LIGBT. The negative differential resistance regime of the SSA-LIGBT is significantly suppressed as compared with that of the conventional SA-LIGBT. The SSA-LIGBT shows the lower forward voltage drop than that of the conventional SA-LIGBT.