• 생물정신의학
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• 제22권2호
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• pp.29-33
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• 2015

The brain maintains homeostasis and normal microenvironment through dynamic interactions of neurons and neuroglial cells to perform the proper information processing and normal cognitive functions. Recent post-mortem investigations and animal model studies demonstrated that the various brain areas such as cerebral cortex, hippocampus and amygdala have abnormalities in neuroglial numbers and functions in subjects with mental illnesses including schizophrenia, dementia and mood disorders like major depression and bipolar disorder. These findings highlight the putative role and involvement of neuroglial cells in mental disorders. Herein I discuss the physiological roles of neuroglial cells such as astrocytes, oligodendrocytes, and microglia in maintaining normal brain functions and their abnormalities in relation to mental disorders. Finally, all these findings could serve as a useful starting point for potential therapeutic concept and drug development to cure unnatural behaviors and abnormal cognitive functions observed in mental disorders.

• 농업과학연구
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• 제40권3호
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• pp.191-196
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• 2013

This study was conducted to investigate the effect of temperature during transportation and continuing shelf-life on fruit quality and the occurrence of physiological disorder to set up the appropriate exportation temperature condition in Asian pear (Pyrus pyrifolia Nakai) 'Hanareum'. In the experiment of simulated exportation headed for USA, the fruits transported at $1^{\circ}C$ showed less weight loss than those of $5^{\circ}C$. Market temperature appeared as a key factor for keeping freshness of exported pear fruits rather than transportation temperature. Quality factors such as high flesh firmness and low incidence of fruit rot and physiological disorders including core breakdown and pithiness were attained at the fruits maintained at $18^{\circ}C$. Approximately two times higher incidence of physiological disorders and of fruit decay rates were observed in the fruits distributed at $25^{\circ}C$ than the those of $18^{\circ}C$. Therefore, temperature management during marketing resulted as an important factor for maintaining fruits quality in the process of pear fruit exportation.

• Clinical and Experimental Pediatrics
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• 제49권1호
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• pp.1-5
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• 2006

Several physiological skin changes such as vernix caseosa, cutis marmorata, physiologic desquamation, and sebaceous hyperplasia have been described in the neonatal period. There are also clinical characteristics of skin peculiar to neonate and infancy. Skin disorders observed during neonatal and infancy period can be divided into transient skin lesions, birth marks, and other diseases. Transient skin lesions include milia, sebaceous gland hyperplasia, erythema neonatorum, transient neonatal pustular melanosis, and acne neonatorum. Nevocellular nevus, mongolian spot, vascular malformation, hemangioma, epidermal nevus, and sebaceous nevus belong to birth marks. There are several common skin diseases such as miliaria, diaper dermatitis, atopic dermatitis, seborrheic dermatitis, and cutaneous candidiasis.

• The Korean Journal of Pain
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• 제27권1호
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• pp.16-22
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• 2014

Psychosomatic disorders are defined as disorders characterized by physiological changes that originate partially from emotional factors. This article aims to discuss the psychosomatic disorders of the oral cavity with a revised working type classification. The author has added one more subset to the existing classification, i.e., disorders caused by altered perception of dentofacial form and function, which include body dysmorphic disorder. The author has also inserted delusional halitosis under the miscellaneous disorders classification of psychosomatic disorders and revised the already existing classification proposed for the psychosomatic disorders pertaining to dental practice. After the inclusion of the subset (disorders caused by altered perception of dentofacial form and function), the terminology "psychosomatic disorders of the oral cavity" is modified to "psychosomatic disorders pertaining to dental practice".

• 원예과학기술지
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• 제17권6호
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• pp.737-741
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• 1999

본 조사는 생리장해 연구의 기초자료를 얻기 위하여 1998년에 경북 시설 과채류 주산지에서 재배실태와 생리장해에 대하여 농가 현장방문을 통하여 실시되었다. 재배시설의 형태는 단동 또는 연동의 철 파이프 PE하우스가 대부분이며, 딸기, 참외, 수박은 단동 PE하우스, 그리고 토마토와 오이는 연동하우스를 이용하였다. 전체 조사농가 중 단작의 비율은 56.8%, 그리고 윤작은 40.9%로 나타났다. 시설내의 관수는 점적만 하는 농가는 전체 농가의 38.6%이다. 연작연수는 전제적으로 5년 미만의 농가가 38.1%였으며, 10년 이상 된 농가도 20.5%에 달하였다. 재배품종은 작물별로 다양하나, 특히 오이와 수박에서 다양하였다. 딸기의 기형과는 3월에 발생이 많았고 수확종기에 소과가 나타났다. 영양결핍에 의한 황화증상은 5월 이후에 많았고, 월동기에 왜화와 생육초기에 런너발생 등이 관찰되었다. 토마토는 9~11월에 열과, 10월과 2~4월에 기형과, 7~9월에 배꼽썩음과 등이 심하였으며, 순멎이, 이상경, 영양결핍증 등도 관찰되었다. 오이는 곡과, 곤봉과, 어깨빠진과 등 기형과는 11~12월에 심하게 나타났으며, 5~7월에 낙하산엽 증상 등이 조사되었다. 참외의 기형과와 발효과는 3~5월에 심하였고 수박의 열과도 4~5월에 많았으며 변형과는 8월에 나타났다. 식물체에는 영양결핍인 황화증상이 다수의 농가에서 발견되었다. 생리장해에 대한 인식은 병해충에 대한 인식보다 강하지 못할 뿐 아니라 장해의 동정이나 방제법에 소홀한 점들이 많았다. 생리장해 발생원인으로는 토양환경 불량과 온도관리의 미흡이라고 응답하였으며 대책으로는 하우스 환경관리를 잘 해야 한다고 대부분의 농가가 응답하였다.

• Molecules and Cells
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• 제45권11호
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• pp.781-788
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• 2022

Proline plays a multifaceted role in protein synthesis, redox balance, cell fate regulation, brain development, and other cellular and physiological processes. Here, we focus our review on proline metabolism in neurons, highlighting the role of dysregulated proline metabolism in neuronal dysfunction and consequently neurological and psychiatric disorders. We will discuss the association between genetic and protein function of enzymes in the proline pathway and the development of neurological and psychiatric disorders. We will conclude with a potential mechanism of proline metabolism in neuronal function and mental health.

• 한국작물학회지
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• 제28권3호
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• pp.328-333
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• 1983

수도기계이앙재배를 위한 상자육묘에 있어서 발생하기 쉬운 입고병이나 생리적 장해인 뜸묘를 방지하기 위한 예방적 기술대책으로서 3-Hydroxy-5-methylisoxazole(상품명 : 다찌가렌)을 비롯한 채소의 로균병방제약제인 SF 8002와 벼의 도열병방제약제인 Isoprothiolane(상품명 : 후지왕)등을 상토 또는 육묘중에 처리함으로서 입고병과 뜸묘의 발생억제효과와 함께, 이들 약효가 묘의 생육과 생리적 활력 증대(건묘육성)에 미치는 영향을 연구 검토한 바 그 결과를 요약하면 다음과 같다. 1. 묘의 지상부를 절단하고 뿌리로부터 흡수된 수분이 야간에 엽초부에 있는 통도조직을 통해서 절단부에 맺치는 일필량의 다소로서 뿌리의 생리적 활력을 진단한 바 Hydroxyisoxazole 19%, SF 8002 24%, Isoprothiolane 35%, Metalayl 41%의 순으로 일필량이 많았다. 2. 20일묘의 뿌리를 절제 사경재배조건에 삽식하여 활착과 관련이 있는 신근발생량을 보면 약제처리에 의한 신근의 발근력이 크게 증가하였으며, 신근발근력과 일필량간에는 고도의 정의 유의상관 관계를 인정할 수 있었다. 3. 35일묘를 대상으로 묘를 뽑아 수평으로 높이고 뿌리를 포수상태로 흡수시키면서 지상부의 굴기력을 측정한 바, 공시약제간 차이는 있으나 무처리에 비해 현저히 빠른 것으로 보아 이들 약제처리에 의한 묘의 활착력이 크게 증대됨을 확인할 수 있다. 4. 광합성능력과 직접 관계가 깊은 기공의 개도에 의한 절단한 지상부의 수분감소율의 추이를 보면 Hydroxyisoxazole 및 SF 8002 처리구가 다같이 수분감소율이 큰 것으로 보아 생리활성의 증대가 큰 것으로 해석되었다. 5. 파종후 20일묘를 립모상태하에서 지상부를 절단한 후 지상부의 재생능력을 보면 Isoprothiolane을 제외한 다른 약제처리에서 다같이 높았으며, 특히 SF 8002 및 Metalaxyl이 현저하였다. 6. 이들 살균제처리구는 묘의 생리적 장해인 뜸묘의 방제효과가 뚜렷하였으며, 이같은 효과는 앞에서 지적한 바와 같이 이들 약제가 가지는 생육조절작용으로서의 생리적 활력 증대가 뜸묘의 발생을 예방적으로 방제하는 간접효과라고 해석된다.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1996년도 International Conference on Agricultural Machinery Engineering Proceedings
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• pp.632-637
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• 1996

An expert system for cucumber disease and nutritional disorders(ESCD) was developed using HCLIPS in which several interface programs were added to CLIPS developed in NASA. The knowledges for constructing knowledge base was obtained from interviews with farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which could frequently found in fields and greenhouses. Validation of ESCD by twenty -four experts proved a possibility of its practical use for diagnosing cucumber diseases and nutritional disorders in the future.

• 한국작물학회:학술대회논문집
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• 한국작물학회 1991년도 추계 학술대회지
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• pp.22-22
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• 1991

• 농업과학연구
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• 제44권3호
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• pp.332-338
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• 2017

This study was conducted to investigate the effect of 1-methylcyclopropene (1-MCP), a known ethylene action inhibitor, on fruit quality and incidence of physiological disorders during a simulated marketing period in new mid-season Asian pear (Pyrus pyrifolia Nakai) 'Changjo'. Flesh firmness of untreated control fruits was maintained with a hardness of 20.2 N until day 14 of simulated marketing but decreased rapidly to 6.2 N at day 21 of simulated marketing; losing its commercial quality. However, the firmness of 1-MCP treated fruits remained high (> 20.7 N) during the same period. Quality indices such as soluble solids content and titratable acidity in 'Changjo' pear did not show any significant differences during simulated marketing period regardless of 1-MCP treatment. For the difference in skin color, redness ($a^*$) tended to increase as simulated marketing period became longer, and 1-MCP treatment delayed this change by 7 days compared to the untreated fruits. No decrease occurred in ethylene production level with 1-MCP treatment in 'Changjo' pear. Meanwhile, 1-MCP treated pears showed a significantly lower respiration rate compared to the untreated fruits. Also, 1-MCP treatment effectively reduced the incidence of physiological disorders including internal flesh browning and mealiness symptoms during simulated marketing periods of 21 and 14 days, respectively. Therefore, we conclude that the use of 1-MCP is recommended for quality maintenance and for prevention of physiological disorders during simulated marketing periods of ${\geq}7days$ for mid-season Asian pear 'Changjo'.